• Title/Summary/Keyword: GG Method

Search Result 155, Processing Time 0.026 seconds

Role of +405C>G and +936C>T Polymorphisms of the Vascular Endothelial Growth Factor Gene and Risk of Esophageal Cancer in the Kashmiri Population

  • Qasim, Iqbal;Bhat, Imtiyaz Ahmad;Masoodi, Khalid Zafar;Shah, Zafar Amin
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.1
    • /
    • pp.97-101
    • /
    • 2015
  • Background: The gene for the vascular endothelial growth factor (VEGF), which promotes angiogenesis and permeability, is polymorphic. The aim of the present study was to evaluate the relationship between +936C>T and +404C>G polymorphism of VEGF with risk of esophageal cancer in the Kashmiri population in India. Materials and Methods: 150 esophageal cancer patients and 150 unrelated healthy controls were genotyped for two VGEF SNPs (+405C/G, and +936C/T) using DNA extracted from prospectively collected blood samples by the PCR-RFLP method. Results: For the VEGF +936C>T polymorphism a significant association of CT and combined CT+TT genotypes was observed with increased risk of esophageal cancer (p=0.021; 0.024). For the +405C>G polymorphism we observed significantly increased frequency of GG genotype in cases as compared to controls and also the +405 GG Genotype was observed to have a two fold risk(OR=2.7356; 95%CI=1.1409-6.5593; p=0.020). The combined genotypes of GG-CC and GG-CT of +405C>G and +936C>T were found to be significantly associated with increased risk of esophageal cancer (p=0.0376; 0.0099). Conclusions: From the results of the present study a significant association of +936C>T and +405C>G polymorphisms with increased esophageal cancer risk exists in the Kashmiri population.

A Study on the Medical Records and Qian Yi(錢乙)'s Medical Thought in $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ (소아약증직결(小兒藥證直訣)의 의안(醫案)에 나타난 전을(錢乙)의 의학사상에 관한 연구)

  • Hwang, Young Jun;Min, Sang Yeon;Kim, Jang Hyun
    • The Journal of Pediatrics of Korean Medicine
    • /
    • v.24 no.1
    • /
    • pp.104-116
    • /
    • 2010
  • Objectives The Medical record consist of symptoms, the cause of a disease, diagnostic studies, medical treatment, prescription, and so on. Doctors can use medical records as data for diagnosis, treatment, and education. Therefore, medical records are beneficial. Methods Translating $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ into modern Korean, and studying the medical records of Qian Yi(錢乙)'s Medical concept in $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ were examined. Results Regarding the diagnosis of the pediatric diseases, Si Zhen He Can(四該合參), consider in the eye exam closely. In addition, he closely combined the concept of Wu Zang Bian Zheng(五藏辨證), and diagnosis the pediatric diseases. Wu Zang Bian Zheng(五藏辨證). what Qian-Yi(錢乙) established method was based on Zheng Ti Guan(整體觀) in Huang Di Nei Jing(黃帝內經). Qian-Yi(錢乙) took a close look on Chuang Zhen(瘡疹) which had been an inadequate field in those days. He criticized on the habitual misuse of medications. He treated Ji Jing(急驚) and Man Jing(慢驚) separately; Ji Jing(急驚) as Liang Xie(凉瀉) and Man Jing(慢驚) as Wen Bu(溫補). He proposed Zong Gan Zhu Feng and Xin Zhu Jing(縱肝主風, 心主驚) theory and formulated Jing Feng(驚風) theory as well. He emphasized the treatment to Gong Bu Shang Zheng, Bu Bu Zhi Xie, Xiao Bu Jian Shi(攻不傷正, 補不滯邪, 消補兼施) because he had a clear demonstration to Han Re Xu Shi(寒熱虛實) of the five viscera in the field of Fang yao(方藥). Conclusions Understanding $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ and its medical records of Qian Yi(錢乙)'s medical concept had quintessential meaning to both modern pediatrician and oriental medical doctors of all medical fields in treating children.

