• 분석과학
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• 제8권4호
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• pp.449-456
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• 1995

Novel macrocyclic ligands modified with pendant arms, N, N', N'', N''', N'''', N'''''-hexakis(2-aminoethyl)-1, 4, 7, 10, 13, 16-hexaazacyclootadecane [$L_3$, Fig.1] and 1, 4, 7-tris(3-(o-hydroxyphenyl)propyl)-1, 4, 7-triazacyclononane [$L_4$, Fig.1] have been synthesized, and the protonation of $L_3$ and $L_4$ and stability constants of $L_3$ with bivalent transition metal ions and rare earth metal ions were determined by a potentiometry. The obtained results show that the complex formation of $L_3$ depends on the metal ligand ratios, and the stability of the metal complexes does not depend on the sizes of the metal ions, but on the nature of the metal ions. The structures of the rare earth complexes for $L_4$ were characterized by an X-ray absorption spectrometry(XAFS).

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제39권6호
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• pp.289-291
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• 2013

Moyamoya disease is a rare neurovascular disorder that involves constriction of certain arteries in the brain. In patients with moyamoya disease, it is very important to prevent cerebral ischemic attacks and intracerebral bleeding caused by fluctuating blood pressure and increased respiration. A 40-year-old woman with moyamoya disease was scheduled for extraction of her right upper and lower impacted wisdom teeth. Her lower impacted wisdom tooth was situated close to the inferior alveolar nerve. We decided to continue her oral antiplatelet therapy and planned intravenous sedation with analgesic agents administered approximately five minutes prior to extraction of the root of the mandibular wisdom tooth. Oral analgesic medications were regularly administered postoperatively to alleviate pain and anxiety. During the perioperative period, no cerebrovascular event occurred, and the wisdom teeth were successfully extracted as per the planned procedure. It is thought that the perioperative risks of wisdom tooth extraction in patients with moyamoya disease can be minimized with the use of our protocols.

• Environmental Analysis Health and Toxicology
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• 제23권4호
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• pp.307-314
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• 2008

폐기물 매립지의 조기 안전화를 위해 여러 가지 Chemical Oxidation법이 개발되어 왔지만, 이 방법을 폐기물 매립지에 적용하고 난 후에 생성될 수 있는 부산물들이 주변 환경에 영향을 줄 가능성이 있다. 그래서, 이 방법을 실제 매립지에 적용하기 전에, 일본 키타큐슈에 있는 소각재가 묻혀 있는 모형 매립지에 다섯 가지 조건 -A, 콤포스트 추가; B, 과산화수소수 살수; 과산화수소수+공기주입; D, 공기주입; E, control- 을 적용하여 그 효능을 테스트하였고, 이 매립지에서 이 방법들의 적용 후에 생성되는 침출수의 급성 독성을 세 가지 microbiotests를 이용하여 monitoring하였다. 테스트 기간 중, 침출수의 수질은 개선되었고, 그 급성 독성은 점차적으로 감소하였다. 과산화수소수와 공기의 조합을 적용한 후 생성된 침출수의 급성 독성이 가장 빨리 감소하여 폐기물 매립지의 조기 안정화에 도움을 주었다. 이러한 독성 시험 결과는 몇 가지 화학적 parameters와 상관성이 있었고 여기에 사용된 급성 독성 테스트법은, 매립지 안정화를 위한 Chemical Oxidation법의 적용 후, 침출수 수질을 monitoring하는데 적절하였다. 그러므로 폐기물 매립지의 조기 폐지 기준에 독성 시험의 포함을 고려해 볼 필요가 있다고 생각한다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권4호
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• pp.323-327
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• 2017

QT prolongation is an electrocardiographic change that can lead to lethal arrhythmia. Acquired QT prolongation is known to be caused by drugs and electrolyte abnormalities. We report three cases in which the prolonged QT interval was improved at the time of operation by briefly discontinuing the drugs suspected to have caused the QT prolongation observed on preoperative electrocardiography. The QTc of cases 1, 2, and 3 improved from 518 to 429 ms, 463 to 441 ms, and 473 to 443 ms on discontinuing the use of a gastrointestinal prokinetic agent, a proton pump inhibitor, and a molecular targeted drug, respectively. These cases were considered to have drug-induced QT prolongation. We reaffirmed that even drugs administered for conditions unrelated to cardiac diseases can have adverse side effect of QT prolongation. In conclusion, our cases indicate that dental surgeons should be aware of the dangerous and even potentially lethal side effects of QT prolongation. For safe oral and maxillofacial surgery, cooperation with medical departments in various fields is important.

