• Journal of the Korean earth science society
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• v.45 no.3
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• pp.173-191
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• 2024

Typhoons are significant meteorological phenomena that cause interactions among the ocean, atmosphere, and land within Earth's system. In particular, wind speed, a key characteristic of typhoons, is influenced by various factors such as central pressure, trajectory, and sea surface temperature. Therefore, a comprehensive understanding based on actual observational data is essential. In the 2015 revised secondary school textbooks, typhoon wind speed is presented through text and illustrations; hence, exploratory activities that promote a deeper understanding of wind speed are necessary. In this study, we developed a data visualization program with a graphical user interface (GUI) to facilitate the understanding of typhoon wind speeds with simple operations during the teaching-learning process. The program utilizes red-green-blue (RGB) image data of Typhoons Mawar, Guchol, and Bolaven -which occurred in 2023- from the Korean geostationary satellite GEO-KOMPSAT-2A (GK-2A) as the input data. The program is designed to calculate typhoon wind speeds by inputting cloud movement coordinates around the typhoon and visualizes the wind speed distribution by inputting parameters such as central pressure, storm radius, and maximum wind speed. The GUI-based program developed in this study can be applied to typhoons observed by GK-2A without errors and enables scientific exploration based on actual observations beyond the limitations of textbooks. This allows students and teachers to collect, process, analyze, and visualize real observational data without needing a paid program or professional coding knowledge. This approach is expected to foster digital literacy, an essential competency for the future.

• Journal of the Korean earth science society
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• v.45 no.1
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• pp.48-71
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• 2024

Typhoons are representative oceanic and atmospheric phenomena that cause interactions within the Earth's system with diverse influences. In recent decades, the typhoons have tended to strengthen due to rapidly changing climate. The 2022 revised science curriculum emphasizes the importance of teaching-learning activities using advanced science and technology to cultivate digital literacy as a citizen of the future society. Therefore, it is necessary to solve the temporal and spatial limitations of textbook illustrations and to develop effective instructional materials using global-scale big data covered in the field of earth science. In this study, according to the procedure of the PDIE (Preparation, Development, Implementation, Evaluation) model, the inquiry activity data was developed to visualize the track of the typhoon using the image data of GK-2A. In the preparatory stage, the 2015 and 2022 revised curriculum and the contents of the inquiry activities of the current textbooks were analyzed. In the development stage, inquiry activities were organized into a series of processes that can collect, process, visualize, and analyze observational data, and a GUI (Graphic User Interface)-based visualization program that can derive results with a simple operation was created. In the implementation and evaluation stage, classes were conducted with students, and classes using code and GUI programs were conducted respectively to compare the characteristics of each activity and confirm its applicability in the school field. The class materials presented in this study enable exploratory activities using actual observation data without professional programming knowledge which is expected to contribute to students' understanding and digital literacy in the field of earth science.

• Biomolecules & Therapeutics
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• v.27 no.1
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• pp.34-40
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• 2019

Transglutaminase 2 (TGase 2) plays a key role in p53 regulation, depleting p53 tumor suppressor through autophagy in renal cell carcinoma. We found that microtubule-associated protein 1A/1B-light chain 3 (LC3), a hallmark of autophagy, were tightly associated with the level of TGase 2 in cancer cells. TGase 2 overexpression increased LC3 levels, and TGase 2 knockdown decreased LC3 levels in cancer cells. Transcript abundance of LC3 was inversely correlated with level of wild type p53. TGase 2 knockdown using siRNA, or TGase 2 inhibition using GK921 significantly reduced autophagy through reduction of LC3 transcription, which was followed by restoration of p53 levels in cancer cells. TGase 2 overexpression promoted the autophagy process by LC3 induction, which was correlated with p53 depletion in cancer cells. Rapamycin-resistant cancer cells also showed higher expression of LC3 compared to the rapamycin-sensitive cancer cells, which was tightly correlated with TGase 2 levels. TGase 2 knockdown or TGase 2 inhibition sensitized rapamycin-resistant cancer cells to drug treatment. In summary, TGase 2 induces drug resistance by potentiating autophagy through LC3 induction via p53 regulation in cancer.

