• 한국세라믹학회지
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• 제45권1호
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• pp.1-29
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• 2008

In last two decades, an impressive progress has been recorded in terms of developing new materials or refining existing material composition/microstructure in order to obtain better performance in biomedical applications. The success of such efforts clearly demands better understanding of various concepts, e.g. biocompatibility, host response, cell-biomaterial interaction. In this article, we review the fundamental understanding that is required with respect to biomaterials development, as well as various materials and their properties, which are relevant in applications, such as hard tissue replacement. A major emphasize has been placed to present various design aspects, in terms of materials processing, of ceramics and polymer based biocomposites, Among the bioceramic composites, the research results obtained with Hydroxyapatite (HAp)-based biomaterials with metallic (Ti) or ceramic (Mullite) reinforcements as well as $SiO_2-MgO-Al_2O_3-K_2O-B_2O_3-F$ glass ceramics and stabilized $ZrO_2$ based bioinert ceramics are summarized. The physical as well as tribological properties of Polyethylene (PE) based hybrid biocomposites are discussed to illustrate the concept on how can the physical/wear properties be enhanced along with biocompatibility due to combined addition of bioinert and bioactive ceramic to a bioinert polymeric matrix. The tribological and corrosion properties of some important orthopedic metallic alloys based on Ti or Co-Cr-Mo are also illustrated. At the close, the future perspective on orthopedic biomaterials development and some unresolved issues are presented.

• 대한기계학회논문집
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• 제13권3호
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• pp.317-322
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• 1989

본 연구에서는 Liu의 매트릭스를 강소성 유한요소법에 도입하여 통상의 소성가공 공정중에 있는 피가공물의 3차원 변형을 실용적인 수준에서 해석 가능케 하는 강소성 유한요소법을 도입하여 통상의 소성가공 공정중에 있는 피가공물의 3차원 변형을 실용적인 수준에서 해석 가능케 하는 강소성 유한요소법을 제안하고 실례를 통하여 제안한수법에 의하여 얻어진 해의 안정성과 계산효율을 검토한다.

• KEPCO Journal on Electric Power and Energy
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• 제2권1호
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• pp.127-131
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• 2016

Polymer electrolyte membrane for unitized regenerative fuel cells requires high proton conductivity, high dimensional stability, low permeability, and low cost. However, DuPont's Nafion which is a commercial polymer electrolyte membrane has high permeability, high cost, and decreasing proton conductivity and dimensional stability over $80^{\circ}C$. To address these problems, sulfonated poly ether ether ketone (sPEEK) which is a low cost hydrocarbon polymer is selected as matrix polymer for the preparation of polymer electrolyte membrane. In addition, composite membrane with improved proton conductivity and dimensional stability is prepared by introducing sulfonated graphene oxide (sGO). The fundamental properties of polymer electrolyte membranes are analyzed by investigating membrane's water content, dimensional stability, proton conductivity, and morphology. The cell test is conducted to consider the possibility of application of sPEEK/sGO composite membrane for an unitized regenerative fuel cell.

• 한국IT서비스학회지
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• 제9권4호
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• pp.219-229
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• 2010

The Green's equivalence relations have played a fundamental role in the development of semigroup theory. They are concerned with mutual divisibility of various kinds, and all of them reduce to the universal equivalence in a group. Boolean matrices have been successfully used in various areas, and many researches have been performed on them. Studying Green's relations on a monoid of boolean matrices will reveal important characteristics about boolean matrices, which may be useful in diverse applications. Although there are known algorithms that can compute Green relations, most of them are concerned with finding one equivalence class in a specific Green's relation and only a few algorithms have been appeared quite recently to deal with the problem of finding the whole D or J equivalence relations on the monoid of all $n{\times}n$ Boolean matrices. However, their results are far from satisfaction since their computational complexity is exponential-their computation requires multiplication of three Boolean matrices for each of all possible triples of $n{\times}n$ Boolean matrices and the size of the monoid of all $n{\times}n$ Boolean matrices grows exponentially as n increases. As an effort to reduce the execution time, this paper shows an isomorphism between the R relation and L relation on the monoid of all $n{\times}n$ Boolean matrices in terms of transposition. introduces theorems based on it discusses an improved algorithm for the J relation computation whose design reflects those theorems and gives its execution results.

• 대한기계학회논문집A
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• 제26권10호
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• pp.2104-2113
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• 2002

A finite element model is developed for the process of squeeze casting of metal matrix composites (MMCs) in cylindrical molds. The fluid flow and the heat transit. are fundamental phenomena in squeeze casting. To describe heat transfer in the solidification of molten aluminum, the energy equation is written in terms of temperature and enthalpy are applied in an axisymmetric model which is similar to the experimental system. A one dimensional flow model simulates the transient metal flow. A direct iteration technique was used to solve the resulting nonlinear algebraic equations, using a computer program to calculate the enthalpy, temperature and fluid velocity. The cooling curves and temperature distribution during infiltration and solidification were calculated fer pure aluminum. Experimentally, the temperature was measured and recorded using thermocouple wire. The measured time-temperature data were compared with the calculated cooling curves. The resulting agreement shows that the finite element model can accurately estimate the solidification time and predict the cooling process.

