• Maxillofacial Plastic and Reconstructive Surgery
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• 제40권
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• pp.40.1-40.8
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• 2018

Background: A 9-year-old male showed severe defects in midface structures, which resulted in maxillary hypoplasia, ocular hypertelorism, relative mandibular prognathism, and syndactyly. He had been diagnosed as having Apert syndrome and received a surgery of frontal calvaria distraction osteotomy to treat the steep forehead at 6 months old, and a surgery of digital separation to treat severe syndactyly of both hands at 6 years old. Nevertheless, he still showed a turribrachycephalic cranial profile with proptosis, a horizontal groove above supraorbital ridge, and a short nose with bulbous tip. Methods: Fundamental aberrant growth may be associated with the cranial base structure in radiological observation. Results: The Apert syndrome patient had a shorter and thinner nasal septum in panthomogram, PA view, and Waters' view; shorter zygomatico-maxillary width (83.5 mm) in Waters' view; shorter length between the sella and nasion (63.7 mm) on cephalogram; and bigger zygomatic axis angle of the cranial base (118.2°) in basal cranial view than a normal 9-year-old male (94.8 mm, 72.5 mm, 98.1°, respectively). On the other hand, the Apert syndrome patient showed interdigitating calcification of coronal suture similar to that of a normal 30-year-old male in a skull PA view. Conclusion: Taken together, the Apert syndrome patient, 9 years old, showed retarded growth of the anterior cranial base affecting severe midface hypoplasia, which resulted in a hypoplastic nasal septum axis, retruded zygomatic axes, and retarded growth of the maxilla and palate even after frontal calvaria distraction osteotomy 8 years ago. Therefore, it was suggested that the severe midface hypoplasia and dysostotic facial profile of the present Apert syndrome case are closely relevant to the aberrant growth of the anterior cranial base supporting the whole oro-facial and forebrain development.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제41권
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• pp.48.1-48.7
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• 2019

Background: Soft tissue asymmetry such as lip canting or deviation of the philtrum is an important influencing factor for unbalanced facial appearance. Lip canting could be improved by the correction of the occlusal canting or positional change of the mentum. Although there are many studies about changes of lip canting, however, postoperative changes of philtrum deviation have not been yet reported. In this study, we investigate the positional change of the philtrum after orthognathic surgery and influencing factors. Methods: Positional change of the philtrum was evaluated in 41 patients with facial asymmetry who underwent bimaxillary surgery, in relation to other anatomical soft tissue landmarks using a frontal clinical photo. The surgical movement of the maxillary and mandibular dental midline and canting were measured in postero-anterior cephalogram before and 1 day after surgery. The same procedure was repeated in patients with more than 1.5 mm perioperative change of the mandibular dental midline after bimaxillary surgery. Results: Maxillary dental midline shifting and canting correction did not have a significant correlation with lateral movement of the philtrum midline. However, the mandibular shift had a statistically significant correlation with a lateral movement of the philtrum (p < 0.05) as well as other linear parameters and angle values. Conclusion: The horizontal change of the philtrum is influenced by lateral mandibular movement in patients with facial asymmetry, rather than maxillary lateral movement.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권4호
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• pp.337-345
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• 2011

Purpose: The purpose of this study was to define the relation of the degree of menton deviation and 3-D CT (computerized tomography) measurements of the glenoid fossa and the mandible, which are considered to have an influence on menton deviation. Methods: The CT images were obtained in 60 adults and these were transmitted to a computer and reconstructed using computer software. According to the degree of the menton deviation, which was measured on the posteroanterior cephalogram, the subjects were divided into the menton deviated group (30 adults) and the symmetry group (30 adults). A total of 11 measurements that might have an effect on menton deviation were determined and these were measured in the right and left sides using the function of 3-D measurement in the computer program. The 11 measurements consist of 6 measurements in the glenoid fossa (vertical position of the glenoid fossa and articular eminence, the sagittal position of the glenoid fossa and articular eminence, the depth of the glenoid fossa, and the anterior angle of the glenoid fossa), and 5 measurements in the mandible (ramus length, frontal ramal inclination, lateral ramal inclination, body length, body height). Results: The comparison of the differences between the menton deviated and symmetry groups and correlation analysis on the degree of menton deviation were carried out. The results of comparison of the right and the left difference between the menton deviated and symmetry groups showed that the vertical position and depth of the glenoid fossa were significantly increased in the menton deviated group. Conclusion: The results of the present study show that consideration of the shape and position of the glenoid fossa is necessary for making the diagnosis and administering proper treatment in facial asymmetry patients and especially growing patients.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권4호
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• pp.594-606
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• 1996

