• 한국신재생에너지학회:학술대회논문집
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• 2011.11a
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• pp.114.1-114.1
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• 2011

Bioenergy production from lignocellulosic biomass and agriculture wastes have been attracted because of its sustainable and non-edible source. Especially, canola is considered as one of the best feedstock for renewable fuel production. Oil extracted canola and its agriculture residues are reuseable for bioethanol production. However, a pretreatment step is required before enzymatic hydrolysis to disrupt recalcitrant lignocellulosic matrix. To increase the sugar conversion, more efficient pretreatment process was necessary for removal of saccharification barriers such as lignin. Alkaline pretreatment makes the lignocellulose swollen through solvation and induces more porous structure for enzyme access. In our previous work, aqueous ammonia (1~20%) was utilized for alkaline reagent to increase the crystallinity of canola residues pretreatment. In this study, significant factors for efficient soaking in aqueous ammonia pretreatment on canola residues was optimized by using the response surface method (RSM). Based on the fundamental experiments, the real values of factors at the center (0) were determined as follows; $70^{\circ}C$ of temperature, 17.5% of ammonia concentration and 18 h of reaction time in the experiment design using central composition design (CCD). A statistical model predicted that the highest removal yield of lignin was 54% at the following optimized reaction conditions: $72.68^{\circ}C$ of temperature, 18.30% of ammonia concentration and 18.30 h of reaction time. Finally, maximum theoretical yields of soaking in aqueous ammonia pretreatment were 42.23% of glucose and 22.68% of xylose.

• Journal of Engineering Education Research
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• v.19 no.2
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• pp.45-52
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• 2016

The employment rate of a college has long been one of the most important elements in college survival strategies. Employment rates may not be key to colleges' survival in other countries, but they are fundamental to colleges in Korea as seen in the Korean government-led National Competency Standard (NCS), which has been underway since its introduction to colleges in Korea. Against this backdrop, if the engineering accreditation system can contribute to improving employment rate in this context, it can take root more quickly. The process conducive to improving employment rates can be classified as both direct and indirect methods. With dwindling school-age population having impacts on colleges and universities, the environment and the education directions of colleges have rapidly been shifting since the introduction of the NCS. Therefore, various survival strategies for colleges need to be developed. An indicator of employment rate of college graduates is among the most important things during this transition process. The Department of Mechanical Engineering at Koje College has consistently shown good records during the past 5 years by matching the accreditation schemes and employment strategies. The department will help put in place the engineering technology education accreditation system at the college through its various innovative and effective programs. To formulate a better employment strategy, it is needed to reflect and consolidate the engineering accreditation scheme into the existing employment policy of college. In short, this paper examines both the engineering accreditation scheme and the employment policy in ways that helps produce a coupling matrix structure. This study looks into the measures for improving employment rates by better adjusting the engineering education methods under the accreditation scheme.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.6
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• pp.162-168
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• 2017

Carbon nanotube(CNT) is one of the promising construction materials to produce concrete with high strength and durability by adding in the concrete mixtures from various researches. Also, its superior heat conductivity can be one of the options to develop self-heating concrete. In this research, the fundamental study was conducted to investigate mechanical properties and microstructures of cement pastes and mortars by strength tests and porosity measurement with several CNT additions, which were 0 wt%, 0.115 wt%, 0.23 wt% and 0.46 wt% of CNT-cement ratio. Compressive and flexural strength test were conducted at 3, 7 and 28 days, and pore characteristics were investigated by mercury intrusion porosimetry. SEM-EDS and Thermogravimetric analysis(TGA) were conducted to prove the hydration product types and CNT dispersion in the cement matrix. As a result, even though high amount of CNT additions were caused worse performance, mixtures with 0.115 wt% of CNTs developed the similar performance with plain mixture.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.275-275
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• 2013

