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Anti-cancer and Anti-inflammatory Effects of Mung Bean and Soybean Extracts (녹두 및 대두추출물의 항암 및 항염증 활성)

  • Imm, Jee-Young;Kim, Seok-Joong
    • Korean Journal of Food Science and Technology
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    • v.42 no.6
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    • pp.755-761
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    • 2010
  • The quinone reductase (QR) inducing activities of mung bean and soybean solvent extracts were compared using murine hepatoma cells (Hepa 1c1c7). The mung bean extracts (ethylacetate and ethanol) showed higher chemoprevention index values (7.88-8.22) than those of soybean extracts (2.9-5.2) from four different cultivars. The mung bean extracts also had significantly higher inhibitory effects (47-62% at 100 ${\mu}g$/mL) than the soybean extracts (15-42% at 100 ${\mu}g$/mL) against the production of nitric oxide and prostaglandin E2 in lipopolysccharide stimulated macrophage RAW264.7 cells without cytotoxicity. Among seven recovered fractions of mung bean ethanol extract obtained by C 18 silica flash column chromatography, the most non-polar fraction exhibited the highest chemoprevention index of 10.4.

Ginsenoside Contents and Hypocholesterolemic Effects of a By-Product in Ginseng Radix (인삼부산물 추출액의 ginsenosides 함량 및 고지방 식이에 있어 혈청 콜레스테롤 농도 개선에 미치는 효과)

  • Sihn, Eon-Hwan;Park, Sung-Jin;Han, Jong-Hyun;Park, Sung-Hye
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.2
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    • pp.459-465
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    • 2005
  • This study was conducted to investigate the application possibility of leaf and stem extract(LSE) extracted from mixture of leaf and stem of ginseng radix (Panax Ginseng C.A. Meyer). We conducted analysis of the ginsenoside content by HPLC. Also we investigate the effects of the LSE on the reduction of serum lipid and improvement of blood parameters in rats fed high fat diet 5 weeks. We examined by analyzing the serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride and atherogenic index and hematological datas and serum metabolic variables. Sprague-Dawley rat weigh $150\;g\;{\pm}\;15\;g$, were ramdomly assigned to 4 groups, basal diet only(BDG), high fat diet weithout LSE(FDCG), high fat diet and 10% LSE(FD10G), high fat diet and 20% LSE(FD20G). The result of this study were as follow. Hematological datas of 4 groups were same level, which were not significant. The activities of ALP, GOT and LDH level were significantly different. Total cholesterol, LDL-cholesterol, triglyceride contentrations in serum and atherogenic index were remarkably reduced in LSE supplemented groups as compared high fat control groups. These result imply that LSE could be used as possible for decrease of serum lipid concentration.

Maturation and Spawning of the Common Octopus Octopus vulgaris in the Coastal Waters of Yeosu, Korea (여수 연안에 출현하는 참문어(Octopus vulgaris)의 성숙과 산란)

  • Yang, Hye-Jin;Jin, Suyeon;Kim, Do-Gyun;Kim, Heeyong;Moon, Seong Yong;Baeck, Gun Wook
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.6
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    • pp.1000-1006
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    • 2021
  • The maturity and spawning of the common octopus Octopus vulgaris were studied using 317 samples collected monthly from January to December of 2020 from the coastal waters of Yeosu, Korea. The mantle length (ML) of O. vulgaris ranged from 5.1 to 19.7 cm and body weight (BW) ranged from 117.6 to 3,645.4 g. We analyzed monthly changes in sex ratio, gonadosomatic index (GSI), histological maturity stage, and body weight at 50%, 75% and 97.5% group maturity. The sex ratio was 1:1.02, which was not significantly different from the value that expected. Based on histological observation of the gonad development and gonadosomatic index, the spawning periods lasted throughout the year, with peak spawning periods estimated from March to April and July to August. The percentages of sexually mature females estimated using a logistic equation were over 50% at 554.46 g BW, 75% at 1,134.38 g BW and 97.5% at 2,474.22 g BW respectively.

