• 한국자원식물학회지
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• 제16권3호
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• pp.238-244
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• 2003

더덕 뿌리에서 유래한 EST 라이브러리로부터 dehydrin 유전자와 높은 상동성 을 나타내는 full clone cDNA를 얻었다. 더덕의 dehydrin, ClDhn1은 893 bp의 cDNA로 159개의 아미노산을 코딩하는 480 bp의 ORF를 가지고 있다. ClDhn1의 아미노산을 분석해 보면, 전체적으로 높은 친수성을 나타내며, lysine이 풍부한 K 반복구간(KIKEKLPG)을 카르보닐기 쪽에 2개 가지고 있다. 또한, 여러 dehydrin들의 공통적인 특징인 7개의 연속적인 serine잔기가 첫 번째 K반복 구간 앞에 위치한다. 그러나, 아미노기쪽의 DEYGNP보존 구간은 변형(DEHGNP)되어 있다. ClDhn1 유전자는 전사 단계에서 더덕의 뿌리에서 가장 높은 발현 양상을 보이며, 줄기와 잎에서는 적은 양이 발현되었다.

• 한국자동차공학회논문집
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• 제13권6호
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• pp.84-92
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• 2005

This paper is concerned with optimum design of a center-pillar assembly induced by the high-speed side impact of the vehicle. In order to simulate deformation behavior of the center-pillar assembly, simplified finite element model of the center-pillar and a moving deformable barrier are developed based on results of the crash analysis of a full vehicle model. In optimization of the deformation shape of the center-pillar, S-shaped deformation is targeted to guarantee reduction of the injury level of a driver dummy in the crash test. Tailor-welded blanks are adopted in the simplified center-pillar model to control the deformation shape of the center-pillar assembly. The thickness of each part which constitutes the simplified model is selected as a design parameter. The thickness of parts which have significant effect on the deformation mechanism are selected as design parameters with sensitivity analysis based on the design of experiment technique. The objective function is constructed so as to minimize the weight and lead to an S-mode deformation shape. The result shows that the simplified model can be utilized effectively for optimum design of the center-pillar members with remarkable saving of computing time.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제54권2호
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• pp.94-100
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• 2005

Korea Electrotechnology Research Institute(KERI) has successfully developed a 100hp-1800rpm-class high temperature superconducting(HTS) motor with high efficiency under partnership with Doosan Heavy Industries & Construction Co. Ltd. This motor has a HTS field winding and an air-cooled stator. The advantages of HTS motor can be represented by a reduction of 50% in both losses and size compared to conventional motors of the same rating. The cooling system is based on the heat transfer mechanism of the thermosyphon by using GM cryocooler as cooling source. The cold head is in contact with the condenser of a Ne-filled thermosyphon. Independently, the rotor assembly was tested at the stationary state and combined with stator. The HTS field winding could be cooled into below 30K. Test of open-circuit characteristics(OCC) and short-circuit characteristics(SCC) and load test with resistive load bank were conducted in generator mode. Also, load tests in motor mode driven by inverter were finished at KERI. Maximum operating current of field winding at 30K was 120A. From OCC and SCC test results synchronous inductance and synchronous reactance were 2.4mH, 0.49pu, respectively. Efficiency of this HTS machine was 93.3% in full load(100hp) test. This paper will present design, construction. and experimental test results of the 100hp HTS machine.

• Biomaterials and Biomechanics in Bioengineering
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• 제3권2호
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• pp.115-127
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• 2016

Shoulder pain, injury and discomfort are public health and economic issues world-wide. The function of these joints and the stresses developed during their movement is a major concern to the orthopedic surgeon to study precisely the injury mechanisms and thereby analyze the post-operative progress of the injury. Shoulder is one of the most critical joints in the human anatomy with maximum degrees of freedom. It mainly consists of the clavicle, scapula and humerus; the articulations linking them; and the muscles that move them. In order to understand the behavior of individual muscle during abduction arm movement, an attempt has been made to analyze the stresses developed in the shoulder muscles during abduction arm movement during the full range of motion by using the 3D FEM model. 3D scanning (ATOS III scanner) is used for the 3D shoulder joint cad model generation in CATIA V5. Muscles are added and then exported to the ANSYS APDL solver for stress analysis. Sensitivity Analysis is done for stress and strain behavior amongst different shoulder muscles; deltoid, supraspinatus, teres minor, infraspinatus, and subscapularies during adduction arm movement. During the individual deltoid muscle analysis, the von Mises stresses induced in deltoid muscle was maximum (4.2175 MPa) and in group muscle analysis it was (2.4127MPa) compared to other individual four rotor cuff muscles. The study confirmed that deltoid muscle is more sensitive muscle for the abduction arm movement during individual and group muscle analysis. The present work provides in depth information to the researchers and orthopedicians for the better understanding about the shoulder mechanism and the most stressed muscle during the abduction arm movement at different ROM. So during rehabilitation, the orthopedicians should focus on strengthening the deltoid muscles at earliest.

