• The KIPS Transactions:PartD
• /
• v.18D no.1
• /
• pp.57-66
• /
• 2011

Recently, the necessity of new methods of spatial data integration and analysis in CRM has been increased since it is acknowledged that about eighty percent of all data stored in corporate databases has a spatial component. But conventional CRM systems are either incapable of managing spatial data or are not user-friendly when doing so. This paper has designed and implemented spatially-enabled integration management system that can manage consistently both enterprise and spatial data through a legacy CRM system and object-oriented database and additionally support spatial analysis and map visualization for a gCRM. Through implementation, it is demonstrated that the proposed system can facilitate effectively spatial data management and analysis in a legacy CRM system.

• STI Policy Review
• /
• v.1 no.3
• /
• pp.1-15
• /
• 2010

This paper makes the case that a new policy strategy to enhance a global green recovery is needed urgently. The new strategy requires two essential elements. First, G20 economies should follow the lead of South Korea and China and turn their green stimulus investments into a serious long-term commitment, and to support these investments, they should adopt environmental pricing policies and instigate pricing and regulatory reforms to reduce carbon dependency. Second, the G20 also needs to target and coordinate assistance to developing economies in science, technology and innovation (STI) for clean energy. Such assistance is essential to help developing economies to overcome the skills, technological and capital gap that they face in clean energy technologies over the long term. Reform of the Clean Development Mechanism (CDM) is also necessary to establish a long-term global price signal for carbon, and to increase the coverage of developing economies, the sectors and technologies and the overall financing of clean energy projects. Formulating such a policy strategy should appeal to both the Asian-Pacific and Western economies comprising the G20, and by working together to formulate such a strategy, the G20 could lead the way toward a new era of global economic management and STI cooperation in clean energy.

• Parasites, Hosts and Diseases
• /
• v.61 no.4
• /
• pp.388-396
• /
• 2023

Entamoeba histolytica is an enteric tissue-invasive protozoan parasite causing amoebic colitis and liver abscesses in humans. Amoebic contact with host cells activates intracellular signaling pathways that lead to host cell death via generation of caspase-3, calpain, Ca²⁺ elevation, and reactive oxygen species (ROS). We previously reported that various NADPH oxidases (NOXs) are responsible for ROS-dependent death of various host cells induced by amoeba. In the present study, we investigated the specific NOX isoform involved in ROS-dependent death of hepatocytes induced by amoebas. Co-incubation of hepatoma HepG2 cells with live amoebic trophozoites resulted in remarkably increased DNA fragmentation compared to cells incubated with medium alone. HepG2 cells that adhered to amoebic trophozoites showed strong dichlorodihydrofluorescein diacetate (DCF-DA) fluorescence, suggesting intracellular ROS accumulation within host cells stimulated by amoebic trophozoites. Pretreatment of HepG2 cells with the general NOX inhibitor DPI or NOX2-specific inhibitor GSK 2795039 reduced Entamoeba-induced ROS generation. Similarly, Entamoeba-induced LDH release from HepG2 cells was effectively inhibited by pretreatment with DPI or GSK 2795039. In NOX2-silenced HepG2 cells, Entamoeba-induced LDH release was also significantly inhibited compared with controls. Taken together, the results support an important role of NOX2-derived ROS in hepatocyte death induced by E. histolytica.

• Journal of Internet Computing and Services
• /
• v.20 no.3
• /
• pp.129-135
• /
• 2019

Recently, it is anticipated that 5G network would play the significant role of the neural network for 4th generation industry revolution and create huge value for the new market. However, in spite of proliferating prospect of 5G network industry and leading position in the launch of 5G, network operators have hesitated to give their full support to establishing proper network. Due to the lack of business models promoting 5G industry, network operators feel that they will not realize the return from the exorbitant investment in 5G network establishment. Moreover, the rigorous research efforts to investigate and analyze the various business environments regarding 5G rarely exists. Therefore, the purpose of the research is to holistically propose the research issues related to the technology, service providing method, governmental policy, and business models in commercializing and promoting 5G network.

• Journal of the Korea Society of Computer and Information
• /
• v.27 no.10
• /
• pp.105-113
• /
• 2022

In this paper, we present and analyze 5G system and IEEE time-sensitive networking(TSN) and propose a novel mobility management scheme for time sensitive communications in 5G-TSN to support ultra-low latency networks. Time-sensitive networking(TSN) has a promising future in the Industrial Automation and Industrial Internet of Things(IIoT), as a key technology that is able to provide low-latency, high-reliable and deterministic communications over the Ethernet. When a TSN capable UE moves the TSN service coverage from the non-TSN service coverage, the UE cannot get the TSN service promptly because the related mobility management is not performed appropriately. For the mobility situation with the TSN service coverage, the proposed scheme reports TSN capability to the network and triggers the initial registration in order to be provided the TSN service immediately and ultra-low latency communications compared to existing schemes in 5G mobile networks.

