• Industrial Engineering and Management Systems
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• v.6 no.1
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• pp.83-93
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• 2007

This paper gives an attempt to build a decision support tool linked with a simulation software called ARENA for evaluating and comparing the performance of the push and pull material driven strategies operating in the flow shop environment with a bottleneck resource as the shop's constraint. To be fair for such evaluation, the comparison must be made fairly under the optimal setting of both systems' operating parameters. In this study, an optimal-seeking heuristic algorithm, Genetic Algorithm (GA), is employed to suggest a systems' best design based on the economic consideration, which is the profit generated from the system. Results from the study have revealed interesting outcomes, letting us know the strength and weakness of the push and pull mechanisms as well as the effect of each operating parameter to the overall system's financial performance.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2011.11a
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• pp.101-103
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• 2011

Various desired performances of concrete cannot be always obtained by current conventional mix proportion methods for recycled aggregate concrete (RAC). This paper suggests a new design method of mix proportion for RAC to reduce the number of trial mixes using genetic algorithm (GA) which has been an optimization technique to solve the multi-object problem. In mix design method by GA, several fitness functions for the required properties of concrete, i.e., slump, strength, price, and carbonation speed coefficient were considered based on conventional data or fitness function. As a result, various optimum mix proportions for RAC that meet required performances were obtained and the risk evaluation was also conducted for selected mixtures.

• Journal of Genetic Medicine
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• v.5 no.1
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• pp.1-6
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• 2008

Knowledge of developmental biology is essential for clinicians who seek to develop a rational approach to the diagnostic evaluation of patients with birth defects. After an accurate diagnosis, a clinician can make predictions about prognosis, recommend management options, and provide an indication of recurrence risk for the parents and relatives. In this paper, we first review the basic mechanisms of embryological development and clinical dysmorphology. We then review cellular and molecular mechanisms in development and related congenital anomalies. Developmental anomalies have a major impact on public health. Genetic counseling and prenatal diagnosis, with the option to continue or to terminate a pregnancy, are important for helping families faced with the risk of a serious congenital anomaly in their offspring. Moreover, primary prevention of birth defects, for example, supplementation of prenatal folic acid and prevention of consumption of alcohol which has teratogenic effects, can be accomplished using developmental biology knowledge.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1124-1129
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• 2003

In mechanical design, design process is mainly composed of design, explanation and evaluation. In this paper, Using Genetic Algorithms (GA), Evolutionary computation is introduced as new design process. This method promote the efficiency and power of design. Due to the known characteristics of the stage, the approach basically involves a synthetic design method with the composition of building blocks representing the elements of mechanical objects. In order for the building blocks to be more suitable for representation and evolution of mechanical structures, Elementary Cell Blocks (ECBs) are introduced as new building blocks. In this paper, we have demonstrated the implementation of the approach with the design of gear systems.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.32B no.7
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• pp.1025-1035
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• 1995

In this paper, we realize a real time digital FM synthesizer based on genetic algorithm using a general purpose digital signal processor. Especially, we synthesize diverse music sounds nicely using a synthesis model consisting of a single modulator and multiple carriers. Also we present genetic algorithm-based technique which determines optimal parameters for reconstruction through FM synthesis of a sound after analyzing the spectrum of PCM data as a standard music sound using FFT. Using the suggested parameter extractiuon algorithm, we extract parameters of several instruments and then synthesize digital FM sounds. To verify the validity of the parameter extraction algorithm as well as realization of a real time digital music synthesizer, the evaluation is first done by listening the sound directly as subjective test. Secondly, to evaluate the synthesized sound objectively with an engineering sense, we compare the synthesized sound with an original one in a time domain and a frequency domain.