• International Journal of Automotive Technology
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• 제8권2호
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• pp.203-209
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• 2007

As the vehicle electronic control technology quickly grows and becomes more sophisticated, a more efficient means than the traditional in-vehicle driving test is required for the design, testing, and tuning of electronic control units (ECU). For this purpose, the hardware-in-the-loop simulation (HILS) scheme is very promising, since significant portions of actual driving test procedures can be replaced by HIL simulation. The HILS incorporates hardware components in the numerical simulation environment, and this yields results with better credibility than pure numerical simulations can offer. In this study, a HILS system has been developed for ESP (Electronic Stability Program) ECUs. The system consists of the hardware component, which that includes the hydraulic brake mechanism and an ESP ECU, the software component, which virtually implements vehicle dynamics with visualization, and the interface component, which links these two parts together. The validity of HIL simulation is largely contingent upon the accuracy of the vehicle model. To account for this, the HILS system in this research used the commercial software CarSim to generate a detailed full vehicle model, and its parameters were set by using design data, SPMD (Suspension Parameter Measurement Device) data, and data from actual vehicle tests. Using the developed HILS system, performance of a commercial ESP ECU was evaluated for a virtual vehicle under various driving conditions. This HILS system, with its reliability, will be used in various applications that include durability testing, benchmarking and comparison of commercial ECUs, and detection of fault and malfunction of ESP ECUs.

• The Korean Journal of Physiology and Pharmacology
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• 제8권1호
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• pp.27-31
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• 2004

${\Delta}^{12}-Prostaglandin$ $J_2\;({\Delta}^{12}-PGJ_2)$ is one of cyclopentenone prostaglandins. The ${\Delta}^{12}-PGJ_2$ is known to induce apoptosis of tumor cells, however, it's action mechanism is not clear. It has recently been reported that STAT3 is involved in tumorigenesis. In the present study, we investigated the role of STAT3-interacting protein (STIP1) in the cytotoxicity of ${\Delta}^{12}-PGJ_2$, since STIP1 was recently reported as a modulator of STAT3 activation by specifically binding to inactive (unphosphorylated) STAT3. The effect of ${\Delta}^{12}-PGJ_2$ was observed in stably overexpressing Neuro-2A cells transfected with full cDNA of STIP1, and cytotoxicity of ${\Delta}^{12}-PGJ_2$ in the transfected cells was increased, compared with the vector control cells. The cytotoxicity of ${\Delta}^{12}-PGJ_2$ treatment was significantly accentuated by pretreatment of the STIP1-transfected cells with protein kinase inhibitor, genistein, and less activation of STAT3 in STIP1-transfected cells was shown, compared with the vector control cells. Expression of bax was also increased in the STIP1-transfected cells. These data suggest that STIP1 inhibits cell growth via inhibition of STAT3 activation in ${\Delta}^{12}-PGJ_2$ treatment.

• 한국구조물진단유지관리공학회 논문집
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• 제6권1호
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• pp.95-102
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• 2002

The flexural behavior of the reinforced concrete (RC) structure upgraded by external reinforcements was examined in this study. It is well known that the incorporation of carbon fiber sheet (CFS) with concrete is one of the most effective ways to strengthen the RC structure. Complete bonding is required between CFS and concrete in order to make the RC structure provide its full function until the time the Re structures serve. Many studies have reported that construction deficiencies have caused the debonding of the CFS from concrete before the RC structure with CFS reaches its ultimate capacity. This research took a systematic look at the failure mechanism, macroscopic load-deformation characteristics, the maximum load applied, and maximum bending moment when construction deficiencies exist. The results of the experiment conducted were compared with theoretically derived values. In the future, the results of this investigation will help minimize the factors of construction deficiencies, which may occur when CFS is used to reinforce a RC structure. The experiment was manipulated with steel reinforcement ratio and piles of CFS on a total of 14 beams ($20cm{\times}30cm{\times}240cm$). The results showed that internal moment capacity increased even when construction deficiencies existed. However, RC structures with CFS in the field still contain a considerable level of potential risks.

