• Title/Summary/Keyword: GBR

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Biomimetic characteristics of mussel adhesive protein-loaded collagen membrane in guided bone regeneration of rabbit calvarial defects

  • Song, Woong-Kyu;Kang, Joo-Hyun;Cha, Jae-Kook;Lee, Jung-Seok;Paik, Jeong-Won;Jung, Ui-Won;Kim, Byung-Hoon;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.48 no.5
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    • pp.305-316
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    • 2018
  • Purpose: The aim of the present study was to evaluate the biocompatibility and barrier function of mussel adhesive protein (MAP)-loaded collagen membranes in guided bone regeneration (GBR). Methods: Eight male New Zealand white rabbits were used. Four circular defects (diameter: 8 mm) were created in the calvarium of each animal. The defects were randomly assigned to 1) a negative control group, 2) a cyanoacrylate (CA)-loaded collagen membrane group (the CA group), 3) a MAP-loaded collagen membrane group (the MAP group), and 4) a group that received a polycaprolactone block with MAP-loaded collagen membrane (the MAP-PCL group). Specimens were harvested at 2 weeks (n=4) and 8 weeks (n=4) postoperatively for observational histology and histometric analysis. Results: In the histologic analysis, MAP was completely absorbed without any byproducts. In contrast, some of the CA adhesive remained, showing an inflammatory reaction, at 8 weeks. In the MAP-PCL group, the MAP-loaded collagen membranes served as a barrier membrane despite their fast degradation in GBR. No significant difference was found in the amount of new bone between the MAP-PCL and MAP groups ($1.82{\pm}0.86mm^2$ and $2.60{\pm}0.65mm^2$, respectively). Conclusions: The MAP-loaded collagen membrane functioned efficiently in this rabbit calvarial GBR model, with excellent biocompatibility. Further research is needed to assess clinical applications in defect types that are more challenging for GBR than those used in the current model.

A BIOLOGIC STUDY ON TOOTHASH - PLASTER OF PARIS MIXTURE WITH ABSORBABLE COLLAGEN MEMBRANE IN THE TREATMENT OF PERI-IMPLANT DEFECTS (임플란트 주위염 치료시 치아회분말과 치과용 연석고의 혼합 매식의 골재생 효과)

  • Choi, Hee-Yeon;Kim, Hak-Kyun;Kim, Su-Gwan;Moon, Seong-Yong;Kim, Sang-Yeol;Park, Kwang-Bum;Kim, Young-Min;Lim, Seong-Chul;Kim, Eun-Seok;Lee, Jeong-Hoon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.2
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    • pp.142-149
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    • 2008
  • The purpose of this study was to evaluate histomorphometrically a toothash - plaster of Paris mixture associated with collagen membrane ($Bio-Gide^{(R)}$), regarding new bone formation in the peri-implantitis defects in dogs. Three mandibular molars were removed from 1-year-old mongrel dogs. After 2 months of healing, 2 titanium implants with sandblasted with large grit and acid etched (SLA) surface were installed in each side of the mandible. Experimental peri-implantitis was induced with ligatures after successful osseointegration. Ligatures were removed after identification of bone defect beneath the level of 5th thread of fixture on radiographic image. The mucoperiosteal flaps were elevated and the contaminated fixtures were treated with chlorhexidine and saline. The bone defects were assigned to one of the following treatments: no guided bone regeneration (GBR) procedure (group 1), GBR with Bio-$Oss^{(R)}$ and Bio-$Gide^{(R)}$ (group 2), or GBR with toothash - plaster of Paris mixture (TPM) and Bio-$Gide^{(R)}$ (group 3). The dogs were sacrificed after 8 or 16 months. The mean percentages of new bone formation within the limits of the 5 most coronal threads were $17.83{\pm}10.69$ (8 weeks) and $20.13{\pm}13.65$ (16 weeks) in group 1, $34.25{\pm}13.32$ (8 weeks) and $36.33{\pm}14.21$ (16 weeks) in group 2, and $46.33{\pm}18.39$ (8 weeks) and $48.00{\pm}17.78$ (16 weeks) in group 3, respectively. The present study confirmed statistically considerable new bone formation within the threads in group 3 compared with group 1 at 8 and 16 weeks (P<0.05). Although, data analysis did not reveal significant differences between group 2 and 3, the latter showed better results during the period of 8 or 16 weeks. Our findings support the effectiveness of TPM as a GBR material in the treatment of peri-implantitis bone defect.

Enhanced Intra predction for the Characteristics of Color Filter Array (컬러 필터 배열 구조를 고려한 화면 내 예측 개선 기법)

  • Lee, Jae-Hoon;Lee, Chul-Hee
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2012.05a
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    • pp.656-659
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    • 2012
  • In general, images captured by the color filter array are compressed after applying demosaicking process. Since this process introduces data redundancy which can reduce coding efficiency, several methods have been proposed to address this problem. While some conventional approachs convert color format to GBR or YUV 4:2:2 format, we propose to use the YCoCg 4:2:2 format to carry out compression. The proposed method shows an average bits reduction of 3.91% and PSNR increase of 0.04dB compared with H.264 YUV 4:2:0 intra-profile prediction method.

