• Title/Summary/Keyword: Genetic inheritance

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A Cephalometric Study on the Inheritance of Craniofacial Complex (두개안면골격의 유전성에 관한 측모두부방사선 계측학적 연구)

  • Kim, Joong-Han;Lee, Dong-Joo
    • The korean journal of orthodontics
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    • v.16 no.2
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    • pp.69-80
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    • 1986
  • This study was undertaken to investigate the inheritance in craniofacial complex among Korean familial members. The subjects were 160 lateral cephalometric radiographs from 45 families. Standard product-moment correlation coefficients(r) were calculated for the measurements between the familial pairings. Further, coefficients of $determination(r^2)$ were calculated and multiple regression analyses were performed to assess the use of parents' record for predicting an offspring's craniofacial features. The following results were obtained. 1. First-degree relatives had a high level of significant correlations which were compatible with a polygenic theory of inheritance than those of non-relatives. 2. Mother-daughter pair had the highest significant correlations, then mother-son and father-son pairs, and, finally, father-daughter pair had the lowest significant correlations. 3. The genetic influence was higher in anterior cranial base length and genial angle. In contrast, the environmental influence was higher in posterior border of ramus, maxillary ant. teeth, maxillary & mandibular apical bases and Gla-P. occ. 4. The predictability of offspring's cranio-facial growth could be improved by using multiple measurements from both parents than those from father or mother only.

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Inheritance of Cyst Nematode Resistance in a New Genetic Source, Glycine max PI 494182

  • Arelli, Prakash R.;Wang, Dechun
    • Journal of Crop Science and Biotechnology
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    • v.11 no.3
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    • pp.177-180
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    • 2008
  • Worldwide, cyst nematode(Heterodera glycines Ichinohe) is the most destructive pathogen of cultivated soybean. In the USA, current annual yield losses are estimated to be nearly a billion dollars. Crop losses are primarily reduced by the use of resistant cultivars. Nematode populations are variable and have adapted to reproduce on resistant cultivars over time because resistance primarily traces to two soybean accessions. It is important to use diverse resistance sources to develop new nematode resistant cultivars. Soybean PI 494182 is a recent introduction from Japan and found to be resistant to multiple nematode populations. It is yellow seeded and maturity group 0. We have determined inheritance of resistance in PI 494182 using $F_{2:3}$ families derived from cross PI 494182 X cv. Skylla. Skylla is a susceptible parent. Three nematode populations, races 1, 3, and 5, corresponding to HG types 2.5.7, 0, and 2.5.7 were used to bioassay 162 $F_{2:3}$ families in greenhouse experiments. Based on Chi-square tests, a two-gene model is proposed for resistance to race 1 and a three-gene model is proposed for conditioning resistance to both races 3 and 5. Correlation coefficient analysis indicated that some genes conditioning resistance to races 1, 3, and 5 are shared or closely linked with each other. These results will be useful to soybean breeders for developing soybean cultivars for broad resistance to nematodes.

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Inheritance Analysis of Giant Embryo Mutation Induced by T-DNA Insertion in Rice

  • Qin, Yang;Kim, Suk-Man;Park, Hee-Yeon;Sohn, Jae-Keun
    • Korean Journal of Breeding Science
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    • v.41 no.1
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    • pp.9-15
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    • 2009
  • Recently, giant embryonic rice and functional rice food are preferred by more consumers, which are attributed to the fact that the embryo has high concentrations of essential amino acids, fatty acids, and vitamins relative to other parts of rice grains. In this report, the heredity and stability of giant embryo mutations in successive generations were analyzed regarding a giant embryonic line, 'P47', induced by T-DNA insertion and a $F_2$ population from a cross between 'P47' and 'Junam'. The mutant lines with increases of 1.5, 1.7 and 1.8 times on embryo length, width and 100-embryo weight to those of the control showed stable inheritance across three generations. The continuous frequency distributions of embryo size in the $F_2$ population showed that the embryo size is a quantitative trait of polygene controlled. In addition, wide range of transgressive segregations of six traits affecting embryo size confirmed exchange of genetic materials and recombination between genes controlling embryo size. Five giant embryo mutant lines selected from the $F_2$ population will be used for artificial selection and improvement of giant embryonic varieties.

Long-Term Breeding Strategies for Genetic Improvement of Buffaloes in Developing Countries - Review -

  • Chantalakhana, C.;Skunmun, P.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.7
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    • pp.1152-1161
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    • 1999
  • Buffalo raising to produce milk, meat, and draught power as well as other products continues to be important in Asia and other parts of the world in the next century due to an increase in the demand for such products and the unique roles of buffaloes in rural economy. Long-term breeding strategies with special relevance to present and future farming systems prevailing in developing countries are proposed. Some important considerations in the choice of certain breeding strategies for long-term genetic improvement in buffaloes are discussed. Some recent research results in genetic selection and crossbreeding of buffaloes are highlighted. A review of genetic inheritance of buffalo traits is presented as well as a discussion Of certain quality traits of buffaloes which deserve future research for improvement.

Genetic approaches toward understanding the individual variation in cardiac structure, function and responses to exercise training

  • Kim, Minsun;Kim, Seung Kyum
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.1
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    • pp.1-14
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    • 2021
  • Cardiovascular disease (CVD) accounts for approximately 30% of all deaths worldwide and its prevalence is constantly increasing despite advancements in medical treatments. Cardiac remodeling and dysfunction are independent risk factors for CVD. Recent studies have demonstrated that cardiac structure and function are genetically influenced, suggesting that understanding the genetic basis for cardiac structure and function could provide new insights into developing novel therapeutic targets for CVD. Regular exercise has long been considered a robust nontherapeutic method of treating or preventing CVD. However, recent studies also indicate that there is inter-individual variation in response to exercise. Nevertheless, the genetic basis for cardiac structure and function as well as their responses to exercise training have yet to be fully elucidated. Therefore, this review summarizes accumulated evidence supporting the genetic contribution to these traits, including findings from population-based studies and unbiased large genomic-scale studies in humans.

