• Title/Summary/Keyword: Free will

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Identification of Antioxidant Activities and Stimulation of Human Keratinocytes Differentiation Effects of Syzygium claviflorum Extract (Syzygium claviflorum 추출물의 항산화 활성 및 각질형성세포 분화유도 효과)

  • Gayeon Seo;Jiyeon Moon;Yukyung Park;Juyeong Kim;Hoyong Hyun;Beomsu Jeong;Thet Thet Mar Win;Thant Zaw Win;Sangho Choi;Sangmi Eum;Dongwon Kim
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.59-65
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    • 2023
  • We validated the physiological activity of Syzygium claviflorum (Roxb.) Wall. ex A.M. Cowan & Cowan (S. claviflorum) extracts (leaves, stems, fruits, and flowers) as a cosmetic ingredient. Firstly, S. claviflorum extracts removed over 80% of free radicals at various concentrations in antioxidant experiments using the DPPH and ABTS assay. In cytotoxicity experiments using human epidermal keratinocytes, S. claviflorum extracts showed low cytotoxicity. In addition, S. claviflorum extracts significantly increased the expression of keratin (KRT)1, KRT2, KRT9, KRT10, which are differentiation markers of keratinocytes, as well as genes involved in the maintenance of skin barrier function, including involucrin (IVL), loricrin (LOR), filaggrin (FLG), and claudin1 (CLDN1). In particular, the expression of FLG protein, inhibited by interleukin (IL)-4/IL-13 in atopic dermatitis, was restored by S. claviflorum extracts in in vitro experiments. Therefore, S. claviflorum extracts with excellent antioxidant efficacy and skin barrier improvement function will be useful materials for the development of future atopic dermatitis treatments and cosmetics.

Selecting and evaluating microorganism strains to prepare low-salt doenjang for flavoring via the fermentation of rice and soybeans (쌀 및 콩 발효 균주선발과 이를 적용한 조미용 저염된장의 평가)

  • Jo, Seung Wha;Yim, Eun Jung;Kang, Hyeon Jin;Park, Seul Ki;Jeong, Do Youn
    • Korean Journal of Food Science and Technology
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    • v.54 no.1
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    • pp.103-108
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    • 2022
  • This study investigated the strains and fermentation characteristics of used to ferment a mixture of rice and soybeans to manufacture low-salt doenjang for flavoring. The soybean and rice mixture was fermented using three selected strains of Aapergillus oryzae and Bacillus sp. The changes in quality of the fermented products were found to be dependent on the aging period. Therefore, the strain and a suitable aging period were seleted based on the increases in AN, total sugar, and reducing sugar. The fermented products were prepared and mixed, using the selected or commercially available strains (the sample and control, respectively), to create low-salt doenjang. Following this, their characteristics were compared. The sample had a higher content of taste-related ingredients(free amino acid, nucleic acid-related substances) than the control. Using the selected strain to ferment a rice and soybean mixture will thus be expected to enhance the flavor of industrially produced seasoned doenjang.

A Study on the Current Status and System of the Elderly Medical and Welfare Facilities with the Subjects in Busan (노인 의료복지시설의 실태분석 및 시설체계에 관한 연구 - 부산광역시 노인 의료복지시설을 대상으로 -)

  • Kim, Jong Gu
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.6D
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    • pp.685-695
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    • 2010
  • This is the study on the current status and system of the elderly medical and welfare facilities with the subjects in Busan. I investigated the problems related to those by analysing the current status and implementing a survey and then suggested a new facility system as a salvation. At present, the elderly medical and welfare facilities can not receive variety of inmates and also they are operated separatedly so the elderly is not able to receive special treatment and nursing at the same time in one facility. Some nursing facilities can give special treatment by connecting specific hospital when it is necessary, but the connection is not activated than our expectancy at the present. On the base of these problems, this study suggested 'one-stop service system' that can afford to give nursing and special treatment in a place ranging wider areas as the solution. The five types of facility system by integrating the results of survey are as followings. 1) Free special nursing facility + The geriatric hospital. 2) The profit special nursing facility + The geriatric hospital. 3) The geriatric hospital + The hospital rooms with silver town residence type. 4) The actual expense special nursing facility + The geriatric hospital + The hospital rooms with silver town residence type. 5) The geriatric hospital + The residential welfare service. It seems that the preparation for the elderly is urgent when considering the facilities related to those are not special any more because every one is supposed to use them some day. The kinds and the degree of elderly's diseases will be more duplicated and significant afterwards. Therefore it is expected that more various and specialized facilities are to be required.

