• Title/Summary/Keyword: Functional modulation

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The Effect of Home-based Program For Children With Sensory Modulation Disorder (감각조절장애 아동을 위한 가정 프로그램의 효과)

  • Lee, Sung-A;Kim, Ji-Youn;Cho, Eun-Hee;Park, Kyoung-Young
    • The Journal of Korean Academy of Sensory Integration
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    • v.1 no.1
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    • pp.25-37
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    • 2003
  • Objective : To explore the effectiveness of sensory integration program of home-based outcomes in child with sensory modulation disorder. Methods : This study used the simple case study. The subjects were three children diagnosed as developmentally delayed who 14 month and 26 month males and a 15 month female. After initial evaluation, parents were educated on sensory diet and Wilbarger protocol method for 30 minutes twice for home-based treatment and asked to make out daily treatment planning. To measure improvement of children, we used for the Denver Developmental Screening Test II(DDST II), Wee Functional Independence Measure(WeeFIM), hand function, functional ability, oral motor function, Sensory Profile(Dunn, 1999). Results : After the home-based program, the scored of the Denver Developmental Screening Test II(DDST II), Wee Functional Independence Measure(WeeFIM), hand function, functional ability, oral motor function, Sensory Profile(Dunn, 1999) were higher rather than initial evaluation after the home-based program. Conclusion : The home-based program is effective for children with sensory modulation disorder but parents had to be educated by therapist specific evaluation and treatment in sensory integration.

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Novel graphene-based optical MEMS accelerometer dependent on intensity modulation

  • Ahmadian, Mehdi;Jafari, Kian;Sharifi, Mohammad Javad
    • ETRI Journal
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    • v.40 no.6
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    • pp.794-801
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    • 2018
  • This paper proposes a novel graphene-based optical microelectromechanical systems MEMS accelerometer that is dependent on the intensity modulation and optical properties of graphene. The designed sensing system includes a multilayer graphene finger, a laser diode (LD) light source, a photodiode, and integrated optical waveguides. The proposed accelerometer provides several advantages, such as negligible cross-axis sensitivity, appropriate linearity behavior in the operation range, a relatively broad measurement range, and a significantly wider bandwidth when compared with other important contributions in the literature. Furthermore, the functional characteristics of the proposed device are designed analytically, and are then confirmed using numerical methods. Based on the simulation results, the functional characteristics are as follows: a mechanical sensitivity of 1,019 nm/g, an optical sensitivity of 145.7 %/g, a resonance frequency of 15,553 Hz, a bandwidth of 7 kHz, and a measurement range of ${\pm}10g$. Owing to the obtained functional characteristics, the proposed device is suitable for several applications in which high sensitivity and wide bandwidth are required simultaneously.

Adptive Coded-Modulation in Slow Fading Channels

  • Kim, Young-Min;William C. Lindsey
    • Journal of Communications and Networks
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    • v.1 no.2
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    • pp.99-110
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    • 1999
  • The adaptive coded modulation (ACM) is a promissing way to provide a substantial improvement in spectral efficiency for slow fading channels. The basic idea is to adapt system functional-ity such as modulation, coding, information rate, and transmission power to varying channel conditions. In this work, the potential of adaptive coded modulation is investigated using cut-off rate anal-ysis in a unified way and using computer simulation. The anal-ysis includes various effects of fading channels such as feedback delay and channel prediction error. It was shown that the adaptive coded modulation can provide several folds of increase in spectral efficiency compared to a fixed coded-modulation system employing QPSK when channel varies slowly.

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Acupuncture stimulation for motor cortex activities: Evidence from 3T functional MRI study

  • 최보영;전신수;유승식;최기순;박상동;임은철;정성택;이형구;서태석
    • Proceedings of the KSMRM Conference
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    • 2003.10a
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    • pp.85-85
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    • 2003
  • Purpose: To investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. Materials and methods: The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was peformed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB34 and sham points. This study investigates the activation of the motor cortex elicited by a soft and an intensified stimulation of GB 34.Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture.

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Acupuncture Stimulation for Motor Cortex Activities: Evidence from 3T Functional MRI Study

  • Choe, Bo-Young;Jeun, Sin-Soo;Kang, Sei-Kown;Park, Gi-Soon;Chung, Sung-Taek;Yoo, Seung-Schik;Chu, Myung-Ja;Lee, Hyoung-Koo;Suh, Tae-Suk
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.352-355
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    • 2002
  • The purpose of this study was to investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was performed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB 34 and sham points. This study investigates the activation of the mortor cortex elicited by a soft and an intensified stimulation of GB 34. Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture. Group analysis from seven individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. The present study shows that acupuncture fMRI study can be safely conducted in 3T MRI environment, and acupuncture stimulation in GB34 modulates the cortical activities of the somatomotor area in human. The present findings may shed light on the CNS mechanism of motor function by acupuncture and form a basis for future investigations of motor modulation circuits in the stroke patients.

