• Journal of Korean Neurosurgical Society
• /
• 제67권3호
• /
• pp.308-314
• /
• 2024

Vein of Galen aneurysmal malformation is one of important pediatric arteriovenous shunt diseases, especially among neonates and infants. Here, early history of the disease identification, basic pathoanatomy with a focus on the embryonic median prosencephalic vein, classification and differential diagnoses, and recent genetic studies are reviewed.

• 의철학연구
• /
• 제25권
• /
• pp.3-26
• /
• 2018

고대세계에서 의학과 철학은 밀접한 관계에 있었다. 소크라테스 이전의 철학자들은 자연학의 일부로 인체에 대한 관심을 갖고 우리 몸의 구성이나 생리적·병리적 현상을 탐구했다. 또 플라톤과 아리스토텔레스는 의학이나 의사, 혹은 질병을 예로 들어 자신들의 철학적 논변을 전개했다. 여기서 철학과 의학은 비유적 차원에서 인간에서 유사한 역할을 하는 두 분야로 설정된다. 그들은 철학은 정념을 제거하여 우리 영혼을 치유하고, 의학은 질병을 제거하여 우리 육체를 치유한다는 점에서 공통적이라고 보았다. 다만 여기서는 의학과 철학의 관계가 유비적 차원에 머물고 있는 문제가 있다. 고대세계에서 의학과 철학의 체계적 결합은 의사-철학자의 전형인 갈레노스를 통하여 전면적으로 이루어졌다. 갈레노스는 의학과 철학의 관련 양상을 그의 글 「좋은 의사는 또한 철학자이다」에서 체계적으로 서술하였다. 갈레노스는 스토아 학파의 철학관을 받아들여 철학을 자연학, 논리학, 윤리학으로 구성된 학문으로 보았다. 따라서 갈레노스에게 좋은 의사는 자연학, 논리학, 윤리학에 정통한 철학자이기도 했다. 그는 의사-철학자의 완벽한 모델을 히포크라테스에게서 찾았다.

• Journal of Korean Neurosurgical Society
• /
• 제50권3호
• /
• pp.191-194
• /
• 2011

Objective : The aim of this study was to analyze the treatment outcome of patients with vein of Galen aneurysmal malformations (VGM). Methods : Clinical and angiographic data of six consecutive patients with VGM were retrospectively reviewed. VGMs were angiographically classified by Yasargil's method. Treatment outcomes were evaluated. Results : Mean age at initial treatment was $4.4{\pm}5.7$ months. Angiographic types of VGMs were type II in two patients and type III in four. Three patients had cardiac symptoms and the others were asymptomatic. Two patients were treated with transvenous embolization, three with transarterial embolization, and one was managed conservatively. Two patients died due to venous hypertension few days after transvenous approach. Of three patients who were transarterially embolized, one was completely occluded with Onyx and two were incompletely occluded. During the follow-up period (range, one to six years) two of three patients treated with transarterial approach were asymptomatic and the other showed mild symptoms. One patient who was managed conservatively showed normal performance. Conclusion : Transarterial embolization of VGMs may be better than transvenous approach in terms of the treatment outcome and complication. Further studies are needed because of the rarity of the disease and rapid advancement of endovascular techniques.

• 정보관리학회지
• /
• 제21권3호
• /
• pp.141-160
• /
• 2004

최근 의학정보 분야에서는 임상의 지식관리와 의학정보 검색의 효율화를 위한 수단으로 온톨로지의 개념 모델링을 이용한 의학용어 시스템에 관심이 모아지고 있다. 본 연구는 우리나라의 의학정보 분야에 이러한 시스템의 응용이나 새로운 시스템 개발애 기초적인 자료제공을 목적으로 , 정보 모델링과 온톨로지의 이론에 대해 고찰하였고, 외국의 의학정보 분양에서 온톨로지를 이용한 용어 시스템이 개발된 4가지 대표적인 사례를 분석하여 비교하였다. 연구결과 비형식적인 수준의 온톨로지로 파악된 MeSH의 의학용어 표준화와 UMLS의 용어 개념화, 형식적인 수준의 온톨로지인 ON9의 의학 온톨로지 통합의 이론화, 그리고 GALEN의 의학지식의 의미 모델과 형식화로 핵심적 특징을 요약할 수 있었다. 온톨로지의 응용은 목적하는 시스템에 따른 수준적 차별화가 이루어져야 하 것이고, 본 연구의 분석 결과가 참고 될 수 있을 것이다.

• Journal of Korean Neurosurgical Society
• /
• 제67권3호
• /
• pp.326-332
• /
• 2024

Intracranial vascular malformations typically encountered by pediatric neurosurgeons include arteriovenous malformations, vein of Galen malformations and cavernous malformations. While these remain amongst some of the most challenging lesions faced by patients and caregivers, the past decade has produced marked advances in the understanding of the pathophysiology of these conditions, with concomitant innovations in treatment. This article will highlight present and future perspectives relevant to these diseases, with a focus on an emerging approach utilizing disease-specific mutations to develop a novel taxonomy for these conditions.

