• Applied Microscopy
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• 제18권1호
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• pp.92-102
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• 1988

살리실산이 백서 와우의 나선신경절의 미세구조에 미치는 영향을 전자현미경으로 관찰하였다. 생후 $4{\sim}5$주의 Sprague-Dawley계 백서에 $500{\sim}600mg/kg$의 용량으로 살리실산 나트륨을 7일간 피하주사한 후에 각각 24시간(1군), 6주(2군), 10주(3군) 경과 후에 와우조직을 얻어 나선신경절에 나타나는 미세구조의 변화를 관찰하였다. 1. 1군에서는 신경절세포와 위성세포 그리고 Schwann cell의 세포질내에 다양한 크기의 막소구의 팽창이 나타났으며 Schwann cell 내에서는 미토콘드리아가 팽윤되거나 다낭성 세포소체를 형성하였다. 2. 2군에서는 신경절세포나 위성세포내의 막소구들이 더욱 팽창하고 그 일부는 융합하여 세포질이 감소하였다. Type I 세포의 신경 세포체나 신경섬유 주위를 싸고 있는 수초는 각층 사이의 거리가 멀어지거나 일부는 소실되었고, Type II 세포내에는 신경미섬유가 증가하였다. 3. 3군에서는 수초의 변형 및 파괴로 신경절세포의 세포질 이탈이 관찰되었고 Corti기 및 골성 나선판에 위치하는 신경섬유들의 소실이 관찰되었다. 이상의 결과를 종합하면 나선신경절세포와 그 주위를 둘러싸는 위성세포 및 Schwann cell은 과량의 살리실산 나트륨 투여후에 미세구조의 변화를 보였으며 1군에서 2군, 3군으로 갈수록 변화가 더욱 현저하였다.

• 대한골관절종양학회지
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• 제12권1호
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• pp.63-70
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• 2006

목적: 이 연구의 목적은 말단 신경을 침범하는 결절종을 가진 환자의 수술적 치료를 고찰하는 데 있다. 대상 및 방법: 1995년부터 2000년까지 결절종으로 인한 신경적 증상을 가지고 있었고 수술적으로 치료받았던 12예의 환자를 대상으로 하였다. 평균 나이는 44.3(15-71)세였다. 압박 받았던 신경은 경골 신경이 3예로 가장 많았고 견갑상 신경, 총 비골 신경, 요골 신경, 척골 신경이 각각 2예, 정중 신경이 1예였다. 동통은 6명의 환자에서 있었고, 감각 이상이나 운동력 저하가 각각 7예의 환자에서 보였고 4명의 환자에서는 이 두 증상이 동시에 있었다. 결과: 술전 동통을 호소하였던 6명 모두 술후 동통은 소실되었다. 술전 감각 이상이 있었던 7명의 환자 중 5명에서 호전이 있었으며 술전 운동력 약화를 보였던 환자 모두 호전이 있었다. 술전 감각 이상과 운동력 약화를 동시에 보였던 환자 4명 중 2명만이 완전한 감각의 회복을 보였고 이는 불량한 예후 인자를 암시한다. 결론: 이러한 압박 신경병증을 일으키는 결절종의 정확한 조기 진단 및 절제는 우수한 임상적 결과를 보인다.

• Archives of Reconstructive Microsurgery
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• 제20권2호
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• pp.121-125
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• 2011

Simple ganglions are most common benign tumor of the hand and wrist. However, cystic adventitial disease is an uncommon vascular anomaly first described in 1947 in the external iliac artery. It usually involves the popliteal artery, although other arteries and veins may also be involved. Radial artery adventitial cysts are found directly within the adventitia, whereas the more common wrist ganglions may extrinsically compress or adhere to the artery walls. The diagnosis is rarely made before surgery because of their similar appearance and location. The authors report a rare case of a 46-year old woman with mucoid adventitial cyst of the radial artery in the wrist.

• Clinical Pain
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• 제18권1호
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• pp.40-43
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• 2019

Carpal tunnel syndrome can be produced by abnormal mass effect due to trauma, ganglion cysts, various soft tissue tumors, musculotendinous variants, and aberrant vascular structures. Persistent median artery is one of the causes of the carpal tunnel syndrome. Thrombosed persistent median artery usually accompanies the anomaly of the median nerve and causes a sudden onset of severe pain and paresthesia. In contrast to previous literature, we report the rare case of gradual onset and mild symptom of a 53-year-old man with a thrombosed persistent median artery but without anomaly of the median nerve and abnormal finding of electrophysiologic study.

• 한방재활의학과학회지
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• 제30권3호
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• pp.163-169
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• 2020

This study reports on the effectiveness of Korean traditional medicine treatment on a patient with right hip pain caused by obturator nerve entrapment due to ganglion cyst. The patient had been misdiagnosed for a stenosis at the other hospital, but he got a different diagnosis this time with the examination. The patient was treated with Korean traditonal medicine, which includes pharmacopuncture, acupuncture, manual treatment (Chuna), and herbal medicine. Numerical rating scale (NRS), Oswestry Disability Index (ODI) and Euroqol five dimension (EQ-5D) index were used as a objective tool for evaluating the patient's symptoms. After treatment, NRS and ODI were decreased, while EQ-5D index was increased. This study suggests that a combined Korean traditional medicine may be effective in reducing symptoms related to obturator nerve entrapment.

