• 제목/요약/키워드: Genetic Factors

검색결과 1,658건 처리시간 0.032초

다목적 유전자 알고리즘을 이용한 상수관망에서 스프링 서지 완화 밸브의 최적화 (Optimum design of direct spring loaded pressure relief valve in water distribution system using multi-objective genetic algorithm)

  • 김현준;백다원;김상현
    • 상하수도학회지
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    • 제32권2호
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    • pp.115-122
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    • 2018
  • Direct spring loaded pressure relief valve(DSLPRV) is a safety valve to relax surge pressure of the pipeline system. DSLPRV is one of widely used safety valves for its simplicity and efficiency. However, instability of the DSLPRV can caused by various reasons such as insufficient valve volume, natural vibration of the spring, etc. In order to improve reliability of DSLPRV, proper selection of design factors of DSLPRV is important. In this study, methodology for selecting design factors for DSLPRV was proposed. Dynamics of the DSLPRV disk was integrated into conventional 1D surge pressure analysis. Multi-objective genetic algorithm was also used to search optimum design factors for DSLPRV.

HVDC 시스템을 위한 진화론적으로 최적화된 자기 동조 퍼지제어기 (Genetically optimized self-tuning Fuzzy-PI controller for HVDC system)

  • 왕중선;양정제;안태천
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2006년도 심포지엄 논문집 정보 및 제어부문
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    • pp.279-281
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    • 2006
  • In this paper, we study an approach to design a self-tuning Fuzzy-PI controller in HVDC(High Voltage Direct Current) system. In the rectifier of conversional HVDC system, turning on, turning off, triggering and protections of thyristors have lots of problems that can make the dynamic instability and cannot damp the dynamic disturbance efficiently. The above problems are solved by adapting Fuzzy-PI controller for the fire angle control of rectifier.[7] The performance of the Fuzzy-PI controller is sensitive to the variety of scaling factors. The design procedure dwells on the use of evolutionary computing(Genetic Algorithms, GAs). Then we can obtain the optimal scaling factors of the Fuzzy-PI controller by Genetic Algorithms. In order to improve Fuzzy-PI controller, we adopt FIS to tune the scaling factors of the Fuzzy-PI controller on line. A comparative study has been performed between Fuzzy-PI and self-tuning Fuzzy-PI controller, to prove the superiority of the proposed scheme.

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The Effects of Genetic and Nutritional Factors on Pork Quality - Review -

  • Ellis, M.;McKeith, F.K.;Miller, K.D.
    • Asian-Australasian Journal of Animal Sciences
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    • 제12권2호
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    • pp.261-270
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    • 1999
  • Consumers are increasingly quality orientated and an understanding of the factors that influence product quality is a prerequisite to the development of programs to produce quality pork to meet market requirements. Pork quality is comprised of many components and is multi-factorial in nature. This review focuses on genetic and environmental influences on muscle color, water holding capacity, and palatability attributes. The impact of genetic factors such as breed variation and the influence of major genes (the Halothane and Rendement Napole genes), as well as relationships between carcass leanness and quality, are considered. In addition, the effect of nutrition, including vitamins and minerals, feeding level, and dietary energy:protein ratio, on pork quality is reviewed. Finally, the impact of diet on fat composition and quality is summarized.

Cardiomyopathies in children

  • Hong, Young Mi
    • Clinical and Experimental Pediatrics
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    • 제56권2호
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    • pp.52-59
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    • 2013
  • Cardiomyopathy (CMP) is a heterogeneous disease caused by a functional abnormality of the cardiac muscle. CMP is of 2 major types, dilated and hypertrophic, and is further classified as either primary or secondary. Secondary CMP is caused by extrinsic factors, including infection, ischemia, hypertension, and metabolic disorders. Primary CMP is diagnosed when the extrinsic factors of secondary CMP are absent. Furthermore, the World Health Organization, American Heart Association, and European Cardiology Association have different systems for clinically classifying primary CMP. Primary CMP is rare and associated with a family history of the disease, implying that genetic factors might affect its incidence. In addition, the incidence of CMP varies widely according to patient ethnicity. Genetic testing plays an important role in the care of patients with CMP and their families because it confirms diagnosis, determines the appropriate care for the patient, and possibly affects patient prognosis. The diagnosis and genetic identification of CMP in patients' families allow the possibility to identify novel genes that may lead to new treatments. This review focuses on the epidemiology, pathophysiology, diagnosis, and treatment of CMP, with the aim of providing pediatricians with insights that may be helpful in the early identification and management of idiopathic CMP in children.

