• Journal of Astronomy and Space Sciences
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• 제18권3호
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• pp.239-248
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• 2001

2002년에 발사 예정인 과학 위성 1호의 주 탑재체로 원자외선 분광기가 실릴 예정이다. 원자외선 분광기는 영상과 분광의 기능을 함께 수행하게 되는데, 광학 부품 중 포물 원통 만가경의 경우 천문 관측용으로는 제작된 바가 없어 제작과 이에 관련된 측정 방법을 새로이 고안하여 제작시험이 이루어 겼다. 관측 목표로부터 도출된 사양 중에서 성능과 가장 밀접한 관계가 있는 형상오차의 경우 ~ $lambda/cm$의 한계를 만족하였으며, 산란장과 연관된 표면 거칠기의 경우 새로이 고안된 비구면 pitch polishing의 방법으로 $R_{q}$의 값이 1 nm 이하로 감소하였으며, 이로써 전체 파장 영역에서 0.02, 즉 2% 미만의 빛이 산란됨을 간접적으로 확인하였다.

• 정보관리학회지
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• 제37권2호
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• pp.197-223
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• 2020

본 연구는 통합서지용 한국문헌자동화목록(KORMARC)으로 작성된 서지레코드를 FRBR의 저작(Work) 단위로 군집화하는 과정에서 나타난 이슈사항들을 분석하고, 이에 대한 해결방안을 고안하였다. 특히 기존의 연구에서는 대표저작자를 식별하고 처리하는 기준이 명확하게 드러나지 않거나 파생저작 레코드의 대표저작자를 선정하는 방법에 대한 논의가 충분히 이루어지지 않았다. 따라서 본 연구는 저작을 창작하는 데 기여한 사람이 다수일 때 대표저작자를 명확하게 식별하기 위한 방법을 고안하는 데 초점을 맞추었다. 이를 위해 책임표시사항(245) 필드의 책임표시 태그(▼d, ▼e)에서 추출한 역할용어를 토대로 표준화된 저자역할용어사전을 개발하여 대표저작자 판별에 활용하는 방안을 마련하였다. 또한 저자명의 유사도와 표제의 유사도를 각각 계산하여 유사도가 일정 수준 이상인 경우 동일한 저작으로 군집화 하는 방법을 채택하였다. 각각의 유사도를 계산하여 동일 저작을 판단하므로 공백, 관제처리, 괄호제거와 같은 데이터 정제 조건을 조정하여 6가지 패턴에 따른 군집화의 정확도를 비교하였고, 저자명과 표제의 유사도가 모두 80퍼센트 이상일 때의 정확도가 가장 높게 나타났다. 본 연구는 대표저작자 선정을 위한 역할용어사전 개발, 대표저작자와 표제의 유사도를 별도로 측정하여 저작군집화를 시도한 실험연구이며 후속 연구에서는 표제 간 유사도 측정의 정확도를 향상시키는 방안과 FRBR 1그룹의 다른 개체(표현형, 구현형, 개별자료) 수준으로 확대하여 활용하는 방안, 국내에서 사용하고 있는 다른 형태의 MARC 데이터에 적용하는 방안을 고안할 예정이다.

• Journal of Nutrition and Health
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• 제42권8호
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• pp.673-681
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• 2009

Diabetes mellitus is a multifactorial disease. Particularly, diabetic nephropathy is a serious complication for diabetic patients, yet the precise mechanisms that underline the initial stage of diabetic renal inflammation remain unknown. However, oxidative stress induced by hyperglycemia in diabetes is implicated in diabetic renal disease. We hypothesized that dietary supplementation of antioxidants either VCE (0.5% VC + 0.5% VE) or Comb (0.5% VC + 0.5% VE + 2.5% N-acetylcysteine) improves acute diabetic renal inflammation through modulation of blood glucose levels and antioxidant and anti-inflammatory responses. Experimental animals (5.5 weeks old female ICR) used were treated with alloxan (180 mg/kg) once. When fasting blood glucose levels were higher than 250 mg/dL, mice were divided into 3 groups fed different levels of antioxidant supplementation, DM (diabetic mice fed AIN 93G purified rodent diet); VCE (diabetic mice fed 0.5% vitamin C and 0.5% vitamin E supplemented diet); Comb (diabetic mice fed 0.5% vitamin C, 0.5% vitamin E and 2.5% N-acetylcysteine supplemented diet), for 10 days and then sacrificed. Body weights were measured once a week and blood glucose levels were monitored twice a week. Lipid peroxidation products, thiobarbituric acid reacting substances were measured in kidney. NF-${\kappa}B$ activation was indirectly demonstrated by pI${\kappa}B$-${\alpna}$ and expressions of selective inflammatory and oxidative stress markers including antioxidant enzymes were also determined. Dietary antioxidant supplementation improved levels of blood glucose as well as kidney lipid peroxi-dation. Dietary antioxidant supplementation improved NF-${\kappa}B$ activation and protein expression of HO-1, but not mRNA expression levels in diabetic mice fed Comb diet. In contrast, the mRNA and protein expression of CuZnSOD was decreased in diabetic mice fed Comb diet. However, antioxidant supplementation did not improve mRNA and protein expressions of IL-$1{\beta}$ and MnSOD in diabetic mice. These findings demonstrate that acute diabetic renal inflammation was associated with altered inflammatory and antioxidant responses and suggest that antioxidant cocktail supplementation may have beneficial effects on early stage of diabetic nephropathy through modulation of blood glucose levels and antioxidant enzyme expressions.

