• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.2
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• pp.158-163
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• 2015

General anesthesia (GA) for dental care in handicapped patients is necessary to facilitate the provision of safe, efficient, and effective quality treatment. The aims of this study were to determine the anesthetic characteristics of handicapped patients in need of dental treatment in these day care units, and to establish for plan to provide better services. 325 patients who had outpatient general anesthesia from January 2005 to March 2014 were assessed for this study. Patients' distribution and treatment patterns were examined. The proportion of male patients (202, 62.2%) was higher than female patients (123, 37.8%) and the largest group of patients were 5 to 10 years old (85, 26.2%). The reasons for general anesthesia included mental and physical disabilities (207, 63.7%), behavior management (84, 25.8%), parent needs (14, 4.3%), and so on. Restorative treatment was the most common procedure with the average of 4.2 teeth treated per one patient and 43 (13.2%) patients underwent general anesthesia for dental treatment more than once. To expand and improve access to the dental care of the disabled, improvement of the health care system, enhancement of their training for dental care by professionals, and enlarging caregivers'understanding of the importance of oral care in the early stages are required.

• Journal of Life Science
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• v.25 no.12
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• pp.1354-1361
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• 2015

This study was aimed to investigate the distribution status and phylogenetic relationship of Myotis aurascens in Jeju Ialnd, which has not clearly confirmed until now. We found three groups of M. aurascens from three different cave enforcements (CEs). The bat population of Jeju Island had smaller levels of HBL and Hfcu, but greater levels of TL, EL, FAL, and Tra than those of the Korean Peninsula population. Jeju bats had wide range in the lengths of FAL and Hfcu comparing to those of European bats. From the bimonthly monitoring to each finding site, we have actually failed to observe those again, estimating that they use those CEs as the daily-roosting place in activating seasons. The sequences of CYTB and COI genes showed identical sequences among Jeju bats tested, indicating that they are maternally related. The results from molecular phylogeny showed that the sequences of these bats located on the same branch with those for M. aurascens in the phylogenetic trees. Besides, the nucleotide sequences of the Jeju bats showed the closest relation with that of Korean Peninsula. Consequently, these findings indicate that the bats of M. aurascens, verified the natural distribution in Jeju Island, have originated from a single maternal origin and differences in morphological and genetic backgrounds form those of Korean Peninsula and the other countries, and had probably immigrated via Korean Peninsula. These findings will contribute as basic information for understanding the migration history and biogeographic relationship of mammals on Jeju Island in East Asia.

• Pediatric Infection and Vaccine
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• v.17 no.1
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• pp.16-22
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• 2010

Purpose : We aimed to investigate the clinical and phylogenetic characteristics of Escherichia coli Urinary Tract Infections (E. coli UTI). Methods : We enrolled patients with culture-proven E. coli UTI, who were admitted at the study hospital from September 2008 to August 2009. We investigated clinical data of patients with E. coli UTI and characteristics of isolated E. coli strains. The phylogenetic groups were classified using triplex polymerase chain reaction (PCR), and the distribution of nine virulent genes was determined by multiplex PCR. Results : A total of 47 patients have participated in this study. Thirty (63.8%) were under 6 months; eight (17.0%) were between 6-12 months; and nine (19.1%) were over 12 months. We compared two age groups between under 6-month and over 6-month. In the age group under 6-month, higher proportion of male (P =0.002) and group B2 strains (P =0.020) were observed. In contrast, higher proportion of female and group non-B2 strains were observed in age group over 6-month. Frequencies of papC, papGII, papGIII, sfa/foc, hlyC, cnf1, fyuA, iroN and iucC were estimated as 68.1%, 57.4%, 42.6%, 46.8%, 46.8%, 31.9%, 87.2%, 48.9% and 63.8%, respectively. In the comparison of phylogenetic groups, group B2 showed higher distribution of virulent genes, while group D included more strains resistant to trimethoprim/sulfamethoxazole (TMP/SMZ) than other groups. Conclusion : We showed the age group-specific difference in the distribution of sex ratios and phylogenetic groups; more male and group B2 strains in age group under 6-month, while more female and group non-B2 in age group over 6-month. However, further evaluation including larger number of patients will be necessary to confirm above thesis in future molecular epidemiological studies.

