• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.2163-2166
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• 2004

For designing high Tc superconductor proceeding bearing(HTSJB) which is used on a flywheel energy storage system which requests the free of the bearing loss caused by the friction, it is necessary to understand the basic characteristics of the classical superconductor proceeding bearing because the mechanical characteristics of the HTSJB are identified by the magnetic relationships between the permanent magnet(PM) and the high Tc superconductor(HTS). In this paper, using the method, frozen image model, the force problems between the PM and the HTS were solved and then the dynamic characteristics of the rotor inside of the HTSJB can be expected in advance by using the basic characteristics between the PM and the HTS. The coefficient of friction of the HTSJB was measured in the vacuum environment. From the results, the mechanical characteristics of HTSJB can be identified using the numerical models.

• Progress in Superconductivity
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• 제5권2호
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• pp.141-143
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• 2004

For designing a flywheel system using superconductor, it is necessary to understand the basic characteristics of the classical superconductor bearing. It is difficult to expect the characteristics of superconductor bearings using models that have been introduced up to now. In the "Frozen image" concept, the farce between the permanent magnet and the superconductor can be divided into two forces between permanent magnet and two imaginary magnets in the superconductor; one represents attraction farce and the other represents a repulsion force. We calculated the characteristics of two superconductor bearings, such as an axial, the radial stiffness and the levitation force. This calculation method was very helpful to expect the characteristics of the superconductor bearings. Using this model, we established the optimum condition for the superconductor bearing.r bearing.

• 대한방사성의약품학회지
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• 제9권1호
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• pp.17-21
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• 2023

In this study, we evaluated the targeting of prostate cancer (PCa) using [¹⁸F]Florastamin in non-clinical study, for the purpose of therapeutic monitoring of [¹⁷⁷Lu]Ludotadipep, a therapeutic radiopharmaceutical for PCa, [¹⁸F]Florastamin/[¹⁷⁷Lu]Ludotadipep was co-administered to a single-individual prostate tumor bearing mouse model, mimicking clinical condition. Considering the difference in half-life of the two isotopes (¹⁸F or ¹⁷⁷Lu), image scan of whole-body autoradiography was performed at 24 or 48 h after preparation of frozen section, respectively. Then, it was confirmed whether they showed the same targeting efficiency for the area of tumor. A tumor xenograft model was prepared using PSMA-overexpressing PC3-PIP prostate cancer cells. [¹⁸F]Florastamin [111 MBq (3 mCi) in 100 µL]/¹⁷⁷Lu]Ludotadipep [3.7 MBq (100 µCi) in 100 µL] was co-administered through the tail vein, and 2 hours after administration, the mice were frozen, and after freezing for 24 hours, whole-body cryosection was performed at 24 h after freezing. Image scanning using cryosection was performed after 24 or 48 hours after freezing, respectively. In the scan image after 24 hours, tumor uptake of [¹⁸F] Florastamin/[¹⁷⁷Lu]Ludotadipep were simultaneously observed specific uptake in the tumor. In the scan image after 48 hours in the same section, signal of ¹⁸F was lost by decay of radioisotope, and specific uptake image for [¹⁷⁷Lu]Ludotadipep was observed in the tumor. Uptake of [¹⁷⁷Lu]Ludotadipep was specific to the same tumor region where [¹⁸F]Florastamin/[¹⁷⁷Lu]Ludotadipep was uptake. These results suggested that [¹⁸F]Florastamin showed the same tumor uptake efficiency to PCa as [¹⁷⁷Lu]Ludotadipep, and effective therapeutic monitoring is expected to be enable using [¹⁸F]Florastamin during [¹⁷⁷Lu]Ludotadipep therapy for PCa.

