• The Journal of Korean Academy of Sensory Integration
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• v.17 no.1
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• pp.9-18
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• 2019

Objective : This study investigated the effect of intensive weight shift training (IWST) on the ability to balance in a sitting posture of children with spastic cerebral palsy (SCP). Methods : One child with spastic diplegia participated in this study for a total of 8 weeks using the ABA experimental design. For the pre-intervention period (A1), general physical therapy (GPT) for children with SCP was performed. The intervention period (B1 and B2), GPT and IWST were conducted for children with SCP, and GPT was conducted again for the post-intervention period (A'1 and A'2). Trunk control capacity was measured using the Korean Trunk Control Measurement Scale (TCMS-K) and Biorescue (RM Ingenierie, France). Results : All TCMS-K variables increased from A1 to B2, and decreased from B2 to A'2. The total area with limit of stability (LOS) increased from A1 to B2, and decreased from B2 to A'2. The ratio of the left/right (Lt/Rt) and anterior/posterior (Ant/Post) LOS area was closer to 1, meaning symmetry, in B2 than in A1. The ratio of the Lt/Rt LOS area decreased further from 1 in A'2 than in B2. The ratio of the Ant/Post LOS area was closer to 1 in A'2 than in B2. Conclusion : IWST had a positive effect on the improvement of balance in the sitting posture of a child with SCP. The results suggest that IWST might help to improve the balance abilities of children with SCP for independent sitting, postural control, and activities of daily living.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.14 no.1
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• pp.67-76
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• 2011

도시화로 인해 도심지와 도시외곽간의 기온차가 더욱 심해지는 열섬현상은 폭염과 더불어 도시민의 쾌적한 삶을 저해하는 요소로 작용하여 이를 저감하기 위한 노력이 시행되고 있다. 도시 기온은 도시의 지형적 특성, 도시 수체의 규모와 위치 등에 의해 영향을 받고 있는 것으로 알려져 있어 도시외곽에 산림이 존재하는 도시에서는 이들 지역과 도심지와의 기온차이를 측정하여 바람길을 이용한 기후응용도시계획에 활용할 필요가 있다. 허나, 아직 국내에서는 이들 기온 차에 대한 특성을 조사한 연구가 많지 않다. 이를 위해 본 연구에서는 서울시 강남 지역을 대상으로 도심지 상업업무중심지구 두 곳(GNS, SLS)과 도시외곽 산기슭 마을 두 곳(YGD, GPT) 간의 기온 차를 2008년 4월 14일부터 2009년 4월 13일까지 1년간 관측한 자료를 대상으로 일 변동, 계절별 변동을 비교, 분석하였다. 분석결과 관측 기간 동안 YGD는 연평균기온이 GNS보다 $2.8^{\circ}C$ 낮았으며 열대야는 GNS, SLS가 16일인데 비해 GPT는 2일, YGD는 하루도 관측되지 않아 도시외곽의 산림이 도시기온 저감효과가 있음을 확인하였다.

• Journal of Nutrition and Health
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• v.17 no.3
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• pp.199-209
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• 1984

Pregnant rats were fed a pyridoxine deficient diet during the gestation and lactation. DEF I group received the deficient diet from delivery ; DEF II group, from the 15 th day of gestation. Body and brain weights, brain protein, DNA, RNA, plasma GOT and GPT, and catecholamines were measured. Effect of MAO inhibiting drug, pargyline, was determined. Brain protein, DNA, and RNA of offsprings of deficient groups were significantly lower than the control group, but RNA/ DNA, brain weight/DNA, and protein/DNA show that cell number were more affected than cell size by the pyridoxine deficiency during the 3rd week of gestation and lactation. Plasma GOT activities were more significantly different than plasma GPT between the control and deficient group. Brain norepinephrine of offsprings of deficient group were significantly lower than the control, but brain dopamine content was not significantly different from the control. At 2nd and 3rd week, norepinephrine was significantly depressed in deficient groups. Pargyline treatment affected a 1.2 fold increase in catecholamines in 3hr while the control had a 1.5 fold increase. Thus norepinephrine and dopamine synthesis was depressed in the deficient groups. Dopaminergic neurons may be less dependent on pyridoxine level than neurons from norepinephrine. Pyridoxine deficiency in maternal diet is not so critical to brain catecholamines of offspring except to the neonatal rats.

