• Bulletin of the Korean Chemical Society
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• 제24권11호
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• pp.1649-1654
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• 2003

We have investigated substituent effect on the stabilization energies, and nucleus-independent chemical shifts of pentafulvalenes and on the electronic structures of the corresponding polypentafulvalenes to design environmentally stable semiconductive or conductive polymers. Geometrical optimizations of the molecules were carried out at the density functional level of theory with B3LYP hybrid functional and 6-311+G(d) basis set. Stabilization energies were estimated using isodesmic and homodesmotic reactions. As a criterion of aromaticity nucleus-independent chemical shifts of the molecules were computed using GIAO approach. For the polymers the geometrical parameters were optimized through AM1 band calculations and the electronic structures were obtained through modified extended Huckel band calculations. It is found that strong electronwithdrawing substituents increase isodesmic and homodesmotic stabilization energies of pentafulvalene, though it does not increase the aromaticity. Nitro-substituted pentafulvalene is estimated to have stabilization energy as much as azulene. However, substitution either with electron-donating groups or with electronwithdrawing groups does not significantly affect the electronic structures of polypentafulvalene and poly (vinylenedioxypentafulvalene).

• 보건교육건강증진학회지
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• 제31권3호
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• pp.1-13
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• 2014

Objectives: This study was performed to identify factors related to perceived health status among patients with type 2 diabetes. Methods: This is cross-sectional observational study. Respondents were 106 visitors in an outpatient diabetes clinic of a university hospital. Self-report questionnaire which included general information inquiry, diabetes-related, sociopsychological factors, functional health literacy and perceived health status was used for this study. The data was analyzed by using descriptive statistics, independent simple t-test, one-way ANOVA, and hierarchical multiple linear regression. All analysis were conducted using SAS 9.3. Results: Among the respondents, 43.4% engaged in poorly perceived health status. After adjusting for control variables, functional health literacy is significantly related to perceived health status(${\beta}$=0.095, p=0.016). Conclusion: Independent of diabetes-related, sociopsychological factors, higher functional health literacy is associated with better perceived health status of patients with type 2 diabetes. In order to improve perceived health status in the type 2 diabetes patients, it is necessary to develop strategy to enhance the functional health literacy.

• Journal of Microbiology and Biotechnology
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• 제25권9호
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• pp.1578-1582
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• 2015

Granzyme A (GzmA) was identified as a cytotoxic T lymphocyte protease protein expressed in the nucleus. A number of nuclear proteins are well known as GzmA substrates, and GzmA is related with caspase-independent apoptosis. Histones H1, H2B, and H3 were identified as GzmA substrates through in vitro experiment with purified nucleosome. Here, we demonstrated that histone H3 was cleaved by GzmA in vivo during staurosporine-induced cell death. Moreover, histone H3 cleavage was blocked by the GzmA inhibitor nafamostat mesylate and by GzmA knockdown using siRNA. Taken together, we verified that histone H3 is a real substrate for GzmA in vivo in the Raji cells treated by staurosporin.

• World Technopolis Review
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• 제8권1호
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• pp.21-42
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• 2019

The purpose of this research was to investigate the factors influencing global expansion/scalability of Kenyan Small and Medium Enterprises (SMEs). Factor analysis and multiple/multivariate regression analysis to determine the functional relationship between independent variables (factors) and the dependent variable was used. The independent variables were: innovation & technology, fitness/appropriateness of management, global marketing strategy; and support environment and the dependent variable, global expansion/scalability. Data was collected from a survey of randomly selected firms of 205, drawn from a population of 440 firms from Kenya Manufacturers Directory, with 175 firms responding. The key findings from the research in relation to Kenyan SMEs were that: there is a functional relationship between global market strategy and global expansion; there is a functional relationship between innovation and technology orientation and global expansion, there is no significant functional relationship between supportive environment of firms and their global expansion; and there is no significant functional relationship between fitness/appropriateness of management and global expansion/scalability. The implications for practice is that the ranking of the factors in order of priority supports focusing concern on the orientation of business strategy toward global market strategy, market research geared at obtaining foreign market intelligence, innovation and technology, product adaptation, service orientation, collaborative ventures, and long-range vision as key factors in making Kenyan firms successful in the international market. The implication for policy and practice is that there is need for collaboration between industry and government in pursuing policies for global expansion/scalability and among SMEs and large enterprises particularly in areas of rapid technological change.