• 한국전자통신학회논문지
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• 제17권3호
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• pp.483-490
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• 2022

말라리아는 기생충에 의해 발생하는 질병으로 전 세계에 퍼져있다. 말라리아 셀을 인식하는데 일반적으로 두꺼운 혈흔과 얇은 혈흔 검사 방법이 사용되지만 이러한 방법은 많은 수작업 계산이 필요하여 효율성과 정확성이 매우 낮을 뿐만 아니라 빈민국에는 병리학자가 부족하여 말라리아 치명율이 높다. 본 논문에서는 특징 추출기, 잔류 구조와 완전 연결층으로 구성되고, 전이 학습을 이용한 말라리아셀 이미지를 인식하는 모델을 제안한다. VGG-19 모델의 사전 학습된 파라미터가 사용될 때 일부 컨볼루션층의 파라미터는 고정되고, 모델의 데이터에 맞추기 위하여 미세조정이 사용된다. 그리고 제안된 모델과 비교하기 위하여 잔류 구조가 없는 말라리아셀 인식 모델을 구현한다. 실험 결과 잔류 구조를 사용한 모델이 잔류 구조가 없는 모델에 비하여 성능이 우수 하였으며, 최신 논문과 비교하여 가장 높은 97.33%의 정확도를 보여주었다.

• 한국멀티미디어학회논문지
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• 제22권6호
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• pp.729-737
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• 2019

This study defined the animation space as the concept of map based on the space of Joseph Campbell's heroic narrative. The space in which the animated character exists is an image symbolic language that reflects the inner and outer growth stages of the hero. I focused on the spatiality that plays the role of the power to lead the narrative and examined the meaning as the mediator that leads the heroic narrative. First, 6 spatial variables were derived by observing 'Hero's Journey 'which is used as a basis of US commercial animation scenario. Second, spatial variables are defined as 64 zones and proposed as 'Spatial Map Model of the Hero's Journey' (SMMH). Third, the character space of was applied to 'SMMH', and the change of space utilization rate and spatiality and the narrative meaning were analyzed. This study extended the narrative of animation space which was not actively studied to map concept. It is possible to provide a different viewpoint in animation production and research.

• 한국초전도저온공학회:학술대회논문집
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• 한국초전도저온공학회 2003년도 추계학술대회 논문집
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• pp.240-242
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• 2003

The properties of superconductor bearing are depend on shape of rotor, especially thickness of ferromagnetic shim between permanent magnets. The levitation forces and stiffness of superconductor bearings as the thickness of the ferromagnetic shim were calculated and measured, Frozen image model and difference of magnetization per unit volume of the superconductor were used to calculate stiffness for two models. The calculated values had similar trend with the measured one. From the results, an optimal design of the rotor was selected.

• 대한수의학회지
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• 제38권4호
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• pp.882-897
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• 1998

This experiment was conducted to predict the effects of motional characteristics on the fertility of Korean native cattle(KNC) by using CASA technology and in vitro fertilization system. Twenty-six KNC frozen semen straws were obtained from Korean KNC improvement department, livestock improvement main division, national livestock cooperatives federation in Korea. Specimens were allowed to thaw at $37^{\circ}C$ for 30 sec in water bath. Semen analysis was performed on semen image analysis system(SIAS, Medical supply, Korea) adjusted to the gate settings and used the semen droplet ($5{\mu}l$) placed on Makler counting chamber(Sefi medical instrument, Israel) prewarmed at $37^{\circ}C$. The same person used the same micropipette to fill the Makler counting chamber. A total of 150 or more of sperms were analysed in each specimen by a single trained person by scanning at least 5 to 10 fields. The oocytes collection, in vitro maturation, IVF, in vitro culture and determination of the cleavage rate were performed by the technique, as described by Hwang et al (1997). Statistical analysis was done by linear regression with use of the Sigma plot program on a IBM personal computer. The cleavage rate in vitro fertilized oocyte was significantly correlated(P<0.05) with MOT, VCL, VSL, VAP, ALH, BCF and MAD, but not CON, LIN, STR, WOB, DNM, DNC and HYP in regressional analysis. The results show that some kinematic characteristics of frozen-thawed semen by CASA can be predict the fertility in in vitro model system.

