• Title/Summary/Keyword: Functional arrangement

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2D-Covalent organic frameworks for bioimaging and therapeutic applications

  • Chanho Park;Dong Wook Kim
    • 대한방사성의약품학회지
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    • 제6권2호
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    • pp.171-176
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    • 2020
  • Covalent organic frameworks (COFs) are porous crystalline polymers in which organic units are linked by covalent bonds and have a regular arrangement at the atomic level. Recently, the COFs have been much attention in bio-medical area such as bio-imaging, drug delivery, and therapeutics. These 2D nanoparticles are proving their value in nanomedicine due to their large surface area, functionalization through functional groups exposed on the surface, chemical stability due to covalent bonding, and high biocompatibility. The high ω-electron density and crystallinity of COFs makes it a promising candidate for bioimaging probes, and its porosity and large surface area make it possible to be utilized as a drug delivery vehicle. However, the low dispersibility in water, the cytotoxicity problems of COFs are still challenged to be solved in the future. In this regard, several efforts that increase the degree of dispersion through functionalization on the surface of COFs for the application to the biomedical field have been reported. In this review, we would like to describe the advantages and limitations of COFs for bio-imaging and anti-cancer treatment.

제로 웨이스트 패션 실천을 위한 패턴 커팅 설계 (Pattern-cutting design for zero-waste fashion practice)

  • 김현주;나현신
    • 복식문화연구
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    • 제31권1호
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    • pp.18-33
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    • 2023
  • Zero-waste pattern cutting is a groundbreaking sustainable fashion practice. However, few brands and designers have pursued this method because it requires creative pattern design that diverges from the existing process of using pattern slopers. Therefore, application within the fashion industry is not sufficient. Therefore, in an attempt to highlight the key characteristics of zero-waste pattern design, this study classifies and analyzes cases in which similar designs employ zero-waste pattern-cutting techniques. We hope to make zero-waste pattern design more accessible by presenting realistic pattern-cutting guidelines. To this end, theoretical research on relevant literature, previous research, and online resources and an empirical analysis of cases involving zero-waste pattern cutting were conducted in parallel. As a result of the study, we were able to classify the factors of zero-waste pattern design in terms of fabric use, design, and composition. Regarding materials, our research revealed the importance of appropriate fabric width, understanding the difference between waste minimization and minimal fabric use, and easy reuse and recycling. In terms of design, the simultaneous progress of pattern and design work, adjustable loose silhouettes, and the use of surplus fabric for functional and decorative details emerged as key characteristics. For composition, we found that size adjustment limits, arrangement irregularity, and pattern shapes were crucial elements and that various arrangements revealed unlimited design potential.

Cu/MCM-41 메조포러스 촉매 제조 및 NO 제거 특성 (Preparation and Characterization of Cu/MCM-41 Mesoporous Catalysts for NO Removal)

  • 박수진;조미화;김석;권수한
    • 공업화학
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    • 제16권6호
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    • pp.737-741
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    • 2005
  • 본 연구에서는 제조한 MCM-41에 Cu의 함량에 따른 NO의 전환율을 고찰하였다. MCM-41은 실리카 원으로 colloid silica를 사용하였고, template로 cetyltrimethylammonium chloride (CTMACl)를 사용하여 수열 합성하였으며, Cu/MCM-41은 Cu(II) acetylacetonate를 사용해서 Cu의 농도를 5, 10, 20 그리고 40%로 변화시켜 제조하였다. 표면 특성은 pH, FT-IR로 분석하였고, 육방배열의 1차원 기공 구조는 XRD로 고찰하였다. $N_2/77K$ 등온흡착 특성은 BET식과 t-plot을 이용하여 확인하였으며, NO 제거 효율은 가스크로마토그래프를 이용하여 측정하였다. 실험 결과, Si-OH와 Si-O-Si의 stretching vibration peak가 관찰되었으며, (100), (110), (200) 그리고 (210)의 육방배열의 1차원 구조를 확인하였다. Cu 금속이 도입된 MCM-41은 Cu 도입량이 증가할수록 비표면적과 미세기공부피는 감소한 반면에 NO 제거 효율은 증가하였다. 결과적으로 Cu/MCM-41의 Cu의 함량이 증가함에 따라 전체 촉매작용 반응과 NO 제거율이 증가하였다.

한국 성인 유치악자의 상악전치 위치에 관한 연구 (A Study on the Position of the Maxillary Anterior Teeth in Korean Adults with Natural Dentition)

