• Bulletin of the Korean Space Science Society
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• 1993.04a
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• pp.16-16
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• 1993

The Cosmic Mach number M is the ratio of the bulk flow velocity of the galaxrvelocity field on some scale R to the unall scale velocity dispersion within refcions of scale R. Because M is the ratio of two velocities, it is inn-dimansionat and the Here, independent of the amplitude of the power specHim and of the biasplnmeter in the linear theory. We have measured the Mach rnlmber for two observational samples: a spiral galaxy sample(AHM) of Aaronson and hiscoBlaborators with absolute distances measured by the infrared Ttillr-Fisher relatioa and an elliptical galaxy sample(EGALS) of Faber or 0, with distances determined by the relation. The effective depths distances of galaxies from the Local Group of these samples are 1639 km/s and 2862 e/s, respectivelr. The Machnumbers from these observed peculiar velocity Selds He fund as M=0.95 for AHMand M=0.59 for EGALS. We comPBre these calculated Mach numbers with thosefrom meck surweys drawn fuom three cosnulogical medels: the stand8rd biased nh=0.5 CDM modet an open CDM rrudel with gh=0.2, and a medd with thepower-law power specelm P(k)-k-1 and n=1. The Mach rnlmber test can give robust constraints on these cosmelogical nudels whose power spectra have very different shapes at large scales.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.3
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• pp.815-818
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• 2003

Various kinds of chinese herbs have been known as to promote growth rate of animals. We investigated the growth promoting effect of the selected plants by using fish and rats as experimental animals. In a preliminary test by using fish, Eleutherococcus senticosus and Artemisia capillasis were found to be effective. Based on this result, we manufactured the mixture of plant extracts and applied this mixture to rice, named as Kiwoomi/sup TM/. When we administered Kiwoomi/sup TM/ to rats, it was found to be effective in growth promotion. Kiwoomi/sup TM/ - administered group showed 49.3% (0.75g/kg B.W.) and 52.3% (1.59/kg.B.W.) growth promotion, respectively. On the other hand, Control group showed 46.2% growth promotion. This growth promotion was supported by increase of GH and IGF-1 level in the Kiwoomi/sup TM/- administered group. From these results, we suggest that this functional rice could be helpful for growing children.

• Journal of the Korean Institute of Gas
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• v.17 no.5
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• pp.42-50
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• 2013

With the rapid change of industry and the development of science and technology, more than 100,000 industrial chemicals are being used and 2,000 new materials are developed every year. Chemical products have had favorable influence on our daily life and contributed very much to the prosper of human culture. But some materials are inherently poisonous and dangerous. Korea ranks as the number 7 in world's chemical products market and the chemical sector is contributing to the economic revival through importing and exporting of the products. With the increasing domestic as well as international interests about REACH and GHS, the need for the effective and efficient chemical material management system is getting bigger and bigger. In this research, we compare the criteria in UN GHS and Safety Control of Dangerous Substances Act of Korea for the development of global standard test methods and the classification and labelling for the chemicals, and suggest an advancement plan for the introduction of the GHS in a building block approach. In addition, providing the harmonized information about chemical hazards is suggested for the elimination of international trade barriers for chemical industries.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.3
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• pp.624-629
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• 2008

Effects of Kyungohkgo Ga Nokyong(Yongohkgo) on growth development and learning ability were investigated growth and intellectual impairment rat with insufficient nutrition diet. We divided male Sprague-Dawley rats into 4 groups. They were Normal group, Growth deficiency rat with insufficient nutrition diet group, Growth deficiency rat with 0.1% Yongohkgo group and 0.2% Yongohkgo group. They were administered for 5 weeks. We measured body weight, and morris water maze test in escape distance, escape time and escape speed, serum growth hormone, insulin-like growth factor and thyroid stimulating hormone, RBC, concentration of Hb and PCV ratio, total WBC and its composition, the values of GOT and GPT activities. The results are as follows that Yongohkgo 0.1%, 0.2% groups were showed significantly different than control groups in body weight and the counts of RBC. In the morris water maze test, in escape distance and escape time, in concentration of Hb and PCV ratio, 0.2% Yongohkgo group were significantly different than control groups. Serum growth hormone, insulin- like growth factor and thyroid stimulating hormone showed a tendency to increase in Yongohkgo groups. The counts of total WBC and its composition, GOT, GPT activities showed no significantly different in all treatment groups. These results suggested that Yongohkgo have an effect of promoting growth and learning ability of rats and might be effect to treat various kinds of growth and learning ability delay in children.