저자는 하악골의 측방 변위를 보이는 악안면 비대칭증례에서 이하두정방사선규격사진과 정모두부방사선규격사진을 이용하여 두개부 형태와 악안면부의 비대칭성과의 상호 관련성을 조사하여 다음과 같은 결론을 얻었다. 1. 이하두정방사선규격사진에서 하악골의 편위정도는 평균 $-3.12{\pm}3.80$ 이며 절대치의 평균은 $2.50{\pm}2.82$ 이였다. 2. 이하두정방사선규격사진에서 비편위측과 편위측에 대한 유의성 검정에서 통계적인 유의성은 없었으나(p>0.05), 그 차이의 평균은 전두부(Y10, Y9, Y8, Y7, Y6)에서는 편위측이 상대적으로 더 크고, 측두부(Y5, Y-1, Y-2, Y-3, Y-4, Y-5, Y-6)에서는 비편위측이 상대적으로 더 크게 나타났다. 3. 정모두부방사선규격사진에서 술전의 하악골의 평균 편위는 $1.3983{\pm}3.521$ 이며 절대치의 평균은 $3.95{\pm}2.85$ 이였다. 4. 정모두부방사선규격사진에서 수술에 의한 변화량 (PT2A-PT1A) 에 대한 재발량(PTLA-PT2A)의 상관관계분석에서 수술에 의한 이동량이 많을 수록 재발이 많은 것으로 나타났다(p<0.05). 5. 이하두정방사선규격사진에서 하악골 편위정도에 대하여 두개관 형태(비변위-변위차이)에 대한 상관관계분석에서 통계적인 유의성은 없었으나(P>0.05), 변위가 클수록 전두부에서는 비변위측이, 후두부에서는 변위측이 더 큰 경향을 보였다. 6. 정모두부방사선사진상에서 하악골의 변위 정도에 대한 두개관(비변위-변위)과의 상관관계 분석에서 Y4(P<0.05), Y3, Y2, Yl, 0, Y-1, Y-2, Y-4, Y-6(P<0,01), Y-5(p<0.001) 등의 위치에서 하악골의 변위 정도가 클수록 비변위측이 더 큰 것으로 나타났다. 7. 정모두부방사선사진상에서 하악골 재발에 대한 두개관(비변위-변위)과의 상관관계분석에서는 통계적인 유의성이 없었으나(P>0.05), 측두부에서는 비변위-변위 차이가 클수록 재발이 많은 경향을 보였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권3호
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• pp.214-220
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• 2001

안면비대칭이나 반안면왜소증과 같은 구강악안면영역의 기형에 대한 진단 및 치료 계획 수립을 위하여 두개 악안면 구조물에 대한 총체적인 접근이 필요하다. 이에 두부 규격 방사선 사진을 이용한 3차원 두부 계측 방사선 시스템의 임상적 적용이 계속 시도되었으나 주로 두 방향의 방사선원으로부터 동시에 얻어진 standard Broadbent-Bolton cephalometer에 한정되어 있었다. 이에 본 연구에서는 단일방사선원에 의하여 촬영된 한 쌍의 정모 및 측모두부방사선 사진으로 정확한 3차원 좌표치를 얻을 수 있는 방법을 개발하고 이렇게 얻어진 3차원 좌표치의 정확도와 재현성을 검증하여 다음과 같은 결과를 얻었다. 1. 정모, 측모 두부 방사선 사진을 동시에 촬영하지 않음으로 인하여 생기는 오차를 보정해주는 수학적인 공식을 산출하고 이 공식에 의거하여 정모 두부 방사선 사진에 기준한 측모 두부 방사선 계측 사진의 위치 결정시의 오차를 건조 두개골을 이용하여 검증한 결과 1차와 2차 측정시 각각 평균 $0.46{\pm}1.21^{\circ}, $0.33{\pm}0.90^{\circ}로 나타났다. 2. 단일 방사선원으로부터 3차원 계측점의 좌표값을 얻을때의 재현성을 파악하기 위한 임상적 계측 결과 1, 2차측정간의 오차가 절대값 평균 0.54mm ($-2.99{\sim}2.26mm$)로 나타났으며 이때 계측점 인식의 오차는 평균 $1.2{\pm}1.6mm$ 였다. 위와 같은 결과를 종합하여 볼 때 정모 두부 방사선 사진에 의거한 측모 두부 방사선 계측사진의 위치를 결정한 후 두부위치 보정공식을 도입하면 임상적으로 충분히 재현성 있는 3차원 계측을 할 수 있다는 것을 알 수 있었다.을 증가시킨다. - PKC pathway는 MAPK pathway를 경유하여 Runx2의 전사 활성을 조절한다.있을 것으로 사료된다.대구치의 원심경사는 필연적으로 일어나며, 이를 최소화하기 위한 노력이 계속되어야 할 것으로 사료된다.글래스 아이오노머 시멘트 사이에는 유의한 차이가 없었다.착제의 종류에 따른 전단결합강도를 비교한 결과, 영구치와 유치 모두에서 Clearfil SE Bond를 사용한 군의 전단결합강도가 가장 높았으며 AQ Bond를 사용한 군의 전단결합강도가 가장 낮았다.본에서 III군에 비해 크기가 큰 기포가 더욱 많이 관찰되었다.e의 약동학은 cimetidine에 의해 유의한 차이를 보였으며 CYP1A2유전자형에 따른 영향은 관찰할 수 없었다. CYP1A2유전자형에 따른 생체내 대사능을 관찰하는 실험이 향후 이루어 져야 할 것으로 사료된다.san film보다 큰 수증기 투과도를 보였다.적으로 유의한 차이를 보이지 않았다.y tissue layer thinning은 3 군모두에서 관찰되었고 항암 3 일군이 가장 심하게 나타났다. 이상의 실험결과를 보면 술전 항암제투여가 초기에 시행한 경우에는 조직의 치유에 초기 5 일정도까지는 영향을 미치나 7 일이 지나면 정상범주로 회복함을 알수 있었고 실험결과 항암제 투여후 3 일째 피판 형성한 군에서 피판치유가 늦어진 것으로 관찰되어 인체에서 항암 투여후 수술시기는 인체면역계가 회복하는 시기를 3주이상 경과후 적어도 4주째 수술시기를 정하는 것이 유리하리라 생각되었다.한 복합레진은 개발의 초기단계이며, 물성의 증가를 위한 연구가 필요할 것으로 사료된다.또 다른 약물인 glycyrrhetinic acid($100{\mu}M$)도 CCh 자극으로 인한 타액분비를 억제하였다. 이상의 결과로 미루어

