• Title/Summary/Keyword: GT-60

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Investigation of the Cause of High Vibration in a Low Pressure Turbine Casing with Manufacturing Defects by Frequency Response Analysis (주파수 응답해석을 통한 제작공차를 가지는 저압터빈 케이싱의 고진동 원인 규명)

  • Youn, Hee-Chul;Woo, Chang-Ki;Hwang, Jai-Kon
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.24 no.4
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    • pp.463-468
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    • 2015
  • High vibration of a low pressure (LP) turbine casing caused safety problems and life at the facility it was housed in. The main focus of this study was the cause of the high vibration in a low pressure turbine casing with manufacturing defects by frequency response analysis, compared with the results of experiments. Therefore, excited accelerations were obtained from the LP casing fundamental, and frequency responses were analyzed. The measurement and the modal analysis showed that the natural frequency of the LP turbine casing was 61.26 Hz and the excited frequency of the turbine rotor was 60.25 Hz. The manufacturing defect caused a decrease in the casing natural frequency and resulted in the high vibration of the casing because it moved close to the resonant frequency.

Effects of Photoperiod Manipulation on Gonadal Activity of the Damselfish, Chromis notata

  • Lee, Chi-Hoon;Park, Young-Ju;Lee, Young-Don
    • Development and Reproduction
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    • v.21 no.2
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    • pp.223-228
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    • 2017
  • This study investigated the effect of different photoperiods (14L: 10D, 12L:12D and 10L:14D) on the gonadal development and GtH mRNA expression in the pituitary of damselfish. The results showed that gonadosomatic index (GSI) was significantly lower in shot photoperiod (10L:14D), in comparison with other photoperiodic group during the spawning season. After 60 days treatment, histological analysis of gonad tissue showed that the gonad of 10L:14D and 12L: 12D treatment groups were resting phase with spermatogonia and perinucleolus stage oocytes but the gonad of 14L:10D treatment group was still ripe phase with spermatozoa and mature stage oocyte. The $FSH{\beta}$ and $LH{\beta}$ mRNA expression in pituitary drastically decreased shot photoperiod treatment from July (spawning period). These results suggest that photoperiod is considered to be the most effective environmental factor in controlling the reproductive cycle of damselfish.

On the Hull Vibration of the Training Ship Sae-Ba-Da (실습선 새바다호의 선체진동에 관하여)

  • Park, Jung-Hui
    • Journal of Korea Fishing Vessel Association
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    • v.29
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    • pp.15-20
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    • 1986
  • This paper describes on the measurement of the deck vibration produced by the main engine vibration of stern trawler MIS SAE-BA-DA (2,275GT, 3,600PS) while the ship is cruising and drifting. The obtained results are as follows; 1. The deck vibration level was the highest point at vertical line which pass main engine and the lowest point at vertical line which pass top bridge while the crusing. 2. The vibration source level of the main engine, screw shaft and screw propeller were respectively 110, 90 and 80% while the crusing. 3. The main deck vibration pressure level at the check points 2, 20, 30, 40, 60, 70, 80, 86m from the bow to stern was respectively 9, 8, 7, 10, 22, 45, 18, 23%. 4. The frequency distributions of the main engine, screw shaft, screw propeller vibration were from 3Hz to 10KHz, predominant frequency was 1KHz, each vibration accelration the highest level were respectively 1.3, 0.8, 0.5mm/$S^2$. 5. The predominant frequency distributions of the main deck, second deck, bridge deck and top bridge deck's vibration were from 10 to 30Hz, and each vibration accelration level were respe¬ctively 0.7, 0.05, 0.07, 0.04mm/$S^2$.

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Different RAPD patterns between Metagonimus yokogawai and Metagonimus Miyata type (RAPD분석을 이용한 요코가와 흡충과 미야타흡충의 분자생물학적 비교)

