• Journal of Microbiology and Biotechnology
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• 제31권11호
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• pp.1559-1567
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• 2021

The root bark of Morus alba L. has cytotoxic activity against several types of cancer cells. However, little is known about its chemopreventive mechanisms and bioactive metabolites. In this study, we showed that M. alba L. root bark extracts (MRBE) suppressed β-catenin response transcription (CRT), which is aberrantly activated in various cancers, by promoting the degradation of β-catenin. In addition, MRBE repressed the expression of the β-catenin/T-cell factor (TCF)-dependent genes, c-myc and cyclin D1, thus inhibiting the proliferation of RPMI-8226 multiple myeloma (MM) cells. MRBE induced apoptosis in MM cells, as evidenced by the increase in the population of annexin VFITC-positive cells and caspase-3/7 activity. We identified ursolic acid in MRBE through LC/mass spectrum (MS) and observed that it also decreased intracellular β-catenin, c-myc, and cyclin D1 levels. Furthermore, it suppressed the proliferation of RPMI-8226 cells by stimulating cell cycle arrest and apoptosis. These findings suggest that MRBE and its active ingredient, ursolic acid, exert antiproliferative activity by promoting the degradation of β-catenin and may have significant chemopreventive potential against MM.

• 유통과학연구
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• 제7권4호
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• pp.27-36
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• 2009

본 연구는 농산물 및 농식품 수출 확대를 위한 애로요인과 문제점, 개선 방안을 조사·연구하여 향후 우리나라 농산물 및 농식품의 세계화를 위한 기초 자료를 제공하는데 연구의 목적을 두고 실행하였다. 농산물 및 농식품 수출 문제점은 전반적으로 모두 높다고 인식하였고, 신규 바이어 발굴 및 해외시장 개척과 마케팅 전문인력 부족이 가장 큰 원인으로 조사되었다. 농산물 수출 지원제도의 문제점은 인지도는 상당히 높지만 절차가 까다롭고 지원에 있어 업체의 선정수가 적어 알고는 있으나 혜택을 받지 못한다는 문제점이 지적되었다. 이를 위해서는 수출 지원제도에 대한 홍보와 교육이 필요하고, 더불어 수출 지원제도의 확대와 제도의 개선이 필요하다는 것을 알 수 있었다. 마지막으로 수출 증대 방안과 관련하여 농산물 수출 증대 저해 요인으로 경영규모 및 생산기반 취약과 수출 마인드 및 전문 인력 미비가 가장 높게 나타난 관계로, 농산물 수출업체들이 대부분 중소기업이라는 점을 감안할 때 해외시장 개척과 마케팅활동의 역량이 부족하다는 것을 예측하고, 이들의 문제점을 해결하기 위한 정부차원의 해외시장 개척과 마케팅 협조 방안이 필요한 실정으로 분석되었다.

• 한국농공학회논문집
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• 제59권2호
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• pp.13-18
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• 2017

Farmers seek for high profitability by increasing the best use of land, and the selection of crops is the first and basic way to achieve their goals. When farmers select crops, the climate, price and productivity of crops are usually considered at the first stage. However, a crucial factor is to understand general characteristics of soils where the crops were grown, but many farmers are lacking in detailed knowledge about soils. The purpose of this study is to search and analyses factors based upon related soil and others in decision-making for the selection of crops. In result, the cultivated rate of the top 5 corps in the suitable areas for cultivation (SAC) is only 53 % which shows most farmers are plants their crops in unsuitable sites. To examine factors influencing on the selection of crops except for soils, surveys about their farm characteristic and Korea Soil Information System (KSIS) were conducted. The result of survey shows 20 % of farmers know KSIS. To increase that rate, there were many changes on soil's characteristic, and at the same time, climate conditions should be updated. It can be expected to increase the rate of farmers' utilization of KSIS.