• 한국토양비료학회지
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• 제49권6호
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• pp.795-806
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• 2016

This study was conducted to improve the continuous techniques for international competitiveness of ginseng industry to Korea-China FTA negotiation and conclusion, and provide the basic information for ginseng industry development of Korea. It was carried out the visiting of the northeastern three provinces (Jilin, Liaoling and Heilongjang) in China for 3-year from 2014 to 2016 and observed the farmers' fields of ginseng cultivation with soil environmental status. The types of ginseng cultivation could be observed in small scales of 0.5~3.0 ha, in middle scales of 4.0~10.0 ha and in large scales of 30~700 ha with the kinds of imhasam, Chinese ginseng, Korean ginseng and western ginseng. Also ginseng was cultivated in newly reclaimed land of forest in two types of direct seeding and transplanting of ginseng seedlings. The field beds of ginseng growing were covered with vinyl films in arch design of 100~130 cm height and vinyl was painted in spraying with blue, green and yellow colours for shading. It was investigated in status of the physico-chemical properties of soils. The physical information on the field soils were silt loam, loam and sandy loam in soil textures, and some plain in low slope, some alluvial fan or local valley in forest of land topography. Soil pH ranged within 5.0~5.2, soil EC was $0.93{\sim}3.78dS\;m^{-1}$, organic matter was $37{\sim}35g\;kg^{-1}$, nitrate nitrogen $63{\sim}490mg\;kg^{-1}$, available $P_2O_5$ $55{\sim}163mg\;kg^{-1}$, and in exchangeable cations, K was 0.30~0.98, Ca was 6.5~14.0, Mg was $1.1{\sim}5.3cmol_c\;kg^{-1}$ in ranges. Farmers used the fertilizer for ginseng cultivation in 10~11 t of compost, $200{\sim}400kg\;ha^{-1}$ of complex fertilizer and $750kg\;ha^{-1}$ of oil cakes. The northeastern three provinces of China can use the newly lands with large areas of ginseng cultivation in soil sickness by continuous cropping. and the soil basic fertility is batter than that of Korean in standard guide of ginseng cultivation soil.

• Fisheries and Aquatic Sciences
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• 제5권3호
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• pp.229-234
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• 2002

Possibility of raising sunshine bass during the winter season in Korea was investigated. Also, the effect of feed on growth and body composition of sunshine bass was compared at the various salinity. Twenty sunshine bass $(Mean\;weight\;\pm S.D.\: :\;53.9 \pm 0.24 g)$ were stocked into the eighteen circular flow-through tanks. A 2 (feed) $\times$ 3 (salinity) factorial design with triplicate was used for this study. Feed was prepared into the 2 groups: the raw fish-based me>ist pellet (MP) containing $59.5\%$ crude protein and $9.4\%$ crude lipid, and commercial sinking red sea bream feed (CF) containing $49.9\%$ crude protein and $9.4\%$ crude lipid, respectively. And salinity was prepared into the 3 groups: freshwater $(0\%)$, brackishwater $(15\%)$, and seawater $(32\%)$. Fish were fed to satiation twice daily for 6 days a week. Fish were all survived at the end of the 8-week feeding trial. Weight gain (WG) and specific growth rate (SGR) of sunshine bass were significantly (P<0.05) affected by both feed and salinity. WG and SGR of sunshine bass fed the MP were significantly (P<0.05) higher than those of fish fed the CF in the same salinity. Amount of dry feed fed was significantly (P<0.05) affected by both feed and salinity. Feed consumption by sunshine bass fed on the MP was significantly (P<0,05) higher than by fish fed on the CF in the same salinity. Feed efficiency ratio (FER) was significantly (P<0,05) affected by salinity, but not by feed. Protein efficiency ratio (PER) was significantly (P<0.05) affected by both feed and salinity. Moisture and protein content of the whole-body of fish was not significantly (P>0.05) affected by either feed or salinity. However, lipid and ash content of the whole-body of fish was significantly (P<0.05) affected by salinity, but not by feed. In conclusion, the MP was superior to CF for growth of sunshine bass during the winter season in Korea and no mortality occurred. And sunshine bass seemed to grow better in freshwater $(0\%)$ and brac-kishwater $(15\%)$ than seawater $(32\%)$ under these experimental conditions, in terms of improvement in FER and PER in freshwater or brackishwater.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.815-822
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• 2015

