• Title/Summary/Keyword: GQ

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Overlap syndrome of Miller-Fisher syndrome/Pharyngeal-Cervical-Brachial variant-Guillain Barre Syndrome with anti-ganglioside complex antibodies

  • Lee, Suk-yoon;Oh, Seong-il;Huh, So-Young;Shin, Kyong Jin;Kim, Jong Kuk;Yoon, Byeol-A
    • Annals of Clinical Neurophysiology
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    • v.22 no.2
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    • pp.112-116
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    • 2020
  • Guillain-Barré syndrome (GBS) and Miller Fisher syndrome (MFS) can present with overlapping features. A 56-year-old female developed ptosis and diplopia after an upper respiratory infection, and presented with facial palsy, dysarthria, brachial weakness, ataxia, and areflexia. Mild weakness of both legs appeared after a few days. Anti-ganglioside complex antibody were positive to IgG GM1/GQ1b and GQ1b/sulfatide antibodies. The present case suggests that the manifestation of overlap between MFS/PCB variants and GBS could be caused by antiganglioside complex antibodies.

Differential Expression Patterns of Gangliosides in the Liver and Heart of NIH-miniature Pigs (NIH-미니돼지의 간과 심장에서 갱글리오시드의 서로 다른 발현 패턴)

  • Ryu, Jae-Sung;Chang, Kyu-Tae;Kim, Ji-Su;Kwak, Dong-Hoon;Lee, Young-Choon;Oh, Keon-Bong;Choo, Young-Kug
    • Journal of Life Science
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    • v.20 no.4
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    • pp.467-473
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    • 2010
  • Gangliosides are a major component of the plasma membrane of mammalian cells, which are directly involved in a variety of immunological events, including cell-to cell or cell-to-protein interactions. In this study, we investigated whether gangliosides, sialic acid-containing glycosphingolipids, are related to rejection during the xenotransplantation of NIH-miniature pig livers and hearts to humans. Both high performance thin-layer chromatography and immunohistochemistry analyses revealed that the expression of gangliosides in the liver tissue of NIH-miniature pigs was higher than that in the heart. Gangliosides GD3, GD1a, GD1b, GT1b and GQ1b were observed in both the liver and heart, whereas GQ1b was detected only in the liver, indicating that the ganglioside expression profiles are tissue specific. Moreover, other ganglio-series gangliosides, including GM3, were not detected in the livers and hearts of NIH-miniature pigs. Taken together, these results suggest that gangliosides may play important roles in immune responses in clinical xenotransplants of pig livers and hearts.

A case of Bickerstaff's brainstem encephalitis in childhood (Bickerstaff 뇌간 뇌염 1례)

  • Kim, Ji-Youn;Kim, Young-Ok;Son, Young-Jun;Woo, Young-Jong
    • Clinical and Experimental Pediatrics
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    • v.53 no.4
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    • pp.607-611
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    • 2010
  • Bickerstaff's brainstem encephalitis (BBE) is a rare disease diagnosed by specific clinical features such as 'progressive, relatively symmetric external ophthalmoplegia and ataxia by 4 weeks' and 'disturbance of consciousness or hyperreflexia' after the exclusion of other diseases involving the brain stem. Anti-ganglioside antibodies (GM, GD and GQ) in the serum or cerebrospinal fluid (CSF) are sometimes informative for the diagnosis of BBE because of the rarity of positive findings in other diagnositic methods: brain magnetic resonance imaging (MRI), routine CSF examination, motor nerve conduction study, and needle electromyography. We report a rare case of childhood BBE with elevated anti-GM1 antibodies in the serum, who had specific clinical symptoms such as a cranial polyneuropathy presenting as ophthalmoplegia, dysarthria, dysphagia, and facial weakness; progressive motor weakness; altered mental status; and ataxia. However, the brain MRI, routine CSF examination, nerve conduction studies, electromyography, somatosensory evoked potentials, and brainstem auditory evoked potentials were normal. BBE was suspected and the patient was successfully treated with intravenous immunoglobulins.

Associations Between Resilience and Gratitude in Patients With Depression and/or Anxiety Disorders (우울 및 불안장애 환자에서 리질리언스와 감사 성향의 관련성)

  • Min, Jung-Ah;Lee, Won Hee;Jung, Young-Eun;Hong, Hyeonmi;Chae, Jeong-Ho
    • Anxiety and mood
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    • v.18 no.1
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    • pp.26-31
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    • 2022
  • Objective : The levels of resilience and gratitude were examined in psychiatric patients with depression and/or anxiety disorders and compared to those of the general population. In addition, we analyzed the associations of positive affect, negative affect, depressive and anxiety symptoms, and gratitude on resilience in this patient population. Methods : The participants included a general population sample (n=155) and psychiatric outpatients with depression and/or anxiety disorders (n=108). All participants completed self-report questionnaires, which included demographic variables, the Connor-Davidson Resilience Scale (CD-RISC), the Gratitude Questionnaire-Six-Item Form (GQ-6), the Positive Affect Negative Affect Scale (PANAS), and the Hospital Anxiety and Depression Scale (HADS). Results : The CD-RISC and GQ-6 scores of patients with depression and/or anxiety disorders were significantly lower than those of the general population. In the patient population, hierarchical regression analysis showed that gratitude was significantly associated with resilience while controlling for a range of demographic and clinical variables. Conclusion : Patients with depression and/or anxiety disorder generally had lower resilience and gratitude. Moreover, our findings showed that gratitude could influence the levels of resilience in patients with depression and/or anxiety disorders.