• Korean Journal of Biological Psychiatry
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• v.2 no.1
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• pp.3-19
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• 1995

Numerous investigators have conducted extensive investigation in the search for biological markers in psychiatric illness. There are, as a test of q biological approach to the diagnosis of the psychiatric illness, tests for the neurotransmitters, their metabolites, and related enzymes, the neurotransmitter receptors, the neuroendocrine output and response, the membrane transport, peptides and eletrolytes. They are called the biological markers, and they are helpful for the diagnosis or differential diagnosis, choice of treatment or drugs, symptom improvement, predictor of recurrence and anticipation of suicidal attempt. These studies are among the main purposes that are pursued in the neuroscience and based on the potential utility of the biological markers mentioned above. Since 1970's, lots 01 biological markers' studies for the diagnosis, differential diagnosis or subtypes differentiation have been done but varieties of different opinions have been drawn since then through they could explain the charaters of main psychiatric illness(especially schizophrenia and mood disorder). But, the search for biological markers, including displines of neuroendoclinology and neurochemistry(neurotransmitter and thair metabolite), has yielded a number of putative trait merkers and state markers for psychayric illness. This paper aims to anticipate or evaluate the good response to the therapy(Therpeutic response) with lots of markers. Acoording to the diagnosis of lots of diseases or subtypes, we are going to review the papers, mainly concern with 'Is there any Marker' or 'Is any test possible to detect the improvement clinically?' 'Is it possible to predict the recurrence or good prognsis?' or 'Is it possible to select any drug or therapy to bring the good response?' The biological tests to review are mainly the metabolites of catecholamine neurotransmitter, and especially neuroendocrine test based on the knowledge that hormons of the adenohypophysis are influenced by activity of the cerebral or limbic neurons as well as the hypothalamus ones. Among them, author introduced some clinically available tests that are DST, TRH stimulation test(TRHST), GH stimulation test, and the urine MHPG test that can give us the evaluation of the treatment response, the predictor for recurrence or choice of drug that can bring a good response. So author discussed thair potential utility in clarifying, therapeutic, and prognostic issues in psychatric illness. We hope they'll be used and look forward to more active study on the different opinion.

• Journal of Life Science
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• v.25 no.6
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• pp.680-685
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• 2015

Previously, cellulase and xylanase producing microorganism, Bacillus subtilis NC1, was isolated from soil. Based on the 16S rRNA gene sequence and API 50 CHL test the strain was identified as Bacillus subtilis, and named as B. subtilis NC1. We cloned and sequenced the genes for cellulase and xylanase. Plus, the deduced amino acid sequences from the genes of cellulase and xylanase were determined and were also identified as glycosyl hydrolases family (GH) 5 and 30, respectively. In this study to optimize the medium parameters for cellulase production by B. subtilis NC1 the RSM (response surface methodology) based on CCD (central composite design) model was performed. Three factors, tryptone, yeast extract, and NaCl, for N or C source were investigated. The cellulase activity was measured with a carboxylmethyl cellulose (CMC) plate and the 3,5-dinitrosalicylic acid (DNS) methods. The coefficient of determination (R²) for the model was 0.960, and the probability value (p=0.0001) of the regression model was highly significant. Based on the RSM, the optimum conditions for cellulase production by B. subtilis NC1 were predicted to be tryptone of 2.5%, yeast extract of 0.5%, and NaCl of 1.0%. Through the model verification, cellulase activity of Bacillus subtilis NC1 increased from 0.5 to 0.62 U/ml (24%) compared to the original medium.

• Journal of the Korean Electrochemical Society
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• v.11 no.2
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• pp.115-119
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• 2008

Single particle of nickel hydroxide and the surface-treated one with cobalt element were performed to review the effect of LiOH additive in alkaline electrolyte for Ni-MH batteries using microelectrode test system. As a result of cyclic voltammetry, the electrochemical behaviors such as the oxidation/reduction and oxygen evolution reaction are clearly observed for a single particle of nickel hydroxide, respectively. Furthermore, the reduction current peak of nickel hydroxide added with LiOH in electrolyte was very low and broad compared with the normal nickel hydroxide without an additive LiOH, which had a bad effect to the crystallization structure of nickel hydroxide. However, it was found that capacity and cycle properties of the nickel hydroxide treated with cobalt greatly increased by the addition of LiOH.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2815-2819
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• 2014

Background: The aim of this study was to evaluate the prognosis of patients with stage IA-IIB cervical carcinoma and to investigate a possible correlation of histology with prognosis. Materials and Methods: Two hundred fifty one patients with adenocarcinoma and squamous cell carcinoma (SCC) histology for FIGO (International Federation of Gynecology and Obstetrics) stage IA-IIB uterine cervical carcinomas at the Radiation Oncology Clinic of GH Okmeydan Training and Research Hospital between January 1996 and December 2006 were selected, analyzed retrospectively and evaluated in terms of general characteristics and survival. Disease-free survival (DFS) and overall survival (OS) was calculated using the Kaplan-Meier method and differences were compared with the log-rank test. Multivariate analysis using a Cox-proportional hazards model was used to adjust for prognostic factors and to estimate hazard ratio (HR) with 95% confidence interval (CI). Results: There was no differences between the two tumour types in age, stage, pelvic nodal metastasis, parametrial invasion, surgical margin status, DSI, LVSI, maximal tumor diameter, grade, and treatment modalities. 5-year OS and DFS were 73% and 77%, versus 64% and 69%, for SCC and adenocarcinoma, respectively (p> 0.05). Multivariate analysis revealed independent prognostic factors including pelvic nodal metastasis and resection margin status for OS (p=0.008, p=0.002, respectively). Conclusions: Prognosis of FIGO stage IA-IIB cervical cancer patients was found to be the same for those with adenocarcinoma and SCC.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 1999.05a
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• pp.45-45
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• 1999

