• 대한치과의사협회지
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• 제12권4호
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• pp.269-273
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• 1974

This present investigation was concerned with the content of ash, Mg, Ca, K and N'a of bone, cartilage, incisor teeth and molar teeth in rats of different weights. The results obtained were summarized as follows. 1. Cartilage is the most adequate model for the study in vivo of mechanisms concerned with normal calcification. 2. The percentage of inorganic material in cartilage rose from approx 13% of the dry weight in 5g rat to 46% in the tissue from rats weighing 134g 3. There was no marked change in the content of ash, Ca, Mg, K and Na after eruptions due to the increasing weight.

• 폴리머
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• 제28권4호
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• pp.328-334
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• 2004

단백질 전달체로 이용하기 위한 폴리(에틸렌 글리콜)-폴리(락타이드-co-글리콜라이드) 공중합체는 카비톨 (134 g/mole)과 550, 2000 및 5000g/mole의 각기 다른 분자량을 가진 메톡시 폴리(에틸렌 글리콜)을 개시제로 하여 촉매인 Sn(Oct)$_2$를 사용하여 L-락타이드와 글리콜라이드의 개환중합에 의해 합성되었다. $^1$H-NMR, GPC, 그리고 XRD를 이용하여 합성된 블록 공증합체의 특성을 결정하였다. 이식형 웨이퍼를 준비하기 위하여 동결분쇄기를 이용하여 형광이 결합된 1% 소 혈청 알부민과 고분자를 균일 혼합 후에 3mm${\times}$1mm의 크기로 웨이퍼를 제조하였다. 형광 알부민의 방출 거동과 pH 변화는 pH 7.4의 인산염완충용액을 이용하여 37$^{\circ}C$, 100rpm의 항온조에서 30일 동안 관찰하였다. 알부민의 방출양은 형광분광기를 통하여 FITC의 강도에 의해 결정되었다. 알부민의 방출 거동은 블록 공중합체내에서 MPEG의 분자량이 증가할수록 빠른 초기방출을 보였고, PLGA의 분자량을 조절함으로서 약물의 방출기간을 결정할 수 있었다. 이러한 결과로 생분해성 PLGA에 친수성인 MPEG의 도입을 통해 약물의 방출거동을 조절할 수 있었다.

• Asian-Australasian Journal of Animal Sciences
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• 제10권1호
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• pp.134-140
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• 1997

Objectives of this study were to determine effects of insulin on acetyl-CoA carboxylase (ACC) activity and correlate this activity with relative amounts of ACC in MAC-T cells. MAC-T cells were grown in Medium 199 supplemented with fetal bovine serum (5%), cortisol ($1{\mu}g/ml$), and insulin ($1{\mu}g/ml$). At confuluence, the cells were transferred to $100mm^2$ culture dishes coated with the extracelluar matrix. After 10 h of incubation, the media were replaced with media without fetal bovine serum and the concentration of insulin was lowered to 5 ng/ml. After 24 h, the media were changed to contain the varying concentrations of insulin and incubations continued for 48 h. The addition of insulin resulted in increases in the specific activity of ACC. The maximal effects of insulin on the ACC activity occurred at concentrations of insulin, 1,000 ng/ml. In contrast, the relative change in lactate dehydrogenase (LDH) activity in response to increasing insulin concentration was minimal as compared to the effects of insulin on ACC. Transblot and enhanced chemiluminescence (ECL) analysis indicated that the increase in ACC activity in MAC-T cells caused by insulin were due to actual increases in amounts of enzyme.