• Korean Journal of Veterinary Research
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• v.12 no.1
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• pp.37-50
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• 1972

Another comparison of alveolar gas pressures, in a continuously rebreathing dog lung, with pulmonary arterial (mixed venous) blood, again showed alveolar pressures to be the higher for $CO_2$ and usually $O_2$ (positive ${\Delta}Pco_2$, and ${\Delta}Po_2$). ${\Delta}Pco_2$ was almost invariably positive, it was independant of time and of plasma pH changes produced by acid or bicarbonate infusion, but proportional to blood $CO_2$ level. It was seemingly little affected by the distribution or magnitude of blood flow nor did it result from failure of $CO_2$ equilibrium within the blood, but it did rise with carbonic anhydrase inhibition. ${\Delta}Po_2$ was more variable and sometimes negative, particularly at low blood flow rates. It seemed in dependant of time, and plasma pH changes, apart from an inverse relationship with that resulting from $CO_2$ changes. It existed despite considerable potential for gas exchange, and was unaffected by inhibition of the $CO_2$ reactions.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.29 no.2
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• pp.141-148
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• 2016

The long-span bridges such as Incheon Bridge and Seohae Grand Bridge are located on the coastal region effected frequently by strong wind of typhoons. In order to ensure the wind-resistant performance of the structure, estimation of the proper design wind speed is very important. In this study, stochastic estimation of design wind speed incurred by typhoons is carried out. For this purpose, we first established probability distribution of climatological parameters such as central pressure depth, distance of closest approach, translation speed and heading to build statistical model of typhoons, which are employed in Monte Carlo simulation for hypothetical typhoons. Once a typhoon is generated with statistically justified parameters, wind speeds are estimated along its path using wind field model. Thousands of typhoons are generated and their peak wind speeds are utilized to establish the extreme wind speeds for different return period. The results are compared with design basic wind speeds in Korean Highway Bridge Design Code, showing that the present results agree well with similar studies while the existing code suggests higher design wind speed.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8413-8422
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• 2014

Background: To investigate the relationship of five TP53 polymorphisms (p.P47S, p.R72P, PIN3 ins16bp, p.R213R and r.13494g>a) with the esophageal cancer (EC) risk in North Indians. Materials and Methods: Genotyping of p.P47S, p.R72P, PIN3 ins16bp, p.R213R and r.13494g>a polymorphisms of TP53 in 136 sporadic EC patients and 136 controls using polymerase chain reaction and PCR-RFLP. Results: The frequencies of genotype RR, RP and PP of p.R72P polymorphism were 16.91 vs 26.47%, 58.82 vs 49.27% and 24.27 vs 24.27% among patients and controls respectively. We observed significantly increased frequency of RP genotype in cases as compared to controls (OR=1.87, 95% CI, 1.01-3.46, p=0.05). The frequencies of genotype A1A1, A1A2 and A2A2 of PIN3 ins16bp polymorphism were 69.12 vs 70.59%, 27.20 vs 25% and 3.68 vs 4.41% among patients and controls. There was no significant difference among genotype and allele distribution between patients and controls. The frequencies of genotype GG, GA and AA of r.13494g>a polymorphism were 62.50 vs 64.70%, 34.56 vs 30.15% and 2.94 vs 5.15% among patients and controls respectively. No significant difference between genotype and allele frequency was observed in the patients and controls. For p.P47S and p.R213R polymorphisms, all the cases and controls had homozygous wild type genotype. The RP-A1A1-GG genotype combination shows significant risk for EC (OR=2.01, 95%CI: 1.01-3.99, p=0.05). Conclusions: Among the five TP53 polymorphisms investigated, only p.R72P polymorphism may contributes to EC susceptibility.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.39 no.6
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• pp.713-723
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• 2019

