• Title/Summary/Keyword: Genome

Search Result 5,265, Processing Time 0.033 seconds

A Short History of the Genome-Wide Association Study: Where We Were and Where We Are Going

  • Ikegawa, Shiro
    • Genomics & Informatics
    • /
    • v.10 no.4
    • /
    • pp.220-225
    • /
    • 2012
  • Recent rapid advances in genetic research are ushering us into the genome sequence era, where an individual's genome information is utilized for clinical practice. The most spectacular results of the human genome study have been provided by genome-wide association studies (GWASs). This is a review of the history of GWASs as related to my work. Further efforts are necessary to make full use of its potential power to medicine.

Cytogenetic Studies of Scila scilloides Complex from Korea I. Distribution of Genomes and Composition and Frequencies of B Chromosome (한국 무릇(Scilla scilloides Complex)의 세포유전학적 연구 I. 게놈에 따른 분포 및 B염색체의 조성과 출현 빈도)

  • 최혜운
    • Journal of Plant Biology
    • /
    • v.33 no.4
    • /
    • pp.237-242
    • /
    • 1990
  • Geographical distribution of diploid plant with AA genome (2n=16) and allotetraploid with AABB genome (2n=34) of Scilla scilloides Complex from Korea has been studied. The composition and frequencies of B chromosomes ere also investigated. Plants with AABB genome were predominant over AA genome plants. A mixed population of AA and AABB genome plants was found for the first time. Aneuploid plants have not been found. Chromosomes of AA genome were composed of three pairs of metacentric, two pairs of submetacentric, two pairs of subtlocentric and one pair of telocentric chromosomes, whereas BB genome was four pairs of metacentric and five pairs of subtelocentric chromosomes. B chromosomes were classified into two categories, isochromosome (F) and chromosome fragment (f). The frequencies of B chromosomes were 43% in AA genome plants and 44% in AABB genome plants. The number of B chromosome ranged from 1 to 3 and 1 to 7 in AA and AABB genome plants, respectively. B chromosome combinations were F and F+f in AA genome plants and F, F+f and f in AABB genome plants.

  • PDF

PrimateDB: Development of Primate Genome DB and Web Service

  • Woo, Taeha;Shin, Gwangsik;Kang, Taewook;Kim, Byoungchul;Seo, Jungmin;Kim, Sang Soo;Kim, Chang-Bae
    • Genomics & Informatics
    • /
    • v.3 no.2
    • /
    • pp.73-76
    • /
    • 2005
  • The comparative analysis of the human and primate genomes including the chimpanzee can reveal unique types of information impossible to obtain from comparing the human genome with the genomes of other vertebrates. PrimateDB is an open depository server that provides primate genome information for the comparative genome research. The database also provides an easy access to variable information within/between the primate genomes and supports analyzed information, such as annotation and retroelements and phylogeny. The comparative analyses of more primate genomes are also being included as the long-term objective.