  • Yu, Jae-Ran;Jeong, Jin-Seong;Chae, Jong-Il
    • Parasites, Hosts and Diseases
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    • v.35 no.4
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    • pp.295-298
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    • 1997
  • Genonlic DNA from Metagonimn vokogawci and Metagonimw Miyata type was amplified by polymerase chain reaction based on the random amplification of polymorphic DNA (RAPDI technique. Eight random 10-mer oligonucleotide primers (OPA-02, 5-TGCCGAGCTG-3; OPA-09, 5-GGGTAACGCC-3; OPA-17, 5-GTGATCGCAG-3; OPA-11, 5-CAATCGCCGT-3; OPA-13, 5-CAGCACCCAC-3; OPA-17. 5-GACCGCTrGT-3; OPA-19, 5-CAAACGTCGG-3; OPA-20, 5-GTTGCGATCC-3) WITH A G+C CONTENT FO 60-70% (Kit A. Operon Technologies Inc., California, USAI could produce distinguishable banding patterns between the two Metngonimus species. From the results of this study, it was suggested that Metcsonimus Miyata type has a different DNA sequence from M. WOkQgGUIGi. Key words: Metcgonimw vokognwai, MetnBonimw Miyata type, random amplification of polymorphic DNA (RAPD)

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ABCB1 Polymorphisms and Imatinib Response in Chronic Myeloid Leukemia Patients: A Systematic Review and Meta-analysis (ABCB1 유전적 다형성이 만성 골수성 백혈병 환자의 Imatinib 치료 반응에 미치는 영향: 체계적 문헌고찰 및 메타분석)

  • Ha, Hye Min;Chun, Pusoon
    • YAKHAK HOEJI
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    • v.60 no.3
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    • pp.118-127
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    • 2016
  • A growing number of studies have demonstrated that ABCB1 gene polymorphisms are associated with the variability of responses to imatinib. However, the effects of ABCB1 polymorphisms on imatinib response in chronic myeloid leukemia (CML) are inconsistent. The aim of the present study was to clarify the associations between ABCB1 polymorphisms and imatinib response in CML. A systematic literature review was performed. The databases of PubMed, Embase, and Cochrane Library were searched for all published studies from inception to December 2015. The following terms were used with functions of 'AND' and 'OR': 'chronic myeloid leukemia', 'CML', 'ABCB1', 'MDR1', 'polymorphism', 'SNP', and 'imatinib'. Using the Review Manager 5, odds ratios (ORs) were pooled to estimate the effect of ABCB1 polymorphisms on imatinib response in CML. The pooled analysis showed that ABCB1 2677 G allele was significantly associated with poor response to imatinib in African and Asian patients (GG vs TT, OR: 0.32, p<0.0001; GG+GT vs TT, OR: 0.44, p=0.0005). In subgroup analyses, African patients carrying ABCB1 1236 C allele exhibited higher risk for worse response, whereas Asian patients with 1236 C allele showed better response (CC+CT vs TT, OR: 0.41, p=0.008 for African; OR: 1.65, p=0.03 for Asian). There was no association between C3435T polymorphisms and imatinib response in African, Asian, and Caucasian CML patients.

Association of 8q24.21 rs10505477-rs6983267 Haplotype and Age at Diagnosis of Colorectal Cancer

  • Haerian, Monir Sadat;Haerian, Batoul Sadat;Rooki, Hassan;Molanaei, Saadat;Kosari, Farid;Obohhat, Maedeh;Hosseinpour, Parisa;Azimzadeh, Pedram;Mohebbi, Seyed Reza;Akbari, Zahra;Zali, Mohammad Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.369-374
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    • 2014
  • Background: Colorectal cancer (CRC) is the fourth most common cause of cancer death in the world. Genetic variants in 8q24.21 including rs10505477 and rs6983267 have been hypothesized to be involved in susceptibility to CRC. This study aims to investigate the possible association between these loci and their haplotypes with CRC risk in Iranian population. Materials and Methods: Subjects were recruited from two hospitals in Tehran. The rs10505477 and rs6983267 polymorphisms were genotyped by TaqMan real time PCR using subject genomic DNA, extracted either from formalin-fixed, paraffin-embedded tissue of patients or from blood of the controls by standard methods. Results: A total of 715 subjects (380 CRC patients and 335 matched controls) were genotyped in this study. Allele and genotype analysis of the rs10505477 and rs6983267 polymorphisms by gender, age at diagnosis, tumor location, tumor grade, and tumor node metastasis (TNM) showed no significant association with CRC risk. There was a significant relationship between GG haplotype and susceptibility to age at diagnosis for both <60 and ${\geq}60$ (p=0.0005 and p=0.000004, respectively) and between GT and CRC in the age at diagnosis ${\geq}60$ (Table 3: p=0.031). The GG haplotype was less frequent in CRC patients with the age at diagnosis <60, but was more common in subjects with the age at diagnosis ${\geq}60$. Conclusions: Results of this study suggests that the rs6983267 and rs10505477 polymorphisms alone may not be relevant to CRC risk, but their GG haplotype plays a notable role in age at diagnosis of CRC in the Iranian population.

