• 대한치과마취과학회지
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• 제13권4호
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• pp.179-188
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• 2013

Background: Today, there are computer controlled local anesthesia devices used clinically. The main principle is to control injection speed by computer aided system, and it relieves pain. However, there are few objective data considering this subject. In this literature review, we researched studies about computer controlled anesthetic delivery. We compared pain control effect of computer controlled to conventional local anesthetic syringe system. Methods: A bibliographic search in PubMed was performed and we reviewed original articles. Results: There were 18 publications that compared pain control effect of computer controlled to conventional system. There were 8 articles reported of children, similar pain control effect was found in 7 of them. One study showed superior pain control effect of computer controlled anesthetic delivery. For adults, 10 studies showed superior pain control effect in computer aided system. Conclusions: Computer controlled anesthetic delivery has similar or superior pain control effect compared to conventional local anesthetic syringe system. For both children and adults, computer controlled anesthetic delivery could be clinically useful, still it may be more effective for adults.

• Journal of Dental Anesthesia and Pain Medicine
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• 제16권3호
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• pp.203-208
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• 2016

Background: In South Korea, the number of cases of dental treatment for the disabled is gradually increasing, primarily at regional dental clinics for the disabled. This study investigated pediatric patients at a treatment clinic for the disabled within a university hospital who received dental treatment under general anesthesia. This data could assist those that provide dental treatment for the disabled and guide future treatment directions and new policies. Methods: This study was a retrospective analysis of 263 cases in which patients received dental treatment under general anesthesia from January 2011 to May 2016. The variables examined were gender, age, reason for anesthesia, type of disability, time under anesthesia, duration of treatment, type of procedure, treatment details, and annual trends in the use of general anesthesia. Results: Among pediatric patients with disabilities who received dental treatment under general anesthesia, the most prevalent age group was 5-8 years old (124 patients, 47.1%), and the primary reason for administering anesthesia was dental anxiety or phobia. The mean time under anesthesia was $132.7{\pm}77.6min$, and the mean duration of treatment was $101.9{\pm}71.2min$. The most common type of treatment was restoration, accounting for 158 of the 380 treatments performed. Conclusions: Due to increasing demand, the number of cases of dental treatment performed under general anesthesia is expected to continue increasing, and it can be a useful method of treatment in patients with dental anxiety or phobia.

• 문화기술의 융합
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• 제7권2호
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• pp.185-190
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• 2021

본 연구는 성인대학생과 일반대학생의 물질주의 가치관 및 대인관계의 상관관계를 알아보고 두 집단을 비교하고자 하였다. 이를 위해 전국에 재학 중인 성인대학생 228명, 일반대학생 216명을 대상으로 SPSS Statistics 25.0 프로그램을 이용하여 분석하였다. 첫째, 성인대학생과 일반대학생의 일반적 특성에 따른 물질주의 가치관의 차이를 알아본 결과, 성별, 종교, 학교형태, 학년, 한 달 월급(용돈), 한 달 지출금액, 지출항목, 취미에 따라 유의한 차이가 있었다. 둘째, 성인대학생과 일반대학생의 일반적 특성에 따른 대인관계의 차이를 알아본 결과 성별, 학년, 한 달 월급(용돈), 한 달 지출금액, 지출항목, 취미에 따라 차이가 있었다. 셋째, 성인대학생과 일반대학생의 물질주의 가치관과 대인관계의 높은 상관관계를 보였다. 넷째, 성인대학생과 일반대학생의 물질주의 가치관은 대인관계의 하위요인에 모두 유의한 영향을 미쳤다. 이상의 연구결과는 성인대학생과 일반대학생 구분 없이 물질주의 가치관이 대인관계에 부정적인 영향을 미친다는 점을 시사한다.

