• 제목/요약/키워드: Freezing Method

검색결과 692건 처리시간 0.024초

점안용 소염약침액의 안점막자극실험 (Eye Irritation Test of Soyeom Pharmacopuncture Solution for Eye Drop)

  • 서형식
    • 대한약침학회지
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    • 제11권2호
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    • pp.75-79
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    • 2008
  • Objectives This study was done to investigate the safety of Soyeom pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration(2005. 10. 21, KFDA 2005-60). After Soyeom pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Soyeom pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn't physical problem at 9 rabbits. 2. After Soyeom pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn't eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions I suggested that Soyeom pharmacopuncture solution didn't induced eye irritation in rabbits.

점안용 우황약침액의 안점막자극실험 (Eye Irritation Test of Bovis Calculus Pharmacopuncture Solutions for Eye Drop)

  • 서형식
    • 대한약침학회지
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    • 제11권2호
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    • pp.81-85
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    • 2008
  • Objective This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration (2005. 10. 21, KFDA 2005-60). After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results 1. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn't physical problem at 9 rabbits. 2. After Bovis Calculus pharmacopuncture solutionwas medicated in the left eye of the rabbits, there wasn't eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions I suggested that Bovis Calculus pharmacopuncture solution didn't induced eye irritation in rabbits.

Encapsulation of Plasmid DNA in Pegylated Liposome

  • Jang, Jung-Ok;Gwak, Hye-Sun;Lee, Hwa-Jeong
    • Journal of Pharmaceutical Investigation
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    • 제35권5호
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    • pp.337-341
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    • 2005
  • The purpose of the study was to prepare the pegylated liposome carrying plasmid DNA with optimal encapsulation efficiency. Plasmid DNA (pCEP4 clone 790, 10.6 kb) was entrapped in the pegylated liposome composed of neutral lipid, POPC (l-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine), cationic lipid, DDAB (dimethyl dioctadecyl ammonium bromide) and anionic lipids, DSPE-PEG 2000 (distearoyl phosphatidyl ethanolamine polyethylene glycol 2000) and DSPE-PEG 2000-maleimide by freezing/thawing method. Free plasmid DNA was separated from the encapsulated one by Sepharose CL-4B column chromatography. The DNA amount encapsulated into the pegylated liposome was increased as cationic lipid concentration, initial amount of plasmid DNA and total lipid amount were increased.

CKD 혼합에 따른 Recycled Material의 회복탄성계수와 일축압축강도 특성 (Characteristic of Resilient Modulus and Unconfined Compressive Strength for Recycled Materials blend with Cement Kiln Dust)

  • 손영환
    • 한국농공학회논문집
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    • 제52권2호
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    • pp.19-25
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    • 2010
  • This study was conducted to determine the resilient modulus (Mr) and the unconfined compressive strength (UCS) of two recycled roadway materials such as recycled pavement material (RPM) and road surface gravel (RSG) with or without cement kiln dust (CKD). The recycled materials were blended with two CKD contents (5, 10 %) and 28 day curing time. Mr and UCS tests were also conducted after 10cycles of freezing and thawing to asses the impact of freeze-thaw cycling. Mr was determined conducting by the laboratory test method described by NCHRP 1-28A. Stabilized RPM and RSG had a modulus and a strength higher than unstabilized RPM and RSG. Mr and UCS of RPM and RSG mixed with CKD increased with increasing CKD content. The results indicated that the addition of CKD could be improved the strength and the stiffness of RPM and RSG. Therefore, RPM, RSG and CKD could be used as an effective materials in the reconstruction of roads.

배수갑문 교량의 노후도 감시시스템 (Management System for Saemangeum Gate Bridge)

  • 이준구;조영권;김한중;김관호;김명원
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2006년도 춘계 학술발표회 논문집(II)
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    • pp.241-244
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    • 2006
  • The basic prediction model was constructed to obtain optimal maintenance method for concrete structure under marine environment by exploring the mechanism of mono and combined deterioration in lab. This model was planned to be upgraded with data acquired from several exposure specimens under same environment as structures. The computer program developed to give useful guidance observer would be improved. Several repair materials and repair construction methods applied to exposure specimens will be tested for its performance of prohibit salt attack and freezing & thawing action during experimental period about ten years. All of these data could be available to complete the prediction system. The manager will be able to use the system for optimal maintenance of marine concrete structures.