• 대한임상검사과학회지
• /
• 제50권4호
• /
• pp.382-390
• /
• 2018

임신진단검사는 고대 이집트에서 밀과 보리를 이용한 발아시험으로 시작하였다. 이후 Hippocrates와 Galen을 거쳐 uroscopy를 활용하던 중세를 넘어 1800년대 초반까지도 비과학적 방법들이 사용되었다. 그러나 1800년대 중반 이후 과학적 실험방법과 근거들이 나타나기 시작하면서 임신의 생리학적 특성에 대한 과학적 연구들이 시작되었다. 이와 같은 과학적 연구결과를 활용하려는 최초 시도는1927년 Aschheim와 Zondek의 rat와 mouse를 이용한 bioassay로 시작되었고, 이후 토끼와 개구리를 이용하는 실험으로 발전하였다. 1960년대부터 시작된 면역검사방법은 bioassay의 문제점을 개선하면서 임신진단검사를 일반화하는데 크게 기여하였다. 1976년에는 가정에서 사용할 수 있는 임신진단키트가 출시되어 임신진단을 대중화하는데 기여하였다. 1980년대 이후 진단검사의 기술적 진보는 임신진단검사에도 활용되어 임신진단의 검사신뢰도는 더욱 향상되었으며, 2000년대에는 가정용 임신진단키트의 정확도와 사용편리성이 혁신적으로 향상되었다. 본 조사에서는 임신진단검사의 역사와 과학적 발전과정을 고찰하였다.

• 대한의료기공학회지
• /
• 제12권1호
• /
• pp.50-77
• /
• 2011

The social demand of manipulative therapy has increased. but the concept, terminology, classification and system of manipulative therapy is unclear. Therefore, academic organization on manipulative therapy is needed. The aim of this study is overview the evolution of manipulative therapy and based on this, we will find out how manipulative therapy is studied in South Korea. Manipulative therapy reflects medical knowledge and trends at the time. Historically people who work as key roles in evolution of manupulative therapy are Hippocrates, Claudius Galen, Acicenna(Ibn Sīnā), Ambroise Paré, Andreas Vesalius, Pehr Henrik Ling, Florence Nightingale, Andrew Taylor Still, Daniel David Palmer, James Beaver Mennell, James Henry Cyriax, Robin Mckenzie, Freddy Kaltenborn, Brian R Mulligan, George Goodheart, Mikao Usui, Wilhelm Reich, Ida Rolf. As the result of articles search, Massage, Chiropractics, acupressure(acupuncture), Chuna, osteopathy, reflexology, CST, Mulligan techniques, Dongbang whalbub, Kaltenborn-Evjenth orthopedic manual therapy are major subject that studied in South Korea.

• 한국정보처리학회:학술대회논문집
• /
• 한국정보처리학회 2010년도 추계학술발표대회
• /
• pp.465-465
• /
• 2010

A controlled medical vocabulary is a vital component of medical information management because it enables computers to use information meaningfully and different institutions to share the medical data. There are currently many standard medical vocabularies - SNOMED-CT, ICD-10, UMLS, GALEN, MED, etc, but none is universally accepted as an optimal controlled medical vocabulary for application to medical information system. Moreover, it is difficult to settle the well-designed local data dictionary consisting of controlled medical vocabularies for the individual hospital information system (HIS). One of the major reasons is the local terminology with poor contents have been used in the hospital. Thus, as a trial, the local controlled vocabulary referencing system has being constructed in a limited medical field - nuclear medicine. We selected practical nuclear medicine terms from interpretation reports and electronic medical records, and removed ambiguity and redundancy, mapping the selected terms to standard medical vocabularies. Relationship and hierarchy structure between terms have being made, referring to standard medical vocabularies. Further studies may be warranted.

• 한국신재생에너지학회:학술대회논문집
• /
• 한국신재생에너지학회 2009년도 춘계학술대회 논문집
• /
• pp.744-744
• /
• 2009

The development of safe and suitable hydrogen storage materials is one of key issues for commercializing hydrogen as an energy carrier. Carbon based materials have been investigated for many years to store hydrogen by the adsorption of the gas on the surface of the carbon structure. Recently, it is reported that carbon nitride nanobells have high hydrogen storage capacity since the nitrogen atom plays an important role on attracting hydrogen molecules. Here we report carbon nitride microporous spheres (CNMS) which have the maximum surface area of 995.3 $m^2/g$. Melamine-Formaldehyde resin is the source of carbon and nitrogen in CNMS. Most of the CNMS pores have diameters in the range of 6 to 8 A which could give a penetration energy barrier to a certain molecule. In addition, the maximum hydrogen storage capacities of carbon nitride spheres are 1.9 wt% under 77 K and 1 atm.

• Journal of Korean Neurosurgical Society
• /
• 제29권6호
• /
• pp.815-821
• /
• 2000

Parasplenial arteriovenous malformations(AVMs) are rare vascular malformations which have distinct clinical and anatomical features. They are situated at the confluence of the hippocampus, isthmus of the cingulate gyrus and the gyrus occipitotemporalis medialis. These lesions are anterior to the calcarine sulcus and their apex extends towards the medial surface of the trigonum. Posterolaterally, these lesions are in close proximity to the visual cortex and optic radiation. The objectives in the surgery of parasplenial AVMs are complete resection of the lesions and preservation of vision. These objectives must be achieved with comprehensive understanding of the following anatomical features :1) the deep central location of the lesions within eloquent brain tissue ; 2) the lack of cortical representation of the AVMs that requires retraction of visual cortex ; 3) deep arterial supply ; 4) deep venous drainage ; 5) juxtaposition to the choroid plexus with which arterial supply and venous drainage are shared. A 16-year-old female student presented with intraventricular hemorrhage from a right parasplenial-subtrigonal AVM. The lesion, fed by posterior cerebral artery and drained into the vein of Galen, was successfully treated by the inter-hemispheric parietooccipital approach. To avoid visual field defect a small incision was made on precuneus anterior to the calcarine sulcus. In this report, the authors describe a surgical approach with special consideration on preservation of visual field.