Change in Spatial Dispersion of Daphnia magna(Cladocera: Daphniidae) Populations Exposed to Organophosphorus Insecticide, Diazinon (유기인계 살충제 (다이아지논)에 대한 물벼룩, Daphnia magna (Cladocera: Daphniidae) 개체군의 공간분산 변이)

  • Lee, Sang-Hee;Ji, Chang-Woo;Chon, Tae-Soo
    • Environmental Analysis Health and Toxicology
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    • v.24 no.3
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    • pp.231-240
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    • 2009
  • We explored collective behaviors of indicator species to elucidate the effect of the chemical stress. After the treatments of an insecticide, diazinon, at low concentrations (1.0 and 10.0 ${\mu}g/L$), spatial dispersion patterns of Daphnia magna were checked in a test chamber. The I-index was used to characterize the movement data before (0~1 h) and after (1~2 h) the treatments in laboratory conditions. The slopes of the frequency distribution of I-index in semi-log scale decreased significantly, and the test populations appeared to be more dispersed with a lower degree of aggregation after the treatments. The index was feasible in indicating decrease in the ability of the specimens to keep desirable distances with neighbor individuals under chemical stress and showed a possibility of monitoring presence of toxic chemicals in environment through group behavior measurement.

Characteristic of Growth and Active Ingredient in Angelica gigas Nakai according to Forest Environment by Climate Zone (기후대별 산림환경에 따른 참당귀의 생육 및 지표성분 특성)

  • Kim, Nam Su;Jeon, Kwon Seok;Lee, Hyun Seok
    • Korean Journal of Medicinal Crop Science
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    • v.28 no.3
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    • pp.221-228
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    • 2020
  • Background: Angelica gigas Nakai, that belong to the Umbelliferae family, is one of the traditional medicinal plants in Korea. Its roots have been used to treat gynecological diseases. In this study, growth characteristics and index components were compared with the forest microclimate at several forest sites. Methods and Results: A. gigas was planted in three climatic zones according to the temperature (southern temperature zone - Hamyang, central temperature zone - Bonghwa, and northern temperature zone - Jeongseon) and growth characteristics were investigated in comparison with the forest microclimate. Our results indicated that the root diameter and length, and fresh and dry weight were the highest in Jeongseon. The total content of decursin was the highest in Jeongseon (9.52%), followed by those in Hamyang (8.07%) and Bonghwa (7.48%), respectively. Additionally, the yield of decursin (1.39 g) was the highest in Jeongseon. Conclusions: The yield and index components were influenced by the microclimate in the forests, and it was assumed that high altitude and low temperature affected the increase in growth and index components. These results will be useful as basic data to study the correlation among environmental conditions, growth, and index components.

The Effect of Stepbox Exercise Program on Both Male and Female Elderly's Cardiovascular and Physiological Index (스텝박스 운동프로그램이 노년기 남녀의 심혈관 및 생리적 지수에 미치는 영향)

  • Yu, Gyoung-Won;Min, Soon;Ha, Yun-Ju
    • Journal of Korean Biological Nursing Science
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    • v.13 no.3
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    • pp.291-297
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    • 2011
  • Purpose: The research was to investigate the effect of stepbox exercise program on both male and female elderly' physiological index such as cardiovascular and to improve exercise efficacy. Methods: The research design was a non-equivalent control group, quasiexperimental study. From 2011-05-10 to 2011-07-26, 3 times a week for 12 weeks, the 43 elderly of health center of D district in G city who participated in the program and pre and post test at the same time were investigated. Results: Statistical significant differences had not been detected in systolic blood pressure and diastolic blood pressure, pulse showed a statistical significant differences. After test of physiological index, weights of participants showed decreasing tendency. body fat mass, skeletal muscle mass, BMI, body fat rate and waist-hip-ratio had also showed statistically significant differences. Conclusion: In conclusion, stepbox exercise program has positive effects on physiological index, blood pressure and pulse. Therefore, dynamic stepbox exercise program is considered to be a helpful intervention to improve comprehensive health conditions by giving the elderly both easy and less-pain exercise and the opportunity to manage their own health.

Proposal of Practical Reference-Model and It's Performance Improvement for PID Control (PID제어를 위한 실용적인 기준 모델 제안과 성능개선)

  • Hur, J.G.;Yang, K.U.
    • Journal of Power System Engineering
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    • v.11 no.3
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    • pp.66-72
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    • 2007
  • This study proposed new method to decide the reference model necessary for design PID controller. In generally, control design problems using the reference model have the following two factors. One factor is that numerical model of the controlled system can be obtained extremely, and the other is that specification for the closed-loop dynamic performance is pure moderate. Therefore, the control design procedure is essentially based on the partial reference model matching which offers a reasonable method to simplify the design and the controller configuration under the controlled system uncertainty. ITAE(Integral of time-multiplied absolute error) performance index and Kitamori method etc. which were used a reference model method had a limit to settling time and rising time of reference model that it arrived to steady state response according to the controlled system. On this study, if it only knew peak time of overshoot and settling time by measurement signal of the controlled system, it can be made the reference model easily. We proposed new method to improve performance index of the reference model superior to existing reference model index and illustrate the numerical simulation results to show the effectiveness of proposed control method design.