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Mechanosensitive Modulation of Receptor-Mediated Crossbridge Activation and Cytoskeletal Organization in Airway Smooth Muscle

  • Hai, Chi-Ming
    • Archives of Pharmacal Research
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    • v.23 no.6
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    • pp.535-547
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    • 2000
  • Recent findings indicate that mechanical strain (deformation) exerted by the extracellular matrix modulates activation of airway smooth muscle cells. Furthermore, cytoskeletal organization in airway smooth muscle appears to be dynamic, and subject to modulation by receptor activation and mechanical strain. Mechanosensitive modulation of crossbridge activation and cytoskeletal organization may represent intracellular feedback mechanisms that limit the shortening of airway smooth muscle during bronchoconstriction. Recent findings suggest that receptor-mediated signal transduction is the primary target of mechanosensitive modulation. Mechanical strain appears to regulate the number of functional G-proteins and/or phospholipase C enzymes in the cell membrane possibly by membrane trafficking and/or protein translocation. Dense plaques, membrane structures analogous to focal adhesions, appear to be the primary target of cytoskeletal regulation. Mechanical strain and receptor-binding appear to regulate the assembly and phosphorylation of dense plaque proteins in airway smooth muscle cells. Understanding these mechanisms may reveal new pharmacological targets for control1ing airway resistance in airway diseases.

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SER Analysis of Multi-Way Relay Networks with M-QAM Modulation in the Presence of Imperfect Channel Estimation

  • Islam, Shama N.;Durrani, Salman;Sadeghi, Parastoo
    • Journal of Communications and Networks
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    • v.18 no.5
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    • pp.677-687
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    • 2016
  • Multi-way relay networks (MWRNs) allow multiple users to exchange information with each other through a single relay terminal. MWRNs are often incorporated with capacity achieving lattice codes to enable the benefits of high-rate signal constellations to be extracted. In this paper, we analytically characterize the symbol error rate (SER) performance of a functional decode and forward (FDF) MWRN in the presence of channel estimation errors. Considering M-ary quadrature amplitude modulation (QAM) with square constellations as an important special case of lattice codes, we obtain asymptotic expressions for the average SER for a user in FDF MWRN. The accuracy of the analysis at high signal-to-noise ratio is validated by comparison with the simulation results. The analysis shows that when a user decodes other users with better channel conditions than itself, the decoding user experiences better error performance. The analytical results allow system designers to accurately assess the non-trivial impact of channel estimation errors and the users' channel conditions on the SER performance of a FDF MWRN with M-QAM modulation.

Acupuncture stimulation for motor cortex activities: Evidence from 3T functional MRI study

  • 최보영;전신수;유승식;최기순;박상동;임은철;정성택;이형구;서태석
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.75-75
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    • 2003
  • Purpose: To investigate whether or not acupuncture of GB34 produces a significant response of the modulation of somatomotor areas by functional magnetic resonance imaging (fMRI) study. Methods: The acupoint, GB34, located in the back of the knee, is known to be effective in recovering motor function after stroke. Using 3T MRI scanner, functional MR imaging of the whole brain was performed in 12 normal healthy subjects during two stimulation paradigms; acupuncture manipulation on GB 34 and sham points. This study investigates the activation of the motor cortex elicited by a soft and an intensified stimulation of GB 34. Three different paradigms were carried out to detect any possible modulation of the Blood Oxygenation Level Dependent (BOLD) response in the somatomortor area to motor stimulation through acupuncture. Results: Group analysis from seven individuals showed that bilateral sensorimotor areas (BA 3,4,6 and 7) showed stimulation related BOLD signal contrast of approximately 6% whereas very few areas were activated when sham stimulation is given. Conclusions: The present study shows that acupuncture fMRI study can be safely conducted in 3T MRI environment, and acupuncture stimulation in GB34 modulates the cortical activities of the soma- to motor area in human. The present findings may shed light on the CNS mechanism of motor function by acupuncture and form a basis for future investigations of motor modulation circuits in the stroke patients. Acknowledgement: This study was supported by a grant of the Mid and Long Term Nuclear RID Plan Program, Ministry of Science and Technology, Republic of Korea.

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The Recent Study on Pain Modulation of Acupuncture (침의 통증 조절에 관한 최근 연구 동향)

  • Kim, Jong-Yoon;Koh, Hyeong-Gyun;Nam, Sang-Soo
    • Journal of Acupuncture Research
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    • v.23 no.1
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    • pp.145-154
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    • 2006
  • Objectives : To research the recent trends of study related to pain modulation of acupuncture. Methods : We searched the resent study related to pain modulation of acupuncture. Results & Conclusion : 1) Early studies demonstrated that the analgesic effects of acupuncture are mediated by opioid peptides in the periaqueductal gray. Recent evidences show that nitric oxide plays an important role in mediating the cardiovascular responses to acupuncture stimulation through gracile nucleus-thalamic pathway. 2) Recent evidences show that acupuncture stimulate gene expression related to pain. 3) By using functional magnetic resonance and positron emission tomography, recent study suggest that acupuncture has regionally specific, quantifiable effects on pain-relevant brain structures.

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