• Title/Summary/Keyword: Forensic Medicine

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Correlation of ketone bodies in blood and spleen

  • Sookyung Jeon;Sumin Lee;Wooyong Park;Chihyun Park;Minjung Kim
    • Analytical Science and Technology
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    • v.36 no.4
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    • pp.170-179
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    • 2023
  • Starvation, diabetes, alcoholism and hypothermia cause ketoacidosis in the human body; therefore, the cause of death can be determined by analyzing ketone bodies in the blood of the deceased. In the case of decomposition of the cadaver, however, since collecting intact blood is impossible, ketone body analysis is performed using the spleen. However, the index for diagnosing ketoacidosis is based on blood concentration, and its correlation with ketone bodies present in the spleen remains unknown. In particular, since decomposition proceeds rapidly during summer, when temperature and humidity are high, understanding the correlation between ketone bodies in the blood and spleen is important to estimate the state at the time of death from a decaying body. Therefore, in the present study, the correlation between ketone bodies in the blood and spleen of the deceased was explored. Ketone bodies (beta-hydroxybutyric acid [BHB] and acetone) in the blood and spleen were analyzed and compared from autopsies (>100 mg·L-1 BHB, blood basis) conducted at the Daejeon Forensic Research Institute from June to December 2021. Moreover, the concentration of ketone bodies in the spleen juice and tissues was compared assuming the scenario of extreme decomposition. Ketone retention concentration in the blood and spleen was positively correlated, and the ratio of BHB concentration in the spleen to BHB concentration in the blood ranged from 0.52 to 1.08 (mean = 0.85 ± 0.12), although the ratio may vary depending on the degree of decomposition of the corpse.

Development of dental charts according to tooth development and eruption for Turkish children and young adults

  • Karadayi, Beytullah;Afsin, Huseyin;Ozaslan, Abdi;Karadayi, Sukriye
    • Imaging Science in Dentistry
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    • v.44 no.2
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    • pp.103-113
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    • 2014
  • Purpose: In this study, we aimed to develop dental charts for Turkish children and young adults of both genders within the age group of 4.5-22.5 years according to tooth mineralization and eruption in a format similar to that proposed by AlQahtani et al. Materials and Methods: In total, 753 digital panoramic radiographs from 350 males and 403 females were assessed. The permanent teeth were evaluated according to the classification system described by Demirjian et al. The eruption stage was assessed with Bengston's system, which was modified by AlQahtani et al at four points. Results: Teeth generally developed earlier in females than in males. This was particularly notable in the age group of 5-14 years. However, this difference was usually visible in only one stage, not in all teeth. It has been determined that the mixed dentition period ended with the shedding of the second deciduous molars in both genders. Conclusion: The dental charts presented here included information that could be beneficial to dental clinicians in making appropriate diagnosis and planning orthodontic and surgical procedures. These charts also provided datasets for preliminary dental age estimation in Turkish children and young adults.

An Experience of Judicial Autopsy for a Death by Muscular Dystrophy: An Autopsy Case (근이영양증으로 인한 사망의 사법부검 사례 경험: 증례 보고)

  • Kim, Youn Shin;Park, Ji Hye
    • The Korean Journal of Legal Medicine
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    • v.42 no.4
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    • pp.159-163
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    • 2018
  • Progressive muscular dystrophy (PMD) is a primary muscle disease characterized by progressive muscle weakness and wasting, which is inherited by an X-linked recessive pattern and occurs mainly in males. There are several types of muscular dystrophies classified according to the distribution of predominant muscle weakness including Duchenne and Becker, Emery-Dreifuss, facioscapulohumeral, oculopharyngeal, and limb-girdle type. Clinical manifestations of PMD are clumsy, unsteady gait, pneumonia, heart failure, pulmonary edema, hydropericardium, hydrothorax, aspiration, syncopal attacks, and sudden cardiac death. The deceased was a 34-year-old man, and the onset of the first clinical symptom, gait disturbance, was in his late teens. His elder brother had the same disease and experienced brain death after a head trauma and died after mechanical ventilation was discontinued. After an autopsy, we found contracture of the joints, pseudohypertrophy of the calf, wasting and fat replacement of the thigh muscle, pericardial effusion (80 mL), fibrosis and fat replacement of the cardiac ventricular wall, pulmonary edema, and froth in the bronchus. The cause of death was heart failure and dyspnea due to muscular dystrophy. There was no sign or suspicion of foul play in his death.