• World Technopolis Review
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• 제7권2호
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• pp.125-134
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• 2018

The purpose of this article is to introduce and describe the case of Fukuoka Next-generation Social System Creation Hub based on the conceptual framework of regional innovation platform strategy. In short, it is a "government-issued" regional innovation platform strategy to improve innovativeness with limited creative capital through "borrowing" not money but network, wisdom, know-how, and ideas from each other between some stakeholder groups in a region. The Fukuoka Industry, Science & Technology Foundation, which is the coordinating institution of the whole program, plays the role of a platformer to unify various projects into the program crossing borders between stakeholder groups for building regional innovation platforms that lends intensive support to feedback loops between the program facilitator and its partners in the program. Thanks to being a government-issued one, it could be tied together with some wide ranging issues of policy on social innovations, such as the "low carbon society" or the "health and longevity society." But at the same time, it is a concern that many regional research institutions that have innovative potential and diverse ideas become governed by the platform without their noticing it and dealt with in the same way based on "selected" and "designated" strategic goals. Therefore, it seems that a regional innovation platform strategy is a kind of "double-edged sword" in public policy in the era of "panopticism of bureaucratic society" in Japan.

• 드라이브 ㆍ 컨트롤
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• 제18권4호
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• pp.72-76
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• 2021

The aim of this study was to establish a breathing assist system for saxophone players with breathing problems. Although the saxophone is a popular wind instrument with a reed in its mouthpiece, it can be difficult for people with breathing problems to play this instrument, as it requires adequate breath support for deep and even long breaths. To solve this problem, the authors propose a breathing assist device, which functions like a pneumatic master-slave amplifier, for saxophone players with breathing problems. First, the proposed device is fabricated. Second, the effectiveness of the breathing assist device as a master-slave amplifier is confirmed through experiments. Third, the dynamic characteristics of the device are tested up to 10 Hz, and they demonstrate that the device responds well for up to approximately 5 Hz.

• 한국지진공학회논문집
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• 제10권4호
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• pp.45-54
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• 2006

2005년 3월 20일 발생한 Fukuoka 지진 시 국내 및 일본에서 관측된 자료를 이용하여 지반운동 감쇄특성을 분석하였다. 또한 최근 국내 및 일본에서 제시된 지반운동 거리감쇄식을 이용한 예측값과의 비교를 통하여 국내 강지진동 예측 시 일본에서 개발된 감쇄식의 적용가능성을 평가하였다. 그 결과 동일 거리에 위치한 국내 및 일본 관측소에서 측정한 기록이 비교적 유사하게 나타났으며 국내 및 일본에서 제시된 지반운동 거리감쇄식의 예측값이 매우 유사하게 나타나 국내에서의 강지진동 예측 시 일본에서 제시된 지반운동 감쇄식을 200km 이상의 비교적 원거리에 대한 국내 감쇄식의 평가 등에 유용하게 활용할 수 있는 것으로 나타났다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3377-3380
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• 2016

The proportion of lung cancer patients under 50 years old is small at approximately 5-10%, but as with patients older than 50, the number is on the rise. Although lung cancer treatment strategies have undergone extensive transformation in recent years based on the presence or absence of oncogenic driver mutations, there are few reports regarding these mutations in the young or the relationship between clinical setting and prognosis. Therefore, we conducted a study of clinical features in 36 patients under the age of 50 who were diagnosed with primary lung cancer from October 2008 to November 2015. The 22 patients in stages I through III A underwent operations, and all 17 whose lung cancer were detected through screening were candidates for surgery. Gene analysis was conducted for 26 (72.2%); 10 (38.5%) were positive for EGFR gene mutations, and ALK gene translocation was present in 4 (15.4%). In stage IV patients, the median progression free survival (PFS) in the ALK translocation positive and negative patients was 518 days and 130 days, respectively, and the median overall survival (OS) was not reached and 280 days, respectively. A trend toward extended PFS (p=0.203) and OS (p=0.056) was observed in patients positive for ALK translocation. We must strive for early detection by increasing screening rates and evaluate oncogenic driver mutations important for prognosis of lung cancer in the young.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1993년도 한국자동제어학술회의논문집(국제학술편); Seoul National University, Seoul; 20-22 Oct. 1993
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• pp.54-59
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• 1993

This paper presents a method of estimating 3-D surface geometrical features that are necessary for 3-D object recognition and image interpretation. The features, such as surface needle maps and curvatures, are computed from range or intensity images. In general, the range and intensity images are prone to noises, and hence the features computed by differentiation calculi on such a noisy image are hardly applicable to industrial recognition tasks. In our approach, we try to obtain a more accurate estimate of the features by using a least-squares minimization procedure subject to local curvature consistency constraints. The algorithm is robust with respect to noises and is completely independent of the viewpoint at which the image is taken. The performance of the ajgoritlim is evaluated using both synthetic data and real intensity images.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2004년도 Proceedings of ISRS 2004
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• pp.541-544
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• 2004

Recently, the heat island phenomenon in which the temperature of a city part rises from the circumference ground has developed into a big problem. In this study, we aimed at examining the impact of increasing vegetation in urban areas to reduce the heat island phenomenon by taking the Fukuoka City of Japan as a case. In order to discuss the relation between vegetation environment and the heat island phenomenon, we have calculated Normalized Difference Vegetation Index (NDVI) and mapped the spatial vegetation distribution. These are then compared with the heat island phenomenon investigations in Fukuoka City. The results of the study revealed that the areas showing comparatively lesser heat island phenomenon are those having increased vegetation.