• Journal of Korean Neurosurgical Society
• /
• v.67 no.3
• /
• pp.308-314
• /
• 2024

Vein of Galen aneurysmal malformation is one of important pediatric arteriovenous shunt diseases, especially among neonates and infants. Here, early history of the disease identification, basic pathoanatomy with a focus on the embryonic median prosencephalic vein, classification and differential diagnoses, and recent genetic studies are reviewed.

• Philosophy of Medicine
• /
• v.25
• /
• pp.3-26
• /
• 2018

Medicine and philosophy were very closely related in antiquity. The Pre-Socratics were interested in physiological and pathological aspects of human body. Their interests of human body was a part of interests on nature. Plato and Aristotle were fond of proposing their philosophical arguments using medical analogy. Medicine and philosophy were regarded as two disciplines which play a similar role in human being. Ancient philosophers thought that medicine and philosophy were similar on the ground that while philosophy eliminates passion from human soul, medicine eliminates disease from human body. Here, they regarded the similarity of medicine and philosophy only in terms of analogy. More comprehensive and systematic relationship between medicine and philosophy is realized by Galen. He manifestly declared that "The Best Doctor is also a Philosopher", which is also the title of one of his treatise. In this treatise, Galen regarded philosophy is a discipline consisted of physics, logic, and ethics according to the view s of Stoics. As a result, a good doctor for Galen is one who is well versed in physics, logic, and ethics. Furthermore, He regarded Hippocrates as the ideal model of a doctor-philosopher.

• Journal of Korean Neurosurgical Society
• /
• v.50 no.3
• /
• pp.191-194
• /
• 2011

Objective : The aim of this study was to analyze the treatment outcome of patients with vein of Galen aneurysmal malformations (VGM). Methods : Clinical and angiographic data of six consecutive patients with VGM were retrospectively reviewed. VGMs were angiographically classified by Yasargil's method. Treatment outcomes were evaluated. Results : Mean age at initial treatment was $4.4{\pm}5.7$ months. Angiographic types of VGMs were type II in two patients and type III in four. Three patients had cardiac symptoms and the others were asymptomatic. Two patients were treated with transvenous embolization, three with transarterial embolization, and one was managed conservatively. Two patients died due to venous hypertension few days after transvenous approach. Of three patients who were transarterially embolized, one was completely occluded with Onyx and two were incompletely occluded. During the follow-up period (range, one to six years) two of three patients treated with transarterial approach were asymptomatic and the other showed mild symptoms. One patient who was managed conservatively showed normal performance. Conclusion : Transarterial embolization of VGMs may be better than transvenous approach in terms of the treatment outcome and complication. Further studies are needed because of the rarity of the disease and rapid advancement of endovascular techniques.

• Journal of the Korean Society for information Management
• /
• v.21 no.3
• /
• pp.141-160
• /
• 2004

Recent reseach in the field of medical information systems has paid much attention to an ontology based medical terminology system to support clinical study and effective information search. This study aims to conduct research for further application or construction of ontology systems in Korea. This research reviews the theory of concept modeling and ontology. and analyses 4 cases of conceptual modeling of medical tenrminologies by ontology, The findings ot this study display these specific characteristics in medscal ontologies: (UHe standardization of terrrinology on MeSH. (2) The conceptualization of tenninology on UMLS. (l) ane. (2) are showed as untormal ontologies. (3) The theory of ontology integration in ON9, (4) The reference model of medical knowledge with formalization in GALEN. (3) and (4) are showed as formal ontologies. The application and construction of ontology should be differentiated according to the level of the proposed system, and then this analysis will provide useful information for the researcher and developer of the system.

• Journal of Korean Neurosurgical Society
• /
• v.67 no.3
• /
• pp.326-332
• /
• 2024

Intracranial vascular malformations typically encountered by pediatric neurosurgeons include arteriovenous malformations, vein of Galen malformations and cavernous malformations. While these remain amongst some of the most challenging lesions faced by patients and caregivers, the past decade has produced marked advances in the understanding of the pathophysiology of these conditions, with concomitant innovations in treatment. This article will highlight present and future perspectives relevant to these diseases, with a focus on an emerging approach utilizing disease-specific mutations to develop a novel taxonomy for these conditions.

• Korean Journal of Clinical Laboratory Science
• /
• v.50 no.4
• /
• pp.382-390
• /
• 2018

The history of the pregnancy test started in ancient Egypt with a germination test using wheat and barley. Since then, unscientific methods have been used from the days of Hippocrates and Galen to the Middle Ages when uroscopy was used, even until the early 1800s. On the other hand, since the mid-1800s, scientific methods and evidence have begun to emerge, which led to scientific research on the physiological characteristics of pregnancy. The first attempt to utilize these scientific findings was initiated with the bioassay by Aschheim and Zondek using rats and mice in 1927, and then developed into experiments using rabbits and frogs. The immunoassay method, which started in the 1960s, contributed greatly to the generalization of the pregnancy tests while improving the problems of the bioassay. In 1976, a pregnancy test kit was introduced that can be used at home, contributing to the popularization of pregnancy tests. Since the 1980s, technological advances in diagnostic tests have also been applied to pregnancy tests to further improve the reliability of the diagnosis of pregnancy. In the 2000s, the accuracy and ease of use of the pregnancy test kits for home use have improved drastically. This study examined the history and scientific development of the pregnancy test.

