• Journal of Chest Surgery
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• 제6권2호
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• pp.225-230
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• 1973

Five cases of esophageal cancer developed at the site of esophageal lye stricture were reported. Duration of lye stricture was between 13 and 40years, and all 5 cases had taken normal diet without appreciable troubles after recovery from the acute stage of burn till the suspected onset of esophageal malignaney. Outstanding symptoms of this grave condition were rather acute progressive dysphagia and frequent episodes of esophageal foreign bodies, Diagnosis could be confirmed easily by endoscopic biopsy in suspected eases, and all were epidermoid carcinoma histopathologically. Curative resection of this condition was made in neither of the cases, and their prognoses were more grave than other esophageal malignancies in our experience. The development of esophageal carcinoma at the site of corrosive esophagitis with resulting benign stricture has now been suspected as a cause and effect relationship between these two conditions, and Kiviranta: stated that the incidence of esophageal cancer in patients with lye stricture of longer duration is a thousand times higher than normal population. During last one decade the authors experienced 5 cases of esophageal carcinoma developed at the site of lye stricture of the esophagus among about 350 cases of lye burned esophagus at the Department of Thoracic & Cardiovascular Surgery, the National Medical Center in Seoul, Korea. In Korea they still use lye as a detergent in rural area, and there are still many persons ingesting lye for suicidal attempt or on accident. Lye stricture of the esophagus is, therefore, the most common esophageal disease needing surgical procedures, and the authors believe that there will be much more eases of lye stricture complicated by esophageal eareinoma repoted in near future in this Country.

• Journal of Yeungnam Medical Science
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• 제5권1호
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• pp.181-189
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• 1988

저자들은 경련성 발작후 의식소실이 자주 발생하였으며 그로 인해 항경련제를 장기간 투여하였고 저혈당으로 인한 의시소실의 상태로 내원한 비만한 여자 성인 환자에서 Insulinoma를 경험하였기에 문헌 고찰과 함께 보고하고자 한다.

• Asian Journal of Atmospheric Environment
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• 제6권1호
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• pp.41-52
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• 2012

Particulate sulfate in $PM_{2.5}$, sulfur dioxide ($SO_2$) and size-segregated aerosol particle number concentrations were measured at a site ($32^{\circ}19'N$, $129^{\circ}59'E$) on the southwestern Japan coast from 5 March to 10 April, 2010. Results show frequent episodic increases of sulfate and $SO_2$. Compared to the average concentration of sulfate $4.4{\pm}2.7\;{\mu}g\;m^{-3}$ in the whole observation period, episodic sulfate reached $10.5-20.1\;{\mu}g\;m^{-3}$. The variation of sulfate always synchronized with aerosol particles in the size range of $0.1-0.5 {\mu}m$, indicating the episodic sulfate was a consequence of the increase of the sub-micron particles. $SO_2$ did not have remarkable increase in any episodes of sulfate increase. During the passage of low pressure systems which loaded Asian dust in postfrontal air, concentrated sulfate appeared right behind the front but before dust arrival, suggesting the dominance of dust-free particulate sulfate. Weather and backward trajectory analyses revealed that air parcels with high sulfate passed eastern and northeastern China or Korean peninsula before arriving at the site. In contrast, those with high $SO_2$ passed an active volcano, Mt. Sakurajima, about 100 km in the south, suggesting the $SO_2$ was more likely from the volcanic emission. The ratio of sulfate to total sulfur compounds $({SO_4}^{2-})/({SO_4}^{2-}+SO_2)$ was 0.31-0.89 in continentally originated air while was 0.25-0.43 in the air having passed the volcano, showing more efficient conversions of $SO_2$ to sulfate in the air from the continent. The close dependence of the conversion on humidity in the continentally originated air was confirmed.

• 한국산학기술학회논문지
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• 제12권1호
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• pp.459-466
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• 2011

이 논문에서는 침입 탐지시스템의 체계적인 경보데이터관리 및 경보데이터 상관관계 분석을 위하여 데이터 마이닝 기법을 적용한 경보 데이터 마이닝 프레임워크를 제안한다. 적용된 마이닝 기법은 속성기반 연관규칙, 속성기반 빈발에피소드, 오경보 분류, 그리고 순서기반 클러스터링이다. 이들 구성요소들은 각각 대량의 경보 데이터들로부터 알려지지 않은 패턴을 탐사하여 공격시나리오를 유추하거나, 공격 순서를 예측하는 것이 가능하며, 데이터의 그룹화를 통해 고수준의 의미를 추출할 수 있게 해준다. 실험 및 평가를 위하여 제안된 경보데이터 마이닝 프레임워크의 프로토타입을 구축하였으며 프레임워크의 기능을 검증하였다. 이 논문에서 제안한 경보 데이터 마이닝 프레임워크는 기존의 경보데이터 상관관계분석에서는 해결하지 못했던 통합적인 경보 상관관계 분석 기능을 수행할 뿐만 아니라 대량의 경보데이터에 대한 필터링을 수행하는 장점을 가진다. 또한 추출된 규칙 및 공격시나리오는 침입탐지시스템의 실시간 대응에 활용될 수 있다.

