• Asian-Australasian Journal of Animal Sciences
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• v.15 no.11
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• pp.1653-1658
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• 2002

The objectives of this study were to examine calpain activity and meat tenderness by three different feeding patterns in Korean native cattle (KNC). Total forty-five animals were assigned each fifteen in long term restriction feeding (LTFR), long-term restriction feeding and hormone treatment (LTFR-tH), and short term non-restriction feeding (STFNR), respectively. Concentrate was restricted based on body weight in exp 1 and 2. However, it was fed ad libitum in exp. 3. Hormonal implantation was made with $M-PO^{TM}$ for bulls and with $F-TO^{TM}$ for heifers at 18, 20, 22 months of age in exp. 2. Animals were purchased (3-5 month old) from local cattle market and managed in two local farms and university research unit at three different years. Animals were slaughtered at 24 months for long-term trial and at 18 month for short term-trial. Loin and tender loin muscle was used for calpain activity and meat quality. Calpain proteolytic system was not changed by treatment. However, calpastatin activity was low in short-term trial. The calpain and calpastatin activity is reciprocal relationship, therefore, the high calpain activity may effect on quality grade. The shear force value was decreased as the processing of aging after postmortem. On the other hand, the cooking loss was significantly higher in short-term than in long-term trial, and then gradually decreased by the aging. Hormone implants to increase meat yield influenced to calpastatin activity more powerfully than calpain activity to meat tenderness. In meat color-a*, there was not significant difference in loin. Meat color-b* was decreased as postmortem aging time increased in tenderloin. Western blots were done to learn whether these proteins are degraded during postmortem storage and whether this degradation temporally parallels the decrease of shear force value. Vinculin was detected at 0 day and 1 day and degraded after 3 day. In conclusion, Calpain activity was affected slightly on meat tenderness. But meat tenderness was influenced by calpastatin, more effectively.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.17
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• pp.7169-7174
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• 2014

Background: NPAS2 is a product of the circadian clock gene. It acts as a putative tumor suppressor by playing an important role in DNA damage responses, cell cycle control and apoptosis. Chronic lymphocytic leukemia (CLL) appears to be an apoptosis related disorder and alteration in the NPAS2 gene might therefore be directly involved in the etiology of CLL. Here, the Ala394Thr polymorphism (rs2305160:G>A) in the NPAS2 gene was genotyped and melatonin concentrations were measured in a total of seventy-four individuals, including thirty-seven CLL cases and an equal number of age- and sex-matched healthy controls in order to examine the effect of NPAS2 polymorphism and melatonin concentrations on CLL risk in a Pakistani population. Materials and Methods: Genotyping of rs2305160:G>A polymorphism at NPAS2 locus was carried out by amplification refractory mutation system-polymerase chain reaction (ARMS-PCR). Melatonin concentrations were determined by enzyme linked immunosorbent assay (ELISA). Statistical analysis was performed using Statistical Package for Social Sciences software. Results: Our results demonstrated no association of the variant Thr genotypes (Ala/Thr and Thr/Thr) with risk of CLL. Similarly, no association of rs2305160 with CLL was observed in either females or males after stratification of study population on a gender basis. Moreover, when the subjects with CLL were further stratified into shift-workers and non-shift-workers, no association of rs2305160 with CLL was seen in either case. However, significantly low serum melatonin levels were observed in CLL patients as compared to healthy subjects (p<0.05). Also, lower melatonin levels were seen in shift-workers as compared to non-shift-workers (p<0.05). There was no significant difference (p>0.05) in the melatonin levels across NPAS2 genotypes in all subjects, subjects with CLL who were either shift workers or non-shift-workers. General Linear Model (GLM) univariate analysis revealed no significant association (p>0.05) of the rs2305160 polymorphism of the NPAS2 gene with melatonin levels in any of the groups. Conclusions: While low melatonin levels and shift-work can be considered as one of the risk factors for CLL, the NPAS2 rs2305160 polymorphism does not appear to have any association with risk of CLL in our Pakistani population.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4223-4228
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• 2013