• Journal of the Korean Society of Industry Convergence
• /
• v.26 no.2_2
• /
• pp.315-325
• /
• 2023

Recently, various dynamic risk analysis methods have been suggested for estimating the risk index by predicting the possibility of accidents and damage. It is necessary to maintain and support the safety system for responding to accidents by continuously updating the probability of accidents and the results of accidents, which are quantitative standards of ship risk. In this study, when a LNG leakage that may occur in the LN G Fuel Gas Supply System (FGSS) room during LN G bunkering operation, a reliability physical model was prepared by the change in monitoring data as physical parameters to estimate the accident probability. The scenario in which LNG leakage occur were configured with FT (Fault Tree), and the coefficient of the covariate model and Weibull distribution was estimated based on the monitoring data. The possibility of an LNG leakage, which is the top event of FT, was confirmed by changes in time and monitoring data. A method for estimating the LNG leakage based on the reliability physical analysis is proposed, which supports fast decision-making by identifying the potential LNG leakage at the accident.

• Korean Journal of Computational Design and Engineering
• /
• v.10 no.1
• /
• pp.1-10
• /
• 2005

This paper presents an embodiment of design integration framework corresponding to changes in the latest manufacturing environment. The embodied system is named by 'WEB-KBE System' because it supports a product design with a KBE technique based on web environment. The final purpose of the work is to implement a web-based integration design environment with a KBE technique to support non-skillful designers. The framework of the system Is designed to support necessary items in user-centric design environment. Two case studies were applied to the WEB-KBE system to evaluate the efficiency, flexibility, extensibility, and reusability of the system. The examples are [1] CART integration design environment construction and (2) Exhaust Duct Saddle Support integration design environment construction. In the former case, it took a period of 8 months for modeling and implementation of the WEB-KBE prototype system. However, with the high extensibility and reusability of WEB-KBE system, the second case required only a period of one month for modeling and implementation of the system. We conclude that the presented WEB-KBE system can bring fair effects on implementing a knowledge based design environment in aspect of time and expense.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.26 no.2
• /
• pp.101-114
• /
• 2024

Currently, in Korea, the number of handicapped children receiving inclusive education in general schools is expanding. In the inclusive education field, the most important tasks are personal needs support, such as toilet assistance, meal assitance, and support for wearing and taking off various assistive devices. A significant portion of the support work in the actual education field is related to clothing. Therefore, it is necessary to research and develop universal fashion designs for handicapped children at school where inclusive education is implemented. To achieve this aim, this study analyzed the concepts, principles and, characteristics of universal fashion design through theoretical research and established research principles. In this study, two fact-finding surveys were conducted. Next, a total of 10 universal fashion designs were proposed considering both the preceding survey results and the principles of universal fashion design Among them, the four designs that were considered most suitable were selected for universal fashion design through F.G.I (Focus Group Interview) analysis conducted by experts. The four selected designs were made by referring to the size framework based on the '6th Human Body Size Survey Report of Korea'. The completed experimental clothes were proposed as the final universal fashion design for handicapped children by conducting external evaluation through a virtual clothing system and real clothes.

• Journal of Applied Biological Chemistry
• /
• v.63 no.3
• /
• pp.197-201
• /
• 2020

In order to enhance the extraction efficiency of flavonoid from Saururus chinensis, carbohydrate-hydrolyzing enzyme Viscozyme L aided extraction techniques have been studied. Then flavonoid composition, as well as quercetin, were also identified using UV/Vis, HPLC/MS, and ¹H-NMR. The results showed that favorable extraction conditions were Viscozyme L concentration of 0.25 mg/g, pH 4.2, reaction at 45 ℃ for 12 h. Under the favorable extraction condition, total flavonoid yield (37.9 mg/g) and quercetin yield (0.86 mg/g) increased by about 2.0 and 9.6 times, respectively, compared to control group. Interestingly, as a significant flavonoid of S. chinensis, flavonoid glycones rutin was hydrolyzed to aglycones quercetin by Viscozyme L. These findings provide scientific and theoretical support for the development quercetin-rich products, which was quickly absorbed by the human body than rutin.

• Interaction and multiscale mechanics
• /
• v.3 no.1
• /
• pp.39-54
• /
• 2010

In this paper, a simple approach is presented for studying the dynamic response of multi-span steel bridges supported by pylons of different heights, subjected to earthquake motions acting along the axis of the bridge with spatial variations. The analysis is carried out using the modal analysis technique, while the solution of the integral-differential equations derived is obtained using the successive approximations technique. It was found that the height of piers and the quality of the foundation soil can affect significantly the dynamical behavior of the bridges studied. Illustrative examples are presented to highlight the points of concern and useful conclusions are gathered.