• Title/Summary/Keyword: GRC

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Correlation between the Content and Pharmacokinetics of Ginsenosides from Four Different Preparation of Panax Ginseng C.A. Meyer in Rats

  • Jeon, Ji-Hyeon;Lee, Jaehyeok;Lee, Chul Haeng;Choi, Min-Koo;Song, Im-Sook
    • Mass Spectrometry Letters
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    • v.12 no.1
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    • pp.16-20
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    • 2021
  • We aimed to compare the content of ginsenosides and the pharmacokinetics after the oral administration of four different ginseng products at a dose of 1 g/kg in rats. The four different ginseng products were fresh ginseng extract, red ginseng extract, white ginseng extract, and saponin enriched white ginseng extract prepared from the radix of Panax ginseng C.A. Meyer. The ginsenoside concentrations in the ginseng product and the rat plasma samples were determined using a liquid chromatography-tandem mass spectrometry (LC-MS/MS). Eight or nine ginsenosides of the 15 tested ginsenosides were detected; however, the content and total ginsenosides varied depending on the preparation method. Moreover, the content of triglycosylated ginsenosides was higher than that of diglycosylated ginsenosides, and deglycosylated ginsenosides were not present in any preparation. After the single oral administrations of four different ginseng products in rats, only four ginsenosides, such as 20(S)-ginsenosides Rb1 (GRb1), GRb2, GRc, and GRd, were detected in the rat plasma samples among the 15 ginsenosides tested. The plasma concentrations of GRb1, GRb2, GRc, and GRd were different depends on the preparation method but pharmacokinetic features of the four ginseng products were similar. In conclusion, a good correlation between the area under the concentration curve and the content of GRb1, GRb2, and GRc, but not GRd, in the ginseng products was identified and it might be the result of their higher content and intestinal biotransformation of the ginseng product.

Study on the Polymer Gel Fiber of Alkali Resistance Zirconia System for GRC (GRC 제조용 내알칼리성 지르코니아계 고분자 겔섬유에 관한 연구)

  • 신대용;한상목;김경남;강위수
    • Journal of the Korean Ceramic Society
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    • v.31 no.8
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    • pp.934-940
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    • 1994
  • Fibers of ZrO2-SiO2 system were prepared from the hydrolysis and condensation of Si(OC2H5)4 and Zr(OnC3H7)4 with different H2O/alkoxide molar ratios. It was found that fibers could be drawn in the viscosity range of 1~100 poise from HCl catalyzed solutions with lower water contents of the mole ratio H2O/alkoxide, r 2. The fibrous gels were converted into the corresponding oxide glass fibers by heating at 80$0^{\circ}C$. Mechanical test was performed on E, A and 20ZrO2-80SiO2 glass fibers reinforced cement in order to investigate the flexural strength. The flexural strength value of 20ZrO2-80SiO2 glass fibers reinforced cement was greater than those of E and A. The chemical durability of the fibers in alkaline solutions increased with ZrO2 content. The weight loss due to the corrosion by 2N-NaOH solutions at $25^{\circ}C$ for 160 hours was about 0.31$\times$10-2 mg/dm2 for the 20ZrO2-80SiO2 glass fibers, which was superior to that of Vycor glass.

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Application of FRF-Based Substructuring to Optimization of Interior Noise in Vehicle (실차 소음 최적화를 위한 주파수 응답 함수 합성법의 적용)

  • Jung, Won-Tae;Kang, Yeon-June;Kim, Sang-Hoon
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.11b
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    • pp.140-143
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    • 2005
  • The hybrid CAE/CAT methods are widely applied to product development in various fields because this method can predict the response of the whole system when a part of the system is changed. Especially, the hybrid CAE/CAT method is very useful to predict tile vehicle NVH characteristics after changing some parts of the vehicle. Target parts can be established on the basis of test models and FE models of the prototype constructed in the planning stage of car development. In this study, the topic was focused on the proper test-based FBS application process to predict vehicle NVH characteristic. First, the test-based FBS method was apply to vehicle substructure and car-body. And then the test-based model was replaced with FE model to apply hybrid CAE/CAT method. The replaced FE model was modified through the optimization process. The interior noise in vehicle during the drive was predicted with Modified FE model, then the predicted results were verified by experimenting with actual modified model.