• Archives of Plastic Surgery
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• 제36권5호
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• pp.571-577
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• 2009

Purpose: The Provision of thin and pliable tissue and the adequate coverage of tendon - gliding surface is necessary for a soft tissue defect of the hand with exposure of bone, tendon and muscle. This report will discuss our experience with anterolateral thigh fascial free flap for the reconstruction of the soft tissue defect of the hand. Methods: Between February 2004 and August 2008, seven patients with full - thickness soft tissue defects of the hand were reconstructed by means of a composite anterolateral thigh fascial free flap. There were soft tissue defects associated with trauma (n=5), scar contracture (n=1) and necrosis due to ischemia (n=1). Flaps were harvested from the anterolateral thigh as adipofascial flaps with only a small sheet of fascia and fatty tissue above it. The fascia and the skin of the donor site was closed directly and delayed split - thickness skin graft was performed. Result: All flaps survived completely. The size of the transferred flap ranged from $2{\times}4cm$ to $5{\times}8cm$. Thin flap coverage was possible without secondary debulking operations. It left minimal donor site morbidity with a linear scar. In one case, the thigh muscle herniation in the donor site was developed. Conclusion: The anterolateral thigh fascial free flap provided thin and pliable tissue which can establish a tendon - gliding mechanism, minimal bulk, minimal donor site morbidity. The disadvantages of this technique were the need for a skin graft and the muscle herniation of donor site.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.109-109
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• 2010

$Er^{3+}$ ion shows a stable and efficient luminescence at 1.54mm due to its $^4I_{13/2}\;{\rightarrow}\;^4I_{15/2}$ intra-4f transition. As this corresponds to the low-loss window of silica-based optical fibers, Er-based light sources have become a mainstay of the long-distance telecom. In most telecom applications, $Er^{3+}$ ions are excited via resonant optical pumping. However, if nanocluster-Si (nc-Si) are co-doped with $Er^{3+}$, $Er^{3+}$ can be excited via energy transfer from excited electrical carriers in the nc-Si as well. This combines the broad, strong absorption band of nc-Si with narrow, stable emission spectra of $Er^{3+}$ to allow top-pumping with off-resonant, low-cost broadband light sources as well as electrical pumping. A widely used method to achieve nc-Si sensitization of $Er^{3+}$ is high-temperature annealing of Er-doped, non-stoichiometric amorphous thin film with excess Si (e.g.,silicon-rich silicon oxide(SRSO)) to precipitate nc-Si and optically activate $Er^{3+}$ at the same time. Unfortunately, such precipitation and growth of nc-Si into Er-doped oxide matrix can lead to $Er^{3+}$ clustering away from nc-Si at anneal temperatures much lower than ${\sim}1000^{\circ}C$ that is necessary for full optical activation of $Er^{3+}$ in $SiO_2$. Recently, silicon-rich silicon nitride (SRSN) was reported to be a promising alternative to SRSO that can overcome this problem of Er clustering. But as nc-Si formation and optical activation $Er^{3+}$ remain linked in Er-doped SRSN, it is not clear which mechanism is responsible for the observed improvement. In this paper, we report on investigating the effect of separating the nc-Si formation and $Er^{3+}$ activation by using hetero-multilayers that consist of nm-thin SRSO or SRSN sensitizing layers with Er-doped $SiO_2$ or $Si_3N_4$ luminescing layers.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.288-288
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• 2013

Lithium-ion battery (LIB) is one of the most important rechargeable battery and portable energy storage for the electric digital devices. In particular, study about the higher energy capacity and longer cycle life is intensively studied because of applications in mobile electronics and electric vehicles. Generally, the LIB's capacity can be improved by replacing anode materials with high capacitance. The graphite, common anode materials, has a good cyclability but shows limitations of capacity (~374 mAh/g). On the contrary, silicon (Si) and germanium(Ge), which is same group elements, are promising candidate for high-performance LIB electrodes because it has a higher theoretical specific capacity. (Si:4200 mAh/g, Ge:1600 mAh/g) However, it is well known that Si volume change by 400% upon full lithiation (lithium insertion into Si), which result in a mechanical pulverization and poor capacity retention during cycling. Therefore, variety of nanostructure group IV elements, including nanoparticles, nanowires, and hollow nanospheres, can be promising solution about the critical issues associated with the large volume change. However, the fundamental research about correlation between the composition and structure for LIB anode is not studied yet. Herein, we successfully synthesized various structure of nanowire such as Si-Ge, Ge-Carbon and Si-graphene core-shell types and analyzed the properties of LIB. Nanowires (NWs) were grown on stainless steel substrates using Au catalyst via VLS (Vapor Liquid Solid) mechanism. And, core-shell NWs were grown by VS (Vapor-Solid) process on the surface of NWs. In order to characterize it, we used FE-SEM, HR-TEM, and Raman spectroscopy. We measured battery property of various nanostructures for checking the capacity and cyclability by cell-tester.