• 한국전문물리치료학회지
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• 제14권1호
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• pp.21-27
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• 2007

The purpose of this study was to evaluate isometric trunk extension strength in hemiplegic patients, and to compare that with normal subjects to find a correlation between trunk extension strength and the functional independent degree in hemiplegic patients. Fifteen hemiplegic male patients (mean age $55.2{\pm}10.2$ years) and twenty-five healthy male subjects (mean age $54.6{\pm}10.3$ years) completed isometric trunk extension. Strength was measured at 0, 12, 24, 36, 48, 60, and 72 degrees of trunk flexion. The functional independent degree was assessed by Functional Independence Measure (FIM). Mean isometric trunk extension strength was 91.2 ft-lbs, 120.7 ft-lbs, 142.3 ft-lbs, 156.4 ft-lbs, 173.5 ft-lbs, 184.1 ft-lbs, and 195.3 ft-lbs in the hemiplegic patients group, and 135.6 ft-lbs, 175.6 ft-lbs, 204.4 ft-lbs, 221.9 ft-lbs, 231.2 ft-lbs, 246.8 ft-lbs, and 259.7 ft-lbs in the normal subjects group. The values of isometric trunk extension strength had a descending linear correlation pattern from trunk flexion angle to extension angle. Trunk extension strength in hemiplegic patients was significantly lower than that of normal subjects (p<.05) but did not correlate with the FIM total score (p>.05). Therefore, the isometric trunk extension strength in hemiplegic patients was lower than that of normal subjects and did not correlate with the functional independent degree.

• 한국수학교육학회지시리즈A:수학교육
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• 제43권2호
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• pp.177-186
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• 2004

In this paper, we introduce new functional definitions for school geometry based on DGS (dynamic geometry system) teaching-learning environment. For the vertices forming a geometric figure, we first consider the relationship between the independent vertices and dependent vertices, and using this relationship and educational considerations in DGS, we introduce functional definitions for the geometric figures in terms of its independent vertices. For this purpose, we design a new DGS called JavaMAL MicroWorld. Based on the needs of new definitions in DGS environment for the student's construction activities in learning geometry, we also design a new DGS based geometry curriculum in which the definitions of the school geometry are newly defined and reconnected in a new way. Using these funct onal definitions, we have taught the new geometry contents emphasizing the sequential expressions for the student's geometric activities.

• 한국보건간호학회지
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• 제18권1호
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• pp.5-13
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• 2004

Purpose: This study was performed to examine the relationship between caregiver burden and health-related quality of life (HRQOL) in family caregivers of stroke patients in the community. Methods: Subjects were 33 stroke patients who had a experience of hospitalization during last 1 year and their family. Data were obtained from personal interview by nursing students in October, 2003. We assessed the functional status of stroke patients, caregiver burden and the HRQOL of caregivers using SF-8. Results: A higher subjective burden was related to dependent functional status of patients than independent(P<.01). The independent cognitive function of stroke patients and good health of caregivers were related to high HRQOL of caregivers. PCS and MCS of HRQOL were negatively correlated to subjective burden, -.34(p<.01) and -.37(p<.05). Conclusion: We founded functional status of stroke patients. caregiver burden and HRQOL of caregivers were related to each other. To improve the HRQOL of caregiver, decreasing burden of caregivers and the functional status improvement of stroke patients must be considered.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2004년도 추계학술대회논문집
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• pp.267-270
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• 2004

In Micro injection process, it is needed to the technique of making micro die, Rapid Thermal Pressing (RTP) and other techniques. Those techniques are independent. But the mutual connected system of techniques is needed. The target of this paper is the design of micro mold and the development of the entire micro injection techniques for functional polymer.

• 한국멀티미디어학회논문지
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• 제24권5호
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• pp.684-694
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• 2021

Resting-state Functional Magnetic Resonance Imaging(fMRI) data detects the temporal correlations in Blood Oxygen Level Dependent(BOLD) signal and these temporal correlations are regarded to reflect intrinsic cortical connectivity, which is deactivated during attention demanding, non-self referential tasks, called Default Mode Network(DMN). The relationship between fMRI and anatomical connectivity has not been studied in detail, however, the preceded studies have tried to clarify this relationship using Diffusion Tensor Imaging(DTI) and fMRI. These studies use method that fMRI data assists DTI data or vice versa and it is used as guider to perform DTI tractography on the brain image. In this study, we hypothesized that functional connectivity in resting state would reflect anatomical connectivity of DMN and the combined images include information of fMRI and DTI showed visible connection between brain regions related in DMN. In the previous study, functional connectivity was determined by subjective region of interest method. However, in this study, functional connectivity was determined by objective and advanced method through Independent Component Analysis. There was a stronger connection between Posterior Congulate Cortex(PCC) and PHG(Parahippocampa Gyrus) than Anterior Cingulate Cortex(ACC) and PCC. This technique might be used in several clinical field and will be the basis for future studies related to aging and the brain diseases, which are needed to be translated not only functional connectivity, but structural connectivity.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2002년도 추계학술발표대회
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• pp.161-166
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• 2002

Functional ability is an important criterion to predict the capability of older persons to maintain independent living in the community setting. This study focused on the effect of built-environment features to ameliorate declines in functional ability and reduce the likelihood of relocation. Using longitudinal data from the Asset and Health Dynamics Among the Oldest Old (1993, 1995), relocation was analyzed for 6,225 respondents aged 70 or older. Findings are that while functional decline in household activities of daily living among older persons increased their residential moves in the community, functional declines in basic activities of daily living, household activities of daily living, and advanced activities of daily living among them increased their entrance into an institutional care facility However, they were less likely to enter an institutional care facility when their home was equipped with built-environment features such as street level ramps, special railings, modifications to allow someone in a wheelchair, grab bars or shower seat in the bathroom, and special call device or system to get help.