The Effect of A-3826G Polymorphism of Uncoupling Protein-Ion Visceral Fat Area in Overweight Korean Women

  • Kim, Kil-Soo;Cha, Min-Ho;Kim, Jong-Yeol;Shin, Seung-Uoo;Yoon, Yoo-Sik
    • Preventive Nutrition and Food Science
    • /
    • v.10 no.3
    • /
    • pp.279-284
    • /
    • 2005
  • Uncoupling protein-1 (UCP-1) plays a major role in thermogenesis, and has been implicated in the pathogenesis of obesity and metabolic disorders. The aim of this study was to estimate the effects of A-3826G polymorphism of UCP-1 gene on body fat distribution. Two hundred forty eight Korean female overweight subjects with BMI more than 25 kgfm2 participated in this study. The areas of abdominal subcutaneous and visceral fat of all subjects were measured from computed tomography cross sectional pictures of the umbilical region. Subcutaneous fat areas of upper and lower thigh were also measured. Body composition was measured by bio-impedance analysis, and serum concentrations of biochemical parameters, such as glucose, triglyceride, cholesterol etc, were also measured. Genotype of UCP-1 was analyzed by polymerase chain reaction (PCR) restriction fragment length polymorphism (RFLP) method. The frequencies of UCP-1 genotypes were AA type; $27.8\%,\;AG\;type;\;51.2\%\;and\;GG\;type;\;21.0\%,$ and the frequency of G allele was 0.47. Body weight, BMI, WHR, SBP, DBP and body compositions were not significantly different by UCP-1 genotype. Abdominal visceral fat area was significantly higher in AG and GG type compared with AA type (p=0.009), but subcutaneous fat areas were not significantly different by UCP-1 genotype. Among biochemical parameters, LDL cholesterol level was significantly higher in GG type compared with AA and AG types (p=0.033). Among all subjects, 121 subjects finished 1 month weight loss program containing hypocaloric diet and exercise. The reduction of body weight and BMI were lower in GG type compared with AA/AG type even though statistical significances were not found (p > 0.05). These results suggest that UCP-1 genotype has a significant effect on visceral fat accumulation among Korean female overweight subjects with BMI more than $25\;kg/m^2$.

Methane emission from municipal solid waste dumpsites: A case study of Chennai city in India

  • Srinivasan, Pavithrapriya;Andimuthu, Ramachandran;S.N., Ahamed Ibrahim;Ramachandran, Prasannavenkatesh;Rajkumar, Easwari;Kandasamy, Palanivelu
    • Advances in environmental research
    • /
    • v.9 no.2
    • /
    • pp.97-107
    • /
    • 2020
  • The indiscriminate growth in global population poses a threat to the world in handling and disposal of Municipal solid waste. Rapid urban growth increases the production, consumption and generation of Municipal solid waste which leads to a drastic change in the environment. The methane produced from the Municipal Solid waste accounts for up to 11% global anthropogenic emissions, which is a major cause for global warming. This study reports the methane emission estimation using IPCC default, TNO, LandGEM, EPER and close flux chamber from open dump yards at Perungudi and Kodungaiyur in Chennai, India. The result reveals that the methane emission using close flux chamber was in the range of 8.8 Gg/yr-11.3 Gg/yr and 6.1Gg/yr to 9.1 Gg/yr at Kodungaiyur and Perungudi dump yard respectively. The per capita waste generation was estimated based on waste generation and population. The waste generation potential was projected using linear regression model for the period 2017-2050. The trend of CH4 emission in the actual field measurement were increased every year, similarly the emission trend also increased in IPCC default method (mass balance approach), EPER Germany (zero order decay model) where as TNO and Land GEM (first order decay model) were decreased. The present study reveals that Kodungaiyur dump yard is more vulnerable to methane emission compared to Perungudi dump yard and has more potential in waste to energy conversion mechanisms than compare to Perungudi dump yard.