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A Study On Vehicle Interior Noise Reduction Applying FRF Based Substructuring (주파수 응답함수 합성법을 이용한 차량 실내 소음 저감에 관한 연구)

  • Oh, Sang-Hoon;Kang, Yeon-June;Sun, Jong-Cheon;Song, Moon-Sung;Kim, Seong-Goo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.05a
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    • pp.122-125
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    • 2006
  • The Substructure Synthesis means the technology to predict the dynamic properties of an assembly from the properties of its components, or to predict the effect of a modification on a structure. The FRF Based Substructuring method is a kind of the Substructure Synthesis and very useful to predict the efficiency of the product in the early stage of development. Especially, the Hybrid FBS method is very useful to predict the vehicle NVH characteristics after modifying some components of the vehicle. Target components can be established on the basis of test models and FE models of the prototype constructed in the early stage of development. In this study, the Hybrid FBS method was applied to vehicle subframe and car-body in order to reduce vehicle interior noise induced by engine exciting force.

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A simple prediction procedure of strain-softening surrounding rock for a circular opening

  • Wang, Feng;Zou, Jin-Feng
    • Geomechanics and Engineering
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    • v.16 no.6
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    • pp.619-626
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    • 2018
  • A simple prediction procedure was investigated for calculating the stresses and displacements of a circular opening. Unlike existed approaches, the proposed approach starts each step with a radius increment. The stress for each annulus could be obtained analytically, while strain increments for each step can be determinate numerically from the compatility equation by finite difference approximation, flow rule and Hooke's law. In the successive manner, the distributions of stresses and displacements could be found. It should be noted that the finial radial stress and displacement were equal to the internal supporting pressure and deformation at the tunnel wall, respectively. By assuming different plastic radii, GRC and the evolution curve of plastic radii and internal supporting pressures could be obtained conveniently. Then the real plastic radius can be calculated by using linear interpolation in the evolution curve. Some numerical and engineering examples were performed to demonstrate the accuracy and validity for the proposed procedure. The comparisons results show that the proposed procedure was faster than that in Lee and Pietrucszczak (2008). The influence of annulus number and dilation on the accuracy of solutions was also investigated. Results show that the larger the annulus number was, the more accurate the solutions were. Solutions in Park et al. (2008) were significantly influenced by dilation.

Genetic Expression of Color Approved by Color Qualities of Munsell System on the Cocoon of Silkworm, Bombyx mori (누에 고치색 유전자 발현의 다양성 검정 및 색채과학적 해석)

  • Han, Myung-Sae;Park, Hyun-Ro;Han, Sang-Mi;Nam, Ki-Soo;Kwon, Soon-Ha;Lim, Jong-Sung;Nguyen, Mau Tuan
    • Journal of Sericultural and Entomological Science
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    • v.41 no.1
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    • pp.20-28
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    • 1999
  • Color qualities investigated on the basis of Munsell code and Korean standard color code for the cocoons from various strain of mulberry silkworm, Bombyx mori. 16 of different color qualities were identified from 21 of original silworm strains, and determinated international name with the revision of Korean color name for cocoon. The various cocoon color confirmed on the sphere from 567 to 593 nm wavelength, 78% of those located at the region about 580 nm (575~584) of sensitive "color difference limen". Y gene engaged broad ranges of wavelength (575~593 nm) in the color expression, by contrast with other genes of Pk (593 nm), F (584~593), Grc and relative G group (567~570 nm), on the transmission of carotenoid or flavonoid color substance. YC gene expression by original silk worm strain was also distinguished by those variation of specific yellow than other colors from Grc, GaGb, Gc, and YPkF. Appearance of chrome yellow cocoon was dominant than other yellow in the cross among vivid yellow group. F1 of pin${\times}$green produced the cocoon of yellow such as "additive mixture" as color light, however, most of the hybrid between yellow cocoon showed the color similar to "subtractive mixture" as a mixture of dyestuff. Hybrid cocoons among yellow or green colors were decreased their hue, value, and chroma, than those of parent. Diallel cross among the strain of various green cocoon suggest the existence of Grc, Ga, Gb, Gc genes. Cream colored cocoon of B. mandarina was differed from other yellow cocoon of Bobyx mori B. mori. Y$^A$ with Ymc showed the similar role of Y with C, therefore, segregated yellow cocoon from the B. mori${\times}$B. mandarina (+$^YC/Y^AYmc$). YC expression of $Y^AY$mc genes might be suppressed by deficiency of outer layer sericin on the middle division of silk giand in the B. mandarina.

