• 대한안전경영과학회지
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• 제13권1호
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• pp.203-209
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• 2011

This study develops three new models that are practically applicable to three stages of Taguchi's robust design, which includes system design, parameter design and tolerance design. In system design, the Multiple Loss Function Analysis(MLFA) and Overall Loss Index(OLI) which reflect upon weight of characteristics and importance of specification are developed. Moreover parameter design presents Process Capability Index(PCI), $C_{PUK}$ and $C_{PLK}$, in order to segregate Signal-To-Noise Ratio(SNR) into accuracy and precision for an evaluation of relative comparison. In addition, tolerance design presents the new model of allowance computation for assembled product which is primarily derived from safety margin(SM) considering functional limit and specification. The guideline of those three new models, which include systematic charts and applicable illustrations, offers convenience for practitioners in the field. Hence, the practical applications could be made with the steps of robust designs such as system design, parameter design and specification allowance design.

• Elastomers and Composites
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• 제55권4호
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• pp.306-313
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• 2020

To investigate the reinforcing effects of functional fillers in nitrile rubber (NBR) materials, high-structure carbon black (HS45), coated calcium carbonate (C-CaCO3), silica (200MP), and multi-walled carbon nanotubes (MWCNTs) were used as functional filler, and carbon black (SRF) as a common filler were used for oil-resistant rubber. The curing and mechanical properties of HS45-, 200MP-, and MWCNT-filled NBR compounds were improved compared to those of the SRF-filled NBR compound. The reinforcing effect also increased with a decrease in the particle size of the fillers. The C-CaCO3-filled NBR compound exhibited no reinforcing effect with increasing filler concentration because of their large primary particle size (2 ㎛). The reinforcing behavior based on 100% modulus of the functional filler based NBR compounds was compared by using several predictive equation models. The reinforcing behavior of the C-CaCO3-filled NBR compound was in accordance with the Smallwood-Einstein equation whereas the 200MP- and MWCNT-filled NBR compounds fitted well with the modified Guth-Gold (m-Guth-Gold) equation. The SRF- and HS45-filled NBR compounds exhibited reinforcing behavior in accordance with the Guth-Gold and m-Guth-Gold equations, respectively, at a low filler content. However, the values of reinforcement parameter (100Mf/100Mu) of the SRF- and HS45-filled NBR compounds were higher than those determined by the predictive equation model at a high filler content. Because the chains of SRF composed of spherical filler particles are similarly changed to rod-like filler particles embedded in a rubber matrix and the reinforcement parameter rapidly increased with a high content of HS45, the higher-structured filler. The reinforcing effectiveness of the functional fillers was numerically evaluated on the basis of the effectiveness index (��SRF/��f) determined by the ratio of the volume fraction of the functional filler (��f) to that of the SRF filler (��SRF) at three unit of reinforcing parameter (100Mf/100Mu). On the basis of their effectiveness index, MWCNT-, 200MP-, and HS45-filled compounds showed higher reinforcing effectiveness of 420%, 70%, and 20% than that of SRF-filled compound, respectively whereas C-CaCO3-filled compound exhibited lower reinforcing effectiveness of -50% than that of SRF-filled compound.

• 핵의학기술
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• 제19권2호
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• pp.81-86
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• 2015

