• Clinical and Experimental Reproductive Medicine
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• v.37 no.3
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• pp.261-266
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• 2010

Diagnosis of heterotopic pregnancy could be delayed because of insufficient clinical symptoms. Many clinician mistook the symptoms associated with ectopic pregnancy for the symptoms of complicated normal intrauterine pregnancy. The incidence of heterotopic pregnancies has been increased because of the use of various ovulation induction and assisted reproductive technologies. We experienced a case of bilateral tubal pregnancies and intrauterine twin pregnancy in polycystic ovary syndrome woman conceived after ovulation induction by clomiphene citrate. We report this case with a brief review of the literatures.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.1
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• pp.1-7
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• 2015

Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In this study, we explored the regulatory effects of berberine on Toll-like receptors during the intestinal mucosal damaging process in rats. Male Sprague-Dawlay (SD) rats were treated with berberine for 5 d before undergoing cecal ligation and puncture (CLP) to induce polymicrobial sepsis. The expression of Toll-like receptor 2 (TLR 2), TLR 4, TLR 9, the activity of nuclear factor-kappa B ($NF-{\kappa}B$), the levels of selected cytokines and chemokines, percentage of cell death in intestinal epithelial cells, and mucosal permeability were investigated at 0, 2, 6, 12 and 24 h after CLP. Results showed that the tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and interleukin-6 (IL-6) level were significantly lower in berberine-treated rats compared to the control animals. Conversely, the expression level of tight junction proteins, percentage of cell death in intestinal epithelial cells and the mucosal permeability were significantly higher in berberine-treated rats. The mRNA expression of TLR 2, TLR 4, and TLR 9 were significantly affected by berberine treatment. Our results indicate that pretreatment with berberine attenuates tissue injury and protects the intestinal mucosal barrier in early phase of sepsis and this may possibly have been mediated through the TLRs pathway.

• Journal of Gastric Cancer
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• v.22 no.3
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• pp.220-234
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• 2022

Purpose: The incidence of adenocarcinoma of the esophagogastric junction (AEG) has increased in recent years, and the optimal surgical strategy for AEG remains highly controversial. We aimed to evaluate the safety and efficacy of proximal gastrectomy with double-tract reconstruction (PG-DT) for the treatment of patients with AEG. Materials and Methods: We retrospectively analyzed patients with Siewert type II/III AEG between January 2013 and July 2018. Clinicopathological characteristics, survival, surgical outcomes, quality of life (QOL), and nutritional status were compared between the PG-DT and total gastrectomy with Roux-en-Y anastomosis (TG-RY) groups. Results: After propensity score matching, 33 patients in each group were analyzed. There were no statistical differences between the 2 groups in terms of disease-free survival and overall survival. The surgical option was not an independent prognostic factor based on the multivariate analysis. In addition, no differences were found in terms of surgical complications. There were no significant differences in QOL assessed by the Visick grade, Gastrointestinal Symptom Rating Scale, or endoscopic findings. Furthermore, the long-term nutritional advantage of the PG-DT group was significantly greater than that of the TG-RY group. Conclusions: PG-DT is a safe and effective procedure for patients with local Siewert type II/III AEG, regardless of the TNM stage.

• Geomechanics and Engineering
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• v.37 no.1
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• pp.9-19
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• 2024

This study presents an energy analysis for large-strain cavity expansion problem based on the general strength criterion and energy theory. This study focuses on the energy dissipation problem during the cavity expansion process, dividing the soil mass around the cavity into an elastic region and a plastic region. Assuming compliance with the small deformation theory in the elastic region and the large deformation theory in the plastic region, combined with the general strength criterion of soil mass and energy theory, the energy dissipation solution for cavity expansion problem is derived. Firstly, from an energy perspective, the process of cavity expansion in soil mass is described as an energy conversion process. The energy dissipation mechanism is introduced into the traditional analysis of cavity expansion, and a general analytical solution for cavity expansion related to energy is derived. Subsequently, based on this general analytical solution of cavity expansion, the influence of different strength criterion, large-strain, expansion radius, cavity shape and characteristics of soil mass on the stress distribution, displacement field and energy evolution around the cavity is studied. Finally, the effectiveness and reliability of theoretical solution is verified by comparing the results of typical pressure-expansion curves with existing literature algorithms. The results indicate that different strength criterion have a relatively small impact on the displacement and strain field around the cavity, but a significant impact on the stress distribution and energy evolution around the cavity.

• Honam Mathematical Journal
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• v.34 no.3
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• pp.381-390
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• 2012

In this paper, we give some characterizations for a quaternionic general helix by means of curvatures of a curve in a 4-dimensional Euclidean space.

• Archives of Plastic Surgery
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• v.42 no.2
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• pp.240-241
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• 2015

• Bulletin of the Korean Mathematical Society
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• v.50 no.6
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• pp.2071-2077
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• 2013

In this paper we consider the existence of smooth conics on a general hypersurface of degree d in $\mathbb{P}^n$.

• Proceedings of the Materials Research Society of Korea Conference
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• 1998.08a
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• pp.61.1-61
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• 1998

• East Asian mathematical journal
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• v.35 no.3
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• pp.331-340
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• 2019

In this paper, we investigate the stability for the functional equation $f(x+ky)-kf(x+y)+kf(x-y)-f(x-ky)-(k^3-k)f(y)+(k^3-k)f(-y)=0$ in the sense of M. S. Moslehian and Th. M. Rassias.

• Bulletin of the Korean Mathematical Society
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• v.54 no.2
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• pp.399-416
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• 2017

In this paper, we study a class of Finsler metrics called general (${\alpha},{\beta}$)-metrics, which are defined by a Riemannian metric ${\alpha}$ and a 1-form ${\beta}$. We show that every general (${\alpha},{\beta}$)-metric with isotropic Berwald curvature is either a Berwald metric or a Randers metric. Moreover, a lot of new isotropic Berwald general (${\alpha},{\beta}$)-metrics are constructed explicitly.