Formation and characterization of self-assembled monolayers (SAMs) on various surfaces are the essential basis for many other applications, including molecular switches, biosensors, microfluidics, and fundamental studies in surfaces and interfaces. To improve the performance at these applications, it is a key to control the quantity of each molecule in various mixed SAMs on the surface. In this study, using mixed SAM of carbamate-based hydroquinone (HQ)-PhBr and11-mercaptoundecanol, the quantitative mass spectrometric method of mixed SAM was developed based on comparison study with XPS and FT-IR methods. In addition, our method was applied to another mixed SAM of biotinylated PEG alkane thiol and 11-mercaptoundecanol for verification purpose. Time-of-flight secondary mass spectrometry (ToF-SIMS) analysis was performed to identify and quantify each molecule of mixed SAM along with principal component analysis (PCA). Since there is no matrix effect in the X-ray photoelectron spectroscopy (XPS) and Fourier transform-infrared (FT-IR) techniques, we compared ToF-SIMS results with XPS and FT-IR results. Because PCA results from ToF-SIMS analysis are well matched with XPS and FT-IR results from both mixed SAMs, we are expecting that our method will be useful to identify and quantify each molecule in various mixed SAMs.

• Journal of the Korean institute of surface engineering
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• v.49 no.6
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• pp.555-559
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• 2016

A biodegradable nanofiber scaffolds using electrospining provide fibrous guidance cues for controlling cell fate that mimic the native extracellular matrix (ECM). It can create a pattern using conventional electrospining method, but has a difficulty to generate one or more pattern structures. Femtosecond(fs) laser ablation has much interested in patterning on biomaterials in order to distinguish the fundamental or systemic interaction between cell and material surface. The ablated materials with a short pulse duration using femtosecond laser that allows for precise removal of materials without transition of the inherent material properties. In this study, linear grooves and circular craters were fabricated on electrospun nanofiber scaffolds (poly-L-lactide(PLLA)) by femtosecond laser patterning processes. As parametric studies, pulse energy and beam spot size were varied to determine the effects of the laser pulse on groove size. We confirmed controlling pulse energy to $5{\mu}J-20{\mu}J$ and variation of lens maginfication of 2X, 5X, 10X, 20X created grooves of width to approximately $5{\mu}m-50{\mu}m$. Our results demonstrate that femtosecond laser processing is an effective means for flexibly structuring the surface of electrospun PLLA nanofibers.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.22 no.4
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• pp.307-314
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• 2009

The present paper briefly describes the space frame element and the fundamental strategies in computational elastic bifurcation theory of geometrically nonlinear, single load parameter conservative elastic spatial structures. A method for large deformation(rotation) analysis of space frame is based on an eulerian formulation, which takes into consideration the effects of large joint translations and rotations with finite deformation(rotation). The local member force-deformation relationships are based on the beam-column approach, and the change in member chord lengths caused by axial strain and flexural bowing are taken into account. and the derived geometric stiffness matrix is unsymmetric because of the fact that finite rotations are not commutative under addition. To detect the singular point such as bifurcation point, an iterative pin-pointing algorithm is proposed. And the path switching mode for bifurcation path is based on the non-negative eigen-value and it's corresponding eigen-vector. Some numerical examples for bifurcation analysis are carried out for a plane frame, plane circular arch and space dome structures are described.

• Transactions of the Korean Society of Automotive Engineers
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• v.2 no.6
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• pp.94-101
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• 1994

About vibration model of Six-degrees-of-freedom(DOF), in mass load, examined results for knowing dynamic interference and response variation is as follows; In case of putting mass load upon the object, experimented results on two-degrees-of-freedom of the translation-1 direction and the rotation-1 direction at open-loop-control system, about 0.19 arcsed in input of the translation-$0.1{\mu}m$ and $0.022{\mu}m$ on input of the rotation-0.5 arcsec, the justicse of motion equation is acknowledged as confirming the appearance of the interference-$0.022{\mu}m$. In establishing calculation of transformation matrix by using analogue circuit, as simulating results that used incomplete differentiation, interference is $1.7{\times}10^{-3}$ arcsec on input of the translation-$0.1{\mu}m$ and $1.4{\times}10^{4}{\mu}m$ on input of the rotation-0.5 arcsec in open-loop-control system. Also it is $4.2{\times}10^{-4}$ arcsec on input of the translation-$0.1{\mu}m$ and $5.6{\times}10^{-5}{\mu}m$ on input of the rotation-0.5 arcesc in closed-loop-control system. As closed-loop-control system is better than open-loop-control system, equivalent accordance is confirmed on original response. Finally, fundamental validity of this theory is acknowledged.