일반 구조용 탄소강은 수용액 중에 노출될 때 부식에 의한 손상을 받기 쉽다. 부식의 양지를 위한 방법으로 사용 매체 중에 부식억제제를 첨가하여 탄소강의 부식속도를 낮추는 방법은 흔히 사용되는 방법이다. 부식억제제는 부식억제의 원리에 따라 양극부식억제제, 음극부식억제제 그리 고 이들의 혼합부삭억 세제 둥 여러 종류가 목적에 따라 사용되고 있다. 일반적으로 부식억제제의 성능 평가에는 무게감량볍, 표면분석법, 분극거동측정, 부석전위, 선 형분극법에 의한 부식속도 측정 등 다양한 방법이 시도되고 있다. 이 중에서 전기화학적 평가볍 은 부삭억제제의 작용 기구 규명 등을 위하여 많이 사용되고 있다. 한편 제품의 개발 단계에서 실질적인 평가법으로 갈리 사용하고 있는 방법은 무게 감량법인데 이 방법은 전면부식에 의한 금 속 손실량을 측정하여 부식억제능을 측정하는 방법이다. 그러냐 실제로 부삭억제제가 사용되고 있는 환경에서의 부식양상을 판찰하여보면 전면부식에 의한 손상보다는 국부부식에 의한 손상이 보다 치명적언 경우를 종종 목격할 수 있다. 이러한 관점에서 가존의 무게감량법은 한계가 있다. 따라서 본 연구에서는 이러한 국부부식을 보다 효과적으로 평가하기 위해 새로운 시험법을 도 입 상용 부식억제제의 종류별로 비교하였다. 부식억제제로는 수용액 중의 부식억제제로 널리 사용되고 있는 Nalco 39L과 본 연구실에서 SK해미칼과 공동 개발한 GH-110 등에 대하여 MCA(Multiple Crevice Assembly)를 이용 틈부식 저항성을 평가하였다. 또한 박막화된 전기저항형 부석속도 측정 센서를 틈부식 형태의 부식측정 에 적용하는 연구를 행하였다. 시험에 사용한 재갚는 천연가스의 감압 온도보상용으로 운전하는 가스히터의 주 구성 재료인 저탄소강을 사용하였으며 열화된 부식억제제 용액으로 사용기간이 서로 다른 수용액들에 대하여 평가 방법을 적용하여 비교하였다 다양한 부식억 제 제 수용액을 비교한 결과 MCA(Multiple Crevice Assembly)를 이용한 틈부식 억제능 시험은 실제 현장 사험 결과와 어느 정도 일치하는 결과를 보였다. 새로운 틈부식 저항성 측정법으로 시도한 철박막을 이용 틈부식 측정법은 육안 검사를 실시하지 않고도 틈부식의 전행 여부를 확인할 수 있는 가능성을 확인하였다.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.4
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• pp.15-24
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• 2014

Objectives: There were only small studies about the difference of the quality of life depending on blood stasis. We investigated that the blood stasis made the differences of quality of life. Methods: We recruited the participants stratified according to age and gender. The participants were assessed independently by two Korean medicine doctors more than 7 years of clinical experiences whether or not with blood stasis. And they responded at the questionnaire associated with blood stasis and SF-36. The analysis was done with IBM SPSS Statistics (ver. 21). Results: Total 101 participants were checked for with/without blood stasis. 40 participants were accord in the diagnosis with blood stasis by two doctors. Two researchers coincided in diagnosis with non-blood stasis in 42 participants. 19 participants showed the discrepancy between the assessment of blood stasis and they were classified as non-blood stasis. The mean age in group of blood stasis was $44.07{\pm}11.65$, it was not shown the significant difference comparing non-blood stasis group. The subscale of physical function (PF), role-physical (RP), bodily pain (BP), general health (GH), vitality (VT), mental health (MH) and role emotional (RE) in SF-36 were significantly low in the group of blood stasis. Blood test including biochemistry, fibrinogen, prothrombin time and D-dimer was not in abnormal range according to blood stasis without CRP. Conclusions: The patients that diagnosed of blood stasis showed the bad physical health status, and partially bad mental health. It is necessary to investigate whether Korean traditional treatment for blood stasis would be made improvement for quality of life. Moreover, the standardization of diagnosis on blood stasis would be needed.