Background: The purpose of this study was to determine the clinical and dosimetric factors associated with acute esophagitis (AE) in lung cancer patients treated with conformal radiotherapy (RT) in Turkey. Materials and Methods: In this retrospective review 104 lung cancer patients were examined. Esophagitis grades were verified weekly during treatment, and at 1 week, and 1 and 2 months afterwards. The clinical parameters included patient age, gender, tumor pathology, number of chemotherapy treatments before RT, concurrent chemotherapy, radiation dose, tumor response to RT, tumor localization, interruption of RT, weight loss, tumor and nodal stage and tumor volume. The following dosimetric parameters were analyzed for correlation of AE: The maximum ($D_{max}$) and mean ($D_{mean}$) doses delivered to the esophagus, the percentage of esophagus volume receiving ${\geq}10$ Gy ($V_{10}$), ${\geq}20$ Gy ($V_{20}$), ${\geq}30$ Gy ($V_{30}$), ${\geq}35$ Gy ($V_{35}$), ${\geq}40$ Gy ($V_{40}$), ${\geq}45$ Gy ($V_{45}$), ${\geq}50$ Gy ($V_{50}$) and ${\geq}60$ Gy ($V_{60}$). Results: Fifty-five patients (52.9%) developed AE. Maximum grades of AE were recorded: Grade 1 in 51 patients (49%), and Grade 2 in 4 patients (3.8%). Clinical factors had no statistically significant influence on the incidence of AE. In terms of dosimetric findings, correlation analyses demonstrated a significant association between AE and $D_{max}$ (>5117 cGy), $D_{mean}$ (>1487 cGy) and $V_{10-60}$ (percentage of volume receiving >10 to 60 Gy). The most significant relationship between RT and esophagitis were in $D_{max}$ (>5117 cGy) (p=0.002) and percentage of esophageal volume receiving >30 Gy ($V_{30}$ >31%) (p=0.008) in the logistic regression analysis. Conclusions: The maximum dose esophagus greater than 5117 cGy and approximately one third (31%) of the esophageal volume receiving >30 Gy was the most statistically significant predictive factor associated with esophagitis due to RT.

• Journal of agricultural medicine and community health
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• v.25 no.2
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• pp.293-302
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• 2000

The relationship between sodium intake and stomach cancer risk has been studied much in Japan but a great portions still remain controversial. There has been few studies on relationship between sodium intake and stomach cancer in Korea. The goal of this nested case-control study is to investigate the association between sodium intake and stomach cancer risk in a rural county of Korea We estimated sodium intake indirectly by the threshold of salt-water taste of patients. This study was based on both of the data from 'Kangwha Cohort Study' which had been conducted from March 1985 and 'Kangwha Community Cancer Registry' which had been launched on July in 1982 by the College of Medicine, Department of Preventive Medicine. Yonsei University. A total of 145 patients who developed stomach cancer in Kangwha County were initially recruited as the case group. We tried to get two community-controls per stomach cancer case by matching age and gender. Finally we got information from 90 cases and 146 controls about the threshold of the salt taste and preference of salty food and so on. Some 79% of the information about ease group came from proxy respondents and 56% among controls. Risk ratios of developing stomach cancer adjusted for smoking, body mass index and self-stated health level were estimated. No statistically significant association between the threshold of salt taste and stomach cancer risk found in this study. We recommend some further studies utilizing urinary salt excretion, diet record method for better estimating of salt intake with a paticular emphasis on interaction effect between salty and spicy food in hospital-based case-control study designs.

• Korean Journal of Hospice Care
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• v.2 no.1
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• pp.41-57
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• 2002