• Journal of the Korean Society of Food Culture
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• v.22 no.1
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• pp.157-165
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• 2007

This study was designed to evaluate the effects of fructose(F) or sucrose(S) and guar gum intake on carbohydrate and lipid metabolism in 15-week-old male Goto-Kakizaki(GK) rats. Fifty rats were randomly assigned to 5 groups which were different in carbohydrate(25% of carbohydrate) and fiber(5% w/w) sources. The carbohydrate(CHO) sources of each group were comstarch(control group, 100% of CHO), fructose with cellulose(F), fructose with guar gum(FG), sucrose with cellulose(S), and sucrose with guar gum(SG). Each group was fed exterimental diet for 4 weeks. We measured food intake, body weight gain, adipose tissues weight and organs weight. We conducted oral glucose tolerance test(OGTT) and measured plasma insulin concentration to examine carbohydrate metabolism. To evaluate lipid metabolism, we measured the lipid profile of plasma, liver and feces. Food intake and weight gain of FG or SG groups tended to be less than those of F or S groups. Perirenal and epididymal fat pad weights of SG group were significantly lower than those of S group and those of FG group tended to be lower than those of F group. In OGTT, blood glucose values of F or S groups were significantly higher than those of C group, and FG or SG groups tended to be lower than those of F or S groups during the experimental time. The area under the curve(AUC) of C group was significantly highest among the groups, AUC and plasma insulin concentration of FG or SG groups tended to be lower than those of F or S groups. Plasma and hepatic triglyceride (TG) of FG and SG groups were significantly lower than those of F and S groups, plasma and hepatic total lipid(TL) and total cholesterol(TC) of FG and SG groups tended to be lower than those of F and S groups. Fecal TL, TG and TC of FG or SG groups tended to be higher than those of F and S groups. In conclusion, intake of guar gum should improve carbohydrate and lipid metabolism in partial substitution of fructose or sucrose for cornstarch in GK rats.

• Korean Journal of Remote Sensing
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• v.38 no.6_1
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• pp.1181-1189
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• 2022

Clouds are composed of tiny water droplets, ice crystals, or mixtures suspended in the atmosphere and cover about two-thirds of the Earth's surface. Cloud detection in satellite images is a very difficult task to separate clouds and non-cloud areas because of similar reflectance characteristics to some other ground objects or the ground surface. In contrast to thick clouds, which have distinct characteristics, thin transparent clouds have weak contrast between clouds and background in satellite images and appear mixed with the ground surface. In order to overcome the limitations of transparent clouds in cloud detection, this study conducted cloud detection focusing on transparent clouds using machine learning techniques (Random Forest [RF], Convolutional Neural Networks [CNN]). As reference data, Cloud Mask and Cirrus Mask were used in MOD35 data provided by MOderate Resolution Imaging Spectroradiometer (MODIS), and the pixel ratio of training data was configured to be about 1:1:1 for clouds, transparent clouds, and clear sky for model training considering transparent cloud pixels. As a result of the qualitative comparison of the study, bothRF and CNN successfully detected various types of clouds, including transparent clouds, and in the case of RF+CNN, which mixed the results of the RF model and the CNN model, the cloud detection was well performed, and was confirmed that the limitations of the model were improved. As a quantitative result of the study, the overall accuracy (OA) value of RF was 92%, CNN showed 94.11%, and RF+CNN showed 94.29% accuracy.

• Korean Journal of Remote Sensing
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• v.36 no.3
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• pp.425-439
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• 2020

Through the operations of advanced geostationary meteorological satellite such as Himawari-8 and GK2A, higher resolution and frequency of AOD (Aerosol Optical Depth) data have become available. In this study, we analyzed the characteristics of Himawari-8/AHI (Advanced Himawari Imager) aerosol properties using the recent 4 years (2016~2019) of Sun photometer data observed at the five stations(Seoul National University, Yonsei University, Hankuk University of Foreign Studies, Gwangju Institute of Science and Technology, Anmyon island) which is a part of the AERONET (Aerosol Robotic Network). In addition, we analyzed the causes for the AOD differences between Himawari AOD and Sun photometer AOD. The results showed that the two AOD data are very similar regardless of geographic location, in particular, for the clear condition (cloud amount < 3). However, the quality of Himawari AOD data is heavily degraded compared to that of the clear condition, in terms of bias (0.05 : 0.21), correlation (0.74 : 0.64) and RMSE (Root Mean Square Error; 0.21 : 0.51), when cloud amount is increased. In general, the large differences between two AOD data are mainly related to the cloud amount and relative humidity. The Himawari strongly overestimates the AOD at all five stations when cloud amount and relative humidity are large. However, the wind speed, precipitable water, height of cloud base and Angstrom Exponent have been shown to have no effect on the AOD differences irrespective of geographic location and cloud amount. The results suggest that caution is required when using Himawari AOD data in cloudy conditions.