• Molecular & Cellular Toxicology
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• v.3 no.3
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• pp.172-176
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• 2007

Butylated hydroxytoluene (BHT) is widely used antioxidant food additives. It has been extensively studied for potential toxicities. BHT appears adverse effects in liver and thyroid. In this study, we evaluated the genetic toxicity of BHT with more advanced methods, in vitro mouse lymphoma assay $tk^{+/-}$ gene assay (MLA) and in vivo mouse supravital micronucleus (MN) assay. BHT did not appear the significantly results in the absence and presence of metabolic activation system with MLA. Also, in vivo testing of BHT yielded negative results with supravital MN assay. These results suggest that BHT itself was not generally considered genotoxic.

• Computers and Concrete
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• v.21 no.5
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• pp.505-511
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• 2018

This paper investigates the potential of a hybrid model which combines the least squares support vector machine (LSSVM) and an improved particle swarm optimization (IMPSO) techniques for prediction of concrete compressive strength. A modified PSO algorithm is employed in determining the optimal values of LSSVM parameters to improve the forecasting accuracy. Experimental data on concrete compressive strength in the literature were used to validate and evaluate the performance of the proposed IMPSO-LSSVM model. Further, predictions from five models (the IMPSO-LSSVM, PSO-LSSVM, genetic algorithm (GA) based LSSVM, back propagation (BP) neural network, and a statistical model) were compared with the experimental data. The results show that the proposed IMPSO-LSSVM model is a feasible and efficient tool for predicting the concrete compressive strength with high accuracy.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.5 no.5
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• pp.877-883
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• 2001

In this paper, we propose a new Genetic Algorithm(GA)-based Multiuser Detector(MUD), and its performance is evaluated by computer simulation compared to both the optimum MUD and the Hopfield neural network(NN) -based MUD when the near-far problem exists. From the results of comprehensive simulation, it is shown that the proposed MUD in this paper can guarantee a close BER performance compared to both the optimum MUD and the Hopfield NN MUD with a considerable reduced complexity under the near-far condition. Furthermore, a more performance improvement than the Hopfield W MUD can be expected when the near-far problem does not exist.

• Journal of Korean Association for Spatial Structures
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• v.15 no.4
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• pp.81-89
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• 2015

Damped outrigger systems have been proposed as a novel energy dissipation system to protect tall buildings from severe earthquakes and strong wind loads. In this study, semi-active damping devices such as magnetorheological (MR) dampers instead of passive dampers are installed vertically between the outrigger and perimeter columns to achieve large and adaptable energy dissipation. Control performance of semi-active outrigger damper system mainly depends on the control algorithm. Fuzzy logic control algorithm was used to generate command voltage sent to MR damper. Genetic algorithm was used to optimize the fuzzy logic controller. An artificial earthquake load was generated for numerical simulation. A simplified numerical model of damped outrigger system was developed. Based on numerical analyses, it has been shown that the semi-active damped outrigger system can effectively reduce both displacement and acceleration responses of the tall building in comparison with a passive outrigger damper system.

• Molecular & Cellular Toxicology
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• v.3 no.2
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• pp.113-118
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• 2007

Chlorobenzenes due to their acute toxicity and the capability of bioaccumulating are of great health and environmental concern. Especially, 1, 2-dichlorobenzene (CAS No. 95-50-1) is used for organic synthesis, dye manufacture, as a solvent and for other applications in chemical industry. Adverse effects of 1, 2-dichlorobenzene includes increases in liver and kidney weights and hepatotoxicity. In this study, we evaluated the genetic toxicity of 1, 2-dichlorobenzene with more advanced methods, in vitro mouse lymphoma assay $tk^{+/-}$ gene assay (MLA) and in vitro mouse supravital micronucleus (MN) assay. 1, 2-Dichlorobenzene appeared the significantly positive results and the induction of large mutant colonies only in the presence of metabolic activation system with MLA. But in vitro testing of 1, 2-dichlorobenzene yielded negative results with supravital MN assay. These results suggest that 1, 2-dichlorobenzene may play a mutagen rather than clastogen in vitro mammalian system.