• Title/Summary/Keyword: Free-Formed Structure

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APPLICATION OF THREE DIMENSIONAL CULTURE OF ADULT RAT HAPATOCYTES IN POLYURETHANE FOAM PORES FOR AN ARTIFICIAL LIVER SUPPORT SYSTEM

  • Funatsu, K.;Matsushita, T.;Ijima, H.;Iwahashi, T.
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.137-144
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    • 1994
  • Spherical multicellular aggregates of adult rat hepatocytes (spheroid) which have tissue like structure, were formed and immobilized in the pores of polyurethane foam (PUF) which was used as a culture substratum. These hepatocyte/spheroids, about 100 $\mu\textrm{m}$ in diameter, have maintained higher differentiated functions than those of hepatocyte/monolayer for about 3 weeks in serum-free medium. Then, we designed a prototype module of an artificial liver support system using a PUF/spheroid packed-bed, in which hepatocyte/spheroids were immobilized at high density. The urea synthesis activity of the artificial liver was maintained at least 10 days in 100% rat blood plasma. We start examining the performance of hybrid artificial liver in an ex vivo extracorporeal experiment with an acute hepatic failure rat.

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Synthesis of $CA_2$-based Clinker by Hydration-Burning Method (I) : Effects of Temperature on Synthesis (수화-소성법에 의한 $CA_2$클린커의 합성(I) : 합성에 미치는 온도의 영향)

  • 송태웅;한기성
    • Journal of the Korean Ceramic Society
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    • v.27 no.2
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    • pp.211-218
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    • 1990
  • CA2-based clinker with highly activated surface and hydraulic properties was synthesized at a comparatively lowr temperature than that of conventional synthesis by "hydration-burning method". This consists of calcining the mixture of CaCO3 and Al2O3 to obtain a primary clinker, hydrating the primary clinker and reburning the hydrates to obtain final clinker. Burning of primary clinker above 1200℃ was necessary to eliminate free CaO in it and to obtain it's solid hydrate. However, rising the burning temperature above 1300℃ is ineffective due to the decrease in hydraulic properties of the primary clinker with the temperature. Hydration of primary clinker at the elevated temperature(>35℃) was required to obtain the hydrate with more porous structure and final clinker with more active surface. CA2 was formed and increased with temperature at above 1150℃, finally became a primary phase of the final clinker. However, burning at the temperature above 1300℃ resulted in reverse effect on the hydraulic properties of the final clinker due to rapid decrease in it's surface area with the temperature.

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Dehydropolycondensation of Aminophenols under the Catalytic Acition of Metallic Chelate Compounds (Ⅲ) Reactions of the Isomers, Reaction Mechanisms, and the Structures of the Oligomers (金屬킬레이트 化合物의 觸媒作用에 依한 Aminophenol 類의 酸化的 重縮合反應 (Ⅲ) 異性體의 反應, 反應機構 및 生成物의 構造)

  • Choi, Kyu-Suck
    • Journal of the Korean Chemical Society
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    • v.12 no.3
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    • pp.128-137
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    • 1968
  • In the oligomerization of p-aminophenol by the catalytic action of Fe-EDTA complex in the aqueous medium, the mixed complex intermediate, Fe-EDTA-M type, is considered to be formed, from which active radicals of the monomer are produced. In this system, polymerization is presumed to proceed as follows: Free radical formation ${\to}$ Coupling ${\to}$ Activation ${\to}$ Coupling, and so on. In this study, the form of the monomer and coordination state in the mixed complex, the catalytic action of Fe-EDTA the complex, the reaction mechanism, and the structure of the oligomers are discussed.