동적 타액선 신티그라피는 비침습적인 방법으로 타액선의 기능을 평가하는데 널리 사용되어 왔다. 본 연구에서는 타액선 신티그라피의 시간-방사능 곡선에서 다양한 기능적 매개변수지표를 측정하고 구강건조증 환자 그룹과 건강한 Control 그룹과 비교를 통해 유용성을 알아보고자 한다. 2014년 12월부터 2015년 2월까지 구강 건조증으로 내원하여 동적 타액선 신티그라피를 시행한 환자 그룹 30명과 건강한 Control 그룹 10명을 대상으로 하였다. 검사방법은 370 MBq의 $^{99m}Tc$-과산화테크네슘을 정맥으로 순간 주사 후 약 30분간 동적 타액선 신티그라피를 연속 촬영하였으며, 주사 후 20분째에 최타 자극제로 비타민C 파우더를 이용하였다. 정량분석은 이하선과 악하선의 시간-방사능 곡선을 통해 기능적 매개변수 지표를 획득하고, 통계 프로그램을 이용하여 구강 건조증 환자와 건강한 Control 그룹과 비교하였다. 동적 타액선 신티그라피에서 이하선과 악하선의 기능적 매개변수 지표인 섭취율(Uptake Ratio, UR), 최대 방사능 시간(Time at Maximum counts, Tmax), 최소 방사능 시간(Time at Minimum counts, Tmin), 최대 축적율(Maximum Accumulation, MA), 축적속도(Accumulation Velocity), 최대 배출율(Maximum Secretion, MS), 최대 자극 배출율(Maximum Stimulation Secretion, MSS), 배출속도(Secretion Velocity, SV)를 각각 측정하였다. 구강 건조증 환자와 건강한 Control 그룹간의 이하선과 악하선의 기능적 매개변수 지표 비교에서는 최소 방사능 시간을 제외한 모든 지표에서 건강한 Control 그룹이 환자 그룹에 비하여 유의성 있게 높게 측정되었으며, 시간에 따른 변화량도 Control 그룹이 환자 그룹에 비하여 유의성 있게 변화량이 크게 측정 되었다. 동적 타액선 신티그라피에서 다양한 기능적 매개변수 지표를 이용한 정량분석은 구강 건조증 환자의 타액선 기능을 평가하는데 객관적이고 표준화된 정보를 제공해 줄 것으로 사료된다.

• Structural Engineering and Mechanics
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• 제88권4호
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• pp.355-368
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• 2023

Employing the non-local strain gradient theory (NSGT), this paper investigates the nonlinear resonance characteristics of functionally graded material (FGM) nanoshells with initial geometric imperfection for the first time. The effective material properties of the porous FGM nanoshells with even distribution of porosities are estimated by a modified power-law model. With the guidance of Love's thin shell theory and considering initial geometric imperfection, the strain equations of the shells are obtained. In order to characterize the small-scale effect of the nanoshells, the nonlocal parameter and strain gradient parameter are introduced. Subsequently, the Euler-Lagrange principle was used to derive the motion equations. Considering three boundary conditions, the Galerkin principle combined with the modified Lindstedt Poincare (MLP) method are employed to discretize and solve the motion equations. Finally, the effects of initial geometric imperfection, functional gradient index, strain gradient parameters, non-local parameters and porosity volume fraction on the nonlinear resonance of the porous FGM nanoshells are examined.

• Asian Spine Journal
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• 제12권6호
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• pp.1085-1091
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• 2018

Study Design: Case-control. Purpose: To determine optimal cut-off value for body mass index (BMI) in predicting surgical success in patients with lumbar spinal canal stenosis (LSCS). Overview of Literature: BMI is an essential variable in the assessment of patients with LSCS. Methods: We conducted a prospective study with obese and non-obese LSCS surgical patients and analyzed data on age, sex, duration of symptoms, walking distance, morphologic grade of stenosis, BMI, postoperative complications, and functional disability. Obesity was defined as BMI of ${\geq}30kg/m^2$. Patients completed the Oswestry Disability Index (ODI) questionnaire before surgery and 2 years after surgery. Surgical success was defined as ${\geq}30%$ improvement from the baseline ODI score. Receiver operating characteristic (ROC) analysis was used to estimate the optimal cut-off values of BMI to predict surgical success. In addition, correlation was assessed between BMI and stenosis grade based on morphology as defined by Schizas and colleague in total, 189 patients were eligible to enter the study. Results: Mean age of patients was $61.5{\pm}9.6years$. Mean follow-up was $36{\pm}12months$. Most patients (88.4%) were classified with grades C (severe stenosis) and D (extreme stenosis). Post-surgical success was 85.7% at the 2-year follow-up. A weak correlation was observed between morphologic grade of stenosis and BMI. Rates of postoperative complications were similar between patients who were obese and those who were non-obese. Both cohorts had similar degree of improvement in the ODI at the 2-year followup. However, patients who were non-obese presented significantly higher surgical success than those who were obese. In ROC curve analysis, a cut-off value of ${\leq}29.1kg/m^2$ for BMI in patients with LSCS was suggestive of surgical success, with 81.1% sensitivity and 82.2% specificity (area under the curve, 0.857; 95% confidence interval, 0.788-0.927). Conclusion: This study showed that the BMI can be considered a parameter for predicting surgical success in patients with LSCS and can be useful in clinical practice.