Due to the climate change and various rainfall pattern, it is difficult to estimate a rainfall criterion which cause inundation for urban drainage districts. It is necessary to examine the result of inundation analysis by considering the detailed topography of the watershed, drainage system, and various rainfall scenarios. In this study, various rainfall scenarios were considered with the probabilistic rainfall and Huff's time distribution method in order to identify the rainfall characteristics affecting the inundation of the Hyoja drainage basin. Flood analysis was performed with SWMM and two-dimensional inundation analysis model and the parameters of SWMM were optimized with flood trace map and GA (Genetic Algorithm). By linking SWMM and two-dimensional flood analysis model, the fitness ratio between the existing flood trace and simulated inundation map turned out to be 73.6 %. The occurrence of inundation according to each rainfall scenario was identified, and the rainfall criterion could be estimated through the logistic regression method. By reflecting the results of one/two dimensional flood analysis, and AWS/ASOS data during 2010~2018, the rainfall criteria for inundation occurrence were estimated as 72.04 mm, 146.83 mm, 203.06 mm in 1, 2 and 3 hr of rainfall duration repectively. The rainfall criterion could be re-estimated through input of continuously observed rainfall data. The methodology presented in this study is expected to provide a quantitative rainfall criterion for urban drainage area, and the basic data for flood warning and evacuation plan.

• Horticultural Science & Technology
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• v.17 no.3
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• pp.329-332
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• 1999

The objective of this study was to determine the influence of grafting timing, rootstock cut timing and leaf removal with promalin ($GA_{4+7}+BA$) treatments on the maiden tree growth, lateral development and flower bud initiation. In mid-March 1997, two-year-old M.9-T337 rootstocks selected with trunk diameter over 1 cm were planted in the field. Chip budding with 'Fuji' scion on M.9-T337 rootstock budded in mid-April was earlier in sprouting than chip budding in mid-June. Late cutting chip budding (LCCB) with 'Fuji' scion on M.9-T337 rootstock was lower in the failed budding percentage with 14% than that of early cutting chip budding (ECCB). Especially, ECCB in April was not suitable for scion growth such as uniformity with high percentage of failed tree. Grafting timing in mid-June and rootstock cutting timing of LCCB induced more branches and flower buds than other treatments. Removal of 8 to 10 uppermost immature leaves on central leader stem and application of Promalin 250 mg/L after every 30 cm of terminal growth produced a 189 cm tall tree with 9 flower buds and 14.2 short lateral shoot from 30 to 35 cm long in length in 1998. Promalin increased branching on second-season growth and, when combined with leaf removal, resulted in uniform distribution of branches along the central leader stem.

• Polymer(Korea)
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• v.25 no.6
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• pp.855-865
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• 2001

The optimization condition of injection molding for a commercial product of TV speaker grille of A Company was induced using a CAE software of Moldflow. The flow and packing phase analysis was performed by using flow balance, runner balance, and the intermediate one by using the above two balances, which were used for controlling the amount of packing resins into the cavity, Later, the analysis performed by using the measured viscosity (local database) at various shear rates and the results were compared with the computer simulation using the standard database. Flow balance induced minimized weld line resulted in a better appearance and physical properties of the were line, but exhibited a disadvantage of large deformation and gas formation due to over-packing of the molten resin in the center of the speaker grille. Runner balance improved the disadvantage of the flow balance by controlling the amount of molten resin injected from the gate, however resulted reduced mechanical properties and poor appearance of the weld line. However, the modified method induced from the flow and runner balance improved the disadvantages by changing the runner size. In addition, the analyses based on the local database and the standard database were compared. Although the measured viscosity was slightly higher and the temperature distribution was broader than the standard database, no distinct difference was obtained from the analysis using the two different databases.

• Journal of the Earthquake Engineering Society of Korea
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• v.11 no.1 s.53
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• pp.11-19
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• 2007

This paper proposes an optimal design method of distribution and capacities of linear viscous dampers for vibration control of two adjacent buildings. The previous researches have dealt with suboptimal design problem under the assumption that linear viscous dampers are distributed uniformly or proportionally to the sensitivity of the modal damping ratio according to floors, whereas this study deals with global optimization problem in which the damping capacities of each floor are independently selected as design parameters. For this purpose, genetic algorithm to effectively search multiple design variables in large searching domains is adopted and objective function leading to the global optimal solutions is established through the comparison of several optimal design values obtained from different objective functions with control performance and damping capacity. The effectiveness of the proposed method is investigated by comparing the control performance and total damping capacity designed by the proposed method with those of the previous method. In addition, the time history analyses are performed by using three historical earthquakes with different frequency contents, and the simulation results demonstrate that the proposed method is an effective seismic design method for the vibration control of the adjacent structures.