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GUIDED BONE REGENERATION USING $REGENAFORM^{(R)}\;AND\;OSSIX^{(R)}$ MEMBRANE: THREE CASE REPORTS ($Regenaform^{(R)}$$Ossix^{(R)}$ 차단막을 이용한 골유도재생술: 증례보고)

  • Kim, Young-Kyun;Yun, Pil-Young;Lim, Sung-Chul;Kim, Su-Gwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.6
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    • pp.648-653
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    • 2007
  • This case study investigated the clinical effect of guided bone regeneration(GBR) using $Regenaform^{(R)}\;and\;Ossix^{(R)}$ membrane and the histology of the new bone that formed just under the membranes. $Regenaform^{(R)}$ transplantation and covering with $Ossix^{(R)}$ membrane were performed to repair bone defects around implants after implantation in three patients. After $3{\sim}4$ months, the membranes were removed in a second operation, and a biopsy was taken under the membrane. The biopsies showed a bone density of $23{\sim}42%$, and subsequent prosthetic treatments were successful in all cases.

Space-maintaining and osteopromotive effect of freezedried bone graft in the procedure of GBR (동결건조골이 재생공간 유지 및 골재생에 미치는 영향)

  • Hong, So-mi;Herr, Yeek;Kwon, Young-Hyuk;Park, Joon-Bong
    • Journal of Periodontal and Implant Science
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    • v.34 no.1
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    • pp.149-162
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    • 2004
  • This study was performed to evaluate the effect of freeze-dried bone graft on space-making capacity and bone formation in the procedure of guided bone regeneration with titanium reinforced ePTFE membrane. After decortication in the calvaria, GBR procedure was performed on 8 rabbits with titanium reinforced ePTFE membrane filled with human FDBA(Rocky Mountain Tissue Bank,Aurora Co., USA). Decortication was performed to induce the effect of bone forming factor from bone marrow. The animals were sacrificed at 2 weeks, 4 weeks, 8 weeks and 12 weeks after the surgery. Non-decalcified specimens were processed for histologic analysis. πle results of this study were as follows: 1. Titanium reinforced-ePTFE membrane was biocompatable and capable of maintaining the space-making. 2. FDBA particle was surrounded with connective tissues but there was no evidence on new bone formation. 3. FDBA particle resorbed continuously but it remained until 12weeks after the surgery. Within the above results, TR-ePTFE membrane could be used effectively for Guided bone regeneration but It was assumed that FDBA does not appear to contribute to bone formation.

Antioxidant Activities in Germinated and Non-germinated Seeds of Korean Weedy Rice

  • Cho, Ei Ei;Baek, Jung-Sun;Chung, Nam-Jin
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.63 no.3
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    • pp.219-228
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    • 2018
  • Weedy rice (Oryza sativa) is a semi-wild rice grown in paddy fields and is more adapted to the environment than cultivated rice. Therefore, it is expected that the seeds of weedy rice might contain some chemicals related to its environmental adaptation, such as antioxidants, which may be useful for nutritional and medicinal purposes. This study was carried out to investigate the antioxidant activities of weedy rice compared to a Korean-bred rice cultivar, Sindongjin (SDJ), and to screen lines that show higher antioxidant activity in 199 accessions of weedy rice germplasm collected in Korea. DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity ranged from 31.0 to 91.7%, with an average of 82.5%, and 19 accessions that showed more than 91% antioxidant activity were selected. The 19 accessions were re-screened against non-germinated brown rice (BR) and germinated brown rice (GBR) using four assays, total phenol determination, DPPH radical scavenging, ABTS radical scavenging, and reducing power activities. The results showed that accession 'WD3' had the highest antioxidant capacity in both BR and GBR, suggesting that WD3 is a promising potential source of antioxidants and could be developed as a potentially functional substance material.

Physicochemical and textural properties of germinated brown rice according to rice varieties

  • Oh, Sea-Kwan;Cho, Dong-Hwa;Park, Hye-Young;Lee, Seuk-Ki;Choi, Hye-Sun;Park, Jiyoung
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.269-269
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    • 2017
  • Germination is one of the techniques used to enhance the texture properties and nutritional value of the brown rice (BR). Therefore, germinated BR (GBR) has received significant attention during the last decade. Physicochemical and cooking properties of brown rice were examined before and after germination. Germination raised the cooking properties, such as water absorption, expanded volume and soluble solid of cooked BR (brown rice). The texture, measured using tensipresser, was significantly improved by germination. The hardness of cooked BR was decreased by germination, but the GBR was sticker. In RVA, all viscosity value (peak viscosity, break down, set back, and final viscosity) of germinated rice flour was also reduced while gelatinization temperature did not change. Amylose content and amylopectin chain length distribution of BR starch were slightly changed by germination. Overall results revealed that germination was an effective tool to improve texture and cooking properties of BR.

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Development of an Automatic Brown Rice Germinating System of Air-Phase Type with Intermittent Water Spraying and Anion Radiation (간헐 분무와 음이온 방사를 가진 공기노출형 자동 현미발아시스템의 개발)

  • Lim, Ki-Taek;Kim, Jang-Ho;Chung, Jong-Hoon
    • Journal of Biosystems Engineering
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    • v.36 no.3
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    • pp.187-194
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    • 2011
  • In this study an automatic germinating system for germinated brown rice (GBR) was developed for accelerating germination and sprouting of brown rice. With the developed germinating system, the effects of anion radiation treatment on germination ratio, sprout growth, color quality and ${\gamma}$-aminobutyric acid (GABA) content of brown rice were investigated. This system can fast produce GBR by controlling the environmental conditions such as ambient temperature, relative humidity, and proper anion radiation. Air-phase germination with intermittent water spraying improved both germination ratio and sprout growth by about 2.2 and 2.3 times, respectively, compared to the conventional water soaking method. Our results strongly suggest that this germinating system that provides air-phase germination with intermittent water spraying and anion radiation can produce germinated brown rice with good color quality, high GABA content, and fast germination ratio as well as sprout growth.