Experimental Study on the Analysis and Estimation of Metacentric Height in Response to Roll Period and Moment of Inertia Variations in Ships (선박의 횡요주기와 관성모멘트 변화에 따른 GM 추정 및 분석을 위한 실험 연구)

  • LeeChan Choi;JungHwi Kim;DongHyup Youn
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.29 no.4
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    • pp.380-388
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    • 2023
  • This study estimates the metacentric height (GM) of a model ship by varying the transverse weight distribution, considering the effects of the roll period and moment of inertia, and compares it with the GM values measured by the inclining test. In the process, the relationship between the values is analyzed. Three types of ships-a 7-ton fishing vessel, 20-ton fishing vessel, and KRISO Very Large Crude-oil Carrier (KVLCC)-were used for the experiment and comparison. The roll period and moment of inertia were measured using the free roll decay and swing frame tests, and the GM was measured using inclining test. The estimated GM from the roll period and moment of inertia showed the same trend as the GM measured using the inclining test in the change of the weight distribution. However, the GM values measured using the inclining test were lower. Therefore, additional correction factors or parameters other than the roll period and moment of inertia are necessary for estimating GM. In the future, the relationship between the weight center and the estimated GM will be analyzed to derive the correction factors.

Unsteady Aerodynamic Characteristics of an Non-Synchronous Heaving and Pitching Airfoil Part 1 : Frequency Ratio (비동기 히브 및 피치 운동에 따른 에어포일 비정상 공력 특성 Part 1 : 진동 주파수 비)

  • Seunghwan Ji;Cheoulheui Han
    • Journal of Aerospace System Engineering
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    • v.17 no.6
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    • pp.54-62
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    • 2023
  • Flapping-wing air vehicles, well known for their free vertical take-off and excellent flight capability, are currently under intensive development and research. While most of the studies have explored the effect of various parameters of synchronized motions on the unsteady aerodynamics of flapping wings, limited attention has been given to the effect of nonsynchronous motions on the unsteady aerodynamic characteristics of flapping wings. In the present study, we conducted a numerical analysis to investigate the unsteady aerodynamic characteristics of an airfoil flapping with different frequency ratios between pitch and heave oscillations. We identified the motions and angle of attacks due to nonsynchronous motions. It was found that the synchronous motion produced thrust with zero lift, but the nonsynchronous motion generated a large lift with little drag. The aerodynamic characteristics of the airfoil undergoing the non-synchronous motion were also analyzed using the vorticity distributions and the pressure coefficient around and on the airfoil. When r was equal to 0.5, larger leading and trailing edge vortices were observed compared to the case when r was equal to 1.0, and these vortices significantly affected the aerodynamic characteristics of the airfoil undergoing the nonsynchronous motion. In future, the effect of pitch amplitude on the unsteady aerodynamic characteristics of the airfoil will be studied.

Investigation of USGS Short-Wave Infrared Databases and Comparison with Domestic Cases - Focusing on the Availability for the Mineralogical Analyses and an Application on the Domestic Illite - (USGS 단파장 적외선 데이터베이스 분석 및 국내 사례와 비교: 광물학적 활용도 고찰 및 국내 산출 일라이트로의 적용 사례)

  • Chang Seong Kim;Raeyoon Jeong;Soon-Oh Kim;Ji-man Cha
    • Korean Journal of Mineralogy and Petrology
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    • v.36 no.4
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    • pp.259-271
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    • 2023
  • Since the short-wave infrared spectrum has a significant range of variation depending on the production environment, countries with advanced resource exploration are collecting the spectrum and building a database. Representative organizations include the USGS and CSIRO, and they are currently carrying out a project in China that can synthesize and use a large number of existing data. The USGS library provides a total of 2,457 spectra targeting not only minerals but also various materials that respond to infrared radiation. Among these, there are 1,276 mineral spectra, which are about half of the total. The spectrum title includes information, such as analysis devices (NIC4, BECK, ASDNG, etc.), purity codes (a, b, c, d, u), and measurement methods (AREF, RREF, RTGC, TRAN). Analyzed raw data are provided in ASCII and GIF format. The CSIRO library has a total of 502 spectra, of which the majority, 493, correspond to mineral spectra. The USGS library is a free, publically available resource, while the CSIRO library is bundled with TSG8 or must be purchased separately. Among these, when comparing the eight spectra whose spectral shapes can be analyzed with the spectra of domestic illite, the positions of the absorption peaks are significantly different from those of domestic illite, except for one Japanese illite. Additional research will be needed to determine the causes of such differences, and the domestically relevant databases should be established as well.

