• Journal of Yeungnam Medical Science
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• 제22권2호
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• pp.183-190
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• 2005

생후 4주 이내의 신생아 중 재태 연령 37주 이상의 만삭신생아에서 발생한 기흉의 발생 정도 및 임상 양상을 알아보고자, 2000년 1월부터 2004년 12월까지 만 5년간 증상을 가진 기흉 환아 32례를 대상으로, 자발성 기흉 군과 이차성 기흉 군으로 나누어 후향적으로 조사하였다. 발생한 기흉 환아 32례 중 자발성 기흉은 10례(31%), 이차성 기흉은 22례(69%)였으며, 전체 해당기간 신생아실 총 입원 환아에 대한 자발성 기흉의 발생률은 0.4%였다. 이차성 기흉 환아의 원인 질환은 폐렴 7례(31.8%), 태변흡인증후군 5례(22.7%), 신생아 일과성 빈호흡 5례(22.7%), 신생아 호흡곤란 증후군 4례(18.2%), 폐기종 1례(4.5%) 순으로 나타났으며, 대상 환아 22례 중 12례(54.5%)는 기계적 환기 요법 및 양압 손상과 관련되어 나타났다. 자발성 기흉 군에서 전체 입원 기간과 흉관 삽관 시 흉관 유치 기간이 의미 있게 짧은 것 이외에는 다른 임상 양상이나 치료 방법에서는 양 군 간의 유의한 차이는 없었다. 신생아기에 발생한 기흉은 발생 원인에 관계없이 주의 깊은 관찰과 즉각적이고 적절한 처치가 필요할 것으로 생각된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권5호
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• pp.453-459
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• 2019

Purpose: Jaundice accounts for most hospital admissions in the neonatal period. Nowadays, in addition to phototherapy, other auxiliary methods are used to reduce jaundice and the length of hospitalization. This study aimed to investigate the effect of probiotics on the treatment of hyper-bilirubinemia in full-term neonates. Methods: In this randomized clinical trial, 83 full-term neonates, who were admitted to the hospital to receive phototherapy in the first 6 months of 2015, were randomly divided into two groups: synbiotic (SG, n=40) and control (CG, n=43). Both groups received phototherapy but the SG also received 5 drops/day of synbiotics. Serum bilirubin, urine, stool, feeding frequency, and weight were measured daily until hospital discharge. A p-value<0.05 was considered statistically significant. Results: The mean total serum bilirubin in the SG was lower than that in the CG ($9.38{\pm}2.37$ and $11.17{\pm}2.60mg/dL$, respectively). The urine and stool frequency in the SG was significantly higher than that in the CG (p<0.05). The duration of hospitalization in the SG was shorter than that in the CG. Conclusion: Use of synbiotics as an adjuvant therapy had a significant treatment effect on jaundice in full-term neonates. Further studies including larger samples with long follow-up periods are essential to confirm the benefits of routine use of synbiotics in neonatal patients with jaundice.

• 부모자녀건강학회지
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• 제12권2호
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• pp.160-176
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• 2009

Purpose: The purpose of this study was to identify patterns and trends of studies, analyze the research, and improve direction of nursing research related to the neonatal pain relief intervention in Korea. Method: The studies were selected from dissertation, nursing journals and others in Korea. Result: Until 1995, there were no studies related to the neonatal pain relief intervention. The most studies have been increased rapidly after 2005. Pure of true experimental design of research design was used 5, Quasi experimental design was 7, preexperimental design was 7. Participants were preterm baby was 8, full-term baby was 9, and preterm and full-term baby was 2. Utilization of instruments as follows: NIPS, PIPP, ABSS, NFCS, pulse oximeter, EKG monitoring, and stethoscope. Contents of the research studies were classified 4 different types, such as studies of about the effect of auditory stimulation, taste stimulation, tactile stimulation, and topical anesthetic cream. The results of 25 studies were effective for the neonatal pain relief, but the results of 5 studies weren't. Conclusion: In the future studies need to develop the various instrument which is assessment of neonatal pain. It is important to the integrated by meta analysis. Additionally, we should develop protocol nursing intervention for the effective pain release.

• 대한간호학회지
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• 제37권5호
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• pp.781-789
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• 2007

Purpose: The study was conducted to investigate the skin hydration level in various body sites and identify the influencing factors in neonates. Methods: An exploratory comparison study was designed to measure the stratum corneum hydration, using a National DM-R2 on the forehead, abdomen, buttocks, and the back of the hands and feet of 198 neonates including 92 premature infants. Results: The results showed 32.7%-36.5% of stratum corneum hydration for all sites. Premature infants revealed a higher hydration level on the peripheral sites (dorsal hand and feet) than those of the full-term infants, possibly resulting from therapeutic regimens including an incubator or radiant warmer. Infants in an incubator showed a higher hydration level than those in radiant warmers, suggesting more attention to fluid management for infants in the open environment. In addition, all stratum corneum hydration measurements except one, from the forehead, showed a positive correlation with postnatal age in full-term infants while showing no relation to any measurements in premature infants. Conclusion: The study demonstrated the very low skin hydration levels in hospitalized neonates, particularly in premature neonates with more susceptible skin hydration instability despite therapeutic interventions for fluid balance. More vigilant fluid management is imperative in neonates, particularly those in the open environment.

