• Title/Summary/Keyword: Gabon

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Allelic Diversity of MSP1 Gene in Plasmodium falciparum from Rural and Urban Areas of Gabon

  • Mawili-Mboumba, Denise Patricia;Mbondoukwe, Noe;Adande, Elvire;Bouyou-Akotet, Marielle Karine
    • Parasites, Hosts and Diseases
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    • v.53 no.4
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    • pp.413-419
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    • 2015
  • The present study determined and compared the genetic diversity of Plasmodium falciparum strains infecting children living in 2 areas from Gabon with different malaria endemicity. Blood samples were collected from febrile children from 2008 to 2009 in 2 health centres from rural (Oyem) and urban (Owendo) areas. Genetic diversity was determined in P. falciparum isolates by analyzing the merozoite surface protein-1 (msp1) gene polymorphism using nested-PCR. Overall, 168 children with mild falciparum malaria were included. K1, Ro33, and Mad20 alleles were found in 110 (65.5%), 94 (55.9%), and 35 (20.8%) isolates, respectively, without difference according to the site (P>0.05). Allelic families' frequencies were comparable between children less than 5 years old from the 2 sites; while among the older children the proportions of Ro33 and Mad20 alleles were 1.7 to 2.0 fold higher at Oyem. Thirty-three different alleles were detected, 16 (48.5%) were common to both sites, and 10 out of the 17 specific alleles were found at Oyem. Furthermore, multiple infection carriers were frequent at Oyem (57.7% vs 42.2% at Owendo; P=0.04) where the complexity of infection was of 1.88 (${\pm}0.95$) higher compared to that found at Owendo ($1.55{\pm}0.75$). Extended genetic diversity of P. falciparum strains infecting Gabonese symptomatic children and high multiplicity of infections were observed in rural area. Alleles common to the 2 sites were frequent; the site-specific alleles predominated in the rural area. Such distribution of the alleles should be taken into accounts when designing MSP1 or MSP2 malaria vaccine.

Phytochemical and Anti-Termite Efficiency Study of Guibourtia tessmanii (harms) J. Léonard (Kévazingo) Bark Extracts from Gabon

  • NKOGO, Ley-Fleury ELLA;BOPENGA, Christ Stone Arnaud BOPENGA;NGOHANG, Franck Estime;MENGOME, Line Edwige;ANGONE, Sophie ABOUGHE;ENGONGA, Prosper EDOU
    • Journal of the Korean Wood Science and Technology
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    • v.50 no.2
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    • pp.113-125
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    • 2022
  • This study aimed to explore the biodiversity of chemical compounds found in the bark of Guibourtia tessmannii from Gabon, commonly called Kévazingo, and evaluate their anti-termite activity to determine their potential values as a source of development of anti-termite products that can be valued in the fields of fine chemicals and wood preservation. Extraction of G. tessmannii bark powders was carried out using the cold maceration method with trichloroethylene, acetone, ethanol, and water. Phytochemical screening made it possible to highlight groups of chemical families present in the extracts. Anti-termite activity was tested on the wild termites "Cubitermes sp" of the genus Isoptera. The yield of the extracts were 17.11% for the buttress and 13.42% for the height at 6 m. Phytochemical tests revealed that alkaloids, polyphenols, sterols, tannins, reducing compounds, flavonoids, saponins, and anthraquinones were present in the extracts. Results of anti-termite activity indicated that anti-termite activity varied with the different parts of the bark studied, extraction solvent, and concentration (50/50) and (25/75) of the extracts used. The extracts at 50/50 concentration showed a slightly better anti-termite activity compared to the 25/75 concentration. In addition, the buttress Kévazingo or buttress showed the strongest anti-termite activity for the aqueous extract with a survival rate of 0% after 2 days.