College students' implicit theory of Korean creativity and creative environment (한국적 창의성과 창의적 환경에 대한 대학생들의 암묵적 이론)

  • Eun-Hyun Sung ;SoonMi Han ;JooHyun Ha ;JeongKyu Lee;HyungSeon Ryu ;YunYung Han ;Byung-Gee Bak
    • Korean Journal of Culture and Social Issue
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    • v.14 no.1_spc
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    • pp.367-390
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    • 2008
  • The primary purpose of this study is to investigate the college students' implicit theory of Korean creativity. This study deals with the degree to which the students exploit the creativity, and the obstacles for them to exploit the creativity. Another purpose of this study is to explore their implicit knowledge of Korean creative environments. The results are as follows. The implicit knowledge of Korean creativity could be characterized by the following key words: 'flexibility', 'application', 'transformation', 'originality', 'perseverance', 'not being stereotyped', 'esthetic flavor' and 'understanding-new-by-exploring-old'. Students thought themselves to be more or less creative. Students in art and physical education, and male students estimated themselves more creative than other discipline and female. They thought that socio-institutional factors such as educational system focused on the college entrance test are the most serious obstacles against creativity. About half of the students thought the creative persons would have been raised in poor family whereas other students thought differently. The home environment of the creative person was thought to be characterized by the words such as democratic, free and encouraging. Creative persons were thought to be maladaptive school life, but good at peer relations. This study will be used as a pioneer research which suggest a model of Korean creativity.

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Evaluation of Bonding Performance of Hybrid Materials According to Laser and Plasma Surface Treatment (레이저 및 플라즈마 표면처리에 따른 이종소재 접합특성평가)

  • Minha Shin;Eun Sung Kim;Seong-Jong Kim
    • Composites Research
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    • v.36 no.6
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    • pp.441-447
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    • 2023
  • Recently, as demand for high-strength, lightweight materials has increased, there has been great interest in joining with metals. In the case of mechanical bonding, such as bolting and riveting, chemical bonding using adhesives is attracting attention as stress concentration, cracks, and peeling occur. In this paper, surface treatment was performed to improve the adhesive strength, and the change in adhesive strength was analyzed. For the adhesive strength test were conducted with Carbon Fiber Reinforced Plastic(CFRP), CR340(Steel), and Al6061(Aluminum), and laser and plasma surface treatment were used. After plasma surface treatment, the adhesive strength improved by 7.3% and 39.2% in CFRP-CR340 and CFRP-Al6061, respectively. CR340-Al6061 was improved by 56.2% in laser surface treatment. Surface free energy(SFE) was measured by contact angle after plasma treatment, and it is thought that the adhesion strength was improved by minimizing damage through a chemical reaction mechanism. For laser surface treatment, it is thought that creates a rough bonding surface and improves adhesive strength due to the mechanical interlocking effect. Therefore, surface treatment is effect to improve adhesive strength, and based on this paper, the long-term fatigue test will be conducted to prevent fatigue failure, which is a representative cause of actual structural damage.

The Effects of Proportion of Lead Investors and Investors' status on Investment Growth in VC Syndications (신디케이트 내부 VC 리드투자자 비중과 투자자 지위가 투자 성과에 미치는 영향력에 관한 연구)

  • Kim, Jieun;Oh, Jooyeon;Gao, Mengjin;Kim, YoungKyu
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.17 no.1
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    • pp.1-12
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    • 2022
  • This paper examines the influence of the portion of lead investors and investors' status on the investment performance of venture syndication. According to existing literature, multiple investors in VC syndicates can positively impact investment performance by investing both tangible and intangible resources in target companies based on market influence or high visibility. On the other hand, the presence of multiple leaders can cause conflicts in formulating and implementing investment strategy or free-riding problems or increase entry barriers for potential investors, lowering additional investment from existing investors. Therefore, we hypothesize that the relationship between proportion of lead investors and investment performance is inverted-U shape. Moreover, we predict that the status of VCs in the syndication will moderate the relationship between proportion of lead investors and investment performance since high-status actors are less likely to cooperate with or yield power to others. We tested these hypotheses using 24,677 VC syndicated investment data from 1991 to 2005 and found solid supports for the hypotheses. The findings suggest that firms need to consider relationship-based power dynamics among investors within a syndication and design effective role setting and coordination systems.

Improvement Plan for Construction Management and Legislation of Donation Collection Facilities (기부채납 시설의 건설관리 및 법제에 관한 개선방안)

  • Lee, Juyong;Jung, Youngchul
    • Korean Journal of Construction Engineering and Management
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    • v.25 no.1
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    • pp.3-12
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    • 2024
  • The donation collection system to secure infrastructure and land necessary for public development projects has been actively applied as an effective means of realizing public interest and the concept of recovering development profits, and has contributed greatly to society in public difficult financial conditions. However, due to the ambiguous legal standards and lack of legal grounds for the operation of the donation collection system, it has been arbitrarily used for administrative convenience in the form of granting a donation collection assistant to install infrastructure. In addition, infrastructure is a facility that is constructed and donated within development profits to obtain licenses, and is promoted to minimize construction costs to improve profitability, posing a risk of poor infrastructure planning, design, and construction, resulting in increased safety and maintenance costs for citizens. Continuous system and legal improvement are needed to improve the excellence, convenience, and safety of facilities that citizens will use for half a century through the improvement of the donation system.