• Restorative Dentistry and Endodontics
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• 제36권3호
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• pp.211-218
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• 2011

연구목적: 의도적 재식술은 재근관치료와 치근단 수술이 곤란하거나 실패한 경우 치아를 유지하기 위한 치료 방법이다. 성공적인 의도적 재식술을 위해서 파절 없는 안전한 발치는 필수적인 과정이다. 이를 위해 최근 의도적 재식술을 위한 비외상성 안전 발치법이 소개되었다. 환자 및 방법: 분당서울대학교 병원 치과 보존과에서 의도적 재식술을 시행한 96명의 환자를 대상으로 하였다. 재근관 치료가 실패하였거나 해부학적 접근의 어려움 등으로 치근단 수술이 곤란한 경우나 환자가 거부한 경우를 대상으로 하였다. 술전교정적 정출술을 약 2-3주간 시행하여 치아의 동요도를 증가시키고 동시에 치주인대의 양을 증가시켰다. 이후 Physics Forceps를 이용하여 발치하였으며 결과에 대해 분석하였다. 결과: 96개의 치아는 상,하악 소구치 또는 대구치였다. 완전한 발치 성공은 93% (n = 89)였으며 제한적인 성공(치근의 일부가 부러짐)은 2% (n = 2), 골절제술을 동반하여 발치한 경우가 5% (n = 5)였다. 임상적인 성공률은 95%였으며 전체적인 발치 성공률은 100% 였다. 결론: 비외상성 안전 발치법은 의도적 재식술을 위해 재현성 있고 예측가능한 발치방법으로 볼 수 있다.

• Archives of Plastic Surgery
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• 제38권4호
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• pp.339-344
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• 2011

Purpose: The goal of cancer surgery is complete removal of cancer tissue and prevention of recurrence. Surgeons can change the surgical instruments after total resection of the cancer mass. The purpose of this procedure is to prevent dissemination of the cancer cells attached to the surgical instruments. Authors hypothesize the possibility of local recurrence caused by the cancer cells attached to the surgical instruments in the skin cancer cases. Methods: Skin cancers were induced by using DMBA-TPA two-stage carcinogenesis model in 10 of Balb/c mice. In 2-weeks, skin cancer was developed in all 10 mice. cancer cell attached surgical instruments were made by pinching the removed cancer tissue using Adson tissue forcep 10, 20, 30 times each. To count number of cancer cells in each forcep with different number of pinching was done, the forceps were washed in 30 mL of the normal saline and Cytospin preparation was done. To make recurrence models from cancer cell attached surgical instrument, three incisions were made in normal skin of each mouse, and local seeding was done by pinching subcutaneous tissue in 10, 20, 30 times each by using Adson teeth forceps mentioned above as cancer cell attached surgical instrument. Results: All skin cancers were squamous cell carcinoma. Local recurrences were developed in 7 mice (3 in 10 times forceping site, 2 in 20 times forceping and 3 in 30 times forceping). In the cytospin test, the mean number of squamous cells in 100 microscope was 28.6 in 10 times, 47.2 in 20 times, 93.6 in 30 times, respectively. P value was 0.002 in Wilcoxon-Sign test. Conclusion: The number of cell count was significantly increased as number of pinching was increased. And these cells are able to induce local recurrence by local seeding. Considering this result, authors are able to confirm that the minimal handling in cancer surgery is important factor to prevent local recurrence.

• 한국임상수의학회지
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• 제24권3호
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• pp.315-319
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• 2007

