• 제목/요약/키워드: Functional classification

검색결과 617건 처리시간 0.031초

Protein subcellular localization classification from multiple subsets of amino acid pair compositions

  • Tung, Thai Quang;Lim, Jong-Tae;Lee, Kwang-Hyung;Lee, Do-Heon
    • 한국생물정보학회:학술대회논문집
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    • 한국생물정보시스템생물학회 2004년도 The 3rd Annual Conference for The Korean Society for Bioinformatics Association of Asian Societies for Bioinformatics 2004 Symposium
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    • pp.101-106
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    • 2004
  • Subcellular localization is a key functional char acteristic of proteins. With the number of sequences entering databanks rapidly increasing, the importance of developing a powerful tool to identify protein subcellular location has become self-evident. In this paper, we introduce a novel method for predic ting protein subcellular locations from protein sequences. The main idea was motivated from the observation that amino acid pair composition data is redundant. By classifying from multiple feature subsets and using many kinds of amino acid pair composition s, we forced the classifiers to make uncorrelated errors. Therefore when we combined the predictors using a voting scheme, the prediction accuracy c ould be improved. Experiment was conducted on several data sets and significant improvement has been achieve d in a jackknife test.

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최근 재증가하고 있는 미숙아망막병증의 임상 고찰 (Assessment of retinopathy of prematurity (ROP) revisited)

  • 김정훈;유영석
    • Clinical and Experimental Pediatrics
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    • 제52권1호
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    • pp.22-27
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    • 2009
  • Retinopathy of prematurity (ROP) is a major cause of blindness that affects premature infants. With advances in neonatology, ROP is likely to emerge as the most serious problem of vision loss in children even in developed countries; such a situation could be called the third epidemic of ROP. However, controversy and uncertainty still surround favorable outcomes of ROP. For successfully controlling ROP, timely and accurate screening is crucial because early treatment leads to favorable outcomes. Standard guidelines, including ROP classification, have provided satisfactory instructions for the screening and treatment of ROP. To improve the structural and functional outcomes of ROP, optimizing the timing of surgical interventions including cryotherapy, laser-photocoagulation, encircling, and vitrectomy is essential; these interventions can prevent the sequelae of ROP. It is essential for the neonatologist and the ophthalmologist to cooperate extensively for the successful treatment of ROP.

데이터 맵핑기술을 이용한 건축물 LCCO2 평가시스템 개발 (Development of Buildng LCCO2 Assessment System through Data Mapping Technology.)

  • 금원석;태성호;노승준;방준식
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2012년도 춘계 학술논문 발표대회
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    • pp.151-152
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    • 2012
  • Recently, there are growing interests in building LCCO2 Assessment to reduce carbon emissions. However, existing methods of assessment system include inefficiency in the process of CO2 calculation requiring considerable data input. Therefore, the purpose of this study is to develop an efficient building assessment system appropriate to material production in construction stage. To that end, quantity input technology was limited to data mapping. Also quantity calculation based on work breakdown structure and item codes consisted of hierarchical structure that is based on facet classification were analyzed. As a result, connectivity links of quantity calculation and CO2 functional units through item codes for data mapping, and assessment system including calculation and database parts were developed.

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승모판 협착증의 외과적 요법 (Surgical Treatment of Mitral Stenosis)

  • 이동준
    • Journal of Chest Surgery
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    • 제11권4호
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    • pp.393-403
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    • 1978
  • A total of 54 patients with mitral stenosis were treated in the Dept.of Thoracic and Cardiovascular Surgery. Chonnam National University Hospital, during the 17-year period from Jan., 1962 to June, 1978. There were 35 men and 19 women with sex ratio of 1.8 : 1. The age of the patient varied widely from 15 years of the youngest to 48 years of the oldest. Preoper ative functional levels according to N.Y.H.A. classification were class II in 19% of cases, class III in 69%, and class IV in 12%. 53 patients were underwent closed operations; 43 cases had closed digital mitral commissurotomy and 10 cases had closed dilator mitral commissurotomy, Hospital mortality was I case (1. 9%). Results of operations were good and excellent in 48cases(91%).Most of the survivors left hospital in a good and improved condition.

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승모판막질환의 외과적 요법 (Surgical Treatment of Mitral Valvular Disease)

  • 홍종완
    • Journal of Chest Surgery
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    • 제21권2호
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    • pp.270-275
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    • 1988
  • The results of the clinical observations on the 76 cases of the mitral valvular heart disease treated in the Department of Thoracic and Cardiovascular Surgery, Chung-nam National University Hospital during the period of 3 years from June, 1983 to July, 1986, are as follows: l. Of 76 cases, 43 were male and 33 were female with sex ratio of 1.3:1. 2. The age of the patient varied widely from 12 years of the youngest to 60 years of the oldest. 3. The main clinical symptoms on admission were dyspnea on exertion[100%], palpitation[42%], generalized weakness[29%], indigestion[18%], hemoptysis[16%]. 4. The preoperative functional levels according to NYHA classification were class II, III, IV in 9%, 63%, 28% respectively. 5. All 76 patients were operated on under direct vision using extracorporeal circulation, open mitral commissurotomy was done in 15 cases, mitral valve replacement in 37 cases, mitral valve replacement and aortic valve replacement in 11 cases, mitral valve replacement and tricuspid annuloplasty in 8 cases. 6. The operative mortality was 11.8% and results of the operation were good and excellent in 65 cases of survivors.