• 한국정보과학회논문지:데이타베이스
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• 제31권1호
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• pp.1-12
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• 2004

최근 네트워크 구성이 복잡해짐에 따라 정책기반의 네트워크 관리기술에 대한 필요성이 증가하고 있으며, 특히 네트워크 보안관리를 위한 새로운 패러다임으로 정책기반의 네트워크 관리 기술이 도입되고 있다. 보안정책 서버는 새로운 정책을 입력하거나 기존의 정책을 수정, 삭제하는 기능과 보안정책 결정 요구 발생시 정책결정을 수행하여야 하는데 이를 위해서는 보안정책 실행시스템에서 보내온 경보 메시지에 대한 분석 및 관리가 필요하다. 따라서 이 논문에서는 정책기반 네트워크 보안관리 프레임워크의 구조 중에서 보안정책 서버의 효율적인 보안정책 수립 및 수행을 지원하기 위한 경보데이타 분석기를 설계하고 구현한다. 경보 데이타 저장과 분석을 위해서 데이타베이스 스키마를 설계하고 저장된 경보데이타를 분석하는 모듈을 구현하며 경보데이타 마이닝 엔진을 구현하여 경보데이타를 효율적으로 분석하고 이를 통해 경보들의 새로운 유사패턴그룹이나 공격시퀀스를 유추하여 능동적인 보안정책관리를 지원할 수 있도록 한다.

• Clinical and Experimental Pediatrics
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• 제59권2호
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• pp.74-79
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• 2016

Purpose: Febrile seizure, the most common type of pediatric convulsive disorder, is a benign seizure syndrome distinct from epilepsy. However, as epilepsy is also common during childhood, we aimed to identify the prognostic factors that can predict epilepsy in children with febrile seizures. Methods: The study comprised 249 children at the Korea University Ansan Hospital who presented with febrile seizures. The relationship between the subsequent occurrence of epilepsy and clinical factors including seizure and fever-related variables were analyzed by multivariate analysis. Results: Twenty-five patients (10.0%) had additional afebrile seizures later and were diagnosed with epilepsy. The subsequent occurrence of epilepsy in patients with a history of febrile seizures was associated with a seizure frequency of more than 10 times during the first 2 years after seizure onset (P<0.001). Factors that were associated with subsequent occurrence of epilepsy were developmental delay (P<0.001), preterm birth (P =0.001), multiple seizures during a febrile seizure attack (P =0.005), and epileptiform discharges on electroencephalography (EEG) (P =0.008). Other factors such as the age at onset of first seizure, seizure duration, and family history of epilepsy were not associated with subsequent occurrence of epilepsy in this study. Conclusion: Febrile seizures are common and mostly benign. However, careful observation is needed, particularly for prediction of subsequent epileptic episodes in patients with frequent febrile seizures with known risk factors, such as developmental delay, history of preterm birth, several attacks during a febrile episode, and epileptiform discharges on EEG.

• Pediatric Infection and Vaccine
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• 제5권2호
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• pp.289-295
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• 1998

Group B Streptococcal sepsis and/or meningitis is one of the most serious and common diseases in the neonatal period with high mortality and frequent complications. We have experienced a case of late onset type group B streptococcal sepsis and meningitis with a complication of subclavian vein catheterization catheterization. This 29-day-old male neonate was admitted to intensive care unit with the presentation of fever and septic shock. He was born with Cesarean delivery at 36 weeks and 3 days of gestational age. He showed multiple episodes of seizure after admission and group B streptococcus was isolated from blood. CSF profiles 10 days after admission showed the features of bacterial meningitis without organism isolated. Diffuse cerebral infarction was detected on brain CT 24 days after admission. In the 13th hospital day, the complication of subclavian vein catheterization occurred; Guide wire was cut during insertion and the distal portion of it(2.5cm) was retained in the left subclavian vein. We removed the retained guide wire with goose-neck snare catheter via right femoral vein. This case was presented with a brief review of the literatures.