1년령, 암컷, 15 kg의 잡종견에서 위내시경을 이용한 경위장관 담낭절제술을 최소한의 복강경 도움아래에서 성공적으로 수행하였다. 내시경용 바늘 절개도를 이용하여 배쪽 유문부에서 위절개를 실시하였다. 위절개부를 통하여 내시경을 복강내로 진입한 다음 뒤쪽으로 돌려서 담낭쪽 시야를 확보하였다. 술야의 확보를 위해 복강경용 겸자를 이용하여 담낭의 바닥부위를 부드럽게 들어올렸다. 담낭관과 동맥을 내시경용 endoclip을 이용하여 3중 결찰하였다. 담낭관과 동맥을 절단한 후 내시경용 소작겸자와 바늘 절개도를 이용하여 담낭을 간으로부터 분리하였다. 분리된 담낭은 내시경을 이용해 입을 통하여 제거하고, 위절개부위는 내시경용 endoclip을 이용하여 봉합하였다. 술후 3일째 방사선검사 및 혈청화학검사를 통해 위봉합부위의 천공이 없음과 담즙의 누출이 없음을 확인하였다. 술후 16일째 위내시경과 복강경 검사를 실시하였다. 위내시경검사 결과 봉합부위가 완전히 유합 되었음을 확인하였고 복강경 검사를 통해 담낭절제부위와 위절개부의 장막에 대망막이 유착되어있음을 확인하였다. 본 연구는 개에서 자연개구부 내시경수술(NOTES)을 이용한 담낭절제술의 최초 보고로써 새로운 방법에 의한 담낭절제술에 대한 가능성을 제시한다.

• Parasites, Hosts and Diseases
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• 제48권1호
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• pp.57-59
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• 2010

A 59-year-old Korean man complained of a painless scrotal hard nodule and weak urine stream. The ultrasound scan revealed a 2.2-cm sized round heteroechogenic nodule located in the extratesticular area. Microscopic hematuria was detected in routine laboratory examinations. On scrotal exploration, multiple spargana were incidentally found in the mass and along the left spermatic cord. On cystoscopy, a 10-mm sized mucosal elevation was found in the right side of the bladder dome. After transurethral resection of the covered mucosa, larval tapeworms were removed from inside of the nodule by forceps. Plerocercoids of Spirometra erinacei was confirmed morphologically and also by PCR-sequencing analysis from the extracted tissue of the urinary bladder. So far as the literature is concerned, this is the first worm (PCR)-proven case of sparganosis in the urinary bladder.

• Journal of Chest Surgery
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• 제36권9호
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• pp.699-702
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• 2003

내시경을 이용한 기도 종양 절제술은 비침습적인 방법으로 개흉수술에 따른 각종 부작용을 감소할 수 있을 뿐만 아니라 폐실질을 보존할 수 있으며, 고령 등의 고위험군의 환자에서 안전하게 이용되고 있다. 기관내 종양(양성 지방종)과 기관지 내 종양(과오종)의 2예 환자에서 국소마취상태에서 굴곡형 기관지경직시하에 폴립제거용 기구와 전기소작술을 이용하여 완전절제를 시행하였다. 기관 내 지방 종환자는 술 후 6년째, 기관지내 과오종환자는 2년 6개월 째 재발없이 추적 중이다. 저자들의 방법이 환자에게 안전하며 좋은 시야에서 시술할 수 있는 장점이 있는 것으로 생각되었다.

• Journal of Chest Surgery
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• 제20권4호
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• pp.659-672
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• 1987

Nitrofen [2,4-dichlorophenyl-P-nitrophenyl ether] is a diphenyl ether herbicide used for pre and post-emergent control of broad leafed weeds. This chemical was known to induce a variety of congenital cardiovascular anomalies with diaphragmatic hernia and hydronephrosis in the rate fetuses. The present study was conducted to produce congenital cardiovascular anomalies in the rat fetuses by oral nitrofen administration at the indicated doses and days of gestation, and to find the characteristics of nitrofen-induced cardiovascular anomalies. All the observed fetuses were removed from the pregnant Sprague-Dawley rats sacrificed on the twenty-first day of gestation. They were preserved in 10 per cent formalin and dissection for examination were carried out under a dissecting microscope using forceps and scissors. Following results and conclusion were based on dissecting microscopic findings on 482 offsprings. 1. The eleventh day of gestation was the most sensitive day for nitrofen induction of congenital cardiovascular anomalies in the rat. This incidence was dose-related in rats exposed on the eleventh day of gestation. 2. Ventricular septal defect was the most common single anomaly that represented more than half of the total cardiovascular anomalies, followed by aortic arch anomalies and tetralogy of Fallot. 3. Cardiac anomalies derived from infundibular maldevelopment such as tetralogy of Fallot and pulmonary atresia with ventricular septal defect were only observed in the eleventh gestation day treated group. 4. Aortic arch anomalies were found in high frequency and the great majority were characteristically anomalous right subclavian artery with left aortic arch. Key words; nitrofen, congenital cardiovascular anomalies.

