• Title/Summary/Keyword: GB-index

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A Study on the Effect of Herbal-acupuncture with HK-1000 Solution on Hyperlipidemia and Arteriosclerosis Induced Rats (HK-1000 약침이 흰쥐의 고지혈증 및 동맥경화증에 미치는 영향)

  • Park, Chi-Young;Hong, Kwon-Eui
    • Journal of Pharmacopuncture
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    • v.11 no.3
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    • pp.55-66
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    • 2008
  • Objective&Methods: The purpose of this study is to observe the effects of HK-1000 Herbal-acupuncture solution at GB34(Yangleungchean) on hyperlipidemia and arteriosclerosis in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological change of liver and aorta. Results: 1. HK-1000 herbal-acupuncture infusion increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI(atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/TCL) and the level of TG in serum were increased as compared with those of the control group. 3. In the HK-1000 group, serum AST and ALT were significantly lower than those of the HG group and saline group. 4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. Conclusions: From the above results, it is suggested that HK-1000 herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia and arteriosclerosis.

A Study on the Effect of Herbal-acupuncture with Schizandrae Fructus Solution on Hyperlipidemia in Rats Induced by High Fat Diet (양릉천(陽陵泉) 오미자(五味子)약침이 고지방식이로 유발된 고지혈증 흰쥐에 미치는 영향)

  • Lee, Sung-Hwan;Lee, Hyun
    • Journal of Acupuncture Research
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    • v.28 no.2
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    • pp.143-153
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    • 2011
  • Objectives : The purpose of this study is to observe the effects of herbal acupuncture with Schizandrae Fructus solution at $GB_{34}$(Yangneungcheon) on hyperlipidemia in rats. Methods : In the present study, herbal acupuncture with Schizandrae Fructus solution was administered into hyperlipidemic mice. The author performed several experimental items to analyze the levels of various components and enzymes in serum, liver, as well as the histological changes of liver and aorta. Results : 1. In the Schizandrae Fructus herbal-acupuncture group, serum total cholesterol and Atherogenic index were significantly decreased, and the ratios of HDL to total cholesterol, and phospholipid to total cholesterol in serum were significantly increased as compared with those of the control group. 2. In the Schizandrae Fructus herbal-acupuncture group, HMG-CoA reductase activity was significantly decreased as compared with those of the control group. 3. Schizandrae Fructus herbal-acupuncture reduced deposit of lipid in the liver tissue. Conclusions : From the above results, it is suggested that Schizandrae Fructus herbal-acupuncture at $GB_{34}$ has a therapeutic effect on hyperlipidemia.

The Effect of HK-1001 Pharmacopuncture on Hyperlipidemia Induced Rats (HK-1001 약침이 흰쥐의 고지혈증에 미치는 영향)

  • Kim, Ji-Nam;Hong, Kwon-Eui
    • Journal of Pharmacopuncture
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    • v.11 no.2
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    • pp.41-53
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    • 2008
  • Objective&Methods The purpose of this study is to observe the effects of HK-1001 Pharmacopuncture at GB34(Yangleungchean) on hyperlipidemia in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological changes of liver and aorta. Results 1. HK-1001 Pharmacopuncture infusion solution increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI(atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/TCL) and the level of TG in serum were increased as compared with those of the control group. 3. In the HK-1001 group, serum GOT was significantly lower than those of the HG group and the saline group, and serum ALP was significantly higher than that of the HG group. 4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. Conclusion From the above results, it is suggested that HK-1001 Pharmacopuncture at GB34 has a therapeutic effect on hyperlipidemia.

Implementation of Very Large Hangul Text Retrieval Engine HMG (대용량 한글 텍스트 검색 엔진 HMG의 구현)

  • 박미란;나연묵
    • Journal of Korea Multimedia Society
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    • v.1 no.2
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    • pp.162-172
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    • 1998
  • In this paper, we implement a gigabyte Hangul text retrieval engine HMG(Hangul MG) which is based on the English text retrieval engine MG(Managing Gigabytes) and the Hangul lexical analyzer HAM(Hangul Analysis Module). To support Hangul information, we use the KSC 5601 code in the database construction and query processing stages. The lexical analyzer, parser, and index construction module of the MG system are modified to support Hangul information. To show the usefulness of HMG system, we implemented a NOD(Novel On Demand) system supporting the retrieval of Hangul novels on the WWW. The proposed system HMG can be utilized in the construction of massive full-text information retrieval systems supporting Hangul.