• 한국산업융합학회 논문집
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• 제23권4_2호
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• pp.683-691
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• 2020

In the era of super-aged societies, research and development (R&D) projects related to aging are very important agenda for establishing the direction of future R&D planning and technological competitiveness in the country. In order to respond promptly to this agenda, it is essential to establish a national-level convergence R&D policy. In this study, we utilized the global R&D funding project data from major nations (US, Europe, Japan), and then standardized them with the same fields. To analyze the current status of global R&D related to aging, we performed cluster analysis based on the co-occurrence matrix to explore convergence R&D areas in the US, Europe, and Japan related to aging. In addition, comparative analysis by country suggested that different points on the interdisciplinary area and the convergence of aging-related R&D by each country. These results provide fundamental understandings for the status of convergence in aging-related global R&D, the current technology trends, and establish the direction and strategy of R&D policy.

• 대한비뇨기종양학회지
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• 제15권3호
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• pp.103-110
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• 2017

Cancer is the tissue complex consisted with heterogeneous cellular compositions, and microenvironmental cues. During the various stages of cancer initiation, development, and metastasis, cell-cell interactions as well as cell-extracellular matrix play major roles. Conventional cancer models both 2-dimensional and 3-dimensional (3D) present numerous limitations, which restrict their use as biomimetic models for drug screening and fundamental cancer biology studies. Recently, bioprinting biofabrication platform enables the creation of high-resolution 3D structures. Moreover this platform has been extensively used to model multiple organs and diseases, and this versatile technique has further found its creation of accurate models that figure out the complexity of the cancer microenvironment. In this review we will focus on cancer biology and limitations with current cancer models and we discuss vascular structures bioprinting that are critical to the construction of complex 3D cancer organoids. We finally conclude with current literature on bioprinting cancer models and propose future perspectives.

• Structural Engineering and Mechanics
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• 제10권6호
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• pp.517-532
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• 2000

A direct output feedback control scheme was recently proposed by the authors for single-story building structures resting on flexible soil body. In this paper, the control scheme is extended to mitigate the seismic responses of multi-story buildings. Soil-structure interaction is taken into account in two parts: input at the soil-structure interface/foundation and control algorithm. The former reflects the effect on ground motions and is monitored in real time with accelerometers at foundation. The latter includes the effect on the dynamic characteristics of structures, which is formulated by modifying the classical linear quadratic regulator based on the fundamental mode shape of the soil-structure system. Numerical result on the study of a $\frac{1}{4}$-scale three-story structure, supported by a viscoelastic half-space of soil mass, have demonstrated that the proposed algorithm is robust and very effective in suppressing the earthquake-induced vibration in building structures even supported on a flexible soil mass. Parametric studies are performed to understand how soil damping and flexibility affect the effectiveness of active tendon control. The selection of weighting matrix and effect of soil property uncertainty are investigated in detail for practical applications.

• 지질공학
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• 제31권4호
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• pp.479-492
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• 2021

We conducted a fundamental study on geological and rock detection via drone-based hyperspectral imaging on various types of small rock samples and interpreted the obtained information to compare and classify rocks. Further, we performed hyperspectral imaging on ten rocks, and compared the peak data value and reflectance of rocks. Results showed a difference in the reflectance and data value of the rocks, indicating that the rock colors and minerals vary or the reflectance is different owing to the luster of the surface. Among the rocks, limestone used for hyperspectral imaging is grayish white, inverted rock contains various sizes and colors in the dark red matrix, and granite comprises colorless minerals, such as white, black, gray, and colored minerals, resulting in a difference in reflectance. The reflectance of the visible ray range in ten rocks was 16.00~85.78%, in the near infrared ray range, the average reflectance was 23.94~86.43%, the lowest in basalt and highest in marble in both cases. This is because of the pores in basalt, which caused the difference in reflectance.

• 한국미생물·생명공학회지
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• 제47권3호
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• pp.423-433
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• 2019

Midgut microbiota is known to play a fundamental role in the biology and physiology of the agricultural pest, Spodoptera litura. This study reports the difference in the larval midgut microbiota of field-caught and laboratory-reared populations of S. litura by performing 16S rDNA amplicon pyrosequencing. Field populations for the study were collected from castor crops, whereas laboratory-reared larvae were fed on a regular chickpea based diet. In total, 23 bacterial phylotypes were observed from both laboratory-reared and field-caught caterpillars. Fisher's exact test with Storey's FDR multiple test correction demonstrated that bacterial genus, Clostridium was significantly abundant (p < 0.05) in field-caught larvae of S. litura as compared to that in the laboratory-reared larvae. Similarly, bacterial genera, such as Bradyrhizobium, Burkholderia, and Fibrisoma were identified (p < 0.05) predominantly in the laboratory-reared population. The Bray-Curtis dissimilarity matrix depicted a value of 0.986, which exhibited the maximum deviation between the midgut microbiota of the laboratory-reared and field-caught populations. No significant yeast diversity was seen in the laboratory-reared caterpillars. However, two yeast strains, namely Candida rugosa and Cyberlindnera fabianii were identified by PCR amplification and molecular cloning of the internal transcribed space region in the field-caught caterpillars. These results emphasize the differential colonization of gut residents based on environmental factors and diet.