• Pediatric Infection and Vaccine
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• v.10 no.1
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• pp.71-80
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• 2003

Purpose : Four kinds of Haemophilus influenzae type b protein conjugate vaccines, PRPD, PRP-T, PRP-OMP and PRP-CRM197, have been developed, and PRP-T vaccines are currently produced by two manufacturer, $ActHib^{(R)}$ by Aventis and $Hiberix^{TM}$ by GlaxoSmith-Kline Biologicals. The purpose of this study is to evaluate the immunogenicity and safety of $Hiberix^{TM}$ in Korean infants. Methods : Seventy-three healthy infants(43 male infants) were recruited for this study after parental informed consent was obtained. Each infant was vaccinated at 2, 4 and 6 months of age with the study vaccine. At each visit, infants were also immunized with DTaP, trivalent oral polio vaccine and hepatitis B vaccine when indicated. The serum anti-PRP antibody was measured at prevaccination, 2 month later after the 2nd dose, and 1 month later after the 3rd dose by the ELISA method. The local and systemic adverse reactions of vaccination were monitored for 3 consecutive days after each immunization. Immunogenicity of vaccine was evaluated in infants who received all the scheduled immunization and the adverse reactions were evaluated for infants who received at least one dose of the study vaccine. Results : Among seventy three infants, enrolled in this study; sixty three(37 male infants) completed all the scheduled immunizations. The geometric mean titer(GMT) of anti-PRP antibodies at prevaccination was 0.17 ${\mu}g/mL$(95% confidence interval[CI]; 0.13~0.22). The GMT of anti-PRP antibodies increased to 4.14 ${\mu}g/mL$(95% CI; 2.65~6.48) at 2 month later after the 2nd dose of PRP-T and 14.65 ${\mu}g/mL$(95% CI; 10.83~19.81) at 1 month later after the 3rd dose. Anti-PRP antibody ${\geq}0.15$ ${\mu}g/mL$, was observed in 98.4%(95% CI; 91.8~100) after 2 doses and 100%(95% CI; 100~100) after 3 doses. Anti-PRP antibody ${\geq}1.0$ ${\mu}g/mL$, was obtained in 77.8%(95% CI; 67.5~88.0) after 2 doses, and 98.4%(95% CI; 95.3~100) after 3 doses. Most of the adverse reaction after vaccination were mild. Irritability, the most common systemic reaction, was observed in 45.5%, followed by drowsiness(30.5%), poor feeding(26.7%) and fever(5.6%). Among the local reactions tenderness was observed in 7.9%, redness(${\geq}5$ mm) in 2.8% and swelling(${\geq}5$ mm) in 1.8%. Conclusion : The PRP-T vaccine used in this study was highly immunogenic and safe in Korean young infants. The finding that high GMT and high frequency of infants with a protective titer achieved after 2 doses is consistent with the previous studies which were done with a PRP-T vaccine of other manufacturer. This study suggests that the immunization schedule of PRP-T vaccine for Korean infants may need re-evaluation.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.47.1-47.1
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• 2015

We present an optical spectroscopic study of 28 supernova remnant (SNR) candidates in M81 and two SNR candidates in M82. The optical spectra of these SNR candidates were obtained using the MMT/Hectospec as a part of the K-GMT Science Program. Based on the [S II]/$H{\alpha}$ ratio and the radial velocity, we find that twenty six out of the M81 candidates are genuine SNRs. Two SNR candidates in M82 are thought to be shocked condensations in the galactic outflow or SNRs. In the spectral line ratio diagrams, M81 SNRs are divided into two groups: an [O III]-strong group and an [O III]-weak group. The [O III]-weak SNRs have larger sizes, and may have faster shock velocity. We estimate the nitrogen and oxygen abundance of the SNRs from the comparison with shock-ionization models. We find a radial gradient in nitrogen abundance, $dLog(N/H)/dlogR=-0.023{\pm}0.009\;dex\;kpc^{-1}$ little evidence for the gradient in oxygen abundance. The nitrogen abundance shows shallower gradient than those of the planetary nebulae and H II regions of M81. We find five X-ray emitting SNRs. Their X-ray hardness colors are consistent with thermal SNRs.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.53.1-53.1
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• 2015

The GMT-Consortium Large Earth Finder(G-CLEF) is one of the first light instruments at the Giant Magellan Telescope. The international consortium consists of five astronomical institutes including the Center for Astrophysics, the Observatories of Carnegie Institute, the University of Catolica in Chile, the University of Chicago, and Korea Astronomy and Space Science Institute, led by CfA. The extremely precise radial velocity capability is one of the principal instrumental feature of G-CLEF. The RV goal is 10 cm/s capable of detecting an Earth-like planet around a Sun-like host star. This high precision wavelength calibration stability requires a set of significantly tight optomechanical tolerances in the mechanical design of the Flexure Control Camera system. KASI is in charge of the Flexure Control Camera and the Calibration Light System for the G-CLEF spectrograph. In this presentation, we introduce the preliminary design and analysis results of the G-CLEF Flexure Control Camera.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.1
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• pp.56-63
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• 2014