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Lack of Correlations among Histopathological Parameters, Ki-67 Proliferation Index and Prognosis in Pheochromocytoma Patients

  • Ocal, Irfan;Avci, Arzu;Cakalagaoglu, Fulya;Can, Huseyin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.4
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    • pp.1751-1755
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    • 2014
  • Background: In this study prognostic correlations of histopathologic parameters and the Ki-67 proliferation index and as well as the diagnostic value of immunohistochemical markers in pheochromocytomas were evaluated. Materials and Methods: A total of 22 patients diagnosed with a pheochromocytoma between 2000-2010 in Izmir Katip Celebi University Ataturk Training and Research Hospital were included. Diagnostic value of the PASS scoring system, and prognostic correlations of histopathologic parameters and Ki-67 proliferation index were investigated. SPSS for Windows 17.0 software was used for statistical analysis. Results: There was no statistically significant correlation between recurrence and clinicopathologic parameters or the PASS score (PASS>4). In addition, there were no statistically significant correlations between PASS score and clinicopathologic parameters, such as diameter (5 cm), weight (>100g), gender (female/male ratio) and age (25-45/45-55/>55). Besides, there were no significant correlation between diameter and clinicopathological parameters and also recurrence. However, there was a statistically significant correlation between Ki-67 proliferation index and capsule invasion (p=0.047). Conclusions: Some but not most of the findings in our study were concordant with the literature. To clarify relationships, investigations with standard scoring systems which are not affected by subjective factors and feature appropriate histopathological criteria should be made on larger study groups.

Enantioselective Membranes Based on Chitosan for The Separation of D- And L-Tryptophan

  • Jonggeon Jegal;Kim, Jang-Hoon;Kim, Jee-Hye;Lee, Kew-Ho;Lee, Yongtaek
    • Korean Membrane Journal
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    • v.5 no.1
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    • pp.25-30
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    • 2003
  • Chitosan membranes crosslinked with glutaraldehayde that contained chiral environment were prepared. The chitosan membranes were characterized using FTIR and swelling index measurements. Their swelling index in water ranged from 100 to 70%, depending on the crosslinking time. The separation of D- and L-isomers of tryptophan was achieved through a pressure driven membrane separation process, using the self-supporting crosslinked chitosan membranes. The chiral separation performance of the membranes depended strongly on the swelling index of the membranes and the separation conditions such as concentration of feed solutions and different operating pressures. Especially when a chitosan membrane with a swelling index of 70% was used, almost complete optical resolution of D- and L-tryptophan was obtained ; enantiomeric excess (ee %) of 97.92% and flux of 2.26 g/㎡$.$h.

Seismic vulnerability assessment of low-rise irregular reinforced concrete structures using cumulative damage index

  • Shojaei, Fahimeh;Behnam, Behrouz
    • Advances in concrete construction
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    • v.5 no.4
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    • pp.407-422
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    • 2017
  • Evaluating seismic performance of urban structures for future earthquakes is one of the key prerequisites of rehabilitation programs. Irregular structures, as a specific case, are more susceptible to sustain earthquake damage than regular structures. The study here is to identify damage states of vertically irregular structures using the well-recognized Park-Ang damage index. For doing this, a regular 3-story reinforced concrete (RC) structure is first designed based on ACI-318 code, and a peak ground acceleration (PGA) of 0.3 g. Some known vertical irregularities such as setback, short column and soft story are then applied to the regular structure. All the four structures are subjected to seven different earthquakes accelerations and different amplitudes which are then analyzed using nonlinear dynamic procedure. The damage indices of the structures are then accounted for using the pointed out damage index. The results show that the structure with soft story irregularity sustains more damage in all the earthquake records than the other structures. The least damage belongs the regular structure showing that different earthquake with different accelerations and amplitudes have no significant effect on the regular structures.