• Industrial Engineering and Management Systems
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• 제6권1호
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• pp.83-93
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• 2007

This paper gives an attempt to build a decision support tool linked with a simulation software called ARENA for evaluating and comparing the performance of the push and pull material driven strategies operating in the flow shop environment with a bottleneck resource as the shop's constraint. To be fair for such evaluation, the comparison must be made fairly under the optimal setting of both systems' operating parameters. In this study, an optimal-seeking heuristic algorithm, Genetic Algorithm (GA), is employed to suggest a systems' best design based on the economic consideration, which is the profit generated from the system. Results from the study have revealed interesting outcomes, letting us know the strength and weakness of the push and pull mechanisms as well as the effect of each operating parameter to the overall system's financial performance.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2011년도 추계 학술논문 발표대회
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• pp.101-103
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• 2011

Various desired performances of concrete cannot be always obtained by current conventional mix proportion methods for recycled aggregate concrete (RAC). This paper suggests a new design method of mix proportion for RAC to reduce the number of trial mixes using genetic algorithm (GA) which has been an optimization technique to solve the multi-object problem. In mix design method by GA, several fitness functions for the required properties of concrete, i.e., slump, strength, price, and carbonation speed coefficient were considered based on conventional data or fitness function. As a result, various optimum mix proportions for RAC that meet required performances were obtained and the risk evaluation was also conducted for selected mixtures.

• Journal of Genetic Medicine
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• 제5권1호
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• pp.1-6
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• 2008

Knowledge of developmental biology is essential for clinicians who seek to develop a rational approach to the diagnostic evaluation of patients with birth defects. After an accurate diagnosis, a clinician can make predictions about prognosis, recommend management options, and provide an indication of recurrence risk for the parents and relatives. In this paper, we first review the basic mechanisms of embryological development and clinical dysmorphology. We then review cellular and molecular mechanisms in development and related congenital anomalies. Developmental anomalies have a major impact on public health. Genetic counseling and prenatal diagnosis, with the option to continue or to terminate a pregnancy, are important for helping families faced with the risk of a serious congenital anomaly in their offspring. Moreover, primary prevention of birth defects, for example, supplementation of prenatal folic acid and prevention of consumption of alcohol which has teratogenic effects, can be accomplished using developmental biology knowledge.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.1124-1129
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• 2003

In mechanical design, design process is mainly composed of design, explanation and evaluation. In this paper, Using Genetic Algorithms (GA), Evolutionary computation is introduced as new design process. This method promote the efficiency and power of design. Due to the known characteristics of the stage, the approach basically involves a synthetic design method with the composition of building blocks representing the elements of mechanical objects. In order for the building blocks to be more suitable for representation and evolution of mechanical structures, Elementary Cell Blocks (ECBs) are introduced as new building blocks. In this paper, we have demonstrated the implementation of the approach with the design of gear systems.

• 전자공학회논문지B
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• 제32B권7호
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• pp.1025-1035
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• 1995

In this paper, we realize a real time digital FM synthesizer based on genetic algorithm using a general purpose digital signal processor. Especially, we synthesize diverse music sounds nicely using a synthesis model consisting of a single modulator and multiple carriers. Also we present genetic algorithm-based technique which determines optimal parameters for reconstruction through FM synthesis of a sound after analyzing the spectrum of PCM data as a standard music sound using FFT. Using the suggested parameter extractiuon algorithm, we extract parameters of several instruments and then synthesize digital FM sounds. To verify the validity of the parameter extraction algorithm as well as realization of a real time digital music synthesizer, the evaluation is first done by listening the sound directly as subjective test. Secondly, to evaluate the synthesized sound objectively with an engineering sense, we compare the synthesized sound with an original one in a time domain and a frequency domain.

