• 한국의류산업학회지
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• 제20권5호
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• pp.616-620
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• 2018

Recently, many researches have been conducted to improve the performance and wearability of smart wearables. In this study, we designed and fabricated the signal and power transmission textile cables for smart wearables which have excellent wearability, durability and reliability. For the signal transmission textile cables, conductive yarns for the signal line and the ground line were developed. Three types of signal transmission textile cables have been developed using the conductive yarns. Linear density, tensile properties, electrical resistance and RF characteristics were tested to characterize the physical and electrical properties of three signal transmission textile cables. The conductive yarns have the very low resistance of $0.05{\Omega}/cm$ and showed excellent uniformity of electric resistance. Therefore, the electrical resistance of the signal transmission fiber cable can be reduced by increasing the number of conductive yarns used in signal and ground lines. However, the radio frequency (RF) characteristics of the signal transmission textile cables were better as the number of strands of the conductive yarns used was smaller. This is because the smaller the number of strands of conductive yarn used in signal transmission textile cables, the narrower and more parallel the distance between the signal line and the ground line. It is expected that the signal and power transmission textile cable for signal and power transmission will be utilized in smart wearable products.

• Journal of Korean Neurosurgical Society
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• 제51권1호
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• pp.31-36
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• 2012

Objective : The purpose of this study was to elucidate the anatomical development of physiologic suture closure processes in infants using three dimensional reconstructed computed tomography (CT). Methods : A consecutive series of 243 infants under 12 months of age who underwent three dimensional CT were included in this study. Four major cranial sutures (sagittal, coronal, lambdoidal and metopic suture) were classified into four suture closure grades (grade 0=no closure along the whole length, grade 1=partial or intermittent closure, grade 2=complete closure with visible suture line, grade 3=complete fusion (ossification) without visible suture line), and measured for its closure degree (suture closure rates; defined as percentage of the length of closed suture line divided by the total length of suture line). Results : Suture closure grade under 12 months of age comprised of grade 0 (n=195, 80.2%), grade 1 (n=24, 9.9%) and grade 2 (n=24, 9.9%) in sagittal sutures, whereas in metopic sutures they were grade 0 (n=61, 25.1%), grade 1 (n=167, 68.7%), grade 2 (n=6, 24%) and grade 3 (n=9, 3.7%). Mean suture closure rates under 12 months of age was 58.8% in metopic sutures, followed by coronal (right : 43.8%, left : 41.1%), lambdoidal (right : 27.2%, left : 25.6%) and sagittal sutures (15.6%), respectively. Conclusion : These quantitative descriptions of cranial suture closure may help understand the process involved in the cranial development of Korean infants.

• 한국의류학회지
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• 제38권5호
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• pp.675-689
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• 2014

This study developed an ideal jeggings pattern with an improved body fit for 20-24 year old females. The results of the study are as follows. First, samples for wearing test were made using jegging patterns from three manufacturers; subsequently, one pattern with a relatively outstanding body fit was selected from the first test. The selected pattern suggested a tight knee, belly, and crotch, high front waist line, and low back waist line. The side lines were also lean to the front; consequently, the front hip width was extended for 0.5cm for more space around the belly and the extended front knee part for 0.2cm to increase moving suitability to fix the leaning side lines. A 1cm front waist line was extended for 0.5cm to fix it lower; in addition, the back waist line 3.0cm was extended for 0.5cm to heighten it. The crotch width was also extended for 0.5cm to add more space. The second wearing test for the fixed forms were evaluated for their outstanding features in appearance as well as moving functions that were proposed as final jeggings forms. The results of the study suggested a jeggings pattern with a better body fit using manufacturer patterns that can be used as basic data for pant patterns with better fitting using various stretch fabrics.