Characterization of Single Nucleotide Polymorphisms in 55 Disease-Associated Genes in a Korean Population

  • Lee, Seung-Ku;Kim, Hyoun-Geun;Kang, Jason-J.;Oh, Won-Il;Oh, Berm-Seok;Kwack, Kyu-Bum
    • Genomics & Informatics
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    • 제5권4호
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    • pp.152-160
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    • 2007
  • Most common diseases are caused by multiple genetic and environmental factors. Among the genetic factors, single nucleotide polymorphisms (SNPs) are common DNA sequence variations in individuals and can serve as important genetic markers. Recently, investigations of gene-based and whole genome-based SNPs have been applied to association studies for marker discovery. However, SNPs are so population-specific that the association needs to be verified. Fifty-five genes and 384 SNPs were selected based on association with disease. Genotypes of 337 SNPs in candidate genes were determined using Illumina Sentrix Array Matrix (SAM) chips by an allele-specific extension method in 364 unrelated Korean individuals. Allelic frequencies of SNPs were compared with those of other populations obtained from the International HapMap database. Minor allele frequencies, linkage disequilibrium blocks, tagSNPs, and haplotypes of functional candidate SNPs in 55 genetic disease-associated genes were provided. Our data may provide useful information for the selection of genetic markers for gene-based genetic disease-association studies of the Korean population.

소아청소년 우울증에서의 환경적 위험 인자들과 임상적 의미 (Environmental Risk Factors for Children and Adolescents Suffering from Depressive Disorder : Clinical Aspects)

  • 이문수
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제21권3호
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    • pp.141-146
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    • 2010
  • This summary of literature during the past year reviews published studies relating to risk factors for depressive disorders in children and adolescents. Risk factors include environmental toxins, socio-environmental, and genetic factors. As depression has a complex, multifactorial causal mechanism, it is likely that the accumulation and/ or interaction among multiple risk factors lead to depression. Findings related to the result of toxin exposure have been difficult to interpret given that risk factors tend to interact and that higher mental functions are not easily measurable. However, some findings have been consistent. Clinical research data has also shown that the risk for negative outcomes may be modified both by genetic and environmental factors through a gene environment interplay mechanism.

Using Genetic Algorithms to Support Artificial Neural Networks for the Prediction of the Korea stock Price Index

  • Kim, Kyoung-jae;Ingoo han
    • 한국지능정보시스템학회:학술대회논문집
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    • 한국지능정보시스템학회 2000년도 춘계정기학술대회 e-Business를 위한 지능형 정보기술 / 한국지능정보시스템학회
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    • pp.347-356
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    • 2000
  • This paper compares four models of artificial neural networks (ANN) supported by genetic algorithms the prediction of stock price index. Previous research proposed many hybrid models of ANN and genetic algorithms(GA) in order to train the network, to select the feature subsets, and to optimize the network topologies. Most these studies, however, only used GA to improve a part of architectural factors of ANN. In this paper, GA simultaneously optimized multiple factors of ANN. Experimental results show that GA approach to simultaneous optimization for ANN (SOGANN3) outperforms the other approaches.

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A Genetic Analysis of the Common Squid, Todarodes pacificus in the Korean Waters

  • Kim, Yeong-Hye;Kang, Yong-Joo;Park, Jung-Youn
    • 한국패류학회지
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    • 제18권1호
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    • pp.9-14
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    • 2002
  • In order to estimate the genetic variability and differentiation in common squid, eleven isozymic loci, coded for nine enzymes detected by starch gel electrophoresis, were scored from nine spawning cohorts in four localities. The expected average heterozygosity ranged from 0.00019 (between II-S$_2$ and Na-W) to 0.00814 (Between Bu-S and Na-W) in nine different spawning cohorts in four localities. A dendrogram, based on genetic distance mentioned, illustrated that nine different spawning cohorts were divided into three groups, similar to the result estimated by their ecological characterizations. From these results, we estimate that the common squid distributed throughout Korean waters will maintain this gene exchange. It is postulated that either the summer or the autumn spawning cohort has developed a local population that is isolated by hydrographic factors.

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The Sca I RFLP of Atrial Natriuretic Peptide Gene in Koreans

  • Kang, Byung-Yong;Bae, Joon-Seol;Kim, Ki-Tae;Lee, Kang-Oh
    • 한국환경독성학회:학술대회논문집
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    • 한국환경독성학회 2002년도 추계국제학술대회
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    • pp.165-165
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    • 2002
  • Hypertension is considered to be caused by a complicated combination of genetic and environmental factors. Atrial natriuretic peptide (ANP) has been to suppress renin activity and inhibit the synthesis and release of aldosterone. Therefore, Abnormalities of this peptide caused by genetic variation may be influence the blood pressure. The aim of present study was to examine the relationship between hypertension and Sca I RFLP of ANP gene in Korean population. The genotype distribution of this RFLP was significantly different between normotensives and hypertensives (P<0.05). However, this genetic marker was not significantly associated with any anthropometric parameters or plasma lipid concentrations in our study group. Therefore, our result suggest that Sca I RFLP of ANP gene may be useful as genetic marker in the ethiology of hypertension in Korean population, independent of any cardiovascular risk. factors studied.

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