• 농촌지도와개발
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• 제11권1호
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• pp.53-65
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• 2004

The purposes for this study was to provide information for developing educational programs for U-turn farmers' based on their needs on rural settlement. Special objectives of the study were; 1) to survey the general characteristics of U-turn farmers including motives. preparation, and education, 2) to investigate problems and difficulties of the U-turn farmers in rural settlement 3) to identify the reasons for success and failure in U-turn filming, and 4) to provide information in developing programs for U-turn farmers. Data for the study were collected from 526 U-turn farmers throughout the country, and after data cleaning, 494 questionnaires were used for data analysis. Based on the results of this study, the following were recommended for further development of U-turn farming programs; 1) to facilitate and expand continuous surveys on the motives. preparation, education and information for U-turn farmers will be neceassary to update the important and current information on U-turn farming. 2) Further examination of the problems and difficulties of U-turn farmers would be necessary to develop appropriate policies and educational programs for U-turn farming. 3) continuous investigations on the reasons for success and failure of U-turn farming would be necessary to develop appropriate apicultural policies. 4) for more effective educational programs for U-turn farmers. selection of educators, institution, curricular and timing etc. Should be carefully designed to meet the practical needs of the U-turn farmers. 5) more research activities should be encouraged to improve program development and implementation of U-turn farming.

• 한국지역사회생활과학회지
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• 제16권3호
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• pp.25-36
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• 2005

Recent trends in agricultural globalization have brought on a crisis to our already impoverished Korean farmers. This study was proposed to assist in comparing the health and dietary characteristics of farmer families that have chronic disease patients to farmer families that do not have chronic disease patients. For the study, 1870 families were selected from 9 rural Korean provinces. Trained evaluators interviewed farmer housewives to collect demographic, health behavior, and dietary relative information about family members. Statistical analyses were performed using SAS (ver 8.2). Chi-square tests and General Linear Models were also used. In general, patient family members were older than non-patient family members. For patient families, the mean age was 70.4 for husbands and 64.3 for wives. For non-patient families, the mean age was 64.2 for husbands and 57.3 for wives. Therefore we analyzed the data after we stratified the subjects based on the wife's age of 65. Patient families snacked less and 'dined out' less than non-patient families. However, they consumed cookies more frequently, and milk and fruits less frequently, when compared to non-patient families. There were no significant differences in nutrient supplementation, and/or instant food intake frequencies between patient families and non-patient families. Sixty-two percent of patient family members complained about health problems such arthritis, lumbago, numbness, shoulder pain, dizziness, and others, whereas 52olo of non-patient family members complained about Farmers' syndrome. Husband cigarette smoking was not significantly different among groups. However, the smoking patterns of the wives was significantly higher in patient families. Alcohol consumption was also higher in patient families. In summary, it was determined that rural patient families had poorer dietary behavior and poorer health in general, when compared to non-patient families, and accordingly, diverse community-level health and nutritional support are suggested to solve the farmers' health problems and to improve their quality of life.

• International Journal of Computer Science & Network Security
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• 제24권7호
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• pp.128-142
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• 2024

Creation and implementation of export-oriented strategy is an urgent issue of economic development of any country. In an export-oriented model of economic development, exports should be a means of promoting economic growth and a tool to strengthen existing and potential competitive advantages. Agricultural production is the key factor in exports and the source of foreign exchange earnings in many countries. However, the export potential of agricultural producers may be inefficiently fulfilled due to the heterogeneity of countries in terms of economic development, trade relations and border policy. The aim of the research is to study the nature, main trends and problematic aspects of fulfilling the export potential of agricultural production in the context of aggravating food crisis. The study involved general scientific methods (induction and deduction, description, analysis, synthesis, generalization) and special (statistical method, economic analysis, descriptive statistics and interstate comparisons, graphical method). The need to ensure food security by countries around the world urges the importance of the agricultural sector as a catalyst for economic development, sources of foreign exchange earnings, investment direction, etc. The study of agricultural specialization led to the conclusion that wheat and sugar are goods with the highest export potential. It is substantiated that the countries of South America, OECD, North America and Europe have the highest level of realization of export potential of agricultural production, and African countries are import-dependent. In addition, the low export orientation of Africa and Asia due to the peculiarities of their natural and climatic conditions is established based on the assessment of export-import operations in the regional context. The internal and external export potential of each of the regions is analysed. Economic and mathematical simulation of assessing the impact of the most important factors on the wheat exports volumes was applied, which allowed predicting wheat exports volume and making sound management decisions regarding the realization of the export potential of agricultural companies. The inverse correlation between the exports volume and wheat consumption per capita, and the direct correlation between the effective size and area of land used for wheat cultivation was established through the correlation and regression analysis.