• Journal of Environmental Health Sciences
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• v.12 no.2
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• pp.17-26
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• 1986

Earlier studies have shown that the administration of Na-alginate, a water-soluble, non absorbable acidic polysaccharide, effectively reduces the absorption of radioactive strontium, cadmium and other bivalent metals. In this study the effects of Na-alginate on the Toxicity induced by Lead and Cadmium were examined in rats and the following results were obtained. 1. The elevations of the activities of serum GOT, GPT by Pb and Cd administration in the experimental animals. However, the administration of Na-alginate significantly inhibited the elevation of serum GOT, GPT. 2. Generally serum TBA values were significantly elevated in Pb and Cd group in comparison with the control group. However, the administration of Na-alginate inhibited the elevation of serum TBA values. 3. The activity of Alkaline phosphatase was also significantly elevated in Cd group in comparison with the control group. However, the administration of Na-alginate significantly inhibited the elevation of serum alkaline phsphatase. 4. Furthermore, the activity of $\delta$-aminolevulinic acid dehydratase in red blood cells was also significantly inhibited by Pb and this inhibition was stimulated by the administration of Na-alginate. 5. The concentrations of Pb in liver and Cd in kidney were markedly increased by Pb and Cd. However, the administration of Na-alginate significantly inhibited the elevation of them.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.2
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• pp.143-148
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• 2014

Arecoline is a major alkaloid of areca nuts which are widely chewed by southeast Asian and it manifests various toxic effects in different organs of human and animals. In this work, mature mice were treated by vitamins C plus E, arecoline, or both daily for four weeks. The results showed that arecoline significantly increased the levels of serum alkaline phosphatase (ALP), glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and significantly decreased the levels of reduced glutathione (GSH), glutathione-S-transferase (GST), superoxide dismutase (SOD) and catalase (CAT) in the liver tissues. Additionally, the body weight, testis weight, sperm counts, motility and normal sperms also were significantly decreased. The supplement of vitamins C and E can bring the activities of ALP and GPT to normal levels and partially restore the sperm counts compared to the arecoline-treated group but have no other positive effects. In conclusion, the vitamins C and E partially attenuated the arecoline-induced hepatotoxiciy but basically had on protective effects against the arecoline-induced testicular toxicity.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.47 no.6
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• pp.860-868
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• 2014

The study was performed to investigate changes in hematological responses and antioxidative enzyme activities (superoxide dismutase, SOD; catalase, CAT) of Japanese eel Anguilla japonica following exposure to 0 (control), 2.33, 4.60, 6,64 and 8.78 mM nitrite-N in fresh water for 48 h. Hematological parameters such as plasma nitrite, electrolytes, cortisol, glucose, glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), hemoglobin (Hb), methemoglobin (metHb) and NADH-methemoglobin reductase (NMR) were measured. Plasma nitrite, cortisol, metHb and NMR increased directly with increasing ambient nitrite concentration, while Hb content showed a progressive decline. Levels of plasma potassium, GOT and GPT of the eel exposed to 6.64 mM ambient nitrite were significantly higher than the control fish. The activity of SOD and CAT in plasma, gill and liver of the eel following exposure to nitrite were augmented by increasing ambient nitrite. Levels of plasma nitrite, metHb, NMR, cortisol, glucose and antioxidative enzyme activities of the eel exposed to 2.33 mM ambient nitrite were significantly higher than the control fish. This study suggested that the eel acutely exposed to elevated ambient nitrite causes nitrite-induced stress responses, changes in antioxidative enzyme activities and hematological parameters.

