• Journal of the Korean Vacuum Society
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• v.15 no.5
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• pp.465-474
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• 2006

A gas fueling system composed of a gas reservoir, an on-off valve, and a gas transferring tube, which is the simplest construction for the pre-programmed gas puffing, was simulated by numerically solving the time-dependent one-dimensional gas flow equation. The purpose of the simulation is to establish the relationship between the gas flow pattern (the elapsed time to the maximum flow, the maximum flow rate, the gas pulse duration) and the system parameters (the filling pressure and the volume of the gas reservoir, and the length and the diameter of the gas transferring tube).

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.11b
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• pp.3-6
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• 2001

In common globular proteins, the native form is in its most stable state. However, the native form of inhibitory serpins (serine protease inhibitors) and some viral membrane fusion proteins is in a metastable state. Metastability in these proteins is critical to their biological functions. Our previous studies revealed that unusual interactions, such as side-chain overpacking, buried polar groups, surface hydrophobic pockets, and internal cavities are the structural basis of the native metastability. To understand the mechanism by which these structural defects regulate protein functions, cavity-filling mutations of a 1-antitrypsin, a prototype serpin, were characterized. Increasing conformational stability is correlated with decreasing inhibitory activity. Moreover, the activity loss appears to correlate with the decrease in the rate of the conformational switch during complex formation with a target protease. We also increased the stability of a 1-antitrypsin greatly via combining various stabilizing single amino acid substitutions that were distributed throughout the molecule. The results showed that a substantial increase of stability, over 13 kcal/mol, affected the inhibitory activity with a correlation of 11% activity loss per kcal/mol. The results strongly suggest that the native metastability of proteins is indeed a structural design that regulates protein functions and that the native strain of a 1-antitrypsin distributed throughout the molecule regulates the inhibitory function in a concerted manner.

• Electrical & Electronic Materials
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• v.14 no.12
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• pp.3-6
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• 2001

In common globular proteins, the native form is n its most stable state. However, the native form of inhibitory serpins (serine protease inhibitors) and some viral membrane fusion proteins is in a metastable state. Metastability in these proteins is critical to their biological functions. Our previous studies revealed that unusual interactions, such as side-chain overpacking, buried polar groups, surface hydrophobic pockets, ad internal cavities are the structural basis of the native metastability. To understand the mechanism by which these structural defects regulate protein functions, cavity-filling mutations of $\alpha$1-antitrypsin, a prototype serpin, were characterized. Increasing conformational stability is correlated with decreasing inhibitory activity. Moreover, the activity loss appears to correlate with the decrease in the rate of the conformational switch during complex formation with a target protease. We also increased the stability of $\alpha$1-antitrypsin greatly via combining various stabilizing single amino acid substitutions that were distributed throughout the molecule. The results showed that a substantial increase of stability, over 13 kcal/mol, affected the inhibitory activity with a correlation of 11% activity loss per kcal/mol. The results strongly suggest that the native metastability of proteins is indeed a structural design that regulates protein functions and that the native strain of $\alpha$1-antitrypsin distributed throughout the molecule regulates the inhibitory function in a concerted manner.

• Nuclear Engineering and Technology
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• v.20 no.4
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• pp.246-252
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• 1988

Experiments on the hydrogen gas breakdown for plasma initiation in the KAERIT tokamak are described. The influence of the applied loop voltage, toroidal magnetic field, gas filling pressure, error magnetic field, and preionization is studied. It is concluded that the magnitude of the error field is the most important factor for successful discharge initiation. The gas breakdown voltage becomes minumum when the external compensating field most effectively corrects the net error field. Even though preionization effect is not prominent, it is exhibited more easily in the case of worse confinement. Discharge initiation conditions experimentally determined are compared with those calcuated from a theoretical model. Some other unknown physical processes maintain the operation range somewhat narrower than predicted by the present theoretical model. However, this model is adequate for the breakdown phase of tokamaks.

• Elastomers and Composites
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• v.55 no.2
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• pp.120-127
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• 2020

In this study, molding shrinkage of PPS resin was investigated. Two types of PPS resins with differing glass fiber and calcium carbonate content were used for this purpose. To observe mold shrinkage, molding conditions based on injection temperature, injection speed, and the position of the cushion were selected. Circular and rectangular specimens were used for the study model. Injection molding simulation was performed to predict the filling pattern and mold shrinkage, and the simulation results were compared with the experimental conclusions. It was observed that the mold shrinkage showed the highest shrinkage (distributed from 0.05% to 0.32%) dependence on the injection temperature, and the lowest shrinkage (distributed from 0.05% to 0.31%) dependence on the injection speed. The role of the position of the cushion in mold shrinkage was difficult to observe. The results of the simulation mostly agreed with the experimental results; however, for some molding conditions, the mold shrinkage in the simulation was overestimated as compared to that in the experiment.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.11a
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• pp.3-6
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• 2001

In common globular proteins, the native form is in its most stable state. However, the native form of inhibitory serpins (serine protease inhibitors) and some viral membrane fusion proteins is in a metastable state. Metastability in these Proteins is critical to their biological functions. Our previous studies revealed that unusual interactions, such as side-chain overpacking, buried polar groups, surface hydrophobic pockets, and internal cavities are the structural basis of the native metastability. To understand the mechanism by which these structural defects regulate protein functions, cavity-filling mutations of ${\alpha}$1-antitrypsin, a prototype serpin, were characterized. Increasing conformational stability is correlated with decreasing inhibitory activity. Moreover, the activity loss appears to correlate with the decrease in the rate of the conformational switch during complex formation with a target protease. We also increased the stability of ${\alpha}$1-antitrypsin greatly via combining various stabilizing single amino acid substitutions that were distributed throughout the molecule. The results showed that a substantial increase of stability, over 13 kcal/mol, affected the inhibitory activity with a correlation of 11% activity loss per kcal/mol. The results strongly suggest that the native metastability of proteins is indeed a structural design that regulates protein functions and that the native strain of e 1-antitrypsin distributed throughout the molecule regulates the inhibitory function in a concerted manner.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.48 no.6
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• pp.8-17
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• 2011