• Journal of Korean Medical Ki-Gong Academy
• /
• v.12 no.1
• /
• pp.50-77
• /
• 2011

The social demand of manipulative therapy has increased. but the concept, terminology, classification and system of manipulative therapy is unclear. Therefore, academic organization on manipulative therapy is needed. The aim of this study is overview the evolution of manipulative therapy and based on this, we will find out how manipulative therapy is studied in South Korea. Manipulative therapy reflects medical knowledge and trends at the time. Historically people who work as key roles in evolution of manupulative therapy are Hippocrates, Claudius Galen, Acicenna(Ibn Sīnā), Ambroise Paré, Andreas Vesalius, Pehr Henrik Ling, Florence Nightingale, Andrew Taylor Still, Daniel David Palmer, James Beaver Mennell, James Henry Cyriax, Robin Mckenzie, Freddy Kaltenborn, Brian R Mulligan, George Goodheart, Mikao Usui, Wilhelm Reich, Ida Rolf. As the result of articles search, Massage, Chiropractics, acupressure(acupuncture), Chuna, osteopathy, reflexology, CST, Mulligan techniques, Dongbang whalbub, Kaltenborn-Evjenth orthopedic manual therapy are major subject that studied in South Korea.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2010.11a
• /
• pp.465-465
• /
• 2010

A controlled medical vocabulary is a vital component of medical information management because it enables computers to use information meaningfully and different institutions to share the medical data. There are currently many standard medical vocabularies - SNOMED-CT, ICD-10, UMLS, GALEN, MED, etc, but none is universally accepted as an optimal controlled medical vocabulary for application to medical information system. Moreover, it is difficult to settle the well-designed local data dictionary consisting of controlled medical vocabularies for the individual hospital information system (HIS). One of the major reasons is the local terminology with poor contents have been used in the hospital. Thus, as a trial, the local controlled vocabulary referencing system has being constructed in a limited medical field - nuclear medicine. We selected practical nuclear medicine terms from interpretation reports and electronic medical records, and removed ambiguity and redundancy, mapping the selected terms to standard medical vocabularies. Relationship and hierarchy structure between terms have being made, referring to standard medical vocabularies. Further studies may be warranted.

• 한국신재생에너지학회:학술대회논문집
• /
• 2009.06a
• /
• pp.744-744
• /
• 2009

The development of safe and suitable hydrogen storage materials is one of key issues for commercializing hydrogen as an energy carrier. Carbon based materials have been investigated for many years to store hydrogen by the adsorption of the gas on the surface of the carbon structure. Recently, it is reported that carbon nitride nanobells have high hydrogen storage capacity since the nitrogen atom plays an important role on attracting hydrogen molecules. Here we report carbon nitride microporous spheres (CNMS) which have the maximum surface area of 995.3 $m^2/g$. Melamine-Formaldehyde resin is the source of carbon and nitrogen in CNMS. Most of the CNMS pores have diameters in the range of 6 to 8 A which could give a penetration energy barrier to a certain molecule. In addition, the maximum hydrogen storage capacities of carbon nitride spheres are 1.9 wt% under 77 K and 1 atm.

• Journal of Korean Neurosurgical Society
• /
• v.29 no.6
• /
• pp.815-821
• /
• 2000

Parasplenial arteriovenous malformations(AVMs) are rare vascular malformations which have distinct clinical and anatomical features. They are situated at the confluence of the hippocampus, isthmus of the cingulate gyrus and the gyrus occipitotemporalis medialis. These lesions are anterior to the calcarine sulcus and their apex extends towards the medial surface of the trigonum. Posterolaterally, these lesions are in close proximity to the visual cortex and optic radiation. The objectives in the surgery of parasplenial AVMs are complete resection of the lesions and preservation of vision. These objectives must be achieved with comprehensive understanding of the following anatomical features :1) the deep central location of the lesions within eloquent brain tissue ; 2) the lack of cortical representation of the AVMs that requires retraction of visual cortex ; 3) deep arterial supply ; 4) deep venous drainage ; 5) juxtaposition to the choroid plexus with which arterial supply and venous drainage are shared. A 16-year-old female student presented with intraventricular hemorrhage from a right parasplenial-subtrigonal AVM. The lesion, fed by posterior cerebral artery and drained into the vein of Galen, was successfully treated by the inter-hemispheric parietooccipital approach. To avoid visual field defect a small incision was made on precuneus anterior to the calcarine sulcus. In this report, the authors describe a surgical approach with special consideration on preservation of visual field.