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The Effect of Arsenic on Copper Electrodeposition in Copper-Sulfate Solutions in Copper-Electrorefining (동 전해정련시 황산구리 수용액 중의 Arsenic이 구리의 전해전착에 미치는 영향)

  • Kim, Do-Hyung;Kim, Yong-Hwan;Chung, Won-Sub
    • Journal of the Korean institute of surface engineering
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    • v.42 no.3
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    • pp.103-108
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    • 2009
  • The effect of Arsenic in copper-sulfate solutions during electrorefining of copper was investigated using scanning electron microscopy, X-ray diffraction and cyclic voltammetry analysis. Electrodeposition was carried out using Arsenic, Antimony and bismuth addition to sulfate electrolytes: 45 g/l $Cu^{2+}$ and 170 g/l $H_2SO_4$. Arsenic in sulfate electrolytes changed the morphology and structure of the copper deposits as compared with those obtained from impurity free solutions. When arsenic was present in the sulfate electrolytes, $Cu-3$As intermetallic phase was formed locally on the deposits.

Facile Hydrothermal Synthesis and Characterization of the $CeO_2$ Nanorings

  • Arul, N. Sabari;Kim, Tae Whan;Mangalaraj, Devanesan
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.455-455
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    • 2013
  • $CeO_2$ nanorings were synthesized by using a surfactant free hydrothermal method. The surface morphology, structural and optical properties of the synthesized $CeO_2$ was investigated by using scanning electron microscopy (SEM), X-ray diffraction (XRD), and ultraviolet-visible (UV) spectroscopy measurements. SEM images showed that the surface morphology of the formed $CeO_2$ appeared as nanorings. The XRD pattern of $CeO_2$ nanorings showed the presence of the polycrystalline $CeO_2$ phase readily indexed to the cubic fluorite structure of the $CeO_2$. The mean crystallite size of the $CeO_2$ was calculated using the Scherrer equation from the XRD line broadening of the (111) planes of the cubic $CeO_2$. The UV-Visible spectroscopy spectrum of the $CeO_2$ nanorings exhibited a strong UV absorption band around 350 nm.

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Magnetic field detwinning in FeTe

  • Kim, Younsik;Huh, Soonsang;Kim, Jonghyuk;Choi, Youngjae;Kim, Changyoung
    • Progress in Superconductivity and Cryogenics
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    • v.21 no.4
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    • pp.6-8
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    • 2019
  • Iron-based superconductors (IBSs) possess nematic phases in which rotational symmetry of the electronic structure is spontaneously broken. This novel phase has attracted much attention as it is believed to be closely linked to the superconductivity. However, observation of the symmetry broken phase by using a macroscopic experimental tool is a hard task because of naturally formed twin domains. Here, we report on a novel detwinning method by using a magnetic field on FeTe single crystal. Detwinning effect was measured by resistivity anisotropy using the Montgomery method. Our results show that FeTe was detwinned at 2T, which is a relatively weak field compared to the previously reported result. Furthermore, detwinning effect is retained even when the field is turned off after field cooling, making it an external stimulation-free detwinning method.

On the structural behavior of ship's shell structures due to impact loading

  • Lim, Hyung Kyun;Lee, Joo-Sung
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.10 no.1
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    • pp.103-118
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    • 2018
  • When collision accident between ships or between ship and offshore platform occurs, a common phenomenon that occurs in structures is the plastic deformation accompanied by a large strain such as fracture. In this study, for the rational design against accidental limit state, the plastic material constants of steel plate which is heated by line heating and steel plate formed by cold bending procedure have been defined through the numerical simulation for the high speed tension test. The usefulness of the material constants included in Cowper-Symonds model and Johnson-Cook model and the assumption that strain rate can be neglected when strain rate is less than the intermediate speed are verified through free drop test as well as comparing with numerical results in several references. This paper ends with describing the future study.