First Report of Impatiens Necrotic Spot Virus on Plantago asiatica Cultivated in Open Fields (노지재배 질경이(Plantago asiatica)에서 봉선화괴저반점바이러스병 발생 국내 첫 보고)

  • Chung, Bong Nam;An, Tae Jin;Cho, In-Sook;Yoon, Ju-Yeon
    • Research in Plant Disease
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    • v.27 no.1
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    • pp.1-7
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    • 2021
  • In August 2020, necrotic ringspots on leaves were observed on 20 from 143 Plantago asiatica plants in open fields in Eumseong, Chungcheongbuk-do. Eight symptomatic Plantago asiatica plants were subjected to investigation on viral infection by reverse transcription and polymerase chain reaction. Impatiens necrotic spot virus, tomato spotted wilt virus and cucumber mosaic virus were detected from the symptomatic plants. Two impatiens necrotic spot virus (INSV) isolates ('INSV-plantain kr1' and '-plantain kr5') were sequenced and analyzed by comparing L genomic segment, nucleoprotein (N) gene and non-structural protein S (NSs) gene sequences. The nucleotide sequence of 'INSV-plantain kr1' isolate (MW114834) was most closely related to that of a 'Phalaenopsis' isolate (GQ336991) from China in the L genomic segment. 'INSV-plantain kr1' and '-plantain kr5' isolates shared the highest identities with those from 'Pepe' isolate (LC384872) and 'J' isolate (AB109100) in the NSs gene, respectively, and with that from 'YSMi-SH' isolate (FN400773) in the N gene. Phylogenetic analysis based on L genomic segment grouped the INSV-plantain kr1 isolate together with isolates from Korea (LC384870), China (GU112505, GQ336991), and Italy (DQ425094). This is the first report on INSV in P. asiatica from Korea.

Lossy Source Compression of Non-Uniform Binary Source via Reinforced Belief Propagation over GQ-LDGM Codes

  • Zheng, Jianping;Bai, Baoming;Li, Ying
    • ETRI Journal
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    • v.32 no.6
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    • pp.972-975
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    • 2010
  • In this letter, we consider the lossy coding of a non-uniform binary source based on GF(q)-quantized low-density generator matrix (LDGM) codes with check degree $d_c$=2. By quantizing the GF(q) LDGM codeword, a non-uniform binary codeword can be obtained, which is suitable for direct quantization of the non-uniform binary source. Encoding is performed by reinforced belief propagation, a variant of belief propagation. Simulation results show that the performance of our method is quite close to the theoretic rate-distortion bounds. For example, when the GF(16)-LDGM code with a rate of 0.4 and block-length of 1,500 is used to compress the non-uniform binary source with probability of 1 being 0.23, the distortion is 0.091, which is very close to the optimal theoretical value of 0.074.

Guillain-Barré syndrome associated with hyper-IgE-emia

  • Choi, Jongsuk;Rho, Jeong Hwa;Kim, Byung-Jo
    • Annals of Clinical Neurophysiology
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    • v.19 no.2
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    • pp.148-150
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    • 2017
  • Peripheral neuropathy associated with hyper-IgE-emia have been rarely reported. Here we present a 72-year-old man with acute motor axonal neuropathy who had relatively poor prognosis. The serum was weakly positive for IgG GQ1b and GT1a, and serum IgE was significantly elevated. He was transferred to a rehabilitation center with Medical Research Council grade 3 lower extremity weakness on admission day 65. We would suggest that hyper-IgE-emia may increase the magnitude and rate of neural damage in this case.

Development of Low Pressure Carburizing and High Pressure Gas Quenching System (뺏치식 저압침탄 고압가스냉각 시스템 개발)

  • Jang, Byoung-Lok;Han, Hyoung-Ki;Kim, Won-Bae;Dong, Sang-Keun;Kim, Han-Suck;Cho, Han-Chang
    • 한국연소학회:학술대회논문집
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    • 2005.10a
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    • pp.78-84
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    • 2005
  • The development of eco-friendly low pressure carburizing system with high pressure gas quenching (LPC_GQ, 500kg/charge) led to new stage in the fundamental case-hardening treatments. This is due to its ability to provide tighter tolerances on the carburizing process with notable reductions in distortion of the carburized and hardened workpiece. This system is characteristics by high uniformity and reproducibility of heat treatment results, absence of an intergranular oxidation layer, carburizing of complex shapes, reduced cycle time, low operating costs, simplified production, eliminate post washing, and reduced grinding costs.

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Performance Analysis of Dual-Plane Nonblocking Switches under Burst Traffic (버스트 트래픽 환경에서의 이중 평면 패킷 스위치의 성능 분석)

  • 이현태;손장우
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 1999.05a
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    • pp.142-145
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    • 1999
  • In this paper, delay performances are evaluated and compared for three dual-plane switch architectures; dual input queue/dual switching plane (DQDP The terms of DQDP, DQDP-PS and DQDP-GQ were not used in [Turner88], [Lee96] and [Son97]. All these tern are designated in this letter for convenience.) switch, DQDP with plane selector (DQDP-PS) switch and DQDP based on output group queueing (DQDP-OGQ) switch. We show that under random traffic these switches give almost identical delay performances to that of the output queueing switch but under bursty traffic only the DQDP-PS and the DQDP-OGQ switches ran do.

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