• The Korea Genome Conference
• /
• 2002.08a
• /
• pp.39.1-39.1
• /
• 2002

• Proceedings of the Korean Society of Life Science Conference
• /
• 2006.09a
• /
• pp.44.2-44.2
• /
• 2006

• Proceedings of the Korean Society of Plant Pathology Conference
• /
• 2002.09a
• /
• pp.196.2-196
• /
• 2002

• Proceedings of the Korean Society of Plant Pathology Conference
• /
• 2004.10a
• /
• pp.30-31
• /
• 2004

See Full Text

• Journal of Applied Biological Chemistry
• /
• v.50 no.4
• /
• pp.288-292
• /
• 2007

• 대한생식의학회:학술대회논문집
• /
• 2006.11a
• /
• pp.119-119
• /
• 2006

• Journal of Microbiology and Biotechnology
• /
• v.13 no.2
• /
• pp.317-320
• /
• 2003

Genome-wide systematic deletion mutants were generated using a PCR-based targeted mutagenesis of Schizosacchaaromyces pombe. In a drug-sensitivity assay using thiabendazole(TBZ), an inhibitor of microtubule assembly, a heterozygous nda2 mutant ($nda2^+/nda2^-$), deleting one copy of nda2 encoding the microtubule subunit alpha1 demonstrated a distinct sensitivity to TBZ, indicating TBZ-induced haploinsufficiency. This result suggests that profiling drug-induced haploinsufficiency can be exploited to identify target genes for drugs and discover new drugs.

• 대한예방의학회:학술대회논문집
• /
• 2001.10a
• /
• pp.411-411
• /
• 2001

• 대한예방의학회:학술대회논문집
• /
• 2002.10a
• /
• pp.524-524
• /
• 2002

• 대한예방의학회:학술대회논문집
• /
• 2002.05a
• /
• pp.87-87
• /
• 2002