Influence Appraisal for Labor Statistics after Introducing a New Survey Method (노동부 통계자료에 대한 새로운 조사방법의 영향 평가)

  • 성내경
    • Survey Research
    • /
    • v.4 no.2
    • /
    • pp.47-62
    • /
    • 2003
  • Based upon the Labor Demand Survey and the Survey on Wage Structure being conducted annually by the Ministry of Labor, we suggest a convenient statistical tool which can analyze and appraise the effect of introducing a new survey method. Since both surveys have in common very similar sampling frames and sampling schemes in structure, one can measure the variability of one survey on the basis of the other. The influence appraisal method adopted here is applied to ratio data between two independent estimates belonging to the identical category by year and has a statistical form of comparing ratio data before introducing a new survey with those after introducing a new survey.

  • PDF

An Analysis on Processes of Justifying the Standard Fraction Division Algorithms in Korean Elementary Mathematics Textbooks (우리나라 초등학교 수학 교과서에서의 분수 나눗셈 알고리즘 정당화 과정 분석)

  • Park, Kyo Sik
    • Journal of Elementary Mathematics Education in Korea
    • /
    • v.18 no.1
    • /
    • pp.105-122
    • /
    • 2014
  • In this paper, fraction division algorithms in Korean elementary mathematics textbooks are analyzed as a part of the groundwork to improve teaching methods for fraction division algorithms. There are seemingly six fraction division algorithms in ${\ll}Math\;5-2{\gg}$, ${\ll}Math\;6-1{\gg}$ textbooks according to the 2006 curriculum. Four of them are standard algorithms which show the multiplication by the reciprocal of the divisors modally. Two non-standard algorithms are independent algorithms, and they have weakness in that the integration to the algorithms 8 is not easy. There is a need to reconsider the introduction of the algorithm 4 in that it is difficult to think algorithm 4 is more efficient than algorithm 3. Because (natural number)${\div}$(natural number)=(natural number)${\times}$(the reciprocal of a natural number) is dealt with in algorithm 2, it can be considered to change algorithm 7 to algorithm 2 alike. In textbooks, by converting fraction division expressions into fraction multiplication expressions through indirect methods, the principles of calculation which guarantee the algorithms are explained. Method of using the transitivity, method of using the models such as number bars or rectangles, method of using the equivalence are those. Direct conversion from fraction division expression to fraction multiplication expression by handling the expression is possible, too, but this is beyond the scope of the curriculum. In textbook, when dealing with (natural number)${\div}$(proper fraction) and converting natural numbers to improper fractions, converting natural numbers to proper fractions is used, but it has been never treated officially.

  • PDF

A study on the reason that pulse-feeling method of meridians diagnosis flows into diagnostic method by taking pulse of setting six region for Chon(寸), Gwan(關) and Cheok(尺), i.e. the Chon[寸] spot pulse -A study on the transition of pulse-feeling method- (경맥진단(經脈診斷)의 맥진법(脈診法)이 기구맥(氣口脈)의 촌관척(寸關尺) 육부정위맥진법(六部定位脈診法)으로 연변(演變)된 연유(緣由)에 관(關)한 연구(硏究) -경맥학설(經脈學說) 및 맥진법(脈診法)의 상관성(相關性)-)

  • Lim, Han-je;Yoon, Jong-hwa
    • Journal of Acupuncture Research
    • /
    • v.21 no.1
    • /
    • pp.1-20
    • /
    • 2004
  • Pulse-feeling took its origin from making a diagnosis along meridians in the course of discovering and forming meridians and for a long time its meaning was mixed with meridians in the course of recognizing "The Pulse" then was separated from meridians in the early days of Western Han Dynasty. Ancient pulse-feeling methods are pulse-feeling method by the twelve regular meridians, pulse-feeling method by three regions and nine modes, pulse-feeling method by Inyeong(人迎) and Chon-gu(寸口), etc. Pulse-feeling was changed in proportion to diagnostic purpose and method of treating and if method and region of pulse-feeling is arranged, we will infer correlation between meridians and pulse-feeling and will infer transitional system of past pulse-feeling and will forecast transition of future pulse-feeling. As the result that I study the transition of the above three pulse-feeling methods of meridians diagnosis: 1. Three pulse-feeling methods of meridians diagnosis flowed into diagnostic method by taking pulse of setting six region for Chon(寸), Gwan(關) and Cheok(尺), i.e. the Chon[寸] spot pulse of $\ll$Nan-gyeong$\gg$ and were changed into diagnostic method being fit for use of five Su points, The Front-Mo points and Back-Su points that grasp the pathology of mutual internal organs and treat the disease. 2. Today it is suggesting the transition of another pulse-feeling method that do not apply diagnostic method by taking pulse of setting six region for Chon(寸), Gwan(關) and Cheok(尺), i.e. the Chon[寸] spot pulse of $\ll$Nan-gyeong$\gg$ to 19C Sasang(四象) Constitutional Medicine or 20C Eight Constitutional Medicine.