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고로슬래그 미분말이 혼입된 ECC(Engineered Cementitious Composite)의 내구성 평가 (Evaluation of durability of an ECC(Engineered Cementitious Composite) designed with ground granulated blast furnace slag)

  • 김정수;김윤용;김진근;하기주
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2006년도 춘계 학술발표회 논문집(II)
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    • pp.329-332
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    • 2006
  • This paper presents the experimental results for durability of an ECC designed with ground granulated blast furnace slag (BFS) through the test method of chloride ion resistance and freezing-thawing resistance. In order to compare with ECC, normal mortar was also tested. Test results showed that BFS ECC exhibited higher durability performance than ordinary mortar. These results suggest that by adding BFS in ECC, its matrix density is increased which results in decreased of deterioration and it also adds to the fiber bridging that contributes in control of cracking.

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콘크리트 내부 온습도 변화 예측에 관한 수치모델 구축 및 실측 (The Analytic and Experimental Study on the Expectation of the Thermal-Moisture Transfer in the Concrete)

  • 박동천;오상균;김정진
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2009년도 춘계 학술대회 제21권1호
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    • pp.265-266
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    • 2009
  • 콘크리트의 내구성, 즉 염해, 증성화, 동해, 화학적 침식 등의 열화현상을 예측하기 위해서는 우선 콘크리트 내부의 온습도를 파악하는 것이 무엇보다도 중요하다. 본 연구에서는 열-수분 이동을 고려 한 복합 물리적 모델 구축 및 실측을 통하여 시간경과에 따른 콘크리트 내부의 온습도 변화를 추정하고자 하였다.

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해양콘크리트 구조물의 노후도 예측시스템 개발 연구 (Prediction System of Deterioration Ratio for Marine Concrete Structures)

  • 이준구;박광수;조영권;이창수;김한중
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2005년도 추계 학술발표회 제17권2호
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    • pp.531-534
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    • 2005
  • The basic prediction model was constructed to obtain optimal maintenance method for concrete structure under marine environment by exploring the mechanism of mono and combined deterioration in lab. This model was planned to be upgraded with data acquired from several exposure specimens under same environment as structures. The computer program developed to give useful guidance observer would be improved. Several repair materials and repair construction methods applied to exposure specimens will be tested for its performance of prohibit salt attack and freezing & thawing action during experimental period about ten years. All of these data could be available to complete the prediction system. The manager will be able to use the system for optimal maintenance of marine concrete structures.

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고정화된 백색부후균을 이용한 염료의 탈색에 관한 연구 (A Study on Decolorization of Dyes with an Immobilized White Rot Fungus Irpex lacteus)

  • 원찬희;김종신;박상숙
    • 한국환경과학회지
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    • 제7권3호
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    • pp.263-268
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    • 1998
  • Decolorization of congo red, rhodamlne B was investigated by the white rot fungus Irpex lacteus welch has biodegrading capability of various recalcitrants. White rot fungus Irpex lacteus is Immobilized by PVA-freezing method. An Immobilized Irpex lacteus decolorizes 91% of congo red In 8 days under culture with glucose 2%(Initial cone.). It also showed 70% of decolorization at 3 days In the state of putting MnSO4 1mM. But, rhodauune B has no significant differences about decolorization among different mixture ratio of Irprx lacteus with PVA, concentration of carbon, nitrogen and manganese sulfate.

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다공성 매질 내에서 메탄 하이드레이트의 분해에 의한 2 상 유동 해석 (Simulation of Two Phase Flow in Porous Media After Disso of Methane Hydrates)

  • 장동근;김남진;이재용;김종보
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2000년도 추계학술대회논문집B
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    • pp.241-246
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    • 2000
  • Gas hydrates are solid solutions when water molecules are linked through hydrogen bondin create host lattice cavities that can enclose a large variety of guest gas molecules. The natural hydrate crystal may exist at low temperature above the normal freezing point of water and pressure greater than about 30 bars. A lot of quantities of natural gas hydrates exists in the ear many production schemes are being studied. In the present investigation, depressurization method considered to predict the production of gas and the simulation of the two phase flow - gas and - in porous media is being carried out. The simulation show about the fluid flow in porous have a variety of applications in industry. Results provide the appearance of gas and water prod the pressure profile, the saturation of gas/ water/ hydrates profiles and the location of the pl front.

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