• Preventive Nutrition and Food Science
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• v.2 no.2
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• pp.138-143
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• 1997

Crude catechin extracts were prepared using ethyl acetate from Korean Puerariae Radix (PR) and their biological effects on the alcoholic liver damage were investigated in male Sprague-Dawley rats (6 weeks old). Ethanol (5g ethanol/kg body weight/day) administration was performed for 8 weeks and after ethanol consuming rats were treated with one or two% catechin extracts of diet for 8 weeks. At the end of experimental period, lipid hydroperoxides in liver were analyzed using a chemiluminescence-high performance liquid chromatography (CL-HPLC) method. Compared with control animals, ethanol consumed rats showed lighter body weights, lower ratios of liver/body weight, higher activities of GOT and GPT, and increased lipid hydroperoxide amount in liver. With one or two% catechin extracts treatment, GOT and GPT activities returned to normal ranges. Lipid hydroperoxide contents in liver of on or two% PR treated rats lowered to 20% or 25% respectively, compared with the levels of those ethanol consumed animals without catechin extracts treatment. Therefore, we concluded that on or two% PR crude catechins treatment could be effective for alcoholic liver damage caused by lipid peroxidation.

• Journal of Information Technology Services
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• v.20 no.3
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• pp.75-86
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• 2021

As artificial intelligence is actively studied, chatbot systems are being applied to various fields. In particular, many chatbot systems for psychological counseling have been studied that can comfort modern people. However, while most psychological counseling chatbots are studied as rule-base and deep learning-based chatbots, there are large limitations for each chatbot. To overcome the limitations of psychological counseling using such chatbots, we proposes a novel psychological counseling AI chatbot system. The proposed system consists of a GPT-2 model that generates output sentence for Korean input sentences and an Electra model that serves as sentiment analysis and anxiety cause classification, which can be provided with psychological tests and collective intelligence functions. At the same time as deep learning-based chatbots and conversations take place, sentiment analysis of input sentences simultaneously recognizes user's emotions and presents psychological tests and collective intelligence solutions to solve the limitations of psychological counseling that can only be done with chatbots. Since the role of sentiment analysis and anxiety cause classification, which are the links of each function, is important for the progression of the proposed system, we experiment the performance of those parts. We verify the novelty and accuracy of the proposed system. It also shows that the AI chatbot system can perform counseling excellently.

• Annual Conference on Human and Language Technology
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• 2020.10a
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• pp.317-320
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• 2020

연설문은 구어체와 문어체 두 가지 특성을 모두 갖고 있는 복합적인 데이터 형태이다. 발화자의 문장 표현, 배열, 그리고 결합에 따라 그 구조가 다르기 때문에, 화자 별 갖는 문체적 특성 또한 모두 다르다. 국정을 다루는 정치인들의 연설문은 국정 현황을 포함한 다양한 주요 문제점을 다룬다. 그러면 발화자의 문서 내 문체적 특성을 고려할 경우, 해당 문서가 어느 정치인의 연설문인지 파악 할 수 있는가? 본 연구에서는 대한민국 정책 브리핑 사이트로부터 한국어 기반 사전 학습된 언어 모델을 활용하여 연설문에 대한 미세조정을 진행함으로써 발화자 예측 분류 모델을 생성하고, 그 가능성을 입증하고자 한다. 본 연구는 5-cross validation으로 모델 성능을 평가하였고 KoBERT, KoGPT2 모델에서 각각 90.22%, 84.41% 정확도를 보였다.

• Annual Conference on Human and Language Technology
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• 2023.10a
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• pp.91-94
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• 2023

자연스러운 상호작용이 가능한 인공지능 에이전트를 개발하기 위해서는 언어적 표현뿐 아니라, 비언어적 표현 또한 고려되어야 한다. 본 논문에서는 한국어 발화문으로부터 비언어적 표현인 모션을 생성하는 연구를 소개한다. 유튜브 영상으로부터 데이터셋을 구축하고, Text to Motion의 기존 모델인 T2M-GPT와 이종 모달리티 데이터를 연계 학습한 VL-KE-T5의 언어 인코더를 활용하여 구현한 모델로 실험을 진행하였다. 실험 결과, 한국어 발화 텍스트에 대해 생성된 모션 표현은 FID 스코어 0.11의 성능으로 나타났으며, 한국어 발화 정보 기반 비언어 표현 정보 생성의 가능성을 보여주었다.