Evaluation of the Antimicrobial Activity of Seven Gabonese Medicinal Plants against Methicillin-Resistant Staphylococcus aureus and Salmonella

  • Obiang-Obounou, Brice W.;Kang, Ok-Hwa;Choi, Jang-Gi;Keum, Joon-Ho;Kim, Sung-Bae;Kim, Yong-Sik;Mun, Su-Hyun;Choi, Mi-Sun;Maroufath, Lamidi;Kwon, Dong-Yeul
    • Natural Product Sciences
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    • v.17 no.1
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    • pp.33-37
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    • 2011
  • The plant species reported here are used by traditional healers in Gabon for different ailments such as wounds, malaria, fever, gonorrhea or diarrhea. The aim of this study was to evaluate the antimicrobial activities of 7 plants (Strombosiopsis tetrandra, Tetraberlinia bifoliolata, Dichapetalum barbatum, Guibourtia demeusii, Dacryodes normandii, Manniophytum fulvum, Paropsia grewoides) against different strains of both Methicillin-Resistant Staphylococcus aureus (MRSA) and Salmonella. Disc diffusion was first used to determine the antimicrobial effectiveness of the plants' ethanolic extracts. Then the minimum inhibitory concentrations of the crude extracts of either leaves or stem barks of the 7 plants were determined using broth micro-dilution. The ethanolic plant extracts showed very good activity against both MRSA and Salmonella strains where the MICs ranged from $250\;{\mu}g/ml$ to $1000\;{\mu}g/ml$. The study shows that many of the tested plants used by Gabonese traditional healers have antimicrobial activities and give support to their traditional use.

Influence of Perceived Quality, Price, Risk, and Brand Image on Perceived Value for Smartphone's Consumers in a Developing Country

  • Samadou, Sourou Essono;Kim, Gyu-Bae
    • East Asian Journal of Business Economics (EAJBE)
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    • v.6 no.3
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    • pp.37-47
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    • 2018
  • Purpose - This paper investigates the major determinants of consumer decision making for smartphone's consumers in a developing country in Africa especially in Gabon. Analysis of Perceived Quality, Perceived Price, Perceived Risk, Brand Image, Perceived Value, and Purchase Intention Research design and methodology - In order to proceed the empirical research, online survey was done via email and social media network and data was collected from 289 random respondents. Therefore, to assess the reliability, the validity and test hypothesis Statistical Package for Social Sciences (SPSS) version 21 was used. Results - After data collection and analysis, results have proved that brand image, perceived price does influence perceived quality, and perceived quality negatively influence perceived risk. The results also show perceived risk along with brand image, perceived price and quality could not influence perceived value. The findings also indicate that perceived value slightly influence purchase intentions. Conclusions - The results of the study show that it is essential to develop an understanding of value in the purchasing process. This study should also provide a glimpse to both marketers and manufacturers about consumers' perceptions towards smartphones.

A Report on the Salmonella Cultures Collected in Korea (1972) (1972년도(年度) 한국(韓國)에서 분리(分離)된 쌀모넬라 균속(菌屬)에 관(關)한 보고(報告))

  • Kim, Young-Ja;Kim, Ki-Hong;Ryu, Young-Hat
    • The Journal of the Korean Society for Microbiology
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    • v.8 no.1
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    • pp.1-5
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    • 1973
  • The authors identified 833 Salmonella cultures collected from various parts of the country in 1972. The procedures for the morphological and biochemical tests and for the serological determinations were performed by means of the conventional screening methods recommended by the National Center for Disease Control in U.S.A. The results of the laboratory tests were summerized as follows: 1. Of 833 Salmonella cultures, 1 S. paratyphi A, 1 S. nitra, 1 S. kiel, 1 S. abortusequi, 6 S. paratyphi B, 5 S. abony, 4 S. caledon, 13 S. typhimurium, 2 S. coeln, 1 S. oranienburg, 1 S. thompson, 1 S. bonn, 1 S. gabon, 1 S. colorado, 1 S. richmond, 2 S. berta, 20 S. enteritidis, 1 S. regent, 1 S. london were identified besides 769 cultures of S. typhi. 2. The antibiotics sensitivity tests by means of Ericsson's disc method using seven kinds of antibiotics were carried out, i.e. chloramphenicol, ampicillin, which were widely in common use in the country and the results were compared with that of Salmonella cultures isolated in 1971 as shown in table 4.

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