• Title/Summary/Keyword: Genetic components

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Influence of Inbreeding Depression on Genetic (Co)Variance and Sire-by-Year Interaction Variance Estimates for Weaning Weight Direct-Maternal Genetic Evaluation

  • Lee, C.;Pollak, E.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.5
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    • pp.510-513
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    • 1997
  • This study examined the effects of ignoring inbreeding depression on (co)variance components for weaning weight through the use of Monte Carlo simulation. Weaning weight is of particular interest as a trait for which additive direct and maternal genetic components exist and there then is the potential for a direct-maternal genetic covariance. Ignoring inbreeding depression in the analytical model (.8 kg reduction of phenotypic value per 1% inbreeding) led to biased estimates of all genetic (co) variance components, all estimates being larger than the true values of the parameters. In particular, a negative bias in the direct-maternal genetic covariance was observed in analyses that ignored inbreeding depression. A small spurious sire-by-year interaction variance was also observed.

A double-labeling marker-based method for estimating inbreeding and parental genomic components in a population under conservation

  • Li, Wenting;Zhang, Mengmeng;Wang, Kejun;Lu, Yunfeng;Tang, Hui;Wu, Keliang
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.1
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    • pp.12-23
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    • 2020
  • Objective: The objective of a conservation program is to maintain maximum genetic diversity and preserve the viability of a breed. However, the efficiency of a program is influenced by the ability to accurately measure and predict genetic diversity. Methods: To examine this question, we conducted a simulation in which common measures (i.e. heterozygosity) and novel measures (identity-by-descent probabilities and parental genomic components) were used to estimate genetic diversity within a conserved population using double-labeled single nucleotide polymorphism markers. Results: The results showed that the accuracy and sensitivity of identity-by-state probabilities and heterozygosity were close to identity by descent (IBD) probabilities, which reflect the true genetic diversity. Expected heterozygosity most closely aligned with IBD. All common measures suggested that practices used in the current Chinese pig conservation program result in a ~5% loss in genetic diversity every 10 generations. Parental genomic components were also analyzed to monitor real-time changes in genomic components for each male and female ancestor. The analysis showed that ~7.5% of male families and ~30% of female families were lost every 5 generations. After 50 generations of simulated conservation, 4 male families lost ~50% of their initial genomic components, and the genomic components for 24.8% of the female families were lost entirely. Conclusion: In summary, compared with the true genetic diversity value obtained using double-labeled markers, expected heterozygosity appears to be the optimal indicator. Parental genomic components analysis provides a more detailed picture of genetic diversity and can be used to guide conservation management practices.

A Efficient Controller Design with Fuzzy Logic and Genetic Algorithms (퍼지 로직과 유전자 알고리즘을 이용한 효율적인 제어기 설계)

  • 장원빈;김동일;권기호
    • Proceedings of the IEEK Conference
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    • 2000.06e
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    • pp.55-58
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    • 2000
  • Previous works using a Multi-population Genetic Algorithm have divided chromosome into two components, rule sets and membership functions. However, in this case bad rule sets disturb optimization in good rule sets and membership functions. A new method for a Multi-population Genetic Algorithm suggests three components, good rule sets, bad rule sets, and membership functions. To show the effectiveness of this method, fuzzy controller is applied in a Truck Backing Problem. Results of the computer simulation show good adaptation of the proposed method for a Multi-population Genetic Algorithm.

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A survey of the genetic components introduced into approved GM crops (국내외 상업화 GM 작물의 유전요소 분석)

  • Woo, Hee-Jong;Chung, Chan-Mi;Shin, Kong-Sik;Ji, Hyeon-So;Lee, Ki-Jong;Suh, Seok-Chul;Kweon, Soon-Jong;Cho, Yong-Gu
    • Journal of Plant Biotechnology
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    • v.36 no.2
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    • pp.106-114
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    • 2009
  • Genetic components introduced into approved GM crops are a key subject for safety assessment and provide a basis for the development of detection methods for GM crops. In order to understand the genetic components in approved GM crops comprehensively, we screened the genetic vector maps of GM crops that had been approved for commercialization around the world. A total of 64 varieties from 5 major GM crop species (maize, canola, cotton, soybean, and tomato) were subjected to analysis. The genetic components included genes, promoters, terminators, and selection marker. This survey may be useful for researchers who develop GM crops and methods for detecting GM crops.