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심장외 도관을 사용하지 않는 동맥간의 완전교정;6례 보고 (Anatomic Correction of Truncus Arteriosus without a Extracardiac Conduit - Report of 6 cases -)

  • 윤태진;김용진
    • Journal of Chest Surgery
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    • 제25권12호
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    • pp.1448-1454
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    • 1992
  • Between July, 1990 and July, 1992, 6 male patients of truncus arteriosus, whose age ranged from 2 months to 18 months, underwent total surgical correction without a extracardiac conduit. Their anatomic types were type I in 3, type II in 2 and III, in one by the Collett-Edwards classification. Surgical techniques were similar to the first description by Lecompte except for the fact that distal pulmonary arterial stumps were approximated to ventriculotomy site without Lecompte maneuver in all cases. Also in all cases, mon-ocusps were placed using glutaraldehyde fixed autologous pericardial patch directly in right ventricular outflow tract. Three patients died postoperatively and the causes of death were myocardial failure, pulmonary hypertensive crisis and pulmonary complication due to progressive pulmonary vascualr obstructive disease respectively. The three survivors have been followed up for 6~10 months with good functional results.

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Loeffler`s endocarditis 에 합병한 승모판 폐쇄부전 치험 (Surgical treatment of Loeffler`s endocarditis associated mitral insufficiency)

  • 이병우
    • Journal of Chest Surgery
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    • 제16권4호
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    • pp.526-532
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    • 1983
  • This is a report of one case of Loffler`s eosinophilic endocarditis associated with mitral insufficiency and LV thrombi treated surgically at the department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital. This patient was a 42 year old female and she has complains of dyspnea, palpitation, orthopnea and generalized edema. Above symptoms has been going for 4 months and NYHA classification was IV. On examination, blood eosinophil was 45 to 50% [WBC-9800 ]. MI and LV thrombi were confirmed by LV ventriculography and echocardiography. Pulmonary congestion and congestive cardiac failure were diagnosis by X-Ray examination, EKG finding and clinical feature and others there were no organic functional disturbance. Mitral valve replacement was performed with Ionescu-Shiley pericardial valve [29mm] replacement. Adjust thumb sized grayish brown colored two thrombi were excluded, lodged in the apex and septal endocardium of LV. Endocardial fibrosis was reliably confirmed under the gross pathology in the heart. The patient had smooth postoperative course and there were no operative complication.

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승모판막 질환의 임상적 고찰 (Clinical Analysis of Mitral Valvular Disease)

  • 김창수
    • Journal of Chest Surgery
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    • 제24권4호
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    • pp.382-389
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    • 1991
  • The clinical observations on the 63 cases of the mitral valvular heart disease treated in the department of Thoracic and Cardiovascular Surgery, Kosin medical college, during the period of 5 years from January, 1986 to December, 1989, are as follows. 1. Total 63 cases, 23 were male and 40 were female with sex ratio of 1: 1.7. 2. The age distribution was widely varied from 7 years of the youngest to 65 years oldest, average age was 35.3 year old. 3. The main clinical symptom and sign were D.O.E, general weakness, fatigability, palpitation, chest pain, hepatomegaly, pitting edema and both neck vein distension. 4. The preoperative N.Y.H.A functional classification were class II, III, IV in 28%, 54%, 16%. 5. The preoperative diagnosis were MS - 6.3%, MR - 53.9%, MSR - 36.5%, MVP - 3.1%. 6. All 63 patients were operated on the under direct vision using extracorporeal circulation, MVR in 18 cases, MVR and Tricuspid annuloplasty in 24 cases, DVR in 3 cases, DVR and Tricuspid annuloplasty in 5 cases, TVR in 1 case, Mitral annuloplasty in 4 cases, mitral valvuloplasty in 7 cases and mitral commissurotomy in 2 cases 7. The operative mortality was 7.9%, and 5 years actuarial survival rate was 89%.

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댐 저수지 내 습지 유형 및 기능평가 연구 - 보령호를 중심으로 - (Type Classification and Functional Assessment of a Dam Lake - In the Case of the Boryung Lake -)

  • 양병호;조운식;구본학
    • 한국환경복원기술학회지
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    • 제8권6호
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    • pp.80-91
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    • 2005
  • This research aims to classify wetland types and evaluate functions of a dam lake. The case study area is Boryung lake in Boryung City. In this study was carried out based upon field surveys, drawing maps and publication, and modified-RAM which can evaluate the general functions and conservation values of wetlands. Eight functions of 2-12 variables each are analyzed for assessing the wetland functions. The analysis shows that several types of wetlands were identified, such as Palustrine/ Perennial/ Hydrophytes, Palustrine/ Perennial/ Openwater, Palustrine/ Seasonal/ Herbal, Palustrine/ Seasonal/ Shrub and Scrub, Palustrine/ Seasonal/ Hydrophye, and Riparian/ Seasonal/ Shrub in the Boryung lake. The average level of functions of the wetlands is very "HIGH", and it is recommended that prompt conservation measures should be taken.