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ON THE IDENTITIES OF BOL-MOUFANG TYPE

  • Solarin, A.R.T.
    • Kyungpook Mathematical Journal
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    • v.28 no.1
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    • pp.51-62
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    • 1988
  • In this work we study properties of five identities of Bol-Moufang type (1). We establish a necessary and sufficient condition for a loop to be an RC-loop. A corollary to this is the condition for a Bol loop to be an RC-loop. Some proerties of a generalization of RC-loops are discussed. We also state the relationship between the supernucleus M(G) of a loop G and the nucleii of loops which do not have the inverse property. Finally, we give two tables of non-associative RC-loops of order 16, which are not Bol loops.

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Problems and Improvement of Privacy Impact Assessment (개인정보영향평가의 문제점과 개선방안)

  • Choi, Young-hee;Han, Keun-hee
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.26 no.4
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    • pp.973-983
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    • 2016
  • It's been almost 6 years since PIA was implemented based on legislation. So I analyzed problems of PIA from the perspective of ITSM 3 elements. I mainly took account of quality improvement of the report when I assessed systems processing personal informations. So, I propose in terms of logical validity improvement of assessment report. The improvements on 4 different outputs for each phase are many cases that I assessed systems processing personal informations. And I propose improvements on qualified assessors having capability of GRC and on process for managing the assessment system. To settle down PIA system as the reasonable and effective assessment system even after 2016, the statutory deadline for completion of PIA, assessors and appointed assessment firms and authorities should cooperate to complete the assessment system.

Radio Resource Management using a Game Theoretic Approach Method in Heterogeneous Wireless Networks (이종 네트워크 환경에서 게임 이론적 접근방법을 이용한 무선 자원관리)

  • Kim, Nam-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.3
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    • pp.2178-2184
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    • 2015
  • With the development of wireless network technologies, mobile users may use various networks easily and expect more advanced services. On the other hand, it may bring on some problems with network resource management that should lead the service provider to improve the current service quality and manage the network resource efficiently. This paper proposes the optimized radio resource management (RRM) scheme that integrates the Grey Relational Analysis (GRA) and game theory. The first applies the GRA to determine the Grey Relation Coefficient (GRC) factors that represent the network preference, and the network provider then selects the requested service that provide maximum payoff through Nash Equilibrium. Six requested services that have one application service among four different types of service classes were considered and the game was played repeatedly. In WiMAX, WLAN 1 and WLAN 2 game, the maximum payoff of each players was 93, 90.6 and 92.8 respectively. The experimental results show that every requested service can be selected by the network provider. Consequently, the proposed radio resource management mechanism is more effective in heterogeneous wireless networks.

FER Performance Evaluation and Enhancement of IEEE 802.11 a/g/p WLAN over Multipath Fading Channels in GNU Radio and USRP N200 Environment

  • Alam, Muhammad Morshed;Islam, Mohammad Rakibul;Arafat, Muhammad Yeasir;Ahmed, Feroz
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.12 no.1
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    • pp.178-203
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    • 2018
  • In this paper, authors have been evaluated the Frame Error Rate (FER) performance of IEEE 802.11 a/g/p standard 5 GHz frequency band WLAN over Rayleigh and Rician distributed fading channels in presence of Additive White Gaussian Noise (AWGN). Orthogonal Frequency Division Multiplexing (OFDM) based transceiver is implemented by using real-time signal processing frameworks (IEEE 802.11 Blocks) in GNU Radio Companion (GRC) and Ettus USRP N200 is used to process the symbol over the wireless radio channel. The FER is calculated for each sub-carrier conventional modulation schemes used by OFDM such as BPSK, QPSK, 16, 64-QAM with different punctuated coding rates. More precise SNR is computed by modifying the SNR calculation process of YANS and NIST error rate model to estimate more accurate FER. Here, real-time signal constellations, OFDM signal spectrums etc. are also observed to find the effect of multipath propagation of signals through flat and frequency selective fading channels. To reduce the error rate due to the multipath fading effect and Doppler shifting, channel estimation (CE) and equalization techniques such as Least Square (LS) and training based adaptive Least Mean Square (LMS) algorithm are applied in the receiver. The simulation work is practically verified at GRC by turning into a pair of Software Define Radio (SDR) as a simultaneous transceiver.