Inappropriateness in Completing a Death Certificate (사망진단서 작성에 있어서 부적절성)

  • Lee, Hyun-Ji;Lee, Sang-Han
    • Journal of forensic and investigative science
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    • v.3 no.1
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    • pp.43-49
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    • 2008
  • This study was conducted to analyze the current problems in completing death certificates and to identify the correct method for completing death certificates. Total 298 death certificates in A hospital from January to December in 2005 were reviewed. There was only 88 death certificates (29.5%) without an error. The frequency of the major errors were 8.7% in 'mechanism of death listed instead of cause of death', 9.4% in 'competing causes', and 11.4% in 'improper sequencing'. The frequency of minor errors were 99.3% in 'absence of time intervals', 19.5% in 'repetition of same cause', 18.8% in "more than 2 causes listed in same space". Errors were common in the completion of death certificates in the middle sized hospital setting. It is very important to complete death certificate accurately in practice. Education in undergraduate course and persistent training in internship and residency program will be needed.

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Optimization of forensic identification through 3-dimensional imaging analysis of labial tooth surface using open-source software

  • Arofi Kurniawan;Aspalilah Alias;Mohd Yusmiaidil Putera Mohd Yusof;Anand Marya
    • Imaging Science in Dentistry
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    • v.54 no.1
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    • pp.63-69
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    • 2024
  • Purpose: The objective of this study was to determine the minimum number of teeth in the anterior dental arch that would yield accurate results for individual identification in forensic contexts. Materials and Methods: The study involved the analysis of 28 sets of 3-dimensional (3D) point cloud data, focused on the labial surface of the anterior teeth. These datasets were superimposed within each group in both genuine and imposter pairs. Group A incorporated data from the right to the left central incisor, group B from the right to the left lateral incisor, and group C from the right to the left canine. A comprehensive analysis was conducted, including the evaluation of root mean square error (RMSE) values and the distances resulting from the superimposition of dental arch segments. All analyses were conducted using CloudCompare version 2.12.4 (Telecom ParisTech and R&D, Kyiv, Ukraine). Results: The distances between genuine pairs in groups A, B, and C displayed an average range of 0.153 to 0.184mm. In contrast, distances for imposter pairs ranged from 0.338 to 0.522 mm. RMSE values for genuine pairs showed an average range of 0.166 to 0.177, whereas those for imposter pairs ranged from 0.424 to 0.638. A statistically significant difference was observed between the distances of genuine and imposter pairs(P<0.05). Conclusion: The exceptional performance observed for the labial surfaces of anterior teeth underscores their potential as a dependable criterion for accurate 3D dental identification. This was achieved by assessing a minimum of 4 teeth.

The Moderating Role of Binge Drinking on the Self-Assertiveness-Sexual Victimization Relationship among College Students (대학생의 자기주장과 성폭력 피해에서 폭음의 조절역할)

  • Hong, Hyeon-gi;Kim, Hee-song;Lee, Jung-eun;Jung, Sue-hyun;Ji, Hyung-ki;Kim, Ki-pyoung;Pyo, Chu-yun;Kim, Jong-han;Hyun, Myoung-Ho
    • Stress
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    • v.25 no.2
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    • pp.93-97
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    • 2017
  • Backgound: The present study was designed to investigate the moderating role of binge drinking on the relationship between self-assertiveness and sexual victimization among college students (N=393, male: 161, female: 232). We hypothesized that the relationship between self-assertiveness and sexual victimization is meaningful only when binge drinking is low, not high. Methods: Using an online site, participants filled out a packet of questionnaires for demographic information, their amount of unwanted sexual contact experience, and their rate of alcohol consumption. Results: In the result, binge drinking moderated the relationship between self-assertiveness and sexual victimization. For the high binge drinker group, high self-assertiveness was not a statistically significant predictor of sexual victimization. Conclusions: Although self-assertiveness is known to be a protective factor against sexual victimization, our results imply that self-assertiveness alone is not enough to lower sexual victimization. Binge drinking and self-assertiveness are considered together in sexual violence prevention programs.