• The Korean Journal of Pain
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• 제37권1호
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• pp.3-12
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• 2024

One of the most common sources of spinal pain syndromes is the facet joints. Cervical, thoracic, and lumbar facet joint pain syndromes comprise 55%, 42%, and 31% of chronic spinal pain syndromes, respectively. Common facet joint disorders are degenerative disorders, such as osteoarthritis, hypertrophied superior articular process, and facet joint cysts; septic arthritis; systemic and metabolic disorders, such as ankylosing spondylitis or gout; and traumatic dislocations. The facet pain syndrome from osteoarthritis is suspected from a patient's history (referred pain pattern) and physical examination (tenderness). Other facet joint disorders may cause radicular pain if mass effect from a facet joint cyst, hypertrophied superior articular process, or tumors compress the dorsal root ganglion. However, a high degree of morphological change does not always provoke pain. The superiority of innervating nerve block or direct joint injection for diagnosis and treatment is still a controversy. Treatment includes facet joint injection in facet joint osteoarthritis or whiplash injury provoking referred pain or decompression in mass effect in cases of hypertrophied superior articular process or facet joint cyst eliciting radicular pain. In addition, septic arthritis is treated using a proper antibiotic, based on infected tissue or blood culture. This review describes the diagnosis and treatment of common facet joint disorders.

• 대한족부족관절학회지
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• 제11권2호
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• pp.192-197
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• 2007

Purpose: The purpose of this study is to present our clinical results after surgical treatment in tarsal tunnel syndrome due to space occupying lesions. Material and Methods: We performed surgical decompression for tarsal tunnel syndrome in 20 patients from July 2004 to February 2007. Out of them, thirteen cases were due to space occupying lesions around the tarsal tunnel. The average age at operation was 51.3 years old and the duration from symptom onset to surgery was 16.5 months. The operation included removal of space occupying lesions and tarsal tunnel decompression. The clinical parameters were pain visual analogue scale (VAS), AOFAS scale, and subjective satisfaction. Results: The ganglion cysts were the most frequent causes (ten cases) and synovial chondromatosis in 1 case, neurofibroma in 1 case, talocalcaneal coalition in 1 case. The average follow-up duration was 14.5 months. The AOFAS scale showed significant improvement from 77.8 to 92.7. The average VAS decreased from 6.4 to 2.2. Seven out of thirteen patients were satisfied with the results. The excellent results were shown in six patients, the good results in one patient, the fair result in three patients and the unsatisfactory results in three patients. Conclusion: Favorable results could be obtained in patients with known etiology. But not all cases with surgical decompression of space occupying lesions showed satisfactory results. We assume that the clinical results were related to the multiple factors, not only well performed surgery but also age, size lesions and duration of symptoms, ect.

• 대한수의학회지
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• 제45권4호
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• pp.593-599
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• 2005

An abattoir study on the abdominal fat necrosis in adult cattle was performed pathologically. Grossly, masses of fat necrosis were leekgreen in colour, lobulated on the cut surface, and saponificated in the texture. These necrotic adipose tissues infiltrated usually into neighboring parenchymal organs including intestines and pancreas, leading to fibrosis or atrophy of them. Histopathologically, necrotic fat cells contained acidophilic, opaque, amorphous substance or basophilic fibrillar or granular minerals in their cytoplasms. The lesions of fat necrosis were divided by fibroconnective tissue. With increase of the severity, necrotic fat cells fused each other and then formed fat cysts. In this severe lesion, necrotic fat cells were partialy or completely replaced by macrophages. Multinucleated giant cells were scattered in this lesion. Interestingly, small artery in the lesion of fat necrosis revealed severe thickening of internal elastic membrane. Severe fibrosis was observed in or between the outer longitudinal and inner circular muscular externas causing segregation, degeneration and necrosis of muscle fibers. The nerve cells of Auerbach's and Meissner's plexuses surrounded by fibrosis were degenerated or necrotic. In addition, necrotic fat cells infiltrated into the pancreas, resulting in pancreas atrophy. From these results, it is speculated that fat necrosis might compromise intestinal movement due to necrosis of muscular externa and ganglion cells of Auerbach's and Meissner's plexuses.

• 대한골관절종양학회지
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• 제10권2호
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• pp.79-87
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• 2004

목적: 최근 자기공명영상의 개발로 다양한 연조직종양의 영상의학적 진단이 가능해 졌다. 그러나 연조직종양의 다양한 조직구성이나 시간에 따라 구성분의 변화는 자기공명영상 만으로 악성과 양성 종양조차 감별을 어렵게 한다. 이에 본 저자들은 임상과 자기공명영상의 복합적인 소견으로 악성과 양성 연조직종양을 감별해 보고자 하였다. 대상 및 방법: 병리조직학적으로 확진된 82례(중간성종양을 악성종양으로 포함하여 37례와 염증성 종괴를 양성종양으로 포함하여 45례)를 후향적으로, 임상적 소견으로 연령, 크기, 위치, 그리고 자기공명영상 소견으로 종양경계, T2신호강도양상, 조영제T1신호강도양상, 그리고 조영증강 범위를 연관시켜 분석하였다. 자기공명영상으로 진단이 어렵지 않는 많은 전형적인 지방종과 결절종 그리고 농양같은 낭종은 양성종양 분류에서 제외하였다. 결과: 악성연조직종양은 양성에 비하여 연령으로 21~40세와 61~80세, 크기로 3.0 cm 이상, 발생위치로 몸체-골반-하지, 그리고 자기공명영상에서 불규칙한 경계, 50%이상의 조영증강범위 소견들의 빈도가 높았다. 결론: 발생위치로 몸체-골반-하지 와 상지-어깨-척추 로 나눈 임상소견이 악성과 양성 연조직종양을 감별하는데 통계학적으로 유의성있는 차이를 보였으며 나머지 다른 소견들은 특이적이지는 않았지만 부가적으로 악성과 양성을 감별하는데 도움이 되는 소견이었다.