Fishing Experiment for Development of Unused Fishery Resources on the Deep Sea Bed of Korean East Sea (동해구 심해 미이용 자원의 어획 시험 연구)

  • Lee, Byoung-Gee;Lee, Ju-Hee;Shin, Hyeong-Il
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.22 no.4
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    • pp.61-70
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    • 1986
  • In accordance with a rapid growth of demani on aquatic animals, researches of the unused fishery resources On the deep sea b~d in the Korean Waters has been and will be required. The authors carried out a series of fishing experiments to investigate the available resources and to find the effective fishing method on the deep sea bed of the Korean East Sea. In the experiments, 19 kinds of traps which are different from each other in shape, mesh size and entrance diameter were used. The fishing experiments w~r;; carried out in four areas of 20Dm, 600.'11, 800m and 1000.'11 deep respectively, by the Pusan 402 (30:) GT) and the Pusan 403 (279GT), the training ships of National Fisheries University of Pusan, during August, 1986. The catc~ were analyzed with the size, the depth and the construction of traps. The results obtained can be summarized as follows: 1. Main species of the catch w~re pink shrimp, Pandalus bolelis, a kind of welks, Buccimum striatissimum and a kind of larg~ crabs. Chiono8cetes japonicus and the another species were few. 2. The CPUE value (expressed by the number of catch per trap in this paper) of pink shrimp was the highest in the depth of 20J-n around, and the value in the depth of 600.'11 or more decreased gradually with an increase of the depth. But, the value of Buccimum straitissimum was much higher in the depth of 6:J:)!1I or more than that in the depth of 200m around. On the other hand, the value of Chion:Jecetes japonjcus was very low in general. 3. The iniividual body size of the catch differed with the depth. Pink shrimps caught in the depth of 200m around were smaller than those in the depth of 600.'11 or more. In contrast with this, Baccimum striatissim:t.m caught in the depth of 200m around were larger than those in the depth of 600.'11 or more. 4. Depending on the selection curve in Ishida's method for the mesh size of trap webbing, the carapace length of pink shrimp and the shell length of Buccimum striatissimum which are equivalent to 100% relative catching efficiency can be estimated about 3.5cm and 6.5cm or so respectively. 5. The number of catch of pink shrimp and Buccimum striatissimum by the 60.'1'1.'11 entrance diameter of trap were less than that by the 90mm, 120mm and 150mm, even thogh the diffierence am~r, g 9:Jmm, 120.'11.'11 and 150:1'.'11 are not so large.

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REPLACEMENT OF POSTERIOR RESTORATIONS (구치부 수복물의 재수복에 관한 연구)

  • Kim, Ji-Young;Choi, Kyoung-Kyu;Park, Sang-Jin
    • Restorative Dentistry and Endodontics
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    • v.31 no.6
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    • pp.460-469
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    • 2006
  • This article complies a survey on the replacement of the posterior restorations and accesses possible factors that influence the replacement of posterior restorations. The data was collected from patients that visited department of conservative dentistry from Dec 1st 2003, to Sep 3rd 2004. Teeth was restricted to posterior permanent teeth. 9 dentists recorded age, gender of patients, tooth location, cavity farm and restorative material. They rated marginal adaptation, anatomic form, secondary caries of old restoration by modified Ryge criteria system. The statistical analysis was performed with Chi square test (p < 0.05) for replacement ratio according to patients, tooth factor and One way ANOVA was performed for comparison of old restoration according to restorative material. The results were as follows; 1. The female (62%) was statistically higher ratio than the male (38%). 2. The distribution of replacement case according to age, the rate of replacement was in descending order, 20's (38.3%), 40's (16.8%), 30's (15.9%), 10's (11.1%), 50's (9.2%), 60's (8.7%). 3. The rate of replacement was 88% for molar and 12% for premolar (p $gt; 0.05). 4. The rate of replacement was 39% for maxillar and 61% for mandible (p $gt; 0.05). 5. The material of restorations was amalgam (69%), gold inlay (17%), composite resin (13%). 6. In rating system by modified Ryge criteria system on margin adaptation, there was statistically significant difference between amalgam and gold inlay. But on anatomic form and caries, there was no statistically significant difference among the material of restorations.