The Evaluation of the Primary School Students' Knowledge and Recognition on the Sexual Assault (초등학생의 성폭력에 대한 지식 및 인식 연구 -경산시내 소재 5개교 6학년생을 중심으로-)

  • Yook, Jong-Hwa;Park, Hee-Kyung;Chae, Jong-Min
    • Journal of forensic and investigative science
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    • v.3 no.1
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    • pp.25-42
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    • 2008
  • As the age of the sex crime perpetrators and victims is going down, the importance of Sex Assault Prevention Education (SAPE) is on the rise. In order to see how many students are aware of the SAPE which are currently being conducted in the local schools. A total of 600 students from five different primary schools in Kyongsan City area were questioned with the questionnaire. On the whole, the level of acknowledgement on the sexual assault is estimated as 20.52 out of total point 53.00. The point in each question is shown as low as follows; The notion of Sexual Assault (9.88 out of 19), recognition of Sexual Assault (5.45 out 11), way to cope with the sexual assault (6.60 out of 11), and knowledge on the symptom induced by the sexual assault (4.04 out of 12). The SAPE should be taught to the student from the young age frequently. The efficiency of SAPE will be increased by the health-care teachers who have the professional knowledge with the case studies and teaching materials like CD-ROMs. The health-care teachers as the SAPE lecturers require continuous training.

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A Study on the Skull Injury Using MDCT image and ADINA F.E.M. Program (MDCT 영상과 ADINA 유한요소해석 프로그램을 활용한 두개골 손상 평가에 관한 연구)

  • Kim, Eui Soo;Kim, Jong Hyuk;Yang, Kyung Moo
    • Journal of the Korean Society of Safety
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    • v.28 no.1
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    • pp.1-5
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    • 2013
  • In this paper, the finite element analysis using ADINA has performed to investigate an accident that a man's head was damaged by the falling object. The simulation condition has defined by the point of forensic medicine view and the CCTV image analysis. From the CCTV image analysis, we expected that the sphere diameter of object is 15cm and object color is white. Assuming the falling mass is the ice mass, the results of the ADINA simulation show that a man's head can be broken by the falling ice mass.

The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene and Prostate Cancer Risk: a Meta-Analysis

  • Zhou, Qiao-Xia;Tang, Jian-Qiu;Zhao, Fen;Wei, Fu-Lin;Huang, Ying
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.13
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    • pp.5407-5413
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    • 2015
  • Background: Published data regarding associations between the P275A polymorphism in the macrophage scavenger receptor 1 (MSR1) gene and prostate cancer (PCa) risk are inconclusive. The aim of this study was to comprehensively evaluate the genetic risk of P275A polymorphism in MSR1 gene for PCa. Materials and Methods: A systematic literature search was carried out in Pubmed, Medline (Ovid), Embase, CBM, CNKI, Weipu, and Wanfang databases, covering all available publications (last search was performed on Apr 27, 2015). Statistical analysis was performed using Revman 5.2 and STATA 10.1 software. Results: A total of 5,017 cases and 4,869 controls in 12 case-control studies were included in this meta-analysis. When all groups were pooled, there was no evidence that the P275A polymorphism had a significant association with PCa under dominant (OR=0.93, 95%CI=0.81-1.06, and p=0.28), co-dominant (homogeneous OR=0.97, 95%CI=0.56-1.68, and p=0.92; heterogeneous OR=0.93, 95%CI=0.74-1.15, and p=0.49), recessive (OR=1.10, 95%CI=0.65-1.87, and p=0.73), over-dominant (OR=0.93, 95%CI=0.75-1.15, and p=0.50), and allelic (OR=0.95, 95%CI=0.77-1.16, and p=0.61) genetic models. For stratified analyses by ethnicity and study design, no significant associations were found in the white race, the yellow race, the black race and mixed ethnicity, and the population-based case-control (PCC) and hospital-based case-control (HCC) studies under all genetic models. Conclusions: Based on our meta-analysis, the P275A polymorphism in the MSR1 gene is unlikely to be a risk factor for PCa.