• 한국수정란이식학회지
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• 제32권2호
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• pp.47-52
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• 2017

As a part of the effort to improve post-transfer survival rate of embryos in Korean black goats, a technique for laparoscopic uterine transfer of blastocysts was carried out. A total of 26 transferrable embryos (morula to expanded blastocysts) were transferred to 13 recipient goats via transabdominal laparoscopic method. In consequence of our hormone protocol, 65% of the recipients (13/20) were found to have synchronized estrus. After confirmation of corpus luteum in each recipient goat, a Babcock laparoscopic forceps was inserted into the lower abdominal cavity to hold a uterine horn and fasten it near the peritoneum without causing injury. Then 7.5cm long 16G IV catheter was inserted directly into the uterine lumen through the abdominal wall. After removal of the stylet of the IV catheter, the embryo transfer tube (identical in size to the stylet and loaded with blastocysts) was inserted into the uterine lumen through the catheter to unload the embryos. Of the 13 estrus synchronized recipients, 9 were transferred blastocysts and 4 were transferred molurae (2 embryos in each recipient) in uterine ipsilateral to the ovary with corpus luteum. Four of the 9 recipients which blastocysts were transferred using this method has been confirmed pregnant (44.4% pregnancy rate).

• Clinical and Experimental Reproductive Medicine
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• 제39권4호
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• pp.187-192
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• 2012

Heterotopic pregnancy is rare event and the risk is increased with assisted reproductive technology procedures. Heterotopic cervical pregnancy is even more unusual. We report a rare case of heterotopic cervical pregnancy that was managed successfully. A 36-year-old women who conceived by IVF-ICSI was diagnosed with heterotopic cervical pregnancy. She visited the emergency room with vaginal bleeding at 5 weeks of gestation and underwent careful intracervical gestational sac reduction with forceps under abdominal guidance the next day. The postoperative course was uneventful and with regular check-ups, the intrauterine pregnancy (IUP) progressed unremarkably through 41 weeks with delivery of a healthy newborn. We reviewed a total of 37 cases of heterotopic pregnancy that have been reported in the English language literature. There have been many attempts to eliminate the cervical embryo while preserving the IUP, and complete cervical evacuation is important in order to avoid infection, bleeding, and premature birth.

• 대한예방한의학회지
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• 제7권1호
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• pp.47-53
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• 2003

쥐와 생쥐의 혈관내 봉한관을 채취하는 새로운 방법을 개발하였다. 복대정맥과 동맥에서 양끝을 겸자로 묶고 혈액을 뽑아냄으로써 부서진 봉한관 조각들을 찾아 광학 현미경으로 관찰하는 방법이다. 장점은 피브린이 없이 순수 봉한관을 얻는 것이고, 단점은 그 길이가 너무 짧은 점이다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1298-1301
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• 2003

The purpose of this research is to evaluate the effect of pre-load and fatigue life of the distracted one-level pedicle screw system. A spring, which acted as a substitute of the ligament, was installed in the one-level pedicle screw system before testing. The static and fatigue properties are now being tested, which includes 6mm rod to 6mm screw, 6mm rod to 6.5mm screw and 6.35mm rod to 6.5mm screw, under pre-load. Until now as test data were analyzed, 6mm rod to 6.5mm screw was found to have the best performances of stillness and fatigue lift, while 6mm rod to 6mm screw showed the shortest fatigue life. If the stiffness of screw was bigger than that of rod. the fatigue life was prolonged. The fatigue life of the distracted pedicle screw was proved to be shorter than that of the one-level pedicle screw system. So the fatigue life was shortened because of the effect of the spring on the flexibility and stiffness of the rod. In order to obtain the stability of the pedicle screw, more tests are under doing on this topic.