• Journal of Gastric Cancer
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• 제23권1호
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• pp.224-249
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• 2023

Gastric cancer is heterogeneous in morphology, biology, genomics, and treatment response. Alterations in human epidermal growth factor receptor 2 (HER2) overexpression, microsatellite instability (MSI) status, programmed death-ligand 1 (PD-L1) levels, and fibroblast growth factor receptor 2 (FGFR2) can be used as biomarkers. Since the combination of fluoropyrimidine/platinum plus trastuzumab that was investigated in the ToGA trial was approved as a standard of care in HER2-positive patients in 2010, no other agents showed efficacy in the first- (HELOISE, LOGiC, JACOB trials) and second- (TyTAN, GATSBY, T-ACT trials) line treatments. Despite the success in treating breast cancer, various anti-HER2 agents, including a monoclonal antibody (pertuzumab), an antibody-drug conjugate (ADC; trastuzumab emtansine [T-DM1]), and a small molecule (lapatinib) failed to translate into clinical benefits until the KEYNOTE-811 (first-line) and DESTINY-Gastri01 (≥second-line) trials were conducted. The incorporation of HER2-directed treatment with immune checkpoint inhibitors in the form of a monoclonal antibody or ADC is now approved as a standard treatment. Despite the promising results of new agents (engineered monoclonal antibodies, bi-specific antibodies, fusion proteins, and small molecules) in the early phase of development, the management of HER2-positive gastric cancer requires further optimization to achieve precision medicine with a chemotherapeutic backbone. Treatment resistance is a complex process that can be overcome using a combination of chemotherapy, targeted agents, and immune checkpoint inhibitors, including novel agents. HER2 status must be reassessed in patients undergoing anti-HER2 treatment with disease progression after the first-line treatment. As a general guideline, patients who need systemic treatment should receive chemotherapy plus targeted agents, anti-angiogenic agents, immune checkpoint inhibitors, or their combinations.

• Journal of Plant Biotechnology
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• 제34권4호
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• pp.323-329
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• 2007

토마토 형질전환체에서 NPTII 및 TPSP 유전자의 발현양상을 조사하였다. 4개 line 토마토 형질전환체가 선발배지에서 kanamycin에 저항성을 보이며 생산되었다. 그러나, 1번 line과 11번 line의 후대에서 NPTII 유전자의 발현이 억제되었으며, Kanamycin 저항성을 보이지 못했다. Southern 분석 결과, 1번 11번 line은 여러 copy의 외래 유전자를 가지고 있었으며, 2번, 10번 line은 1-2 copy의 외래유전자를 가지고 있었다. 형질전환 line 11번은 methylation sensitive 제한효소처리 후 DNA methylation 분석 결과, TPSP coding부위 및 도입유전자의 발현을 조절하는 CaMV35S 프로모터 주위에서 CpG methylation이 축적되었음이 확인되었다. 따라서 여러 copy의 외래유전자를 가진 토마토 형질전환 line 11번에서 NPTII 유전자 및 TPSP유전자의 발현이 억제된 것은 transcriptional gene silencing 기작에 의한 것으로 추정되었다.

• 디자인학연구
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• 제14권4호
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• pp.65-75
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• 2001

주방 디자인의 패션화와 동서양 문화의 퓨전적 현상은 식기의 다양화와 세분화를 요구하고 있으며, 식사는 단지 먹는다는 의미보다 무엇을, 어디에, 어떻게 먹느냐의 문제로 발전되게 되었다. 이러한 문제는 자연이 현대의 식생활과 라이프 스타일에 부응하는 합리적이고 미적인 식기 개발을 요구하게 되었다. 이에 본 연구에서는 전통과 현대의 조화로운 만남, 젊은 감성과 품격을 동시에 충족시켜 줄 수 있는 미래형 식기 및 테이블 클로스 디자인을 연구하여 개발하는데 그 목적을 두었다. 연구의 방향은 식탁문화의 패션화와 퓨전적 현상에 따른 식기 사용의 세분화, 전문화, 다양화 욕구를 효율적으로 만족시키고자 고정된 세트 개념이 아닌 끝없이 연속되는 열린 코디네이션 개념을 식기에 도입하고, 색채 역시 믹스 앤 매치 방식의 칼라 코디네이션으로 다양한 식탁 표현을 연출 할 수 있는 새로운 식기 디자인을 통하여, 보수적인 우일요 이미지를 전통과 현대의 조화로운 젊은 감성과 감각의 이미지로 개선하였다. 연구의 디자인 개발 대상은 런치 웨어로 식기류 15품목 15종, 테이블 클로스 3품목 4종 등 총 19종과 디너 웨어로 식기류 8 품목 8종과 테이블 클로스 1품목 1종 등 총 9종으로 하였다. 연구결과 S/S 런치 웨어 세트로 테이블 웨어 디자인 15품목과 테이블 클로스 3품목이 개발되었으며, F/W 디너 웨어 세트로는 5종이 개발되었다.