• 한국군사과학기술학회지
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• 제14권3호
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• pp.441-457
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• 2011

In this study, the axiomatic design(AD) method is applied to construct the hierarchical structure of evaluation criteria and the AHP method is used to calculate the weights of criteria in order to develop the proposal evaluation index for the overseas weapon system purchasing projects. The common evaluation items as main categories are selected through the review of evaluation criteria from the previous works and projects, relevant regulations and defense policy, and the design matrix using fuzzy concept is established and evaluated by the expert group in each design phase to determine the independency, that is the satisfaction of decoupled or uncoupled design, for each criteria in the same hierarchy when they are derived from the main categories. The establishment of decoupled or uncoupled design matrix provides mutually exclusiveness of how small number of DPs can be accounted for FRs within the same hierarchy. The proposal evaluation index developed in this study will be used as a general proposal evaluation index for the overseas weapon system purchasing projects which there are no systematically established evaluation tools.

• Korean Journal of Radiology
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• 제23권10호
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• pp.986-997
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• 2022

Objective: Whether metabolic redistribution occurs in patients with white matter hyperintensities (WMHs) on magnetic resonance imaging (MRI) is unknown. This study aimed 1) to propose a measure of the brain metabolic network for an individual patient and preliminarily apply it to identify impaired metabolic networks in patients with WMHs, and 2) to explore the clinical and imaging features of metabolic redistribution in patients with WMHs. Materials and Methods: This study included 50 patients with WMHs and 70 healthy controls (HCs) who underwent ¹⁸F-fluorodeoxyglucose-positron emission tomography/MRI. Various global property parameters according to graph theory and an individual parameter of brain metabolic network called "individual contribution index" were obtained. Parameter values were compared between the WMH and HC groups. The performance of the parameters in discriminating between the two groups was assessed using the area under the receiver operating characteristic curve (AUC). The correlation between the individual contribution index and Fazekas score was assessed, and the interaction between age and individual contribution index was determined. A generalized linear model was fitted with the individual contribution index as the dependent variable and the mean standardized uptake value (SUV_mean) of nodes in the whole-brain network or seven classic functional networks as independent variables to determine their association. Results: The means ± standard deviations of the individual contribution index were (0.697 ± 10.9) × 10^-3 and (0.0967 ± 0.0545) × 10^-3 in the WMH and HC groups, respectively (p < 0.001). The AUC of the individual contribution index was 0.864 (95% confidence interval, 0.785-0.943). A positive correlation was identified between the individual contribution index and the Fazekas scores in patients with WMHs (r = 0.57, p < 0.001). Age and individual contribution index demonstrated a significant interaction effect on the Fazekas score. A significant direct association was observed between the individual contribution index and the SUV_mean of the limbic network (p < 0.001). Conclusion: The individual contribution index may demonstrate the redistribution of the brain metabolic network in patients with WMHs.