Purpose: In this study, we aimed to evaluate the effects of sex-based non-small cell lung cancer (NSCLC) varieties on survival rates. Materials and Methods: A retrospective study was performed in patients with NSCLC who were diagnosed by histological methods between the years 2000 and 2010. A chi-square test was used to compare variables. Overall survival (OS) was estimated by the Kaplan-Meier method. Results: Of the 844 patients, 117 (13.9%) were women and 727 (86.1%) were men. Adenocarcinoma was more common in women than in men (p<0.0001). There were more women non-smokers than men (p<0.0001). There was no statistically significant difference in ECOG PS, weight loss>10%, stage, LDH, albumin and treatment between women and men. Women younger than 65 years (17.0 vs 12.0 months; p=0.03), who had adenocarcinoma histology (15.0 vs 10.0 months; p=0.006) and who had a hemoglobin level ${\geq}12g/dL$ (18.0 vs 12.0 months; p=0.01) were found to have a better median OS rate than men. Median OS rates were found to be 13.0 months in females and 12.0 months in males (p=0.14). Among metastatic patients, the median OS was 11.0 months in females and 8.0 months in males (p=0.005). Among stage IIIB and stage IV patients who had first line platinum-based chemotherapy, the median OS was 17.0 months in women and 11.0 months in men (p=0.002). The response rate of chemotherapy was higher in women than in men (p=0.03). Conclusions: In our study, we found that survival duration is longer and chemotherapy response is better in women with NSCLC who do not have anemia or comorbidities and who are mostly non-smokers with adenocarcinomas. Further studies regarding the causes of these differences may provide clarity on this subject.

• 마이크로전자및패키징학회지
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• 제22권2호
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• pp.61-68
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• 2015

박형 package-on-package의 상부 패키지와 하부 패키지에 대하여 에폭시 몰딩 컴파운드(EMC)에 따른 warpage 특성을 분석하였다. 또한 동일한 EMC로 몰딩한 패키지들의 warpage 편차를 측정하고 박형 상부 기판과 하부 기판 자체의 warpage 편차를 측정함으로서, 박형 패키지에서 warpage 편차를 유발하는 원인을 분석하였다. 박형 기판을 사용한 상부 및 하부 패키지에서는 기판 자체의 큰 warpage 편차에 기인하여 EMC의 물성이 패키지의 warpage에 미치는 영향을 규명하는 것이 어려웠다. EMC의 몰딩 면적이 $13mm{\times}13mm$로 기판($14mm{\times}14mm$)의 대부분을 차지하는 상부 패키지에서는 온도에 따른 warpage의 변화 거동이 유사하였다. 반면에 EMC의 몰딩 면적이 $8mm{\times}8mm$인 하부 패키지의 경우에는 (+) warpage와 (-) warpage가 한 시편에 모두 존재하는 복합적인 warpage 거동에 기인하여 동일한 EMC로 몰딩한 패키지들에서도 상이한 온도-warpage 거동이 측정되었다.

• 한국식품영양과학회지
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• 제33권4호
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• pp.653-658
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• 2004

Wistar계 흰쥐에게 두릅열수추출물을 7주간 급여하였으며 당뇨유발은 희생 2주전 streptozotocin을 투여하여 혈당이 300 mg/dL 이상인 흰쥐를 대상으로 유해 활성 산소 대사계에 미치는 영향을 구명하였다. 간조직 중의 유해 활성산소 생성계인 P-450 함량과 XO 및 AD 활성은 정상군에 비하여 당뇨대조군에서 유의적으로 감소된 반면, AH 활성은 증가 되었다. 두릅열수추출물 급여로 이들 유해 활성 생성계 효소 활성 변화가 완화되는 것으로 나타났다. 또한 SOD, CAT, GSH-Px 및 GST, GR과 같은 유해 활성산소 제거계와 G6PD 효소들은 당뇨유발로 유의적인 증가를 보였으나, 두릅열수추출물 급여군에서는 이들 효소 활성이 낮았다. 당뇨유발로 항산화물질인 글루타티온 함량은 유의적으로 감소된 반면 지질과산화물 생성은 유의적으로 증가되었다. 그러나 두릅열수추출물 급여는 당뇨대조군의 이들 함량 변화를 유의적으로 억제하는 것으로 나타났다. 이상의 결과에서 두릅열수추출물 급여는 STZ 투여로 인한 유해 활성산소 대사계 변화를 완화시킬 뿐만 아니라 지질과산화물 생성을 억제함으로써 산화적 스트레스로 인한 당뇨합병을 예방할 수 있을 것으로 사료된다.