This study was done to examine spiritual well-being of hospice care service volunteers for the purpose of providing them with programs promoting coping skills in response to the wholistic needs of patient effectively, also providing data for professional or nonprofessional hospice training program. Subjects were 123 volunteers serving in 6 hospice centers in Jeonbuk province at present. Data collection were done from 16 Oct. 2000 to 17 Nov. 2000. questionnairs were consisted of activities of hospice care service volunteer and spiritual well-being. The study results were as follows 1.Mean of activities of hospice care service volunteers were 2.433, those activities were divided into 5 categories such as spiritual, activities of volunteer for themselves, psychosocial, physical area and bereavement. The highest mean score was spiritual area 2.578, activities of volunteers for themselves 2.525, psychosocial area 2.456, physical area was 2.359 and the lowest mean score was bereavement area 2.130. 2.Spiritual well-being of hospice care service volunteers was 5.25, the highest mean. In subcategories of spiritual well-being, religious spiritual well-being was higher than existential spiritual well-being, mean score for each one was 5.41, 5.10. 3.Statistically significant relations among demographic characteristics such as gender(t=2.72, P=.008), status of marriage(t=6.067, P=.003), occupation(F=3.795, P=.025), frequency of visiting for volunteered hospice care(F=3.833, P=.024) were noted. 4.Statistically significant demographic characteristics of hospice service volunteers was religion(t=-4.38, p=0.000), status of marriage(F=3.505, p=0.033), frequency of visiting for volunteered hospice care(F=3.107, p=0.048), level of satisfaction from hospice care volunteer service(F=3.610, p=0.030), hospice service volunteers doing more home visiting(5-9times/month) had higher status of spiritual well being than volunteer with less home visiting(1-4times/month) 5.A significant relationship between activities of hospice service volunteers and status of spiritual well-being was noted(r=.236, p=.004), activities of hospice service volunteers was related to both subcategories of spiritual well-being such as religious well-being(r=.210, p=.010) and existential well-being(r=.208, p=.011). From the results of the study It is noted that status of spiritual well-being for hospice volunteers influences on service activities. It means spiritual well-being should be considered as a essential character for hospice service volunteers, it also means that managing and maintaining of status of spiritual well-being for hospice service volunteers is important. On the base of the study recommendation are made as follows: 1.Considering status of spiritual well-being for hospice care service volunteers is needed to promote hospice care activities. 2.It is necessary to develope spiritual well-being programs for hospice care service volunteers and further study for effect validation of them is needed. 3.Further study to sort out effecting variables for hospice care service volunteer activities is needed. 4.It will be desirable to have spiritual well-being information included in the hospice education program.

• Korean Journal of Poultry Science
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• v.42 no.2
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• pp.133-137
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• 2015

We investigated the effects of supplementing low energy diets with lysolecithin and sodium stearoyl-2-lactylate on growth performance and nutrient digestibility in broilers. A total of 768 1-d-old Ross 308, mixed gender broiler chicks with an average initial body weight of 44.3 g, were used in a 35-d feeding trial. Broiler chicks were sorted into pens with 16 birds per pen and every treatment consisted of 12 pens (192 chickens per treatment). Treatments were: 1) PC: basal diet, 2) NC: PC-100 kcal, 3) T1: NC+ 0.08% lysolecithin, and, 4) T2: NC + 0.04% sodium stearoyl-2-lactylate. Body weight gain (BWG), feed intake (FI) and feed conversion ratio (FCR) were measured on a weekly basis. Chromium oxide was added to the diets at 0.2% on the last week of the experiment, as a marker for digestibility. Dietary treatments had no effect on growth performance for days 1 to 21. Low energy diet supplemented with lysolecithin and sodium stearoyl-2-lactylate in phase 2 (d 21 to 35) improved body weight gain (P<0.05). Addition of lysolecithin and sodium stearoyl-2-lactylate to the diets improved the digestibility of energy and nitrogen (P<0.05), but digestibility of dry matter was not affected. Overall, addition of an emulsifier to the diet of broiler chickens in the late growth phase enhanced growth performance and digestibility of energy and nitrogen.

• Korean Journal of Social Welfare
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• v.39
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• pp.180-209
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• 1999

As a pioneering study on wife rape, this study focuses on identifying the prevalence, the correlates of the individual social class and domestic violence background, and the perception of wife rape. This study uses the data based on the survey 224 married men and women who reside in Daegu, Korea. The result of this study shows that about 42.4% married men have experienced any type of wife rape. The most prevalent wife rape is force only wife rape(36.4%). Battering rape(12.1%) and sadistic rape(10.4%) are also found as significant coercive sexual issue among Korean couples. Monthly income and child abuse experience are found as significant predictors for the wife rape of married men. In addition, wife's religious enthusiasm is also negatively correlated with wife rape propensity, although the effect is not strong. The living standards is found as a strong correlate of women's propensity of being raped from their husbands. Thus, our practical attention should be given to those who have financial difficulties in low economic status, and to those who have significant child abuse experience, in order to prevent wife rape. Overall, married men and married women show pretty negative perceptions of wife rape, however, some of them are still positive of it. It is interesting that married men show a very defensive attitude against the proposal of establishing legal punishment for the people who commit wife rape. According to the gender, there is a considerable difference between men and women in terms of both the degree of acceptance of, and the demand for legal punishment of wife rape. It is problematic that the married women with a greater experience of being raped by husbands show far greater tolerance of wife rape than those with a less experience of it. These findings give us significant practical implications for social work intervention.