• Analytical Science and Technology
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• v.13 no.1
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• pp.72-80
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• 2000

The HS/GC/MS method was performed to analyze the volatile organic compounds in waste sludge samples. This study was performed to establish the fundamental data by studying the effects of salt, equilibrium temperature and time in the volatile organic compounds analysis. The presence of salts have been found to increase the sensitivity. The peak area is increased from 1.07 to 2.61 times by adding the salts to the water sample, compared with a salt tree sample. The recoveries of target compounds have found between 90% and 127% at sample temperature of $85^{\circ}C$ for 30 min. This HS/GC/MS method can be applied to analyze the volatile organic compounds and organohalo compounds in the environmental matrix.

• Toxicological Research
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• v.21 no.3
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• pp.209-218
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• 2005

We investigated effects of recombinant human erythropoietin (rHuEPO) on profiles of mRNA transcripts in 6 male cynomolgus (M. fascicularis) monkey's spleen for 4 weeks. Six monkeys, composed of control and treatment group (Control : M1, M2, M3: Treatment : M4, M5, M6) were intravenously administered 3 times per week without or with a dose of rHuEPO 2730 IU/0.1 ml/kg. After 4 weeks rHuEPO treatment, spleen was removed for RNA isolation. Splenic gene expression was assessed using Affymetrix U133A 2.0 arrays containing 18,400 transcripts and variants, including 14,500 well-characterized human genes. Gene expression pattern was very different between individuals even in same treatment. In rHuEPO treated groups showed number of genes were up- or down-regulated (M4: 79: M5: 48; M6: 73 genes). Six genes (epidermal growth factor receptor, calgranulin A, estrogen receptor binding site associated antigen, matrix metalloproteinase 19, zinc finger and BTB domain containing 16, progestin and adipoQ receptor) were commonly expressed in rHuEPO treated group. The different individual response could be major considering factor in monkey experiment. Further study is needed to clarify the different individual response to rHuEPO in molecular level. This study will be valuable in the fundamental understanding and validation of molecular toxicology for bio-generic drugs including rHuEPO in cynomolgus monkey.

• International Journal of Naval Architecture and Ocean Engineering
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• v.12 no.1
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• pp.376-386
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• 2020

The aim of this study was to develop a new efficient strategy that uses the Vector form Intrinsic Finite-element (VFIFE) method to conduct the static and dynamic analyses of marine pipes. Nonlinear problems, such as large displacement, small strain, and contact and collision, can be analyzed using a unified calculation process in the VFIFE method according to the fundamental theories of point value description, path element, and reverse motion. This method enables analysis without the need to integrate the stiffness matrix of the structure, because only motion equations of particles established according to Newton's second law are required. These characteristics of the VFIFE facilitate the modeling and computation efficiencies in analyzing the nonlinear dynamic problem of flexible pipe with large deflections. In this study, a three-dimensional (3-D) dynamical model based on 3-D beam element was established according to the VFIFE method. The deep-sea flexible pipe was described by a set of spatial mass particles linked by 3-D beam element. The motion and configuration of the pipe are determined by these spatial particles. Based on this model, a simulation procedure to predict the 3-D dynamical behavior of flexible pipe was developed and verified. It was found that the spatial configuration and static internal force of the mining pipe can be obtained by calculating the stationary state of pipe motion. Using this simulation procedure, an analysis was conducted on the static and dynamic behaviors of the flexible mining pipe based on a 1000-m sea trial system. The results of the analysis proved that the VFIFE method can be efficiently applied to the static and dynamic analyses of marine pipes.