• 대한치과교정학회지
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• 제19권2호
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• pp.75-84
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• 1989

The purpose of this experiment was to measure the amounts of nickel and chromium released from a simulated orthodontic appliance in artificial saliva. Simulated mandibular half-arch orthodontic appliances were composed of American Iron and Steel Institute type 304 brackets, Permachrome, Elgiloy, Australian wire, T.M.A. and Nitinol. The amounts of nickel and chromium released from sample were measured with atomic absorption spectrophotometer after 3, 6, 9, 12, 15 days. The cumulative amounts of nickel released from Permachrome, Elgiloy, Australian wire and T.M.A. reached a plateau after 6 days. But the cumulative amounts of nickel released from Nitinol increased continuously. Significant amounts of both nickel and chromium were solubilized from the simulated orthodontic appliances into artificial saliva. After 15 days, total cumulative amounts of nickel were $152.15{\mu}g$, $150.27{\mu}g$, $134.74{\mu}g$, $114.67{\mu}g$ and $93.39{\mu}$ from the Elgiloy, Australian wire, Nitinol, Permachrome and T.M.A., respectively. Total cumulative amounts of chromium from Permachrome, Australian wire, Elgiloy, Nitinol and T.M.A. were $100.83{\mu}g$, $83.64{\mu}g$, $81.61{\mu}g$, $14.90{\mu}g$ and $12.43{\mu}g$, respectively. The result showed that nickel released from Elgiloy and chromium released from Permachrome were more than any others.

• International Journal of Industrial Entomology and Biomaterials
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• 제8권2호
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• pp.129-133
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• 2004

The breeding work was initiated by utilizing two Japanese hybrids namely C135${\times}$N134 and N137${\times}$C146 along with two evolved Indian breeds, J14 and A24. The breed CSR16 which is characterized with marked larvae and white dumbbell cocoons was evolved from the Japanese hybrid C135${\times}$N134 by crossing with J14, while the breed CSR17 which is characterized with plain larvae and white oval cocoons was evolved from the Japanese hybrid N137${\times}$C146 by crossing with A24. The hybrid of these evolved breeds i.e., CSR16${\times}$CSR17 has shown superior over control hybrid $KA{\times}{NB_4}{D_2}$ and on par with the ruling hybrid of CSR2${\times}$CSR4. The hybrid CSR16${\times}$CSR17 was authorized during 1999 by Central Silk Board, Bangalore, Government of India for commercial exploitation during favourable months based on national level race authorization test.

• Natural Product Sciences
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• 제27권2호
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• pp.134-139
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• 2021

A new cipadesin limonoid, i.e. 3-epi-cipadonoid C (1), and a new tirucallane triterpene, i.e. hispidol B 3-palmitate (3), have been isolated from the seeds and fruit peels extract of Sandoricum koetjape, respectively. Along with these compounds the known limonoid, cipaferen G (2), and two pentacyclic triterpenes, bryonolic (4) and bryononic (5) acids, were also isolated. The strucrures of the new compounds were elucidated by the analysis of NMR and mass spectral data. Compounds 1 - 5 were evaluated as the inhibitor of receptor tyrosine kinases (EGFR, Epidermal Growth Factor Receptor; HER2, HER4, Human Epidermal growth factor Receptor 2, -4; IGFR, Insulin-like Growth Factor Receptor; InsR, Insulin Receptor; KDR, Kinase insert Domain Receptor; PDGFRα, and PDGFRβ, Platelet-Derived Growth Factor Receptor-α and -β). The results showed only 1 and 3 that have weak activity against InsR.

• 분석과학
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• 제23권6호
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• pp.544-550
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• 2010

담홍색 열매체유를 포도주로 오인하고 음용하여 사망한 변사사건에서 열매체유 중 39%의 에틸렌글리콜을 확인하였다. 열매체유는 물을 열전달 매체로 사용하였을 경우 고온에서 발생되는 고압 수증기에 의한 문제를 피하기 위하여 사용되는 열전달 매체로 주로 광유계 또는 에틸렌글리콜을 사용하는 것으로 알려져 있다. 부검을 통한 혈액 및 기타 조직 등의 변사자 생체시료에서 중수소로 치환된 에틸렌글리콜을 내부표준물질로 하여 아세토니트릴로 추출, 정제 및 질소 기류하에서 농축한 다음 1% TMCS가 함유된 BSTFA로 유도체화하여 에틸렌글리콜과 그 대사체인 글리콜산을 GC/MS에 의하여 동시 분석하였다. 약 0.2 g의 생체시료에 대하여 0.5 M의 HCl 용액 $50\;{\mu}L$를 이용한 산성조건에서 추출하였으며 무수 황산나트륨을 단계적으로 처리하여 수분제거를 하였고 혈액에서 $2,755\;{\mu}g/mL$의 에틸렌글리콜과 $174\;{\mu}g/mL$의 글리콜산 및 기타 시료에서 $860\;{\mu}g/g\sim1,290\;{\mu}g/g$의 에틸렌글리콜과 $93\;{\mu}g/g\sim134\;{\mu}g/g$의 글리콜산을 검출하였다. 특히 신장 조직에서 이와 관련된 대사체인 옥살산염으로 추정되는 결정이 관찰되었다.