Identification and Characterization of Novel Sequences of ev21-K Locus for Feather-Sexing in Chickens

  • Eun Jung Cho;Sea Hwan Sohn
    • Korean Journal of Poultry Science
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    • v.51 no.2
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    • pp.117-125
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    • 2024
  • This study aimed to find genetic markers for breed-independent identification of early- and late-feathering chickens. We explored the novel sequences of the ev21-K locus associated with late-feathering and investigated its characterization. Additionally, the genetic transmission pattern of the identified sequences were investigated to understand its potential application in auto-sexing lines. A total of 707 chickens from 5 chicken breeds were employed for the study. The ev21-K locus was identified through a comparative analysis of the ev21 gene and the K gene related to feather development. For analysis of identified loci, specific primers for the target sequences were prepared and polymerase chain reaction (PCR) was performed to obtain the products, and then their nucleotide sequences were analyzed. Crossbreeding tests of early-feathering and late-feathering chickens were conducted to examine the genetic transmission patterns of the identified sequences. The results showed that the identified 230 bp ev21-K locus, which named as ev21-related K specific sequences were 99% homology with the ev21 gene. PCR analysis confirmed its presence exclusively in late-feathering chickens. Comparative analyses across tissues, breeds, and ages demonstrated the sequences consistency in identifying late-feathering chickens. Genetic transmission patterns were investigated through crossbreeding tests, revealing sex-linked inheritance and consistent segregation with feathering phenotypes. The inheritance patterns of the ev21-related K specific sequences demonstrated that this locus follows the typical Mendelian inheritance pattern as a dominant gene. In conclusion, the novel sequences of ev21-K locus were a reliable molecular marker for identifying early- and late-feathering chickens across breeds.

Study on Inheritance of Potato virus X Resistance in Capsicum annuum

  • Shi, Jinxia;Choi, Do-Il;Kim, Byung-Dong;Kang, Byoung-Cheorl
    • The Plant Pathology Journal
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    • v.24 no.4
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    • pp.433-438
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    • 2008
  • Potato virus X (PVX) resistance in potato is one of the best-characterized resistance models, however little is known in pepper. To evaluate the resistance to PVX in Capsicum annuum, a total of eleven pepper accessions were used for resistance screening against two PVX strains, USA and UK3. None of them were resistant against strain UK3, whereas four resistant genotypes were found against strain USA, three of which were further characterized. Two unlinked dominant genes were identified for both genotypes Bukang and Perennial; resistance in the genotype CV3 seemed to be conferred by two complementary dominant genes. These results demonstrated that the resistance to PVX in C. annuum is different from that in potato. This is the first report on genetic analysis of PVX resistance in C. annuum.

Variability in Specific Leaf Weight in Mulberry Germplasm and Its Inheritance Pattern

  • Sarkar, A.;Mogili, T.;Chaturvedi, H.K.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.7 no.1
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    • pp.69-73
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    • 2003
  • Specific leaf weight (SLW), defined as the mass of tissue per unit leaf area has been found to be an important physiological parameter as it indicates the relative thickness of leaves. Greater SLW provides more photosynthetic potential per unit area of leaf and hence it is frequently been considered as correlated with photosynthesis in several plant species. Collections of 165 mulberry (Morus sp.) germplasm accessions, both Indian and exotic in origin were evaluated for their variability with respect to SLW. The mean specific leaf weight ranged from 35.3 to $72.3 g/m^{-2}$. The distribution of SLW was found to be normal. High heritability (97.08%) and a small difference between genotypic and phenotypic variance demonstrates the genetic control over SLW. Significant heterotic effect with respect to SLW was observed in crosses when parents with high and low SLW were chosen.

Study on the Inheritance of Powdery Mildew Resistance in Common Wheat (밀의 흰가루병 저항성의 유전에 관한 연구)

  • Young-Am Chae
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.24 no.4
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    • pp.35-37
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    • 1979
  • To investigate the genetic system in resistance to powdery mildew winter wheat cultivar Diplomat which has stable field resistance was crossed with high yielding susceptible winter type Caribo and Hayman's generation mean analysis technique was employed. Mildewing rate on flag-leaf at both heading-flowering and ripe stages were recorded according to lame's quantitative scale. The result indicated that additive gene effect was more important and significant role in the inheritance of resistance while dominant gene effect was minimum, and digenic interations were absent. Narrow sense heritability of resistance at ripe stage was higher than that of heading-flowering stage.

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Clinical genetics of defects in thyroid hormone synthesis

  • Kwak, Min Jung
    • Annals of Pediatric Endocrinology and Metabolism
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    • v.23 no.4
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    • pp.169-175
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    • 2018
  • Thyroid dyshormonogenesis is characterized by impairment in one of the several stages of thyroid hormone synthesis and accounts for 10%-15% of congenital hypothyroidism (CH). Seven genes are known to be associated with thyroid dyshormonogenesis: SLC5A5 (NIS), SCL26A4 (PDS), TG, TPO, DUOX2, DUOXA2, and IYD (DHEAL1). Depending on the underlying mechanism, CH can be permanent or transient. Inheritance is usually autosomal recessive, but there are also cases of autosomal dominant inheritance. In this review, we describe the molecular basis, clinical presentation, and genetic diagnosis of CH due to thyroid dyshormonogenesis, with an emphasis on the benefits of targeted exome sequencing as an updated diagnostic approach.