Estimation of the Heritabilities and Genetic Correlations on Body Shape Components in Korean Native Chicken (한국재래계의 체형에 대한 유전력 및 유전상관의 추정)

  • 한성욱;상병찬;이준현;정욱수;상병돈
    • Korean Journal of Poultry Science
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    • v.25 no.1
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    • pp.1-9
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    • 1998
  • This study was carried out to get the basic and applicable data for breeding plan and selection in order to improve the body shape components in Korean native chicken. The hentabilities and genetic correlations on body shape components were estimated by sire, dam and combined components of variance. Data analyzed were records of 1,096 progenies produced from 180 dams and 26 sires from April, 1994 to September, 1995. On body shape components at 4, 8 and 16 weeks of age, the shank lengths were 55.63, 82.94 and 103.8Omm: breast girths were 15.087, 21.069, and 26.137mm: breast widths were 40.910, 54.575 and 73.088mm, respectively. The estimates of hentabilities of body shape components based on the variance of sires, dams, and combined components at 4, 8 and 16 weeks of age were O.O65~O.197, O.25O~O.794 and O.185~O.495 for shank length: O.123~O. 215, O.033~O.513 and 0.063~0.257 for breast girth; 0.024~0.158, 0.118~0.410 and 0.111~0.222 for breast width, respectively. The coefficients of genetic correlations among the body shape components at 4 weeks of age were 0.565, 0.725 and 0.678 for breast girth with breast width, shank length and tibia length : 0.690 and 0.804 for breast width with shank length and tibia length; 0.972 between shank length and tibia length.

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Genetic parameters and principal components analysis of breeding value for birth and weaning weight in Egyptian buffalo

  • Salem, Mohamed Mahmoud Ibrahim;Amin, Amin Mohamed Said;Ashour, Ayman Fouad;Ibrahim, Mohamed Mohamed El-said;Abo-Ismail, Mohammed Kotb
    • Animal Bioscience
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    • v.34 no.1
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    • pp.12-19
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    • 2021
  • Objective: The objectives of the current study were to study the main environmental factors affecting birth weight (BW) and weaning weight (WW), estimate variance components, genetic parameters and genetic trend and to evaluate the variability and relationships among breeding value of BW and WW using principal components analysis (PCA). Methods: A total of 16,370 records were collected from 8,271 buffalo calves. Genetic parameters and breeding values were estimated using a bivariate animal model which includes direct, maternal and permanent maternal effects. These estimates were standardized and used in PCA. Results: The direct heritability estimates were 0.06 and 0.41 for BW and WW, respectively whereas direct maternal heritability values were 0.03 and 0.14, respectively. Proportions of variance due to permanent environmental effects of dam were 0.455 and 0.280 for BW and WW respectively. The genetic correlation between BW and WWs was weak approaching zero, but the maternal correlation was 0.26. The first two principal components (PC1 and PC2) were estimated utilizing the standardized breeding values according to Kaiser method. The total variance explained by the first two PCs was 71.17% in which 45.91% and 25.25% were explained by PC1 and PC2, respectively. The direct breeding values of BW were related to PC2 but those of WW and maternal breeding values of BW and WWs were associated with PC1. Conclusion: The results of genetic parameters and PCA indicate that BW and WWs were not genetically correlated and improving growth traits of Egyptian buffaloes could be achieved using WW without any adverse effect by BW.

Variance components estimation for farrowing traits of three purebred pigs in Korea

  • Lopez, Bryan Irvine;Kim, Tae Hun;Makumbe, Milton Tinashe;Song, Chol Won;Seo, Kang Seok
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.9
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    • pp.1239-1244
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    • 2017
  • Objective: This study was conducted to estimate breed-specific variance components for total number born (TNB), number born alive (NBA) and mortality rate from birth through weaning including stillbirths (MORT) of three main swine breeds in Korea. In addition, the importance of including maternal genetic and service sire effects in estimation models was evaluated. Methods: Records of farrowing traits from 6,412 Duroc, 18,020 Landrace, and 54,254 Yorkshire sows collected from January 2001 to September 2016 from different farms in Korea were used in the analysis. Animal models and the restricted maximum likelihood method were used to estimate variances in animal genetic, permanent environmental, maternal genetic, service sire and residuals. Results: The heritability estimates ranged from 0.072 to 0.102, 0.090 to 0.099, and 0.109 to 0.121 for TNB; 0.087 to 0.110, 0.088 to 0.100, and 0.099 to 0.107 for NBA; and 0.027 to 0.031, 0.050 to 0.053, and 0.073 to 0.081 for MORT in the Duroc, Landrace and Yorkshire breeds, respectively. The proportion of the total variation due to permanent environmental effects, maternal genetic effects, and service sire effects ranged from 0.042 to 0.088, 0.001 to 0.031, and 0.001 to 0.021, respectively. Spearman rank correlations among models ranged from 0.98 to 0.99, demonstrating that the maternal genetic and service sire effects have small effects on the precision of the breeding value. Conclusion: Models that include additive genetic and permanent environmental effects are suitable for farrowing traits in Duroc, Landrace, and Yorkshire populations in Korea. This breed-specific variance components estimates for litter traits can be utilized for pig improvement programs in Korea.