  • PDF

Adaptive Digital Watermarking using Stochastic Image Modeling Based on Wavelet Transform Domain (웨이브릿 변환 영역에서 스토케스틱 영상 모델을 이용한 적응 디지털 워터마킹)

  • 김현천;권기룡;김종진
    • Journal of Korea Multimedia Society
    • /
    • v.6 no.3
    • /
    • pp.508-517
    • /
    • 2003
  • This paper presents perceptual model with a stochastic multiresolution characteristic that can be applied with watermark embedding in the biorthogonal wavelet domain. The perceptual model with adaptive watermarking algorithm embeds at the texture and edge region for more strongly embedded watermark by the SSQ. The watermark embedding is based on the computation of a NVF that has local image properties. This method uses non- stationary Gaussian and stationary Generalized Gaussian models because watermark has noise properties. The particularities of embedding in the stationary GG model use shape parameter and variance of each subband regions in multiresolution. To estimate the shape parameter, we use a moment matching method. Non-stationary Gaussian model uses the local mean and variance of each subband. The experiment results of simulation were found to be excellent invisibility and robustness. Experiments of such distortion are executed by Stirmark 3.1 benchmark test.

  • PDF

Discussion on the Clinical meanings of the Collateral Diagnosis Method in the "Hwangjenaegyeong(黃帝內經)" (약론(略论) $\ll$내경(内经)$\gg$ 낙맥진법적림상의의(络脉诊法的临床意义))

  • Wang, Xiao-Ping
    • Journal of Korean Medical classics
    • /
    • v.23 no.1
    • /
    • pp.317-319
    • /
    • 2010
  • The collateral diagnosis method is unique in Traditional Chinese Medicine diagnosis methods which has important clinical value. In my article, the contents of the "Hwangjenaegyeong(黃帝內經)" related to this method is discussed. According to the site of inspection in the diagnosis process, there are five types as following: inspection of the face and surface, the thenar, the orifices, abdominal collaterals and finally the index finger of children. This method can inspire clinical practitioners.

A Study on the Derivation of Bracket Structure Terminology in Yingzaofashi in the Era of Song Dynasty (송대(宋代) ${\ll}$영조법식(營造法式)${\gg}$ 대목작(大木作) 포작(鋪作) 관련용어의 파생에 관한 연구)

  • Kim, Jae-Ung
    • Journal of architectural history
    • /
    • v.20 no.2
    • /
    • pp.55-70
    • /
    • 2011
  • This paper aimed at analyzing of structural carpentry terminology for bracket structure in Yingzaofashi ${\ll}$營造法式${\gg}$in the era of Song Dynasty and illuminating coinage characteristics and method of Structural Carpentry Terminology for bracket Structure through graphonomy research and system and structure of these terms. The results are as follow. The structural carpentry terminologies for structure were identified to be approximately 23 words, and terminology of bracket structure鋪作 is largely categorized into 3 categories of Type鋪作次序, Structure, Place. On the other hand, the structural carpentry terminologies for parts largely categorized into 2 categories of Bracket structure鋪作, Others. Bracket structure terminologies for parts were derived from the core of Dou枓, Gong栱, Ang昂, Fang方. The phenomena of derivation in structural carpentry terminology for bracket structure can be explained by the difference in the shape of subsidiary material and the location for usage of the subsidiary material and part of the subsidiary material and their functions.