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A Study on the Body Types of Women in the 20's Residing in Shanghai, China (중국 상해지역 20대 전반 여성의 체형연구)

  • Kang, Yeon-Kyung;Sohn, Hee-Soon
    • Journal of Fashion Business
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    • v.12 no.5
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    • pp.24-38
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    • 2008
  • As an attempt to improve the seaming of clothes exported to China, this study is intended to strengthen the clothing industry in Korea by providing data on the body figures of Chinese women. Direct measurement was conducted on 193 women aged 19-24 residing in Shanghai, China. Then we classified and identified the body types and characteristics of Chinese women based on the drop values suggested by the National Standard of the People's Republic of China(GB/T 1335.2-1997). The following is a summary and conclusion of this study. 1. The following results were obtained by measuring the body sizes of women aged 19-24 living in Shanghai, China. 2. After having conducted a factor analysis on 111 body measurement items, 15 index items, and 11 calculation items, we were able to deduce a total of 6 factors. 3. We categorized the body types of 19-24 year-old women living in Shanghai, China according to the drop values suggested by GB/T 1335.2-1997 where D-type was added to Y, A, B, and C-types for a total of 5 categories. The characteristics of each body type following the body type structure factor are Y-type for slender type, A-type for standard type, B-type for slightly large type, and C-type for obese type.

Analysis of the Globular Nature of Proteins

  • Jung, Sung-Hoon;Son, Hyeon-Seok
    • Genomics & Informatics
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    • v.9 no.2
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    • pp.74-78
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    • 2011
  • Numerous restraints and simplifications have been developed for methods that anticipate protein structure to reduce the colossal magnitude of possible conformational states. In this study, we investigated if globularity is a general characteristic of proteins and whether they can be applied as a valid constraint in protein structure simulations with approximated measurements (Gb-index). Unexpectedly, most of the proteins showed strong structural globularity (i.e., mode of approximately 76% similarity to the perfect globe) with only a few percent of proteins being outliers. Small proteins tended to be significantly non-globular ($R^2$=0.79) and the minimum Gb-index showed a logarithmic increase with the increase in protein size ($R^2$=0.62), strongly implying that the non-globular characteristics might be more acceptable for smaller proteins than larger ones. The strong perfect globe-like character and the relationship between small size and the loss of globular structure of a protein may imply that living organisms have mechanisms to aid folding into the globular structure to reduce irreversible aggregation. This also implies the possible mechanisms of diseases caused by protein aggregation, including some forms of trinucleotide repeat expansion-mediated diseases.

Atmospheric Correction of Arc-Rail Type GB-SAR Using Refractive Index of Air (대기 굴절률을 이용한 원형레일 기반 지상 SAR 자료의 대기보정)

  • Lee, Jae-Hee;Kim, Kwang-Eun;Cho, Seong-Jun;Sung, Nak-Hoon;Lee, Hoon-Yol
    • Korean Journal of Remote Sensing
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    • v.28 no.2
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    • pp.237-243
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    • 2012
  • In this paper, an atmospheric effect of repetitive measurements of X-band (9.65 GHz) arc-rail type GB-SAR (ArcSAR) system was quantitatively analyzed. Four artificial triangular trihedral corner reflectors as stationary targets for getting stable back scattered signal during 43 hours continually. The results of the analysis showed that the phase of those stationary targets had changed maximum of 5 radian (12.4 mm) and total RMS error had was 1.62 radian (4 mm) during 65 repeated measuring time. The refractive index of air which was calculated using the temperature;humidity and pressure of atmosphere showed very close relationship with the phase difference. We could check the atmospheric correction was fulfilled by the correction of an atmospheric effect using refractive index during the selected 16 hours period showed that RMS error was dropped from 1.74 radian (4.3 mm) to 0.10 radian (0.24 mm).