• 한국환경과학회지
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• 제26권12호
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• pp.1375-1387
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• 2017

In order to investigate the $PM_{10}$ concentration trend and its characteristics over five different sub area in Busan from 2013 to 2015, data analysis with considering air flow distribution according to its topography was carried out using statistical methodology. The annual mean concentrations of $PM_{10}$ in Busan tend to decrease from $49.6{\mu}g/m^3$ in 2013 to $46.9{\mu}g/m^3$ in 2015. The monthly mean concentrations value of $PM_{10}$ were high during spring season, from March to May, and low during summer and fall due to frequent rain events. The concentration of $PM_{10}$ was the highest in five different sub-area in Busan. High concentration episodes over 90 percentile of daily $PM_{10}$ concentration were strongly associated with mean daily wind speed, and often occurred when the westerly wind or southwesterly wind were dominant. Regardless of wind direction, the highest correlation of $PM_{10}$ concentrations was observed between eastern and southern regions, which were geographically close to each other, and the lowest in the western and eastern regions blocked by mountains. Wind flow along the complex terrain in Busan is also one of the predominant factors to understand the temporal variation of $PM_{10}$ concentrations.

• Journal of Microbiology
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• 제43권2호
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• pp.133-143
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• 2005

Shigellosis is a global human health problem. Four species of Shigella i.e. S. dysenteriae, S. flexneri, S. boydii and S. sonnei are able to cause the disease. These species are subdivided into serotypes on the basis of O-specific polysaccharide of the LPS. Shigella dysenteriae type 1 produces severe disease and may be associated with life-threatening complications. The symptoms of shigellosis include diarrhoea and/or dysentery with frequent mucoid bloody stools, abdominal cramps and tenesmus. Shigella spp. cause dysentery by invading the colonic mucosa. Shigella bacteria multiply within colonic epithelial cells, cause cell death and spread laterally to infect and kill adjacent epithelial cells, causing mucosal ulceration, inflammation and bleeding. Transmission usually occurs via contaminated food and water or through person-to-person contact. Laboratory diagnosis is made by culturing the stool samples using selective/differential agar media. Shigella spp. are highly fragile organism and considerable care must be exercised in collecting faecal specimens, transporting them to the laboratories and in using appropriate media for isolation. Antimicrobial agents are the mainstay of therapy of all cases of shigellosis. Due to the global emergence of drug resistance, the choice of antimicrobial agents for treating shigellosis is limited. Although single dose of norfloxacin and ciprofloxacin has been shown to be effective, they are currently less effective against S. dysenteriae type 1 infection. Newer quinolones, cephalosporin derivatives, and azithromycin are the drug of choice. However, fluoroquinolone-resistant S. dysenteriae type 1 infection have been reported. Currently, no vaccines against Shigella infection exist. Both live and subunit parenteral vaccine candidates are under development. Because immunity to Shigella is serotype-specific, the priority is to develop vaccine against S. dysenteriae type 1 and S. flexneri type 2a. Shigella species are important pathogens responsible for diarrhoeal diseases and dysentery occurring all over the world. The morbidity and mortality due to shigellosis are especially high among children in developing countries. A recent review of literature (KotIoff et al.,1999) concluded that, of the estimated 165 million cases of Shigella diarrhoea that occur annually, $99\%$ occur in developing countries, and in developing countries $69\%$ of episodes occur in children under five years of age. Moreover, of the ca.1.1 million deaths attributed to Shigella infections in developing countries, $60\%$ of deaths occur in the under-five age group. Travellers from developed to developing regions and soldiers serving under field conditions are also at an increased risk to develop shigellosis.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권2호
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• pp.142-151
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• 2019

Purpose: The aim of the study was to identify factors related to the recurrence of intussusception in pediatric patients. Methods: The medical charts of patients diagnosed with intussusception and treated at Dongsan Medical Center, between March 2015 to June 2017, were retrospectively reviewed. Univariate and multivariate analyses were performed. Results: Among 137 patients, 23 patients (16.8%) had a recurrent intussusception and 8 of these patients (6%) had more than 2 episodes of recurrence. The age at diagnosis was significantly different between the non-recurrence and recurrence group (p=0.026), with age >1 year at the time of diagnosis associated with a greater rate of recurrence (p=0.002). The time interval from symptom onset to the initial reduction (<48 vs. ${\geq}48$ hours) was significantly longer in the recurrence group (p=0.034) and patients in the recurrence group had higher levels of C-reactive protein (CRP) (p=0.024). Bloody stools and a history of infection were significantly more frequent in the non-recurrence group (p=0.001 and p<0.001, respectively). On stepwise regression analysis, age >1 year at the time of presentation (odds ratio [OR], 4.79; 95% confidence interval [CI], 1.56-14.06; p=0.016) and no history of infection (OR, 0.18; 95% CI, 0.06-0.58; p=0.004) were retained as predictors of recurrence. Conclusion: Patients with intussusception who are older than 1 year at diagnosis, have an elevated CRP level, a delay of ${\geq}48$ hours between symptom onset and the initial reduction, an absence of bloody stools, and no history of infection should be closely monitoring for symptoms and signs of a possible recurrence.