• 한국발생생물학회지:발생과생식
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• 제15권3호
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• pp.239-247
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• 2011

Spermatogenesis and taxonomic values of mature sperm morphology of in male Septifer (Mytilisepta) virgatus were investigated by transmission electron microscope observations. The morphologies of the sperm nucleus and the acrosome of this species are the cylinder shape and cone shape, respectively. Spermatozoa are approximately 45-50 ${\mu}m$ in length including a sperm nucleus (about 1.26 ${\mu}m$ long), an acrosome (about 0.99 ${\mu}m$ long), and tail flagellum (about 45-47 ${\mu}m$). Several electron-dense proacrosomal vesicles become later the definitive acrosomal vesicle by the fusion of several Golgi-derived vesicles. The acrosome of this species has two regions of differing electron density: there is a thin, outer electron-dense opaque region (part) at the anterior end, behind which is a thicker, more electron-lucent region (part). In genus Septifer in Mytilidae, an axial rod does not find and also a mid-central line hole does not appear in the sperm nucleus. However, in genus Mytilus in Mytilidae, in subclass Pteriomorphia, an axial rod and a mid-central line hole appeared in the sperm nucleus. These morphological differences of the acrosome and sperm nucleus between the genuses Septifer and Mytilus can be used for phylogenetic and taxonomic analyses as a taxonomic key or a significant tool. The number of mitochondria in the midpiece of the sperm of this species are five, as seen in subclass Pteriomorphia.

• 한국어병학회지
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• 제24권2호
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• pp.47-51
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• 2011

The present study demonstrated lymphocystis disease virus (LCDV) propagation through cytopathic effects (CPE) formation and LCDV detection in olive flounder fin (FFN) cells by polymerase chain reaction (PCR) and fluorescent antibody technique (FAT) methods. Tissue filtrates from the cluster cells produced CPE in FFN cells, which initially cells became enlarged and gradually underwent fusion en masse. Infectivity of culture grown LCDV using the FFN cells reached $10^{2.3}$ $TCID_{50}$/ml at 4 days post infection and the highest titer was measured $10^{6.5}$ $TCID_{50}$/ml at 12 days. The viral DNA was detected in the cell culture supernatants showing CPE and the CPE cells by PCR. Antigen specific strong fluorescence reacting with monoclonal antibody against the virus revealed the presence of viral antigen in the cytoplasm of infected FFN cells. These results suggest that the FFN cell line originated from the olive flounder has a susceptibility of the LCDV.

• 한국산업융합학회 논문집
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• 제8권2호
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• pp.69-76
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• 2005

This study for Customer Satisfaction(Customer Focus) by Profit security' in the field Process improvement activity and man-power upgrade by DAS(DATA Acquisition System) in the Plant that is fusion Off Line and On Line(IT), Especially the basic of the most foundation in the beginning Step of Toyota system is 3-jeong(a standard instrument; right volume, right box, right position), 5S(Seiri, Seiton, Seisoh, Seiketsu, Sitsuke ; KAISEN, KANBNA System(for Logistic), Further more KPC has established the digital environment such as CIM ; Computer Integrated Manufacturing), IMS ; Intelligent Manufacturing System ERP ; Enterprise Resource Planning, DAS; Data Acquisition System, Autonomous QC & SPC etc,.) in order to realize the intelligent informatization, which is core base for obtaining the competitive power and for responding to the various 21C management environment in flexibility. In this digital management environment, continuously and powerfully they would advance for becoming the best of the world. For strategic changes to take place in industry 3 key important factors need to be included ; Integration of tasks function and process, Decentralization of information, Responsibility, Finally simplification of products and product structures.

• 대한기계학회논문집
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• 제10권5호
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• pp.625-634
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• 1986

본 연구에서는 알루미늄 합금인 알루미늄 2014와 6061의 이재를 V형 맞대기 이음을 한 후 정적인장하중을 가하여 모아레법에 광탄성 피복법을 조합한 방법에 의 해 변형율을 실시간(real time)에서 측정하고 유한요소법으로 해석한 결과와 비교검 토하였다.