• 대한간호학회지
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• 제33권1호
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• pp.51-59
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• 2003

Purpose: The purpose of the study is to investigate the relationship between total serum bilirubin(TSB) and transcutaneous bilirubinometry(TcB) in neonates with jaundice. Method: TcB from various sites(forehead, sternum, abdomen, buttock, hand, dorsalis-pedia) was measured using a JM-102 in a total of 102 neonate, 42 female and 60 male, with the mean 37.5 gestational week and the mean 2,903 gram of birth weight, as well as TSB from capillary punctures. Result: The mean bilirubin was 11.73 in serum, 20.55 on the forehead, 17.23 on the sternum, 16.19 on the abdomen, 18.22 on the buttock, 15.83 on the hand and 15.49 on the dorsalis-pedia. The relationship between TSB and TcBs were formulated by simple regression with 0.406 < r < 0.668(p < .000). A higher relationship was revealed between TSB and TCB at the forehead in infants of full-term, ABO incompatibility, and Hb greater than 16 mg/dl(r =0.725, 0.790, and 0.717, retrospectively). Phototherapy altered the measurement of TcB per site. Conclusion: TcB on the forehead is a reliable, noninvasive and convenient measurement of TSB in normal infants(Institutions need to establish quantitative equations representing the specific relationship between TSB and TCB according to the hemodynamic problems of infants such as ABO incompatibility, or low Hb).

• Neonatal Medicine
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• 제28권2호
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• pp.77-82
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• 2021

We present the case of a healthy 28-day-old female full-term neonate who was admitted to the neonatal intensive care unit for severe metabolic acidosis, hypoglycemia, and an initial sinus rhythm. The first diagnostic hypothesis was hypovolemic shock, and fluid resuscitation was started immediately. During fluid therapy, cardiovascular collapse occurred with supraventricular tachycardia. The latter was successfully treated with adenosine and beta-blockers. After 8 days, electrocardiography showed ventricular pre-excitation, and Wolff-Parkinson-White syndrome was diagnosed. A novel variant of the MYL2 gene that is related to hypertrophic cardiomyopathy and conduction defect was found after discharge. Cardiogenic shock should be considered, despite being a rare cause of shock in neonates.

• Clinical and Experimental Pediatrics
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• 제52권10호
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• pp.1175-1180
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• 2009

신생아 폐고혈압 지속증은 치료가 힘들고 사망률이 높은 질환이나, 산화질소 흡입 치료가 시행된 이후 사망률의 많은 감소를 가져왔다. 그러나, 신생아 집중 치료실이 있는 병원이라도 이러한 산화질소 흡입 치료가 가능하지 않는 곳이 많고, 산화질소 투여에도 호전되지 않는 경우도 있다. 흡입 iloprost는 최근 원발성 혹은 이차성 폐고혈압 환자에서 사용이 늘고있는 폐동맥 확장제로, 신생아 폐고혈압 지속증에 사용한 증례가 외국에 보고된 바 있다. 환아는 출생시 심한 태변 착색과 출산 질식, 진행되는 저산소증을 보였으며, 신생아 폐고혈압 지속증으로 진단되었다. 환아는 지속적인 저산소증을 보였으며, 통상적인 지지 치료에도 호전되지 않았다. 당시 저자들의 병원에는 산화질소 흡입 치료가 가능하지 않아, iloprost 흡입 치료를 시도하였다. Iloprost 흡입 치료 이후 수시간 내에 산소 포화도가 증가하였으며, 심초음파상에는 동맥관을 통한 우좌 단락이 좌우로 바뀌었고, 우심실 압력이 감소하였다. Iloprost 흡입 치료를 하는 동안 특별한 부작용은 관찰되지 않았다. 저자들은 산화질소 흡입치료가 가능하지 않은 상황에서 신생아 폐고혈압 지속증 신생아의 치료로 iloprost 흡입 치료를 시도한 경험을 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제45권11호
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• pp.1422-1425
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• 2002

저자들은 태아 곤란증 때문에 제왕절개한 과체중아로 저산소성 손상을 받은 태변 흡인 증후군 환아에서 생후 3-4일경에 어깨와 등에 여러 개의 홍반성의 결절과 반이 발생하였고 악화와 완화를 반복했으며 2-3회의 바늘 흡인(needle aspiration)을 시행하였고 합병증 없이 1세경 소실되었던 신생아 피하지방괴사 1례을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제53권2호
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• pp.244-247
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• 2010

자발성 종격동 기흉은 신생아기에 발생하는 호흡곤란의 드문 원인 중의 하나이며 대부분의 증례에서는 인공호흡, 출산손상, 태변흡입 등이 선행하는 경우가 많으며, 또한 대다수가 미숙아로 알려져있다. 저자들은 신생아 진찰 중 심음이 적게 들리는 소견으로 발견되었던, 위와 같은 위험인자가 없는 건강한 만삭아에서 발생한 자발성 종격동 기흉 1예를 경험하였기에 이를 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제50권1호
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• pp.85-88
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• 2007

모유 수유로 인한 고나트륨혈성 탈수는 흔하지는 않으나, 최근 모유 수유가 증가하면서 그 빈도가 증가할 수 있다. 고나트륨혈증은 여러 심각한 합병증을 초래할 수 있으므로 조기에 발견하여 치료해야 하며, 무엇보다 예방이 중요하다. 모유 수유로 인한 고나트륨혈성 탈수의 예방을 위해서는 모유 수유에 대한 올바른 교육과 퇴원 후 조기 추적 관찰이 중요하다. 저자들은 정상 신생아에서 아무런 합병증 없이 치료된 모유 수유로 인한 고나트륨혈성 탈수를 경험하였기에 이를 보고하는 바이다.