Recently, fusion camera systems that consist of depth sensors and color cameras have been widely developed with the advent of a new type of sensor, time-of-flight (TOF) depth sensor. The physical limitation of depth sensors usually generates low resolution images compared to corresponding color images. Therefore, the pre-processing module, such as camera calibration, three dimensional warping, and hole filling, is necessary to generate the high resolution depth map that is placed in the image plane of the color image. However, the result of the pre-processing step is usually inaccurate due to errors from the camera calibration and the depth measurement. Therefore, in this paper, we present a depth map upsampling method robust these errors. First, the confidence of the measured depth value is estimated by the interrelation between the color image and the pre-upsampled depth map. Then, the detailed depth map can be generated by the modified kernel regression method which exclude depth values having low confidence. Our proposed algorithm guarantees the high quality result in the presence of the camera calibration errors. Experimental comparison with other data fusion techniques shows the superiority of our proposed method.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.10
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• pp.1031-1041
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• 2009

A small microstrip monopole antenna for macro-micro frequency tuning over multiple bands is presented. The meander-shape antenna is fabricated on a conventional printed circuit board(FR-4, $\varepsilon_r=4.4$ and tan $\delta=0.02$). The antenna operates over WiBro(2.3~2.4 GHz) and WLAN a/b(2.4~2.5 GHz/5.15~5.35 GHz) service bands with an essentially constant antenna gain within each service band. Two diodes, a PIN diode and a varactor, are embedded into the antenna for frequency reconfiguration. The PIN diode is used for frequency switching(macro-tuning) between 2 GHz and 5 GHz bands while the varactor is used for frequency tuning(micro-tuning) within the service bands, 2.3~2.5 GHz and 5.15~5.35 GHz. Unwanted resonances between the two frequency bands(2 GHz and 5 GHz) are suppressed by filling up the gaps between the meander lines. The antenna gain is essentially constant and higher than 2 dBi within each service band. The measured performance of the proposed antenna system suggests the macro-micro frequency tuning techniques be useful in reconfigurable wireless communication systems.

• Polymer(Korea)
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• v.35 no.5
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• pp.467-471
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• 2011

PET bottle is manufactured by blow molding the preform, which is molded by injection molding. The neck part of the preform of PET bottle for juice or grain-based beverage is crystallized before blowing to improve heat resistance at the entrance of the bottle. However, residual stress, developed during injection molding of preform, prevents the crystallization. In order to release the residual stress in the preform, the preform is annealed after the injection molding. If the residual stress is reduced by optimizing the injection molding conditions of preform the annealing time would be shortened. In this study, the optimum conditions for minimizing the residual stress and increasing dimensional accuracy of the injection molded preform are suggested through CAE analysis. In order to optimize the molding conditions, minimizing residual stress and shrinkage, computer simulations have been carried out with help of design of experiment scheduling. Injection temperature, initial packing pressure and filling time were selected for control parameters. Residual stress was affected by injection temperature and filling time. Shrinkage was affected by injection temperature. It was found that maximum residual stress, distribution of residual stress and shrinkage were decreased by 22%, 40% and 25%, respectively at an optimum molding condition compared with the results of previous molding condition.

• Journal of Korean Neurosurgical Society
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• v.30 no.sup2
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• pp.300-308
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• 2001

Objectives : Anterior cervical discectomy and interbody fusion has become a well-accepted surgical treatment of degenerative cervical diseases. Implatable cages have a stabilizing effect without plates and no need for autogenous bone graft. The authors evaluates the effect of implatable titanium cage(RABEA) on the clinical and radiological outcomes. Methods : 34 patients with symptomatic cervical degenerative diseases due to one level disc pathology were underwent anterior cervical discectomy and interbody fusion with titanium cages(RABEA) which were not filled with cancallous bone grafts from January 1999 to May 2001. Patients with osteoporosis and older than 65 years were not included. Among them, 15 patients could be followed-up for at least 1 year. The authors retrospectively reviewed the charts and radiographic data. Mean follow-up period was $1.3{\pm}0.2years$. Results : Clinical results according to the Odom's criteria was exellent and good in 14(93%) patients. One patient with fair result showed complete loss of the disc space height due to settlement of the cage. Preoperatively, the mean height of the disc space(${\pm}$standard deviation) was $3.42{\pm}1.10mm$(range 2.0-5.5mm), and at 1 day postoperatively it was $7.88{\pm}0.90mm$(range 6.50-9.0). The mean height of the disc space after 1 year was $6.50{\pm}1.38mm$(range 3.0-8.0). The restoration of the height was statistically significant(p<0.05). The mean height after 1 year was $82.7{\pm}15.9%$ of the height at 1 day postoperatively. Preoperatively the mean value of the cervical lodortic angle was $21.8{\pm}11.8^{\circ}$ and 1 year postopertively, it was $24.5{\pm}8.3^{\circ}$, which was statistically not significant. All patients showed no abnormal movements on flexion and extension lateral film after 6 months. Conclusion : Implantable titanium cages appear safe and effective in selected patients, and their use helps to avoid complications associated with bone graft harvest. Subsidence of the cage seems to be a potential risk factor for recurrence of the symptoms. For long-term results, a longer follow-up is required.