• 대한한방내과학회지
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• 제32권4호
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• pp.584-598
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• 2011

Objectives : Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disease. The aim of this study was to analyze the characteristics of functional dyspepsia patients and evaluate changes in symptoms, quality of life, and electrogastrography parameters before and after oriental medical interventions. Methods : We recruited forty-six functional dyspepsia patients who visited gastroenterology clinic in the oriental medicine hospital of Kyung Hee University between November 2009 and February 2011. Patients were assessed for their frequency of dyspepsia (based on short form-Leeds Dyspepsia Questionnaire: SF-LDQ), quality of life (based on functional dyspepsia-related quality of life questionnaire: FD-QoL), gastric motility (based on electrogastrography: EGG) on the first visit. Then, the effect of oriental medical interventions was evaluated using EGG on the second visit. Results : The majority of patients had symptoms of nausea and indigestion. The largest decrease in EGG parameters was found in the indigestion group. The frequency of regurgitation and postprandial EGG power % bradygastria showed a significant correlation. Also, significant correlations were found between some items of FD-QoL and some EGG parameters. Compared to the EGG parameters before oriental medical interventions, some parameters after treatment had positive results, implying the improvement of gastric motility disorder. We also found improvement of EGG parameters in both digestant medicinal group and digestant combined with qi-tonifying medicinal group. Conclusions : The results of this study suggest that clinical application of EGG can be an objective diagnostic tool in functional dyspepsia patients visiting oriental medical hospital.

• Steel and Composite Structures
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• 제42권3호
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• pp.397-405
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• 2022

The existing researches on the dynamics of the fluid-conveying pipes only focus on stability and vibration problems, and there is no literature report on the wave propagation of the fluid-conveying pipes. Therefore, the purpose of this paper is to explore the propagation characteristics of longitudinal and flexural waves in the fluid-conveying pipes. First, it is assumed that the material properties of the fluid-conveying pipes vary based on a power function of the thickness. In addition, it is assumed that the material properties of both the fluid and the pipes are closely depended on temperature. Using the Euler-Bernoulli beam equation and based on the linear theory, the motion equations considering the thermal-mechanical-fluid coupling is derived. Then, the exact expressions of phase velocity and group velocity of longitudinal waves and bending waves in the fluid-conveying pipes are obtained by using the eigenvalue method. In addition, we also studied the free vibration frequency characteristics of the fluid-conveying pipes. In the numerical analysis, we successively studied the influence of temperature, functional gradient index and liquid velocity on the wave propagation and vibration problems. It is found that the temperature and functional gradient exponent decrease the phase and group velocities, on the contrary, the liquid flow velocity increases the phase and group velocities. However, for vibration problems, temperature, functional gradient exponent parameter, and fluid velocity all reduce the natural frequency.

• Physical Therapy Rehabilitation Science
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• 제11권4호
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• pp.517-525
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• 2022

Objective: The rehabilitation protocols for functional recovery have been emphasized after total knee arthroplasty, and Pilates is in the spotlight as a safe and easily modified exercise method. The purpose of this study was to investigate the effects of mat Pilates exercise on lower extremity function, postural balance, and walking in the individuals with total knee arthroplasty. Design: One group pretest-posttest design. Methods: Eighteen older women with unilateral total knee arthroplasty was recruited in the study. The subjects were evaluated on lower extremity function, postural balance, and walking before and after mat Pilates exercise. All subject performed one hour mat Pilates exercise, 3 times a week for 8 weeks. Mat Pilates exercises were focused on core stability and lower extremity strengthening and, more dynamic movements were added to increase the difficulty of movements every two weeks. The lower extremity function was measured using the Western Ontario and McMaster Osteoarthritis Index (WOMAC), knee joint position sense, and five times sit-to-stand test. Postural balance was assessed by single leg stance test, functional reach test, and timed up and go test. Walking was measured by OptoGait system to temporospatial parameter. Results: The lower extremity function, postural balance, and walking were significantly improved after mat Pilates exercise, except for five times sit-to-stand test (p<0.05). Conclusions: This study demonstrated that the mat Pilates exercise was a useful method to improve lower extremity function, postural balance, and walking in the older women with unilateral total knee arthroplasty.