• Maxillofacial Plastic and Reconstructive Surgery
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• 제38권
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• pp.38.1-38.10
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• 2016

Background: The aims of this study are to evaluate the lip morphology and change of lip commissure after mandibular setback surgery (MSS) for class III patients and analyze association between the amount of mandibular setback and change of lip morphology. Methods: The samples consisted of 14 class III patients treated with MSS using bilateral sagittal split ramus osteotomy. Lateral cephalogram and cone-beam CT were taken before and about 6 months after MSS. Changes in landmarks and variables were measured with 3D software program $Ondemand^{TM}$. Paired and independent t tests were performed for statistical analysis. Results: Landmarks in the mouth corner (cheilion, Ch) moved backward and downward (p < .005, p < .01). However, cheilion width was not statistically significantly changed. Landmark in labrale superius (Ls) was not altered significantly. Upper lip prominence angle (ChRt-Ls-$ChLt^{\circ}$) became acute. Landmarks in stomion (Stm), labrale inferius (Li) moved backward (p < .005, p < .001). Lower lip prominence angle (ChRt-Li-$ChLt^{\circ}$) became obtuse (p < .001). Height of the upper and lower lips was not altered significantly. Length of the upper lip vermilion was increased (p =< 0.01), and length of the lower lip vermilion was decreased (p < .05). Lip area on frontal view was not statistically significantly changed, but the upper lip area on lateral view was increased and change of the lower lip area decreased (p > .05, p < .005). On lateral view, upper lip prominent point (UP) moved downward and stomion moved backward and upward and the angle of Ls-UP-Stm ($^{\circ}$) was decreased. Lower lip prominent point (LP) moved backward and downward, and the angle of Stm-LP-Li ($^{\circ}$) was increased. Li moved backward. Finally, landmarks in the lower incisor tip (L1) moved backward and upward, but stomion moved downward. After surgery, lower incisor tip (L1) was positioned more superiorly than stomion (p < .05). There were significant associations between horizontal soft tissue and corresponding hard tissue. The posterior movement of L1 was related to statistically significantly about backward and downward movement of cheilion. Conclusions: The lip morphology of patients with dento-skeletal class III malocclusion shows a significant improvement after orthognathic surgery. Three-dimensional lip morphology changes in class III patients after MSS exhibited that cheilion moved backward and downward, upper lip projection angle became acute, lower lip projection angle became obtuse, change of upper lip area on lateral view was increased, change of lower lip area decreased, and morphology of lower lip was protruding. L1 was concerned with the lip tissue change in statistically significant way.