  • 정창모;박정형
    • 구강회복응용과학지
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    • 제21권2호
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    • pp.105-111
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    • 2005
  • It is essential to establish the suitable position for artificial maxillary anterior teeth, because of not only esthetics, phonetics, mastication, but also optimal position of artificial posterior teeth for the construction of functional and esthetic prostheses. Anatomic landmarks have been used in the arrangement of artificial teeth. Such as incisive papilla and palatal rugae are useful landmarks for positioning occlusal rim and upper anterior artificial teeth because they are relatively stable and to be identified on master cast. Therefore, if average distance between maxillary anterior teeth and landmarks in dentate subjects are measured and applied, appropriate position of occlusal rim can be initially established. In this study, to present a guide to the position of the occlusal rim for upper anterior teeth of edentulous patients, horizontal distance between anatomic landmarks were measured. Maxillary casts were made in 72 Korean dentate subjects. Horizontal distance between central incisor and incisive papilla, between incisive papilla and intercanine line, and between primary palatine rugae and gingival margin of canine were measured on each cast. The results of this study were as follows ; 1. The mean distance from the incisal edge of central incisor to the posterior border of incisive papilla was 12.1 mm (Male 12.2 mm, Female 11.9 mm). 2. The mean distance between posterior border of incisive papilla and intercanine line was 3.5 mm (Male 3.4 mm, Female 3.6 mm / Left 3.6 mm, Right 3.4 mm). 3. The mean distance from the palatal gingival margin of canine to the lateral border of primary palatine rugae was 2.4 mm (Male 2.4 mm, Female 2.4 mm / Left 2.4 mm, Right 2.3 mm). 4. On all measured items, there were no significant differencies in measured values between male and female, and between left and right sides. (P>0.05).

항해안전 및 업무효율을 위한 ECDIS 사용자측면에서의 개선사항 연구 (Analysis of User Requirement for the Improvement of ECDIS to Enhance Navigational Safety and Work Efficiency)

  • 정민;박용선;강석용
    • 한국항해항만학회지
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    • 제39권3호
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    • pp.141-147
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    • 2015
  • 전자해도 시스템은 2012년 7월 1일 부로 국제항해에 종사하는 선박에 단계별로 설치가 강제화 되었다. 전자해도시스템은 백업장치를 비치할 경우 종이해도를 대체하여 사용할 수 있는 설비로 선교에서 사용의존도가 높은 핵심항해설비라고 할 수 있다. 현재 전 세계적으로 전자해도 시스템 이용 시 다양한 오류가 발생하고 있으며, 국제해사기구 및 국제수로기구에서도 문제를 인식하고 오류해결을 위한 방안을 모색하고 있는 중이다. 본 논문에서는 선장 항해사를 포함하는 사용자들을 대상으로 전자해도시스템의 이용 시 오류 발생현황과 정보표시 및 주요기능 이용 시 개선 요구사항에 관한 설문을 시행하였다. 그 결과를 기반으로 항해안전과 효율측면에서의 ECDIS 기능 개선사항을 제시하였다. 조사에서 사용자들은 ECDIS 기능사용에 있어 대부분 효율성 측면에서는 긍정적으로 평가하였으나 항해안전성에 대한 불안감을 많이 느끼는 것으로 나타났다.

치조제 흡수가 심한 환자에서 중립대를 이용한 총의치 수복 증례 (Neutral zone approach for rehabilitation of severely atrophic maxillary and mandibular ridges: A case report)

  • 이자연;최순영;이지현
    • 대한치과보철학회지
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    • 제54권4호
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    • pp.407-412
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    • 2016
  • 심하게 흡수된 치조제를 지닌 환자에게 적절한 의치를 제공하기 위한 한 가지 방법으로써 중립대 인상 기법을 이용한 의치의 제작을 고려해 볼 수 있다. 중립대 내에 인공 치아를 배열하는 것은 다음의 두 가지 목적을 이루고자 함이다. 첫째, 치아가 정상적인 근육의 기능을 방해하지 않도록 하기 위함이며, 둘째, 의치에 저항하여 가해지는 근육 조직의 힘이 안정과 유지에 더 유리하게 작용할 수 있도록 하기 위함이다. 본 증례의 환자는 심한 잔존 치조제의 흡수를 보이는 78세 여자 환자로 오랜 기간 불안정한 상 하악 총의치를 사용하고 있었다. 의치의 안정과 유지를 향상시키기 위하여 중립대 인상 기법을 통한 새로운 의치의 제작을 계획하였다. Modeling compound를 이용하여 중립대를 인기하였으며 치아 배열 후 external impression을 시행함으로써 정확한 연마면을 형성할 수 있었다. 완성된 상 하악 총의치는 보다 향상된 안정과 유지를 보였으며 환자 역시 새로 제작된 의치에 만족감을 보였기에 이를 보고하고자 한다.

비심미적인 상악 전치부 환자에서 이중 스캔을 이용한 심미보철 수복 증례 (Aesthetic restoration n patients with unaesthetic maxillary anterior teeth using double scan : A case report)

  • 고창우;김민지;양홍서;박상원;박찬;윤귀덕
    • 대한치과보철학회지
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    • 제56권2호
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    • pp.166-172
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    • 2018
  • 상악 전치부 치료 시에는 다양한 구도 속에서 체계적인 진단을 통해 적절한 형태와 배열, 색조를 가지는 수복물을 제작하여 심미적으로 환자가 만족할 수 있는 결과를 이끌어내야 한다. 이를 위해 치아 구도, 치은구도, 안면구도, 치아-안면 구도의 4가지 구도 속에서 조화를 이루는 진단 및 치료계획이 필요하다. 심미적인 욕구가 강한 경우, 주관적인 환자의 심미안을 만족시키면서 기능적인 부분을 확인하기 위해, 적절한 임시 수복물을 제작하여 기능적, 심미적 측면의 평가가 필요하다. 최종 보철물 제작에 이중 스캔을 이용하여 임시 수복물의 정보를 반영할 수 있다. 본 증례는 상악 전치부가 비심미적인 환자에서, 체계적인 심미 분석 하에 임시 수복물을 제작하고 기능적, 심미적 측면을 평가 및 수정하여, 이중 스캔을 통해 임시수복물의 정보를 최종 수복물에 반영 후 최종 수복한 증례이다.