An offshore plant needs costly maintenance and has difficulty coping with various accidents coming from the exposure to the environmental threats such as typhoons, tidal waves and etc., in addition to the artificial ones such as fire, collision of ships and etc. In this paper, we develop the video-complex remote monitoring system for an offshore plant, using AtoN AIS and multi-stage database to monitor an offshore plant and solve those problems. The system handles real time video cameras to collect and monitor images on an offshore plant. So, users can be exactly and quickly aware of the information on various situations with the monitoring application based on ENC.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.85.1-85.1
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• 2013

GMT(Giant Magellan Telescope)는 25.4m의 주경과 3.2m의 부경으로 이루어진 거대망원경이다. 3.2m의 부경은 빠른 tip-tilt로 망원경을 제어하는 Fast Steering Mirror(FSM)와 적응광학계로 이루어진 Adaptive Secondary Mirror (ASM)로 구분된다. 한국천문연구원은 국내외 협력기관들과 함께 부경 FSM의 시험모델개발을 수행하고 있다. 부경은 1.06m의 반사경 일곱 개로 이루어져 있는데, 한 개의 광축 반사경 주위로 여섯개의 비축 반사경이 둘러싸여서 하나의 3.2m 반사경과 같은 기능을 하고 있다. 비축 비구면 반사경에 대한 시험모델의 반사면을 가공한 결과 표면가공 정밀도가 11.7nm rms의 정밀도를 갖는 반사경을 가공하였다(target : <20nm rms). 또한 test-bed를 제작하여 tip-tilt 정밀도를 제어한 결과 성능요구 조건 값인 0.03arcsec 제어에 성공하였고, 더 나아가 0.01arcsec의 tip-tilt 제어도 가능한 것으로 판단된다.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.9
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• pp.1112-1118
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• 2014

In this paper, we propose a local descriptor and a similarity measure that is robust to radiometic variations. The proposed local descriptor is made up Haar wavelet filter and it can contain frequency informations about the feature point and its surrounding pixels in fixed region, and it is able to describe feature point clearly under ununiform illumination condition. And a proposed similarity measure is combined with conventional entropy-based similarity and another similarities that is generated by local descriptor. It can reflect similarities between image regions accurately under radiometic illumination variations. We validate with experimental results on some images and we confirm that the proposed algorithm is more superior than conventional algorithms.

• Journal of Digital Contents Society
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• v.16 no.6
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• pp.927-934
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• 2015

IMO e-Navigation is ongoing project for safety navigation and protection of maritime environment. Maritime Cloud is a part of e-Navigation Strategy Implementation Plan. It is IT framework technology for exchanging information among maritime stakeholders. We found configuration and operation process by analysis on Maritime Cloud architecture and EPD which is a client program. Through the result, we actually implemented client program. Client program targets Berthing data serviced on AIS-ASM. And we used MMS which is function of message exchanging of Maritime Cloud. The test result show data exchanging succeeded. And it will be helpful to develop Maritime Cloud service, to advance Korean Maritime Cloud.

• Journal of Digital Contents Society
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• v.16 no.6
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• pp.893-900
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• 2015

IMO has been proceeding in the maritime SQA for software quality is considered to be essential for the development of the introduction of the e-Navigation In order to ensure software quality, follow the prescribed procedures throughout the software development project and create the output as a result of executing the respective steps. This paper is introduced a case for applying to maritime software development using the tool that is capable of real-time monitoring and automated documentation. Also, It is discussed the improvement of procedures for applying the expected effects and maritime SQA for the tool utilization. The Development of customized tools for maritime SQA that is reflected an improved procedure for tool is the future goals.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.856-859
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• 2013

Ships and marine structures(lighthouses and buoys for AtoN) have AIS(Automatic Identification System) for transmission messages which include navigational and environmental information. VTS Center and surrounding ships receive and apply the information to safety navigation. A main characteristic of AIS messages is open to general people, so many researches are in progress. In this paper, we design an information management system which considers marine vessel traffic and environmental information in korean littoral sea. The system gathers and processes the information, and stores the processed data to multi-stage database. Also the system visualizes the stored data to use analysis and statistics based on ENC.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2015.10a
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• pp.45-46
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• 2015

The guideline on software quality assurance and human-centered design for e-Navigation was approved as IMO circular June 2015. e-Navigation software systems are characterized by a high proportion of data quality and quality in use. The purpose of this paper is to improve the quality in use of the maritime software quality assurance for the safety route guiding service. In this study, we added the stage which the stockholders such as a project manager, software developers, and end-users use the prototype that was developed based on the scenarios before the stage of design and development. Through this, we could review the requirement about the quality in use for a limited time at the beginning of the project. also we could raise understanding the concept of this project and goal system.