Development of an User Interface Design Method using Adaptive Genetic Algorithm (적응형 유전알고리즘을 이용한 사용자 인터페이스 설계 방법 개발)

  • Jung, Ki-Hyo
    • Journal of Korean Institute of Industrial Engineers
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    • v.38 no.3
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    • pp.173-181
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    • 2012
  • The size and layout of user interface components need to be optimally designed in terms of reachability, visibility, clearance, and compatibility in order for efficient and effective use of products. The present study develops an ergonomic design method which optimizes the size and layout of user interface components using adaptive genetic algorithm. The developed design method determines a near-optimal design which maximizes the aggregated score of 4 ergonomic design criteria (reachability, visibility, clearance, and compatibility). The adaptive genetic algorithm used in the present study finds a near-optimum by automatically adjusting the key parameter (probability of mutation) of traditional genetic algorithm according to the characteristic of current solutions. Since the adaptive mechanism partially helps to overcome the local optimality problem, the probability of finding the near-optimum has been substantially improved. To evaluate the effectiveness of the developed design method, the present study applied it to the user interface design for a portable wireless communication radio.

Genetic Diversity of Soybean Pod Shape Based on Elliptic Fourier Descriptors

  • Truong Ngon T.;Gwag Jae-Gyun;Park Yong-Jin;Lee Suk-Ha
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.50 no.1
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    • pp.60-66
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    • 2005
  • Pod shape of twenty soybean (Glycine max L. Merrill) genotypes was evaluated quantitatively by image analysis using elliptic Fourier descriptors and their principal components. The closed contour of each pod projection was extracted, and 80 elliptic Fourier coefficients were calculated for each contour. The Fourier coefficients were standardized so that they were invariant of size, rotation, shift, and chain code starting point. Then, the principal components on the standardized Fourier coefficients were evaluated. The cumulative contribution at the fifth principal component was higher than $95\%$, indicating that the first, second, third, fourth, and fifth principal components represented the aspect ratio of the pod, the location of the pod centroid, the sharpness of the two pod tips and the roundness of the base in the pod contour, respectively. Analysis of variance revealed significant genotypic differences in these principal components and seed number per pod. As the principal components for pod shape varied continuously, pod shape might be controlled by polygenes. It was concluded that principal component scores based on elliptic Fourier descriptors yield seemed to be useful in quantitative parameters not only for evaluating soybean pod shape in a soybean breeding program but also for describing pod shape for evaluating soybean germplasm.

A Maintenance Design of Connected-(r,s)-out-of-(m,n):F System Using Genetic Algorithm (유전자 알고리듬을 이용한(m,n)중-연속(r,s):고장 격자 시스템의 정비 모형)

  • Yun, Won-Young;Kim, Gui-Rae;Jeong, Cheol-Hun
    • Journal of Korean Institute of Industrial Engineers
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    • v.30 no.3
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    • pp.250-260
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    • 2004
  • This study considers a linear connected-(r,s)-out-of-(m,n):F lattice system whose components are ordered like the elements of a linear (m,n )-matrix. We assume that all components are in the state 1 (operating) or 0 (failed) and identical and s-independent. The system fails whenever at least one connected (r,s)-submatrix of failed components occurs. The purpose of this paper is to present an optimization scheme that aims at minimizing the expected cost per unit time. To find the optimal threshold of maintenance intervention, we use a genetic algorithm for the cost optimization procedure. The expected cost per unit time is obtained by Monte Carlo simulation. The sensitivity analysis to the different cost parameters has also been made.