• 한국환경과학회지
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• 제13권1호
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• pp.99-107
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• 2004

This research is to determine the level of environmental pollution at a blasting construction area which is the origin of noise, vibration, and suspended particle, and to compare the results with other domestic and international standard data. This experiment is also to find out the effects resulting from blasting construction and to propose a plan that can decrease environmental pollution. The blasting construction area is a factory site which is about one and half million square meter and sewage disposal plant is about ninety thousand square meter. Both were selected as the areas for the tests to be conducted in determination test. The test to determine the level of noise, vibration, and total suspended particle was conducted thirty times around the blasting construction area by comparing measurement results and numerical analysis. However, as the test was not conducted in the laboratory but in the actual blasting construction area, it was not possible to do the test with the same exact conditions each true. Therefore, the test was not ideal as conditions could change from test to test. For the most part, the level of noise was below the standard level of 70dB. Every vibration test was under the standard limitation. For example, a house, 200m away was tested for noise and vibration and the level was found to be under the 0.2 cm/sec which is the standard for specialty designed cultural sites., i.e very low level. Also a buried oil pipeline that was 30m away also marked under 2.0cm/sec which is the norm for an industrial area. However, if there were an oil pipeline under the house, the amount of charging gunpowder per hole should be decreased compared to the amount used in the test. The test result for suspended particles under the standard limitation which is 24hour average 300$\mu\textrm{g}$/㎥ at a distance from blasting wavelength, but at detonator, total suspended particle from the blast origin exceeded the standard limitation. If explosion occurs when it detonates in the hole, most of the energy would be absorbed in the crushing of rocks, but some remaining energy would make noises and vibration inevitable. So the important thing is how to minimize the environmental pollution from the blasting. There should be regulations in order that the standard limitation is not exceeded, and to decrease the environmental pollution from the blasting.

• 대한치과보철학회지
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• 제32권1호
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• pp.77-102
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• 1994

Many studies have been made on the masticatory and esthetic effects of prosthodontic treatments, but few on the restoration of pronunciation, especially in complete denture wearers. The purpose of this study is to provide a basis that could be of help to the complete denture wearers' speech adaptation by analyzing the influence of the palatal coverage upon the duration of consonants and vowels with the method of experimental phonetics. For this study, metal plates and resin plates were made for 3 male subjects in their twenties, who have good occlusion, and do not have speech and hearing disorders. Then 8 Korean consonants and 4 Korean vowels were selected, systemically considering phonetic variants such as the place and manner of articulation, lenis/fortis, mutual effect of each phoneme, etc. They were combined into meaningless tested words in the form of /VCV/, and were included in the carrier sentences. Each informant uttered the sentences 1) without the plate, 2) with the metal plate, 3) with the resin plate. The recorded data were analyzed through the waveform of sounds and spectrogram by using the program SoundEdit, Signalize, Statview 512+for the Macintosh computer. The duration of each segment was measured by searching for the boundaries between the preceding vowels and consonants, and between the consonants and the following vowels. The study led to the conclusion that. 1. With the palatal plate, the duration of all the tested words increased and the duration increased more with the resin plate than with the metal plate. 2. With the palatal plate, the duration of all the preceding vowels, consonants, and following vowels increased, but the temporal structure of the tested words was maintained. 3. As for the manner of articulation, fricative /s/(ㅅ) was greatly influenced by both kinds of palatal plates. 4. As for the place of articulation, alveolar sounds /d/(ㄷ), /n/(ㄴ) were greatly influnced by the kinds of palatal plates, and the velar sounds /n/(ㅇ), /g/(ㄱ) were influenced by the platal plates, but the kind of the palatal plates did not show any significance. 5. As for the lenis/fortis, lenis was influenced more by the kind of the palatal plates. 6. As for the influence of vowels upon each segment in the tested words, palatal vowel /i/(ㅣ) had greater influence than pharyngeal vowel /a/(ㅏ), and following vowels than preceding vowels.