Energy expenditure of physical activity in Korean adults and assessment of accelerometer accuracy by gender (성인의 13가지 신체활동의 에너지 소비량 및 가속도계 정확성의 남녀비교)

  • Choi, Yeon-jung;Ju, Mun-jeong;Park, Jung-hye;Park, Jong-hoon;Kim, Eun-kyung
    • Journal of Nutrition and Health
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    • v.50 no.6
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    • pp.552-564
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    • 2017
  • Purpose: The purpose of this study was to measure energy expenditure (EE) the metabolic equivalents (METs) of 13 common physical activities by using a portable telemetry gas exchange system ($K4b^2$) and to assess the accuracy of the accelerometer (Actigraph $GT3X^+$) by gender in Korean adults. Methods: A total of 109 adults (54 males, 55 females) with normal BMI (body mass index) participated in this study. EE and METs of 13 selected activities were simultaneously measured by the $K4b^2$ portable indirect calorimeter and predicted by the $GT3X^+$ Actigraph accelerometer. The accuracy of the accelerometer was assessed by comparing the predicted with the measured EE and METs. Results: EE (kcal/kg/hr) and METs of treadmill walking (3.2 km/h, 4.8 km/h and 5.6 km/h) and running (6.4 km/h) were significantly higher in female than in male participants (p < 0.05). On the other hand, the accelerometer significantly underestimated the EE and METs for all activities except descending stairs, moderate walking, and fast walking in males as well as descending stairs in females. Low intensity activities had the highest rate of accurate classifications (88.3% in males and 91.3% females), whereas vigorous intensity activities had the lowest rate of accurate classifications (43.6% in males and 27.7% in females). Across all activities, the rate of accurate classification was significantly higher in males than in females (75.2% and 58.3% respectively, p < 0.01). Error between the accelerometer and $K4b^2$ was smaller in males than in females, and EE and METs were more accurately estimated during treadmill activities than other activities in both males and females. Conclusion: The accelerometer underestimated EE and METs across various activities in Korean adults. In addition, there appears to be a gender difference in the rate of accurate accelerometer classification of activities according to intensity. Our results indicate the need to develop new accelerometer equations for this population, and gender differences should be considered.

Effects of Omija (Schizandra chinensis Baillon) Concentrate on Blood Alcohol Clearance and Hepatoprotective Function in Rats Induced by Acute Ethanol Intoxication and Chronic Ethanol Treatment (오미자농축액이 급성주정중독량 및 장기간 주정을 투여한 흰쥐의 혈중 알코올 분해율과 간 기능 보호에 미치는 영향)

  • Han, Chan-Kyu;Seong, Ki-Seung;Lee, Kyung-Won;Park, Sung-Sun;Jeong, Ji-Yun;Kim, Sung-Soo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.8
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    • pp.1139-1147
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    • 2014
  • We investigated whether or not Schisandra chinensis (SC), a traditional herbal medicine, has protective effects against alcohol-induced fatty liver and blood alcohol clearance. Two tests focused on acute intoxication and chronic ethanol treatment were carried out. For the chronic ethanol treatment test, rats were fed ethanol by intragastric administration everyday for 8 weeks to induce alcoholic fatty liver. Ethanol treatment significantly increased blood alcohol concentration at 90 min after acute ethanol intoxication. Compared with the two ethanol-treated groups, rats administered ethanol along with SC extracts showed an approximately 13% increased blood alcohol clearance rate at 360 min. Chronic ethanol treatment significantly increased serum and hepatic triglyceride (TG) levels, and caused fatty degeneration of liver. Ethanol treatment also elevated the serum total-cholesterol (TC) level. However, after feeding of ethanol plus SC extracts, ethanol-induced elevation of hepatic TG levels reversed, whereas elevation of serum TG and TC levels was not observed after treatment with SC extracts. Ethanol treatment significantly increased ${\gamma}$-GT, aspartate aminotransferase, and alanine aminotransferase activities after 8 weeks. Compared with the ethanol-fed group, rats administered ethanol plus SC extracts for 4 weeks showed attenuated fatty degeneration as well as decreased hepatic function test values. SC administration also significantly increased intracellular lipid accumulation in hepatocytes and reduced steatosis score and hepatic TG levels, as measured by biochemical and histolopathological analyses. Our results indicate that the protective effects of SC are accompanied by a significant decrease in hepatic TG levels, thereby suggesting SC has the ability to prevent ethanol-induced fatty liver, by reducing hepatic TG and enzyme levels in alcoholic rats.