• Molecular & Cellular Toxicology
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• 제3권3호
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• pp.172-176
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• 2007

Butylated hydroxytoluene (BHT) is widely used antioxidant food additives. It has been extensively studied for potential toxicities. BHT appears adverse effects in liver and thyroid. In this study, we evaluated the genetic toxicity of BHT with more advanced methods, in vitro mouse lymphoma assay $tk^{+/-}$ gene assay (MLA) and in vivo mouse supravital micronucleus (MN) assay. BHT did not appear the significantly results in the absence and presence of metabolic activation system with MLA. Also, in vivo testing of BHT yielded negative results with supravital MN assay. These results suggest that BHT itself was not generally considered genotoxic.

• Computers and Concrete
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• 제21권5호
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• pp.505-511
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• 2018

This paper investigates the potential of a hybrid model which combines the least squares support vector machine (LSSVM) and an improved particle swarm optimization (IMPSO) techniques for prediction of concrete compressive strength. A modified PSO algorithm is employed in determining the optimal values of LSSVM parameters to improve the forecasting accuracy. Experimental data on concrete compressive strength in the literature were used to validate and evaluate the performance of the proposed IMPSO-LSSVM model. Further, predictions from five models (the IMPSO-LSSVM, PSO-LSSVM, genetic algorithm (GA) based LSSVM, back propagation (BP) neural network, and a statistical model) were compared with the experimental data. The results show that the proposed IMPSO-LSSVM model is a feasible and efficient tool for predicting the concrete compressive strength with high accuracy.

• 한국정보통신학회논문지
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• 제5권5호
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• pp.877-883
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• 2001

본 논문에서는 유전자 알고리즘을 기반으로 한 새로운 다중사용자 복조기를 제안하고, 최적 (optimum) 다중사용자 복조기와 Hopfield신경망 다중사용자 복조기를 비교 대상으로 하여 원근문제가 존재하는 환경에서 컴퓨터 시뮬레이션을 통해서 비트오율 성능을 비교하였다. 시뮬레이션 결과, 원근문제에 존재하는 채널환경에서는 본 논문에서 제안한 구조는 상당히 적은 계산량으로 최적의 다중사용자 복조기와 Hopfield 다중사용자 복조기와 근접한 성능을 기대할 수 있었고, 원근문제가 존재하지 않는 경우에서는 Hopfield 신경망 구조 보다 우월한 성능향상을 얻을 수 있었다.

• 한국공간구조학회논문집
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• 제15권4호
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• pp.81-89
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• 2015

Damped outrigger systems have been proposed as a novel energy dissipation system to protect tall buildings from severe earthquakes and strong wind loads. In this study, semi-active damping devices such as magnetorheological (MR) dampers instead of passive dampers are installed vertically between the outrigger and perimeter columns to achieve large and adaptable energy dissipation. Control performance of semi-active outrigger damper system mainly depends on the control algorithm. Fuzzy logic control algorithm was used to generate command voltage sent to MR damper. Genetic algorithm was used to optimize the fuzzy logic controller. An artificial earthquake load was generated for numerical simulation. A simplified numerical model of damped outrigger system was developed. Based on numerical analyses, it has been shown that the semi-active damped outrigger system can effectively reduce both displacement and acceleration responses of the tall building in comparison with a passive outrigger damper system.

• Molecular & Cellular Toxicology
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• 제3권2호
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• pp.113-118
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• 2007

Chlorobenzenes due to their acute toxicity and the capability of bioaccumulating are of great health and environmental concern. Especially, 1, 2-dichlorobenzene (CAS No. 95-50-1) is used for organic synthesis, dye manufacture, as a solvent and for other applications in chemical industry. Adverse effects of 1, 2-dichlorobenzene includes increases in liver and kidney weights and hepatotoxicity. In this study, we evaluated the genetic toxicity of 1, 2-dichlorobenzene with more advanced methods, in vitro mouse lymphoma assay $tk^{+/-}$ gene assay (MLA) and in vitro mouse supravital micronucleus (MN) assay. 1, 2-Dichlorobenzene appeared the significantly positive results and the induction of large mutant colonies only in the presence of metabolic activation system with MLA. But in vitro testing of 1, 2-dichlorobenzene yielded negative results with supravital MN assay. These results suggest that 1, 2-dichlorobenzene may play a mutagen rather than clastogen in vitro mammalian system.