Predicting the mortality of pneumonia patients visiting the emergency department through machine learning (기계학습모델을 통한 응급실 폐렴환자의 사망예측 모델과 기존 예측 모델의 비교)

  • Bae, Yeol;Moon, Hyung Ki;Kim, Soo Hyun
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.455-464
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    • 2018
  • Objective: Machine learning is not yet widely used in the medical field. Therefore, this study was conducted to compare the performance of preexisting severity prediction models and machine learning based models (random forest [RF], gradient boosting [GB]) for mortality prediction in pneumonia patients. Methods: We retrospectively collected data from patients who visited the emergency department of a tertiary training hospital in Seoul, Korea from January to March of 2015. The Pneumonia Severity Index (PSI) and Sequential Organ Failure Assessment (SOFA) scores were calculated for both groups and the area under the curve (AUC) for mortality prediction was computed. For the RF and GB models, data were divided into a test set and a validation set by the random split method. The training set was learned in RF and GB models and the AUC was obtained from the validation set. The mean AUC was compared with the other two AUCs. Results: Of the 536 investigated patients, 395 were enrolled and 41 of them died. The AUC values of PSI and SOFA scores were 0.799 (0.737-0.862) and 0.865 (0.811-0.918), respectively. The mean AUC values obtained by the RF and GB models were 0.928 (0.899-0.957) and 0.919 (0.886-0.952), respectively. There were significant differences between preexisting severity prediction models and machine learning based models (P<0.001). Conclusion: Classification through machine learning may help predict the mortality of pneumonia patients visiting the emergency department.

Nanocomposite Cover-layer for NFR Media (Nanocomposite 이용한 NFR Media 커버층 특성연구)

  • Kim, Jin-Hong;Lee, Jun-Seok;Seo, Jeong-Kyo
    • Transactions of the Society of Information Storage Systems
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    • v.3 no.1
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    • pp.17-22
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    • 2007
  • [ $TiO_2$ ] nanoparticles are added into UV curable resin to increase the refractive index of the cover-layer which is laminated on the media for cover-layer incident NFR. High refractive index is required for the cover-layer operating for the solid immersion lens optics with high effective numerical aperture. The eyepattern could be achieved from the cover-layer coated 20 GB ROM disc in which the refractive index of the cover-layer was 1.75, but the gap servo was unstable due to the rough surface of the cover-layer. Even though the light loss due to the nanoparticles is not serious, the rough microstructure is developed by adding the nanoparticles in the organic binder material. To achieve smooth surface for the stable gap servo, some special techniques should be added, for example the solubility of the nanoparticles should be enhanced by the optimization of the surface of the nanoparticles.

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Influence of Dietary Germanium Biotite on Egg Quality and Fecal Noxious Gas Content in Laying Hens (산란계 사료에 게르마늄 흑운모의 첨가가 난각특성 및 분내 유해가스 함량에 미치는 영향)

  • 이원백;김인호;홍종욱;권오석;이상환;민병준;정연권
    • Korean Journal of Poultry Science
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    • v.30 no.1
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    • pp.61-66
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    • 2003
  • This study was conducted to investigate the effects of dietary germanium biotite supplementation on egg quality and fecal noxious gas content in laying hens. One hundred and forty-four 40-wk-old, ISA Brown layers were used in this experiment. Dietary treatments were 1) CON(control diet), 2) GB0.5(control diet + 0.5% germanium biotite), 3) GB1.0 (control diet + 1.0% germanium biotite) and 4) GB1.5(control diet + 1.5% germanium biotite). Hen-day egg Production and egg shell breaking strength were not influenced by germanium biotite supplementation. However, egg weight decrease as the level of germanium biotite supplementation increased in the diets increased(Cubic effect, p<0.02). Eggshell thickness, yolk color and yolk index were not influenced by garmanium biotite supplementation. Serum triglyceride concentration as dietary germanium biotite increased (linear effect P<0.02; quadratic effect, p<0.05). Dietary supplementation of germanium biotite reduced fecal NH$_3$-N concentration (P<0.01), propionic acid(P<0.01), butyric acid( P<0.05) and acetic aicd(P<0.01) concentrations in the feces. In conclusion, the results of this experiment indicated that dietary germanium biotite supplementation did not affect egg shell quality, but reduced fecal NH$_3$-N concentration.