• 한국임상수의학회지
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• 제27권3호
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• pp.216-219
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• 2010

본 연구의 목적은 개 피부장벽 손상모델을 실험적으로 구현하기 위해 개의 정상피부, 제모 된 피부 그리고 아세톤 및 테잎 스트리립핑에 의한 손상된 피부에서의 표피내 칼슘이온의 분포를 관찰하였다. 피부손상에 따른 표피의 칼슘이온 변화도는 화학적 표시자(Calcium Green-1)가 포함된 gel blotting을 적용하여 피부장벽손상 효과를 시간에 따라 형광현미경으로 관찰하였다. 아세톤 손상 후 3분 및 1시간에 표피와 모낭의 칼슘이온의 차이를 나타내는 형광도차는 보다 밝게 관찰된 후 48시간 후에 소실되었다. 이와는 대조적으로, 테잎스트립핑손상 후 3분 및 1시간의 표피 칼슘이온의 형광도차는 아세톤 손상에서보다 더 밝게 보였다가 48시간 후에 소실되었다. 본 실험상의 방법을 통해 피부 손상 방법에 따른 표피 칼슘이온의 가시적 이미지를 관찰할 수 있었고, 표피내 농도차이를 확인할 수 있었다. 따라서 본 화학표시자를 이용한 염색법은 개 피부장벽 복구기전에 대한 칼슘이온의 역할을 규명하는데 유용할 것으로 판단되며, 추후 표피칼슘이온 농도의 정량분석법에 관한 연구가 필요할 것으로 사료된다.

• 대한핵의학회지
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• 제30권4호
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• pp.484-492
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• 1996

허혈성 뇌 병변에서 $^{99m}Tc$-glucarate의 섭취에 관한 연구를 하기 위하여 중뇌동맥 폐쇄 쥐 뇌허혈 모델을 재관류한 군과 하지 않은 군으로 나누어 만들었다. $^{99m}Tc$-glucarate와 [$^{18}F$]FDG를 연속적으로 투여하여 그 분포 양상을 이중 자가방사촬영법으로 관찰하였다. 조직의 괴사 여부를 알기 위하여 TTC 염색도 실시하여 동일한 뇌표본에 대하여 3가지의 영상을 동시에 얻을 수가 있었다. 얻은 영상으로 섭취 또는 비섭취정도를 보아 0점에서 3점까지 점수를 매겨 합하여 비교하였다. 수술한 쥐들 18마리 중 10마리가 신경학적 증상을 보이면서 살아남아 실험대상이 되었다. TTC 염색으로 확인한 경색크기는 재관류하지 않은 군이 컸다. [$^{18}F$]FDG 섭취양상은 TTC 염색과 거의 비슷하였다. 다만 일부에서 TTC 염색되는 곳에 [$^{18}F$]FDG 가 중간정도로 섭취되는 곳이 있었고 TTC 염색되지 않는 곳에 [$^{18}F$]FDG가 중간정도 섭취되는 곳이 있었다. TTC로 염색된 부위에는 $^{99m}Tc$-glucarate가 섭취되지 않았다. TTC로 염색되지 않는 곳에 일부분 $^{99m}Tc$-glucarate가 섭취되었다. TTC와 [$^{18}F$]FDG가 염색되거나 섭취되지 않는 곳에 $^{99m}Tc$-glucarate가 섭취되지 않는 곳이 있었다. 그러나 [$^{18}F$]FDG의 중간 정도의 섭취나 [$^{18}F$]FDG와 TTC사이에 부합하지 않는 곳 등과 $^{99m}Tc$-glucarate 섭취와 대응시키기 어려웠다 $^{99m}Tc$-glucarate가 재관류 군에서 더 넓고 많이 섭취되었다. 결론적으로 $^{99m}Tc$-glucarate는 비생존 허혈조직에만 섭취되는데 관류재개통에 따라 다양하게 섭취되었고 재관류모델에 더 많이 넓게 섭취되었다. 중뇌동맥폐색 및 재관류 모델로 $^{99m}Tc,\;^{18}F$ 및 TTC 동시영상을 얻어 생존능과 포도당대사의 부합 비부합 여부를 밝히고 그 의의를 조사한 후 $^{99m}Tc$-glucarate섭취와 상관을 조사하면 $^{99m}Tc$-glucarate섭취의 의의를 밝힐 수 있을 것으로 본다.