• Korean Journal of Social Welfare
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• v.57 no.3
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• pp.133-164
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• 2005

This study examined the effects of children's perceived stress of economic strain, resulting family conflict, and stress coping strategies on their adjustment. Dimensions of children's adjustment studied in this research were problem behaviors (aggression, delinquency, withdrawal and anxiety depression) and school adjustment. Interaction effects between children's stress variables and coping strategies on the adjustment were also explored. 1,115 fifth to eighth graders from Chungbuk regions participated in self-administered structured questionnaires. Data were processed with SPSS PC 10.0 statistical package. Results were: First, the level of children's problem behaviors and school adjustment indicated differences according to their academic achievement, gender, and their age. Middle schoolers with rather low grade average reported higher level of aggression, delinquency, withdrawal and that of depression/anxiety. Boys tended to be more prone to external problems while girls to internal problems. Second, stresses originated from children's perceived economic strain and family conflicts showed consistent meaningful explanatory power on adjustment. Boys' adjustment was influenced by stress from economic strain and family conflict while girls by family conflict and academic achievements. The support seeking coping strategy among others was the most popularly employed coping strategy of children followed by aggressive coping strategy. In boys' cases, interaction effects of stress and coping strategies were significant in all of the adjustment variables, the more frequent the use of support seeking coping strategies, the lower the problem behavior, while interaction effect of family conflict stress and support seeking coping strategies played the opposite significant role in girls' cases. Further research efforts are required. Research results suggest; when developing a program facilitating children's adjustment, training on stress coping strategies should be considered as a potent new arena of interest.

• Korean Journal of Social Welfare
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• v.65 no.3
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• pp.29-52
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• 2013

This study examined how middle-aged and elderly persons allocated their time in overall perspective and whether the patterns were varied by age, socio-demographic factors, and the interaction effect between them. This study analyzed the 2009 Time Use Survey Data (17,096 time-diaries of people aged 45 or more) of the National Statistical Office using tobit regression model. The main results are as follows. First, middle-aged and elderly people gradually decreased paid work times. Second, the patterns of time allocation were varied by age, gender, education level, marital status and household type(Agricultural/non-agricultural). Third, there were interaction effects between age and the socio-demographic factors on paid work time and leisure time. Highly educated or urban persons were likely to have less time in paid work less than other groups with increasing age. And females were likely to have less time in domestic labor and care work than males with increasing age. But they had more time in social and economic productive activities than males. Based on these findings, this study suggests comprehensive approach to analyze the time use of elderly beyond economic working time or leisure time. To establish effective ageing society policy, it is necessary to consider the time allocation of elderly which divided into the social stratification.

• Journal of the Korean Data and Information Science Society
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• v.28 no.6
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• pp.1457-1469
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• 2017

Private education expenses is one of the key issues in Korea and there have been many discussions about it. Academically, most of previous researches for private education expenses have used multiple regression linear model based on ordinary least squares (OLS) method. However, if the data do not satisfy the basic assumptions of the OLS method such as the normality and homoscedasticity, there is a problem with the reliability of estimations of parameters. In this case, quantile regression model is preferred to OLS model since it does not depend on the assumptions of nonnormality and heteroscedasticity for the data. In the present study, the data from a survey on private education expenses, conducted by Statistics Korea in 2015 has been analyzed for investigation of the impacting factors for private education expenses. Since the data do not satisfy the OLS assumptions, quantile regression model has been employed in Bayesian approach by using gibbs sampling method. The analysis results show that the gender of the student, parent's age, and the time and cost of participating after school are not significant. Household income is positively significant in proportion to the same size for all levels (quantiles) of private education expenses. Spending on private education in Seoul is higher than other regions and the regional difference grows as private education expenditure increases. Total time for private education and student's achievement have positive effect on the lower quantiles than the higher quantiles. Education level of father is positively significant for midium-high quantiles only, but education level of mother is for all but low quantiles. Participating after school is positively significant for the lower quantiles but EBS textbook cost is positively significant for the higher quantiles.