• Journal of the Korean GEO-environmental Society
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• v.15 no.2
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• pp.75-82
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• 2014

Recently, public works becoming bigger in Jeju are implemented various kinds of ground reinforcement method including the chemical grouting method. In this study, we have been investigated on the proper material and the injection condition for the excellent injection effect and the excellent strength of injection material and the permanent waterproof and reinforcement through the experiment. The kind of injection material has been selected through the uniaxial compression test and the endurance test of injection material as the chamber test. An experiment was performed with model ground made of scoria, the injection performance of selected material has been identified through the evaluation test of injection range using the decision test of injection amount and the calibration chamber test. As a result of test, it has been analyzed that MSG appeared to have the excellent strength, durability and injection performance all compared with the ordinary cement, this result is judged to be possible as the ancillary data of design at time of design and construction with the chemical grouting method in the future.

• Journal of Integrative Natural Science
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• v.15 no.4
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• pp.137-144
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• 2022

This paper presents the effect of the supramolecular complex of GA (Glycyrrhizic acid) and Mt(menthol) and GA: Mt (4: 1) obtained on their basis can restore functional dysfunction of the liver mitochondria in alloxan diabetes, ie, inhibit lipid peroxidation. The hypoglycemic activity and mitochondrial membrane stabilizing properties of the supramolecular compound GA: Mt (4: 1) in alloxan diabetes were more pronounced than those of menthol, GA and its GK: Mt (2: 1) and GA: Mt (9: 1) compounds. According to the results obtained, the concentration of GA did not affect the peroxidation of lipid membranes of the liver mitochondria. However, a concentration of 15 μM of GA was found to reduce LPO (lipid peroxidation) formed by the effect of Fe²+ / ascorbate on the mitochondrial membrane by 58.0 ± 5.0% relative to control. The inhibitory effect of GA and its supramolecular compounds in different proportions with menthol on the peroxidation of lipids in rat heart and brain tissue has been studied

• Korean Journal of Human Ecology
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• v.19 no.2
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• pp.399-407
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• 2010

The purpose of this study was to investigate the visual images of shirts according to coloration and the interval of checked patterns. The experimental stimulus and questionnaires for scaling response were developed for this study. The stimuli were 12 color pictures, in which the gender, coloration(WG: white+gray, WK: white+black, GK: gray+black), and interval(0.5 cm, 1.5 cm, 3.5 cm, 5.5 cm) were manipulated. The 7-point rating scale was used for evaluation of the visual image. Data were obtained from 144 male college students and 144 female college students living in Gyeonggi, Gyeongnam, Seoul, Gwangju, Daegu, and Busan on December 2009. For data analysis, ANOVA and the Duncan-test were used by using the SPSS program. The results of this study were as follows; the visual images for shirts according to the coloration and interval of checked patterns consisted of four dimensions of attractiveness, appeal, youth, and modesty. Gender was the main factor when looking at attractiveness. Coloration had the main effect on appeal, youth, and modesty. Also, there was a significant interaction effect of gender and coloration on attractiveness, while there was a significant interaction effect of coloration and interval on modesty.

• Journal of the Korean Applied Science and Technology
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• v.30 no.2
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• pp.332-338
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• 2013

This study was carried to investigate the antidiabetic effect of ethanol extract of Smallanthus sonchifolius(S.S) in Streptozotocin(STZ)- induced diabetic rats. Diabetes was induced by intravenous injection of STZ at a dose of 43mg/kg dissolved in citrate buffer. The ethanol extract of S,S in leaves and root were orally administrated once a day for 7 days at a dose of 1,000mg/kg. The contents of serum glucose, triglyceride(TG), total cholesterol were significantly decreased in S.S treated group compared to the those of STZ-control group. The content of hepatic glycogen and activity of glucokinase(GK) were significantly increased,and activity of glucose-6-phoshatase(G-6-Pase) was significantly decreased in S.S treated group compared to the those of STZ-control group, but activity of glucose-6-phosphate dehydrogenase(G-6-PDH) was not significantly increased, These results indicated that ethanol extract of S.S would have antidiabetic effect in STZ-induced diabetic rats.