Effects of Intensive Neuro Rehabilitation Intervention on the Motor Function Recovery and Balance in Stroke Patients

  • Lee, Je-Hyeok;Choi, Jong-Duk
    • 대한물리의학회지
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    • 제11권4호
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    • pp.41-47
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    • 2016
  • PURPOSE: The purpose of this study was to investigate the effects of differences in exercise time arrangement on the functional recovery of the lower limbs and balance of stroke patients. METHODS: The subjects of this study were 100 patients who were hospitalized in two hospitals located in Gyeonggi-do. Before the experiment, 60 of these patients who met the inclusion criteria and did not meet the exclusion criteria were randomly divided into an experimental group (n = 30), whose exercise time was concentrated, and a control group (n = 30), whose exercise time was diffuse. The two groups underwent six weeks of physical and occupational therapy four times a day for five days a week. One session of therapy took 30 minutes, including three sets of physical therapy and one set of occupational therapy. The rest time between the sessions was different for each group. The experimental group had five minutes of rest between each therapy session, and the control group had two hours of rest time between each session. The Fugl-Meyer assessment (FMA), an assessment of each patient's limit of stability (LOS), and a timed up and go test (TUG) were used as test tools. RESULTS: Both groups showed statistically significant increases in their FMA results, LOS measurements, and TUG results. The FMA results of the experimental group were significantly higher than those of the control group. CONCLUSION: Thus, concentrated exercise time was more effective than diffuse exercise time for the recovery of motor function.

성 로렌조 교회의 건축과 증축계획에 관한 연구 (A Study on the Architecture and Extension Project for the Church of St. Lorenzo)

  • 김석만
    • 건축역사연구
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    • 제23권6호
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    • pp.7-20
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    • 2014
  • The purpose of this paper is to study on the architecture and extension project for the Church of St. Lorenzo. This study is composed of a through analysis of the extension elements on the church building and extension type for extension project of the Church of St. Lorenzo. The results of study are as follows: 1. The extension project for the Church of St. Lorenzo was basically consisted of the concept of a horizontal extension plan through both the interior and exterior space of the church building. This project was the plan of concept of additional or affixing extension through existing spaces with necessary spaces to make up for the previous simple space and form as well as functional aspect. 2. The unit spaces of the nave, the aisle, the small chapels bilaterally adorning the aisles, the transept and the chapels around transepts, and the sacristies by the extension project for the Church of St. Lorenzo is composed of regulation, balance and harmony as geometric space composition according to simple proportion system on whole and parts as well as parts and parts, through the definite articulation by each space zoning. 3. The most important innovative aspect different to previous churches in the extension project for the Church of St. Lorenzo is the compositive system of each other symmetrical spaces through long centrical axis of central part, applying the module system for horizontal arrangement. In particular, the use of regular module on repetition and proportion of rhythm from architectural composition system was precisely composed with the alter that consists of visual focus to express more accurate perspective.

다시점 가시영역 분석도구설정에 관한 기초연구 - 3D게임엔진을 이용한 래스터 연산방식을 중심으로 - (A study for the establishment of analysis tool for the visible area of three dimensional space - Based on the Raster operation using 3D game engine -)

  • 김석태;전한종
    • 한국실내디자인학회논문집
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    • 제16권5호
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    • pp.38-46
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    • 2007
  • In the late 1970s, the method of quantitative and scientific space structural analysis based on graph theory was introduced to the process of space design, which arranges design and functional elements, as relying heavily on intuition could produce errors due to unverified experiences and prejudices of the designer. As the method of space analysis is complex and hard to express visually and requires repetitive operations, it was discussed theoretically only. However, with the development of computer performance and graphic in recent years, visualization became possible. But the method of visual structural analysis of space is at the level of two dimensions and it is not easy to get accurate data when it is applied to limited three dimensional space such as an interior space. For the visual structural analysis of space, this study presents 4 indices including visibility volume level, pure visibility connection frequency, effective visibility connection frequency, and path visibility connection frequency. This study also presents space division using three dimensional arrangement rather than the existing vector operation method and raytracing algorithm at the lattice constant. Based on this, an analysis tool for the visible regions of three dimensional space that is capable of evaluating at multiple points by using three dimensional game engine and presentation tool that allows the analyzer to interpret the data effectively is made. It is applied to 2 prototype models by displacing Z axis, and the results are compared with UCL Depthmap to verify the validity of data and evaluate its usefulness as a multidimensional, multi-view space analysis tool.