• Biomolecules & Therapeutics
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• 제14권4호
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• pp.194-201
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• 2006

The general pharmacological properties of GCSB-5, a herbal formulation consisting of 6 Oriental herbs(Ledebouriellae Radix, Achyranthis Radix, Acanthopanacis Cortex, Cibotii Rhizoma, Glycine Semen and Eucommiae Cortex), were investigated in mice, rats, guinea pigs and rabbits. The administration of GCSB-5 had no effect on general behavior, and did not influence the central nervous system. Mean blood pressure, heat1 and respiratory rate and contractile response of the isolated guinea pig atrium were unaffected by the treatment of GCSB-5. Addition of GCSB-5 did not cause spontaneous relaxation and contraction of the isolated guinea pig ileum and rat uterus. And also, GCSB-5 had no effect on the gastrointestinal system and the blood system of the animals examined in this study. GCSB-5, at higher doses(1,000 and 3,000 mg/kg), increased the urinary excretion of electrolytes, however, the urine volume and pH in rats were unaffected. Taken together, these results indicate that GCSB-5 does not induce any adverse effects in experimental animals and is expected to have no significant general pharmacological activities.

• BMB Reports
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• 제57권2호
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• pp.116-121
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• 2024

We investigated the therapeutic potential of bone marrow-derived mesenchymal stem cell-conditioned medium (BMSC-CM) on immortalized renal proximal tubule epithelial cells (RPTEC/TERT1) in a fibrotic environment. To replicate the increased stiffness characteristic of kidneys in chronic kidney disease, we utilized polyacrylamide gel platforms. A stiff matrix was shown to increase α-smooth muscle actin (α-SMA) levels, indicating fibrogenic activation in RPTEC/TERT1 cells. Interestingly, treatment with BMSC-CM resulted in significant reductions in the levels of fibrotic markers (α-SMA and vimentin) and increases in the levels of the epithelial marker E-cadherin and aquaporin 7, particularly under stiff conditions. Furthermore, BMSC-CM modified microRNA (miRNA) expression and reduced oxidative stress levels in these cells. Our findings suggest that BMSC-CM can modulate cellular morphology, miRNA expression, and oxidative stress in RPTEC/TERT1 cells, highlighting its therapeutic potential in fibrotic kidney disease.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1990년도 제29차 춘계학술대회
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• pp.199-200
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• 1990

• 대한치과마취과학회지
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• 제12권4호
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• pp.223-227
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• 2012

Autism patients in general have bad oral hygiene. It is hard for autism patients to get dental treatment as poor communication. Therefore, they may have to be treated by deep sedation or general anesthesia in numerous cases. However, this process requires induction with mask, so it is not easy to do for disobliging autism patient. Midazolam is a water-soluble benzodiazepine, has been used in pediatric dentistry or dentistry for the handicapped because of rapid onset. Midazolam can be administered through oral, rectal, intramuscular,intravenous, and intranasal (IN) routes. IN route of midazolam may be considered as effective way to allay for uncooperative autism patients before general anesthesia. In this case report, two autism patients required dental treatment. Intranasal spray of midazolam before general anesthesia was safe and effective procedure of behavioral management.

• Korean Journal of Mathematics
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• 제24권4호
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• pp.647-662
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• 2016

In this paper, we study Lipschitz continuous, the boundedness and compactness of the composition operator $C_{\phi}$ acting between the general hyperbolic Bloch type-classes ${\mathcal{B}}^{\ast}_{p,{\log},{\alpha}}$ and general hyperbolic Besov-type classes $F^{\ast}_{p,{\log}}(p,q,s)$. Moreover, these classes are shown to be complete metric spaces with respect to the corresponding metrics.

• Korean Journal of Mathematics
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• 제28권3호
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• pp.405-419
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• 2020

The zeroth-order general Randić index ⁰R_α(G) of the graph G is defined as ∑_u∈V(G)d(u)^α, where d(u) is the degree of vertex u and α is an arbitrary real number. In this paper, the maximum value of zeroth-order general Randić index on the graphs of order n with a given clique number is presented for any α ≠ 0, 1 and α ∉ (2, 2n-1], where n = |V (G)|. The minimum value of zeroth-order general Randić index on the graphs with a given clique number is also obtained for any α ≠ 0, 1. Furthermore, the corresponding extremal graphs are characterized.

• East Asian mathematical journal
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• 제26권1호
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• pp.59-67
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• 2010

In this paper, we suggest and analyze some three step iterative scheme for finding the common elements of the set of the solutions of the extended general variational inequalities involving three operators and the set of the fixed points of nonexpansive mappings. We also consider the convergence analysis of suggested iterative schemes under some mild conditions. Since the extended general variational inequalities include general variational inequalities and several other classes of variational inequalities as special cases, results obtained in this paper continue to hold for these problems. Results obtained in this paper may be viewed as a refinement and improvement of the previously known results.