• International Journal of Computer Science & Network Security
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• 제24권5호
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• pp.129-134
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• 2024

Object Detection is an emerging technology in the field of Computer Vision and Image Processing that deals with detecting objects of a particular class in digital images. It has considered being one of the complicated and challenging tasks in computer vision. Earlier several machine learning-based approaches like SIFT (Scale-invariant feature transform) and HOG (Histogram of oriented gradients) are widely used to classify objects in an image. These approaches use the Support vector machine for classification. The biggest challenges with these approaches are that they are computationally intensive for use in real-time applications, and these methods do not work well with massive datasets. To overcome these challenges, we implemented a Deep Learning based approach Convolutional Neural Network (CNN) in this paper. The Proposed approach provides accurate results in detecting objects in an image by the area of object highlighted in a Bounding Box along with its accuracy.

• 한국결정성장학회지
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• 제22권3호
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• pp.134-138
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• 2012

Recently the preparation magnetic nanoparticles by a pulsed laser ablation in liquid has gained much attention because it is easy to control experimental parameters. Iron oxide magnetic nanoparticles have been prepared by a pulsed laser ablation of ${\alpha}-Fe_2O_3$ target in ethanol at different magnitude of laser energy of 1, 20, 40 and 80 mJ/pulse. It revealed that particle size increases with increasing laser energy. It could be concluded that 40 mJ/pulse is an optimum laser energy for the preparation of iron oxide nanoparticles with uniform size distribution. The nanoparticles are homogeneously dispersed in ethanol and their stability maintained for several months.

• Parasites, Hosts and Diseases
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• 제28권1호
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• pp.25-30
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• 1990

질트리코모나스(Trichomonas vaginalis)감염 환자 30명과 비감염 건강 대조군 30명을 패 상으로 혈청 내 항-질트리코모나스 IgG 및 IgM 항체가를 효소표식 면역검사법(enzyme-linked immunosorbent assay: ELISA)으로 측정하여 이 질환 진단법으로서 ELISA의 이용 가능성을 검토 하고, 현펑 내 IgG 및 IsM 항체가의 상관성을 알아보았다. 질트리코모나스 환자의 혈청 내 IgG 항체가는 0.37±0.134로 건강 대조군의 0.21±0.054 보다 유 의하게 높았다(p<0.005). 또 혈청 내 IgG 항체가 0.32 이상을 양성으로 하였을 때 ELISA 진단법 의 감수성은 70.0%이었고 특이성은 96.7%이었다. 질트리코모나스 환자의 혈청 내 IsM 항체가는 0.33±0.177로 건강 대조군의 0.11±0.051 보다 유의하게 높았다(p<0.005). 또 혈청 내 Is변 항체 가 0.21 이상을 양성 반응으로 하였을 때 감수성은 70.0%이었고 특이성은 96.7%이었다. 질트리코 모나스 환자의 혈청 내 IgG 와 IsM 항체가의 상관 관계는 상관계수 r=0.77로 유의한 상관관계가 인 정 되 었 다(p<0.005). 이상의 결과로 보아 질트리코모나스 환자에서 혈청 내 19G 및 IsM 항체가를 ELISA법으로 측정 함으로써 질트리코모나스 감염을 진단하거나 역학적 조사에 이용할 수 있을 것으로 생각된다.