• 한국지형학회지
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• 제24권3호
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• pp.149-159
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• 2017

Coastal dunes have many environmental and ecological socio-economic importances; various human activities, however, have impaired their structures and functions over the years. In 2016, environmental survey on coastal sand dune was carried out to report the present status and update the coastal sand dune list in 2001. This research analyzed the survey data in terms of geomorphological and socio-economic aspects. A list of the 189 coastal sand dune and information was updated by province. A 36.5% reduction in coastal sand dune area have been identified for using agricultural land, development area since the approximately 1940-50s. Development area in coastal sand dune covered small area as 5%, the use intensity was relatively hard. Furthermore, the difference by province also showed. Approximately 80% of the development area was concentrated in 20% of total sand dune several sand dune. It is generally accepted that coastal sand dunes were exposed high development pressure. However the result means that the general brief dose not apply for all sand dune. Therefore, characteristics of each sand dune should be analyzed and concerned the diverse management plans.

• 한국균학회지
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• 제10권1호
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• pp.1-6
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• 1982

한국(韓國)에서 이 균류(菌類)의 4속(屬) 7종(種)이 저자(著者)(1981)들에 의해 이미 보고(報告)되었는데 이 논문(論文)에서는 5종(種)을 추가(追加)한다. 그것들은 Dichomyces vulgatus Thax., Laboulbenia fasciculata Peyr., L. rougetii Mont et Robin. 그리고 L. tachys Thax.이다.

• 한국환경과학회지
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• 제27권11호
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• pp.1105-1115
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• 2018

The aim of this study was to collect crucial data for the improvement of water quality and ecosystem conservation by analyzing water samples, sediments, benthic macroinvertebrates, and fish in the Seosan reservoir. The average values of water quality parameters from 2001 to 2016 were a chemical oxygen demand of 10 mg/L, total nitrogen of 1.22 mg/L, and total phosphorus of 0.074 mg/L. Cadmium was detected in the range of 0.531-0.748 mg/kg in the reservoir sediment. Fish belonging to 6 families and 9 species were identified in the reservoir. The dominant species were Carassius auratus and Micropterus salmoides. Benthic macroinvertebrates belonging to 22 families and 28 species were identified. The ecological score of the benthic macroinvertebrate community was 15 inside the reservoir (St. 2). Micropterus salmoides, an invasive alien species, was determined to be the subdominant fish species based on the number of captures, and the presence of the invasive species, Sicyos angulatus L. and Paspalum distichum L. was confirmed among the land flora.

• Asian-Australasian Journal of Animal Sciences
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• 제32권4호
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• pp.585-591
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• 2019

Objective: This study investigated carcass characteristics and meat quality of purebred Pakchong 5, crossbred pigs sired by Pakchong 5, and crossbred pigs sired by Duroc. Methods: Forty-eight pigs (average body weight of 22.25 kg) were composed of three groups as purebred Pakchong 5 (PP), Large $White{\times}Landrace$ pigs sired by Pakchong 5 (LWLRP), and Large $White{\times}Landrace$ pigs sired by Duroc (LWLRD). Each group consisted of eight gilts and eight barrows. At 109-day-raising period, pigs were slaughtered, and carcass characteristics were evaluated. Longissimus thoracis (LT) muscles from left side of carcasses were evaluated for meat quality and chemical composition. Data were analyzed using general linear model procedure, where group, sex, and their interaction were included in the model. Results: The PP had greater carcass, total lean, and ham percentages than crossbred pigs (p<0.05). LWLRP had thicker backfat and more carcass fat percentage than LWLRD (p<0.05). There were no differences (p>0.05) on cutting percentages from tender loin, loin, boston butt, and picnic shoulder among groups. The PP and LWLRP had larger loin eye area (LEA) than LWLRD (p<0.05). Gilts had more loin percentage and lower $L^*$ value than barrows (p<0.05). No meat color parameters ($L^*$, $a^*$, and $b^*$) were affected by groups (p>0.05). PP and LWLRP had larger muscle fiber diameters than LWLRD (p<0.05). However, water holding capacity, Warner-Bratzler shear force values, and chemical composition of LT were not affected by group or sex (p>0.05). Conclusion: Pakchong 5 purebred has good carcass and lean percentages. Compared to Duroc crossbred pigs, Pakchong 5 crossbreds have similar carcass and lean percentages, larger LEA, and slightly more carcass fat, with comparable meat quality and chemical composition. Pakchong 5 boars are more affordable for very small- to medium-scale pig producers.