Somatic Embryogenesis and Adventitious Bud Formation from Zygotic Embryo of Boxthone (Lycium chinense Mill.) (구기자나무(Lycium chinense Mill.) 접합자 배로부터 체세포배 및 부정아 발생)

  • Lee, Jae-Dong;Cho, Duck-Yee;Soh, Woong-Young
    • Journal of Plant Biotechnology
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    • v.29 no.4
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    • pp.241-246
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    • 2002
  • Somatic embryos or adventitious buds were formed from the segments of zygotic embryo of Lycium chinense Mill. on Murashige and Skoog (MS) medium supplemented with auxins (2,4-D, NAA, IAA) and / or cytokinins (zeatin, kinetin, BAP). Embryogenic callus formed on MS medium containing 0.5 mg/L 2,4-D and then differentiated into somatic embryos without transfer to hormone free medium. On the other hand, adventitious buds were formed on medium with 0.01 mg/L 2,4-D and 0.5 mg/L zeatin. Among various parts of zygotic embryos, the morphogenic potential was higher in the cotyledonary region, and the most organogenic potential was found in cotyledon followed by radicle, hypocotyl, and whole embryo. Histologically, bipolar structure of the heart-shaped embryos were confirmed and in adventitious buds only shoot apical meristems were found to exist.

A Study on the Influence of IIT's Educational System on the Jong Soung Kimm's Architecture (김종성 건축과 IIT의 교육시스템과의 관계에 관한 연구)

  • Jung, In-Ha
    • Journal of architectural history
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    • v.10 no.1 s.25
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    • pp.41-59
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    • 2001
  • This study tries to analyze the influence of IIT's educational system on the Jong Soung Kimm's Architecture. Architect Kimm was the first student in Korea who gained admission to the IIT and was directly learned from Mies van der Rohe. At IIT, he completed a university course from 1956 to 1961, and finished a degree of master under the direction of Professor Myron Goldsmith in 1964. After the graduation, he entered Mies's office and became the professeur of IIT from 1966 to 1978. In consideration with these facts, it is no exaggeration to say that Kimm's architecture was formed by the IIT's educational system and Mies's architectural principles. According to the synopsis of the 5-year curriculum 1944-45, the object of architectural work in IIT is the clarification of : 1)the structure as an architectural factor, its possibilities and limitations 2) space as an architectural problem 3) proportion as a means of architectural expression 4) the expression value of materials 5) the application of these principles by means of free creative work. Architect Kimm's works designed in Korea reflect well these objectives. But Kimm also knew well the problems of IIT's educational system. After the retirement of Mies, IIT's educational system had the tendency to overstress the technology of structure and simplify the complexity of Miesian architectural principles. In opposition to this tendency, architect Kimm continued to keep the spacial and formal subtlety which possess the Mies' original architecture. This shows very well the future direction of Kimm's architectural activities.

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Synthesis, spectral, thermal, structural study and theoretical treatment of new complexes of mannich base with Ni(II) and study of cytotoxicity effect on (Hepa-2) cell line and antimicrobial activity

  • Omar H. Al-Obaidi
    • Analytical Science and Technology
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    • v.36 no.2
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    • pp.70-79
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    • 2023
  • The synthesis of the Mannich base as a ligand (L) N-(morpholino (phenyl) methyl) acetamide is the subject of this study. Elemental analyses, FT-IR spectra, UV-vis, 1H-NMR, and magnetic measurements were used to confirm the synthesis of the [Ni(L)2]Cl2 complex, thermal analysis (TG/DTG), atomic absorption, and scanning, and structurally explained as electron microscopy (SEM), and X-ray powder diffraction (XRD) methods. The melting point of the complex and its molar conductivity were also measured. The suggested geometries of the complexes formed have a tetrahedral structure, according to the data acquired using various techniques. Theoretical approaches to the complex formation have been investigated. For molecular mechanics and semi-empirical calculations, the HYPERCHEM6 program had been used. The effect of the novel Ni(II) complex on the cancer cell Hepa-2 (human hepatocellular ademocarcinoma), that is the human laryngeal cancer, was studied. It has been found that these ligand and complex have potent effects on the cancer cell. The antibacterial activity of the free ligand and its complex was evaluated against two kinds of human pathogenic bacteria. The first category is Gram-positive (Staphylococcus aureas, epiderimids), whereas the second group is Gram-negative (Psedamonas aeruginosa, Escherichia coli) (from the diffusion method). Finally, it was discovered that various chemicals had varied growth-inhibiting effects on bacteria.